PL2234987T3 - Pochodne perhydrochinoksaliny jako leki przeciwbólowe - Google Patents
Pochodne perhydrochinoksaliny jako leki przeciwbóloweInfo
- Publication number
- PL2234987T3 PL2234987T3 PL08864093T PL08864093T PL2234987T3 PL 2234987 T3 PL2234987 T3 PL 2234987T3 PL 08864093 T PL08864093 T PL 08864093T PL 08864093 T PL08864093 T PL 08864093T PL 2234987 T3 PL2234987 T3 PL 2234987T3
- Authority
- PL
- Poland
- Prior art keywords
- analgesics
- perhydroquinoxaline
- derivatives
- perhydroquinoxaline derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/42—Benzopyrazines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Ophthalmology & Optometry (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102007062550A DE102007062550A1 (de) | 2007-12-20 | 2007-12-20 | Perhydrochinoxalin-Derivate |
PCT/EP2008/068000 WO2009080745A2 (de) | 2007-12-20 | 2008-12-19 | Perhydrochinoxalin-derivate |
EP08864093A EP2234987B1 (de) | 2007-12-20 | 2008-12-19 | Perhydrochinoxalin-derivate als analgetika |
Publications (1)
Publication Number | Publication Date |
---|---|
PL2234987T3 true PL2234987T3 (pl) | 2013-05-31 |
Family
ID=40689885
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL08864093T PL2234987T3 (pl) | 2007-12-20 | 2008-12-19 | Pochodne perhydrochinoksaliny jako leki przeciwbólowe |
Country Status (13)
Country | Link |
---|---|
US (1) | US8309725B2 (pl) |
EP (1) | EP2234987B1 (pl) |
JP (1) | JP5253515B2 (pl) |
KR (1) | KR101314802B1 (pl) |
CN (2) | CN101903358A (pl) |
CA (1) | CA2708502C (pl) |
DE (1) | DE102007062550A1 (pl) |
DK (1) | DK2234987T3 (pl) |
ES (1) | ES2401418T3 (pl) |
HK (1) | HK1192881A1 (pl) |
PL (1) | PL2234987T3 (pl) |
RU (1) | RU2482113C2 (pl) |
WO (1) | WO2009080745A2 (pl) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2697238B1 (en) * | 2011-04-08 | 2019-03-20 | Laurus Labs Limited | Solid forms of antiretroviral compounds, process for the preparation and their pharmaceutical composition thereof |
WO2014184356A1 (en) | 2013-05-17 | 2014-11-20 | Dr. August Wolff Gmbh & Co. Kg Arzneimittel | Perhydroquinoxaline derivatives useful as analgesics |
MX2015015755A (es) | 2013-05-17 | 2016-03-11 | Wolff August Gmbh & Co Kg Arzneimittel Dr | Derivados de perhidroquinoxalina utiles como analgesicos. |
WO2016079109A1 (en) | 2014-11-18 | 2016-05-26 | Dr. August Wolff Gmbh & Co. Kg Arzneimittel | Process for the preparation of perhydroquinoxaline derivatives |
EP3723751A4 (en) * | 2017-12-08 | 2021-07-07 | The Rockefeller University | PYRANO [3,4-B] PYRAZIN-KAPPA-OPIOID RECEPTOR LIGANDS FOR THE TREATMENT OF ADDICTION, PRURITUS, PAIN AND INFLAMMATION |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6303611B1 (en) * | 1996-03-08 | 2001-10-16 | Adolor Corporation | Kappa agonist compounds and pharmaceutical formulations thereof |
US5763445A (en) * | 1996-03-08 | 1998-06-09 | Adolor Corporation | Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith |
US6355641B1 (en) * | 1999-03-17 | 2002-03-12 | Syntex (U.S.A.) Llc | Oxazolone derivatives and uses thereof |
WO2000055143A1 (en) * | 1999-03-17 | 2000-09-21 | F. Hoffmann-La Roche Ag | Oxazolone derivatives and their use as alpha-1 adrenoreceptor modulators |
US6393611B1 (en) * | 2001-03-01 | 2002-05-28 | Kathryn H. Thompson | Women's under/outer garment |
RU2224752C2 (ru) * | 2002-01-31 | 2004-02-27 | Пермская государственная фармацевтическая академия | 3-дибензоилметилен-7-нитро-2-хиноксалон, проявляющий анальгетическую активность |
SE0302324D0 (sv) * | 2003-08-28 | 2003-08-28 | Astrazeneca Ab | Novel compounds |
CN1966500B (zh) * | 2005-11-17 | 2011-03-30 | 中国科学院上海药物研究所 | 一类喹喔啉类衍生物、制法及用途 |
-
2007
- 2007-12-20 DE DE102007062550A patent/DE102007062550A1/de not_active Withdrawn
-
2008
- 2008-12-19 RU RU2010130187/04A patent/RU2482113C2/ru not_active IP Right Cessation
- 2008-12-19 PL PL08864093T patent/PL2234987T3/pl unknown
- 2008-12-19 EP EP08864093A patent/EP2234987B1/de not_active Not-in-force
- 2008-12-19 CA CA2708502A patent/CA2708502C/en not_active Expired - Fee Related
- 2008-12-19 KR KR1020107015571A patent/KR101314802B1/ko not_active IP Right Cessation
- 2008-12-19 US US12/809,243 patent/US8309725B2/en not_active Expired - Fee Related
- 2008-12-19 JP JP2010538752A patent/JP5253515B2/ja not_active Expired - Fee Related
- 2008-12-19 CN CN2008801230484A patent/CN101903358A/zh active Pending
- 2008-12-19 CN CN201410056987.9A patent/CN103804359B/zh not_active Expired - Fee Related
- 2008-12-19 WO PCT/EP2008/068000 patent/WO2009080745A2/de active Application Filing
- 2008-12-19 ES ES08864093T patent/ES2401418T3/es active Active
- 2008-12-19 DK DK08864093.3T patent/DK2234987T3/da active
-
2014
- 2014-06-13 HK HK14105654.0A patent/HK1192881A1/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
RU2010130187A (ru) | 2012-01-27 |
US8309725B2 (en) | 2012-11-13 |
CN103804359B (zh) | 2015-11-25 |
EP2234987A2 (de) | 2010-10-06 |
HK1192881A1 (zh) | 2014-09-05 |
US20100311761A1 (en) | 2010-12-09 |
CN101903358A (zh) | 2010-12-01 |
JP2011506574A (ja) | 2011-03-03 |
WO2009080745A2 (de) | 2009-07-02 |
ES2401418T3 (es) | 2013-04-19 |
CN103804359A (zh) | 2014-05-21 |
CA2708502C (en) | 2013-02-12 |
DK2234987T3 (da) | 2013-02-11 |
EP2234987B1 (de) | 2012-12-12 |
KR101314802B1 (ko) | 2013-10-10 |
WO2009080745A3 (de) | 2009-11-12 |
KR20100096242A (ko) | 2010-09-01 |
CA2708502A1 (en) | 2009-07-02 |
RU2482113C2 (ru) | 2013-05-20 |
JP5253515B2 (ja) | 2013-07-31 |
DE102007062550A1 (de) | 2009-06-25 |
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