AR069508A1 - Derivados de quinolina 057; un proceso para su preparacion; una composicion farmaceutica; la preparacion de esta y el uso del compuesto para preparar un medicamento - Google Patents

Derivados de quinolina 057; un proceso para su preparacion; una composicion farmaceutica; la preparacion de esta y el uso del compuesto para preparar un medicamento

Info

Publication number
AR069508A1
AR069508A1 ARP080105220A ARP080105220A AR069508A1 AR 069508 A1 AR069508 A1 AR 069508A1 AR P080105220 A ARP080105220 A AR P080105220A AR P080105220 A ARP080105220 A AR P080105220A AR 069508 A1 AR069508 A1 AR 069508A1
Authority
AR
Argentina
Prior art keywords
preparation
compound
quinolina
derivatives
prepare
Prior art date
Application number
ARP080105220A
Other languages
English (en)
Inventor
Simon David Guile
Toby Thompson
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of AR069508A1 publication Critical patent/AR069508A1/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Reproductive Health (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • AIDS & HIV (AREA)
  • Transplantation (AREA)
  • Hospice & Palliative Care (AREA)

Abstract

Los compuestos divulgados son utiles en el tratamiento de enfermedades inflamatorias, inmunitarias y cardiovasculares. Reivindicacion 1: Un compuesto caracterizado porque es de formula (1) o una de sus sales farmacéuticamente aceptables.
ARP080105220A 2007-11-30 2008-11-28 Derivados de quinolina 057; un proceso para su preparacion; una composicion farmaceutica; la preparacion de esta y el uso del compuesto para preparar un medicamento AR069508A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US99126507P 2007-11-30 2007-11-30

Publications (1)

Publication Number Publication Date
AR069508A1 true AR069508A1 (es) 2010-01-27

Family

ID=40676391

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP080105220A AR069508A1 (es) 2007-11-30 2008-11-28 Derivados de quinolina 057; un proceso para su preparacion; una composicion farmaceutica; la preparacion de esta y el uso del compuesto para preparar un medicamento

Country Status (10)

Country Link
US (1) US8106073B2 (es)
EP (1) EP2225222B1 (es)
JP (1) JP2011505356A (es)
AR (1) AR069508A1 (es)
AT (1) ATE524458T1 (es)
ES (1) ES2370960T3 (es)
HK (1) HK1148002A1 (es)
PE (1) PE20091036A1 (es)
TW (1) TW200932229A (es)
WO (1) WO2009070116A1 (es)

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JP2010522227A (ja) * 2007-03-22 2010-07-01 アストラゼネカ・アクチエボラーグ 炎症性疾患の処置のためのキノリン誘導体
US8106073B2 (en) 2007-11-30 2012-01-31 Astrazeneca Ab Quinoline derivatives 057
ES2575154T3 (es) * 2009-12-17 2016-06-24 Merck Sharp & Dohme Corp. Moduladores alostéricos positivos del receptor M1 de quinolina amida
WO2012110190A1 (en) 2011-02-17 2012-08-23 Affectis Pharmaceuticals Ag Novel p2x7r antagonists and their use
WO2012163456A1 (en) 2011-05-27 2012-12-06 Affectis Pharmaceuticals Ag Novel p2x7r antagonists and their use
WO2012163792A1 (en) 2011-05-27 2012-12-06 Affectis Pharmaceuticals Ag Novel p2x7r antagonists and their use
CN103687860B (zh) 2011-07-22 2016-06-08 埃科特莱茵药品有限公司 作为p2x7受体拮抗剂的杂环酰胺衍生物
KR102033190B1 (ko) 2012-01-20 2019-10-16 이도르시아 파마슈티컬스 리미티드 Ｐ２ｘ７ 수용체 길항제로서의 헤테로시클릭 아미드 유도체
US9718774B2 (en) 2012-12-12 2017-08-01 Idorsia Pharmaceuticals Ltd Indole carboxamide derivatives as P2X7 receptor antagonist
EP2935211B1 (en) 2012-12-18 2016-11-09 Actelion Pharmaceuticals Ltd. Indole carboxamide derivatives as p2x7 receptor antagonists
CA2896790C (en) 2013-01-22 2022-05-10 Actelion Pharmaceuticals Ltd Heterocyclic amide derivatives as p2x7 receptor antagonists
US9388198B2 (en) 2013-01-22 2016-07-12 Actelion Pharmaceuticals Ltd. Heterocyclic amide derivatives as P2X7 receptor antagonists
AR100724A1 (es) * 2014-06-05 2016-10-26 Merck Patent Gmbh Derivados de quinolina y su uso en enfermedades neurodegenerativas
MA55805A (fr) 2019-05-03 2022-03-09 Flagship Pioneering Innovations V Inc Métodes de modulation de l'activité immunitaire

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US20090143428A1 (en) 2009-06-04
ATE524458T1 (de) 2011-09-15
PE20091036A1 (es) 2009-08-15
US8106073B2 (en) 2012-01-31
EP2225222B1 (en) 2011-09-14
HK1148002A1 (en) 2011-08-26
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WO2009070116A1 (en) 2009-06-04
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