HK1148002A1 - A quinoline derivative acting as a p2x7-receptor antagonist - Google Patents

A quinoline derivative acting as a p2x7-receptor antagonist

Info

Publication number
HK1148002A1
HK1148002A1 HK11102084.0A HK11102084A HK1148002A1 HK 1148002 A1 HK1148002 A1 HK 1148002A1 HK 11102084 A HK11102084 A HK 11102084A HK 1148002 A1 HK1148002 A1 HK 1148002A1
Authority
HK
Hong Kong
Prior art keywords
receptor antagonist
quinoline derivative
derivative acting
acting
quinoline
Prior art date
Application number
HK11102084.0A
Other languages
English (en)
Inventor
Simon David Guile
Toby Thompson
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of HK1148002A1 publication Critical patent/HK1148002A1/xx

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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HK11102084.0A 2007-11-30 2011-03-02 A quinoline derivative acting as a p2x7-receptor antagonist HK1148002A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US99126507P 2007-11-30 2007-11-30
PCT/SE2008/051370 WO2009070116A1 (en) 2007-11-30 2008-11-28 A quinoline derivative acting as a p2x7-receptor antagonist

Publications (1)

Publication Number Publication Date
HK1148002A1 true HK1148002A1 (en) 2011-08-26

Family

ID=40676391

Family Applications (1)

Application Number Title Priority Date Filing Date
HK11102084.0A HK1148002A1 (en) 2007-11-30 2011-03-02 A quinoline derivative acting as a p2x7-receptor antagonist

Country Status (10)

Country Link
US (1) US8106073B2 (es)
EP (1) EP2225222B1 (es)
JP (1) JP2011505356A (es)
AR (1) AR069508A1 (es)
AT (1) ATE524458T1 (es)
ES (1) ES2370960T3 (es)
HK (1) HK1148002A1 (es)
PE (1) PE20091036A1 (es)
TW (1) TW200932229A (es)
WO (1) WO2009070116A1 (es)

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WO2012163456A1 (en) 2011-05-27 2012-12-06 Affectis Pharmaceuticals Ag Novel p2x7r antagonists and their use
WO2012163792A1 (en) 2011-05-27 2012-12-06 Affectis Pharmaceuticals Ag Novel p2x7r antagonists and their use
ES2574840T3 (es) 2011-07-22 2016-06-22 Actelion Pharmaceuticals Ltd. Derivados de amidas heterocíclicas como antagonistas de receptores p2x7
PL2804865T3 (pl) 2012-01-20 2016-06-30 Idorsia Pharmaceuticals Ltd Heterocykliczne pochodne amidowe jako antagoniści receptora p2x7
CN104812749B (zh) 2012-12-12 2016-12-14 埃科特莱茵药品有限公司 作为p2x7受体拮抗剂的吲哚羧酰胺衍生物
JP6295270B2 (ja) 2012-12-18 2018-03-14 イドーシア ファーマシューティカルズ リミテッドＩｄｏｒｓｉａ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｔｄ Ｐ２ｘ７受容体アンタゴニストとしてのインドールカルボキサミド誘導体
CA2897459C (en) 2013-01-22 2021-03-02 Actelion Pharmaceuticals Ltd Heterocyclic amide derivatives as p2x7 receptor antagonists
JP6282016B2 (ja) 2013-01-22 2018-02-21 イドーシア ファーマシューティカルズ リミテッドＩｄｏｒｓｉａ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｔｄ Ｐ２ｘ７受容体アンタゴニストとしての複素環アミド誘導体
WO2015187905A1 (en) * 2014-06-05 2015-12-10 Merck Patent Gmbh Novel quinoline derivatives and their use in neurodegenerative diseases
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AR069508A1 (es) 2010-01-27
US8106073B2 (en) 2012-01-31
ES2370960T3 (es) 2011-12-26
US20090143428A1 (en) 2009-06-04
EP2225222A1 (en) 2010-09-08
JP2011505356A (ja) 2011-02-24
ATE524458T1 (de) 2011-09-15
EP2225222B1 (en) 2011-09-14
PE20091036A1 (es) 2009-08-15
TW200932229A (en) 2009-08-01
WO2009070116A1 (en) 2009-06-04
EP2225222A4 (en) 2010-12-01

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