DK1896019T3 - Formulering af en thienopyridin-blodplade-aggregationshæmmer - Google Patents

Formulering af en thienopyridin-blodplade-aggregationshæmmer

Info

Publication number
DK1896019T3
DK1896019T3 DK06772240T DK06772240T DK1896019T3 DK 1896019 T3 DK1896019 T3 DK 1896019T3 DK 06772240 T DK06772240 T DK 06772240T DK 06772240 T DK06772240 T DK 06772240T DK 1896019 T3 DK1896019 T3 DK 1896019T3
Authority
DK
Denmark
Prior art keywords
formulation
platelet aggregation
aggregation inhibitor
thienopyridine
thienopyridine platelet
Prior art date
Application number
DK06772240T
Other languages
English (en)
Inventor
David Brian Dziennik
Tamara Beth Edelman
Peter Lloyd Oren
Robert Louis Ternik
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37198935&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1896019(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of DK1896019T3 publication Critical patent/DK1896019T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
DK06772240T 2005-06-10 2006-06-06 Formulering af en thienopyridin-blodplade-aggregationshæmmer DK1896019T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68918305P 2005-06-10 2005-06-10
PCT/US2006/021860 WO2006135605A2 (en) 2005-06-10 2006-06-06 Formulation of a thienopyridine platelet aggregation inhibitor

Publications (1)

Publication Number Publication Date
DK1896019T3 true DK1896019T3 (da) 2009-10-26

Family

ID=37198935

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06772240T DK1896019T3 (da) 2005-06-10 2006-06-06 Formulering af en thienopyridin-blodplade-aggregationshæmmer

Country Status (35)

Country Link
US (1) US20080176893A1 (da)
EP (1) EP1896019B1 (da)
JP (1) JP2008543755A (da)
KR (2) KR20100076050A (da)
CN (1) CN101193633B (da)
AR (1) AR054283A1 (da)
AT (1) ATE441413T1 (da)
AU (1) AU2006258102B2 (da)
BR (1) BRPI0611350B8 (da)
CA (1) CA2611668C (da)
CY (1) CY1109502T1 (da)
DE (1) DE602006008942D1 (da)
DK (1) DK1896019T3 (da)
DO (1) DOP2006000126A (da)
EA (1) EA011693B1 (da)
EC (1) ECSP077984A (da)
ES (1) ES2330373T3 (da)
HK (1) HK1116422A1 (da)
HR (1) HRP20090516T1 (da)
IL (1) IL187830A0 (da)
MA (1) MA29688B1 (da)
MX (1) MX2007015431A (da)
MY (1) MY151038A (da)
NO (1) NO20076317L (da)
NZ (1) NZ564003A (da)
PE (1) PE20070320A1 (da)
PL (1) PL1896019T3 (da)
PT (1) PT1896019E (da)
RS (1) RS51194B (da)
SI (1) SI1896019T1 (da)
TN (1) TNSN07466A1 (da)
TW (1) TWI318571B (da)
UA (1) UA91051C2 (da)
WO (1) WO2006135605A2 (da)
ZA (1) ZA200710697B (da)

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CN101594865A (zh) * 2006-12-07 2009-12-02 第一三共株式会社 含有低取代的羟基丙基纤维素的药物组合物
US20110201814A1 (en) * 2006-12-07 2011-08-18 Daiichi Sankyo Company Limited Method for producing solid preparation
JP5289975B2 (ja) * 2006-12-07 2013-09-11 第一三共株式会社 マンニトール又は乳糖を含有する固形製剤
EP2100606A4 (en) * 2006-12-07 2009-12-30 Daiichi Sankyo Co Ltd COATED PREPARATION OF A FILM HAVING IMPROVED STABILITY
BRPI0719398A2 (pt) * 2006-12-07 2015-03-31 Daiichi Sankyo Company Ltd E Ube Ind Ltd Composição farmacêutica.
JP2010512182A (ja) * 2006-12-07 2010-04-22 イーライ リリー アンド カンパニー プラスグレルのための製品
CA2679925C (en) * 2007-03-02 2012-10-02 Daiichi Sankyo Company, Limited Method for producing high-purity prasugrel hydrochloride
EP2152078B8 (en) 2007-04-27 2021-03-17 CyDex Pharmaceuticals, Inc. Formulations containing clopidogrel and sulfoalkyl ether cyclodextrin and methods of use
GB2450117A (en) * 2007-06-13 2008-12-17 Reckitt Benckiser Healthcare A water- and oxygen-occlusive blister tablet pack
US20110003847A1 (en) 2008-02-06 2011-01-06 Helm Ag Prasugrel Salts with Improved Properties
EP2107061A1 (en) * 2008-04-02 2009-10-07 Krka Tovarna Zdravil, D.D., Novo Mesto Process for the preparation of optically enriched clopidogrel
ATE482961T1 (de) * 2008-04-25 2010-10-15 Sandoz Ag Hydrogensulfat von 2-acetoxy-5-(a- cyclopropylcarbonyl-2-fluorbenzyl)-4,5,6,7- tetrahydrothienoä3,2-cüpyridin und dessen zubereitung
EP2398468B1 (en) 2009-02-17 2016-11-30 KRKA, D.D., Novo Mesto Pharmaceutical compositions comprising prasugrel base or its pharmaceutically acceptable acid addition salts and processes for their preparation
US8236782B2 (en) 2009-05-13 2012-08-07 Cydex Pharmaceuticals, Inc. Pharmaceutical compositions comprising prasugrel and cyclodextrin derivatives and methods of making and using the same
DE102009036646A1 (de) 2009-08-07 2011-02-10 Ratiopharm Gmbh Prasugrel in nicht-kristalliner Form und pharmazeutische Zusammensetzung davon
JP2013032289A (ja) * 2009-10-28 2013-02-14 Daiichi Sankyo Co Ltd ワックス安定製剤
WO2011052499A1 (ja) * 2009-10-28 2011-05-05 第一三共株式会社 貯蔵安定性が改善された医薬組成物
WO2011092720A2 (en) * 2010-02-01 2011-08-04 Msn Laboratories Limited Pharmaceutical composition of prasugrel and its pharmaceutically acceptable salts
TR201005900A1 (tr) 2010-07-19 2012-02-21 Sanovel İlaç San. Ve Ti̇c. A.Ş. Geliştirilmiş stabiliteye sahip prasugrel granülleri.
TR201006802A1 (tr) * 2010-08-17 2012-03-21 Sanovel İlaç San. Ve Ti̇c. A.Ş. Prasugrelin oral yolla dağılan formülasyonları.
TR201007926A1 (tr) 2010-07-19 2012-02-21 Sanovel İlaç San.Ve Ti̇c.A.Ş. Prasugrel tablet formülasyonları.
EP2409685A3 (en) 2010-07-19 2012-02-01 Sanovel Ilac Sanayi ve Ticaret A.S. Orally-disintegrating formulations of prasugrel
CZ2011872A3 (cs) 2011-12-22 2013-07-03 Zentiva, K.S. Farmaceutická formulace prasugrelu hydrobromidu
US8603537B2 (en) 2012-04-02 2013-12-10 Egis Pharmaceuticals Plc Prasugrel containing quickly released stable oral pharmaceutical compositions
WO2014060554A1 (en) 2012-10-19 2014-04-24 Sanovel Ilac Sanayi Ve Ticaret A.S. Prasugrel formulations
EP2722036A1 (en) 2012-10-19 2014-04-23 Sanovel Ilac Sanayi ve Ticaret A.S. Solid oral formulations of prasugrel
CN102993210A (zh) * 2012-12-19 2013-03-27 苏春华 一种吡啶并噻吩的新化合物
EP2979693A1 (en) 2014-08-01 2016-02-03 Zaklady Farmaceutyczne Polpharma SA Pharmaceutical composition comprising prasugrel or pharmaceutically acceptable salt thereof and process for its preparation
WO2016122421A1 (en) 2015-01-29 2016-08-04 Pharmactive Ilaç Sanayi Ve Ticaret A.Ş. Stable pharmaceutical compositions containing prasugrel base
EP3158993A1 (en) 2015-10-22 2017-04-26 Zaklady Farmaceutyczne Polpharma SA Process for preparing a tablet comprising prasugrel or pharmaceutically acceptable salt thereof
CN107304216A (zh) * 2016-04-20 2017-10-31 陕西合成药业股份有限公司 噻吩吡啶类衍生物及其制备方法和用途
HU231079B1 (hu) 2016-06-23 2020-06-29 Richter Gedeon Nyrt. Eljárás nagytisztaságú Prasugrel előállítására bromopentil szennyezés eltávolításával
GR1009230B (el) 2016-10-12 2018-02-22 Φαρματεν Αβεε Φαρμακευτικο σκευασμα που περιλαμβανει βεσυλικη πρασουγρελη

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI101150B (fi) * 1991-09-09 1998-04-30 Sankyo Co Menetelmä lääkeaineina käyttökelpoisten tetrahydrotienopyridiinin johd annaisten valmistamiseksi
JP4001199B2 (ja) * 2000-07-06 2007-10-31 第一三共株式会社 ヒドロピリジン誘導体酸付加塩
KR20100105763A (ko) * 2000-07-06 2010-09-29 다이이찌 산쿄 가부시키가이샤 히드로피리딘 유도체 산부가염
EP1243524A3 (en) * 2001-03-16 2004-04-07 Pfizer Products Inc. Pharmaceutical kit for oxygen-sensitive drugs
JP4394873B2 (ja) * 2001-12-19 2010-01-06 武田薬品工業株式会社 酸素に不安定な化合物を含有する固形組成物およびその安定化方法
SI21302A (sl) * 2002-10-11 2004-04-30 LEK farmacevtska dru�ba d.d. Stabiliziran farmacevtski izdelek z amorfno aktivno učinkovino
US20050020554A1 (en) * 2003-06-06 2005-01-27 Ahmed Salah U. Stability of hormone formulations
SK50462005A3 (sk) * 2003-08-05 2005-09-08 Zentiva, A. S. Spôsoby stabilizácie atorvastatínu

Also Published As

Publication number Publication date
BRPI0611350B8 (pt) 2021-05-25
IL187830A0 (en) 2008-04-13
CA2611668C (en) 2013-10-15
WO2006135605A3 (en) 2007-04-12
ATE441413T1 (de) 2009-09-15
JP2008543755A (ja) 2008-12-04
TNSN07466A1 (en) 2009-03-17
DOP2006000126A (es) 2006-12-15
CN101193633B (zh) 2011-12-14
CA2611668A1 (en) 2006-12-21
PT1896019E (pt) 2009-11-19
BRPI0611350B1 (pt) 2020-09-15
NO20076317L (no) 2008-02-29
US20080176893A1 (en) 2008-07-24
TW200718420A (en) 2007-05-16
PL1896019T3 (pl) 2010-01-29
DE602006008942D1 (en) 2009-10-15
AU2006258102B2 (en) 2011-09-15
HK1116422A1 (en) 2008-12-24
UA91051C2 (ru) 2010-06-25
ES2330373T3 (es) 2009-12-09
NZ564003A (en) 2011-07-29
BRPI0611350A2 (pt) 2010-12-07
MX2007015431A (es) 2008-02-21
KR20100076050A (ko) 2010-07-05
EA200702670A1 (ru) 2008-04-28
EP1896019A2 (en) 2008-03-12
RS51194B (sr) 2010-10-31
CY1109502T1 (el) 2014-08-13
HRP20090516T1 (en) 2009-10-31
PE20070320A1 (es) 2007-05-12
WO2006135605A2 (en) 2006-12-21
EP1896019B1 (en) 2009-09-02
ZA200710697B (en) 2009-08-26
ECSP077984A (es) 2008-01-23
AU2006258102A1 (en) 2006-12-21
EA011693B1 (ru) 2009-04-28
SI1896019T1 (sl) 2010-01-29
TWI318571B (en) 2009-12-21
MA29688B1 (fr) 2008-08-01
AR054283A1 (es) 2007-06-13
MY151038A (en) 2014-03-31
KR20080008413A (ko) 2008-01-23
CN101193633A (zh) 2008-06-04

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