SE0402925D0 - Novel Compounds - Google Patents
Novel CompoundsInfo
- Publication number
- SE0402925D0 SE0402925D0 SE0402925A SE0402925A SE0402925D0 SE 0402925 D0 SE0402925 D0 SE 0402925D0 SE 0402925 A SE0402925 A SE 0402925A SE 0402925 A SE0402925 A SE 0402925A SE 0402925 D0 SE0402925 D0 SE 0402925D0
- Authority
- SE
- Sweden
- Prior art keywords
- sup
- novel compounds
- therapy
- pharmaceutically acceptable
- formula
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
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- A61P11/06—Antiasthmatics
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Virology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Reproductive Health (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Vascular Medicine (AREA)
- AIDS & HIV (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0402925A SE0402925D0 (sv) | 2004-11-30 | 2004-11-30 | Novel Compounds |
JP2007544304A JP2008521894A (ja) | 2004-11-30 | 2005-11-28 | 新規化合物 |
CNA200580047483XA CN101111488A (zh) | 2004-11-30 | 2005-11-28 | 新型化合物 |
US11/720,359 US20080182874A1 (en) | 2004-11-30 | 2005-11-28 | Novel Compounds |
EP05810057A EP1824838A1 (en) | 2004-11-30 | 2005-11-28 | Novel compounds |
PCT/SE2005/001782 WO2006059945A1 (en) | 2004-11-30 | 2005-11-28 | Novel compounds |
UY29234A UY29234A1 (es) | 2004-11-30 | 2005-11-29 | Derivados de adamantano, composiciones farmacéuticas que los contienen, procedimientos de preparación de ambos y aplicaciones. |
ARP050104990A AR052330A1 (es) | 2004-11-30 | 2005-11-29 | Derivados de adamantano que comprenden quinoleinas sustituidas |
TW094141987A TW200626553A (en) | 2004-11-30 | 2005-11-30 | Novel compounds |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0402925A SE0402925D0 (sv) | 2004-11-30 | 2004-11-30 | Novel Compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
SE0402925D0 true SE0402925D0 (sv) | 2004-11-30 |
Family
ID=33538422
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE0402925A SE0402925D0 (sv) | 2004-11-30 | 2004-11-30 | Novel Compounds |
Country Status (9)
Country | Link |
---|---|
US (1) | US20080182874A1 (sv) |
EP (1) | EP1824838A1 (sv) |
JP (1) | JP2008521894A (sv) |
CN (1) | CN101111488A (sv) |
AR (1) | AR052330A1 (sv) |
SE (1) | SE0402925D0 (sv) |
TW (1) | TW200626553A (sv) |
UY (1) | UY29234A1 (sv) |
WO (1) | WO2006059945A1 (sv) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI258462B (en) | 1999-12-17 | 2006-07-21 | Astrazeneca Ab | Adamantane derivative compounds, process for preparing the same and pharmaceutical composition comprising the same |
GB0312609D0 (en) | 2003-06-02 | 2003-07-09 | Astrazeneca Ab | Novel compounds |
WO2008013494A1 (en) * | 2006-07-27 | 2008-01-31 | Astrazeneca Ab | Quinoline derivatives as p2x7 receptor antagonist and their use in the treatment of rheumatoid arthritis, osteoarthritis, copd and ibd |
ES2388454T3 (es) | 2007-03-22 | 2012-10-15 | Astrazeneca Ab | Derivados de quinolina para el tratamiento de enfermedades inflamatorias |
PE20091036A1 (es) * | 2007-11-30 | 2009-08-15 | Astrazeneca Ab | Derivado de quinolina como antagonista del receptor p2x7 |
PL2105164T3 (pl) | 2008-03-25 | 2011-05-31 | Affectis Pharmaceuticals Ag | Nowi antagoniści P2X7R i ich zastosowanie |
PL2243772T3 (pl) | 2009-04-14 | 2012-05-31 | Affectis Pharmaceuticals Ag | Nowi antagoniści p2x7r i ich zastosowanie |
WO2011141194A1 (en) | 2010-05-14 | 2011-11-17 | Affectis Pharmaceuticals Ag | Novel methods for the preparation of p2x7r antagonists |
ES2553771T3 (es) * | 2010-10-08 | 2015-12-11 | Nivalis Therapeutics, Inc. | Nuevos compuestos de quinolina sustituidos como inhibidores de la S-nitrosoglutatión reductasa |
WO2012110190A1 (en) | 2011-02-17 | 2012-08-23 | Affectis Pharmaceuticals Ag | Novel p2x7r antagonists and their use |
WO2012163792A1 (en) | 2011-05-27 | 2012-12-06 | Affectis Pharmaceuticals Ag | Novel p2x7r antagonists and their use |
WO2012163456A1 (en) | 2011-05-27 | 2012-12-06 | Affectis Pharmaceuticals Ag | Novel p2x7r antagonists and their use |
AR087274A1 (es) | 2011-07-22 | 2014-03-12 | Actelion Pharmaceuticals Ltd | Derivados de amidas heterociclicas como antagonistas de receptores p2x7 |
WO2013108227A1 (en) | 2012-01-20 | 2013-07-25 | Actelion Pharmaceuticals Ltd | Heterocyclic amide derivatives as p2x7 receptor antagonists |
AU2013356850B2 (en) | 2012-12-12 | 2018-02-01 | Idorsia Pharmaceuticals Ltd | Indole carboxamide derivatives as P2X7 receptor antagonists |
CN104854087B (zh) | 2012-12-18 | 2017-03-22 | 埃科特莱茵药品有限公司 | 作为p2x7受体拮抗剂的吲哚羧酰胺衍生物 |
CN104918617B (zh) | 2013-01-22 | 2017-05-10 | 埃科特莱茵药品有限公司 | 作为p2x7受体拮抗剂的杂环酰胺衍生物 |
CN104918946B (zh) | 2013-01-22 | 2017-03-29 | 埃科特莱茵药品有限公司 | 作为p2x7受体拮抗剂的杂环酰胺衍生物 |
AU2015269598B2 (en) * | 2014-06-05 | 2019-11-14 | Merck Patent Gmbh | Novel quinoline derivatives and their use in neurodegenerative diseases |
CN105601566A (zh) * | 2016-02-02 | 2016-05-25 | 张敏 | 一种护理烧伤后感染的药物组合物 |
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US3471491A (en) * | 1967-08-28 | 1969-10-07 | Squibb & Sons Inc | Adamantyl-s-triazines |
US3464998A (en) * | 1968-03-04 | 1969-09-02 | Searle & Co | Adamantyl esters and amides of pyridinecarboxylic acids |
US4349552A (en) * | 1978-10-30 | 1982-09-14 | Fujisawa Pharmaceutical Company, Ltd. | 5-Fluorouracil derivatives, and their pharmaceutical compositions |
US4751292A (en) * | 1985-07-02 | 1988-06-14 | The Plant Cell Research Institute, Inc. | Adamantyl purines |
US5399564A (en) * | 1991-09-03 | 1995-03-21 | Dowelanco | N-(4-pyridyl or 4-quinolinyl) arylacetamide and 4-(aralkoxy or aralkylamino) pyridine pesticides |
PL329922A1 (en) * | 1996-05-20 | 1999-04-26 | Darwin Discovery Ltd | Quinoline carboxamides as inhibitors of the tumour necrosis factor and of phosphodiesterase |
SE9704544D0 (sv) * | 1997-12-05 | 1997-12-05 | Astra Pharma Prod | Novel compounds |
SE9704545D0 (sv) * | 1997-12-05 | 1997-12-05 | Astra Pharma Prod | Novel compounds |
NZ514477A (en) * | 1999-04-09 | 2003-04-29 | Astrazeneca Ab | Adamantane derivatives |
SE9904505D0 (sv) * | 1999-12-09 | 1999-12-09 | Astra Pharma Prod | Novel compounds |
TWI258462B (en) * | 1999-12-17 | 2006-07-21 | Astrazeneca Ab | Adamantane derivative compounds, process for preparing the same and pharmaceutical composition comprising the same |
GB0013737D0 (en) * | 2000-06-07 | 2000-07-26 | Astrazeneca Ab | Novel compounds |
JP4523273B2 (ja) * | 2001-07-02 | 2010-08-11 | ナームローゼ・フエンノートチヤツプ・オルガノン | テトラヒドロキノリン誘導体 |
WO2003042190A1 (en) * | 2001-11-12 | 2003-05-22 | Pfizer Products Inc. | N-alkyl-adamantyl derivatives as p2x7-receptor antagonists |
SE0103836D0 (sv) * | 2001-11-16 | 2001-11-16 | Astrazeneca Ab | Novel compounds |
US6908939B2 (en) * | 2001-12-21 | 2005-06-21 | Galderma Research & Development S.N.C. | Biaromatic ligand activators of PPARγ receptors |
SE0200920D0 (sv) * | 2002-03-25 | 2002-03-25 | Astrazeneca Ab | Novel compounds |
SE0300445D0 (sv) * | 2003-02-18 | 2003-02-18 | Astrazeneca Ab | New combination |
SE0300480D0 (sv) * | 2003-02-21 | 2003-02-21 | Astrazeneca Ab | Novel compounds |
TW200507829A (en) * | 2003-05-29 | 2005-03-01 | Astrazeneca Ab | New combination |
US20070010497A1 (en) * | 2003-05-29 | 2007-01-11 | Nigel Boughton-Smith | Pharmaceutical composition comprising a p2x7 antagonist and sulfasalazine |
WO2004105796A1 (en) * | 2003-05-29 | 2004-12-09 | Astrazeneca Ab | A pharmaceutical composition containing a p2x7 receptor antagonist and methotrexate |
SE0302192D0 (sv) * | 2003-08-08 | 2003-08-08 | Astrazeneca Ab | Novel compounds |
SE0302488D0 (sv) * | 2003-09-18 | 2003-09-18 | Astrazeneca Ab | New combination |
-
2004
- 2004-11-30 SE SE0402925A patent/SE0402925D0/sv unknown
-
2005
- 2005-11-28 JP JP2007544304A patent/JP2008521894A/ja active Pending
- 2005-11-28 US US11/720,359 patent/US20080182874A1/en not_active Abandoned
- 2005-11-28 WO PCT/SE2005/001782 patent/WO2006059945A1/en active Application Filing
- 2005-11-28 CN CNA200580047483XA patent/CN101111488A/zh active Pending
- 2005-11-28 EP EP05810057A patent/EP1824838A1/en not_active Withdrawn
- 2005-11-29 UY UY29234A patent/UY29234A1/es not_active Application Discontinuation
- 2005-11-29 AR ARP050104990A patent/AR052330A1/es not_active Application Discontinuation
- 2005-11-30 TW TW094141987A patent/TW200626553A/zh unknown
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TW200626553A (en) | 2006-08-01 |
UY29234A1 (es) | 2006-06-30 |
CN101111488A (zh) | 2008-01-23 |
JP2008521894A (ja) | 2008-06-26 |
WO2006059945A1 (en) | 2006-06-08 |
AR052330A1 (es) | 2007-03-14 |
US20080182874A1 (en) | 2008-07-31 |
EP1824838A1 (en) | 2007-08-29 |
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