AR046696A1 - Aplicador auto-accionante para grupo de microproyecciones - Google Patents

Aplicador auto-accionante para grupo de microproyecciones

Info

Publication number
AR046696A1
AR046696A1 ARP040103972A ARP040103972A AR046696A1 AR 046696 A1 AR046696 A1 AR 046696A1 AR P040103972 A ARP040103972 A AR P040103972A AR P040103972 A ARP040103972 A AR P040103972A AR 046696 A1 AR046696 A1 AR 046696A1
Authority
AR
Argentina
Prior art keywords
applicator
self
microprojection group
microprojections
housing
Prior art date
Application number
ARP040103972A
Other languages
English (en)
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of AR046696A1 publication Critical patent/AR046696A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/20—Surgical instruments, devices or methods, e.g. tourniquets for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205—Vaccinating by means of needles or other puncturing devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
    • A61B17/92—Impactors or extractors, e.g. for removing intramedullary devices
    • A61B2017/922—Devices for impaction, impact element
    • A61B2017/924—Impact element driving means
    • A61B2017/925—Impact element driving means a spring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0038—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a channel at the side surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Dermatology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Un aplicador para aplicar un componente con microproyecciones al estrato córneo de un paciente que tiene un alojamiento, un émbolo movible dentro del alojamiento y un casquete adaptado para activar el aplicador. El aplicador es auto-ajustante y auto- disparante. Un sistema de administración transdérmica de un agente biológicamente activo ( hormonas, antígenos), que comprende: un sistema de parche que contiene una formulación de hidrogel, un componente con microproyecciones y un aplicador.
ARP040103972A 2003-10-31 2004-10-29 Aplicador auto-accionante para grupo de microproyecciones AR046696A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US51618203P 2003-10-31 2003-10-31

Publications (1)

Publication Number Publication Date
AR046696A1 true AR046696A1 (es) 2005-12-21

Family

ID=34572872

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP040103972A AR046696A1 (es) 2003-10-31 2004-10-29 Aplicador auto-accionante para grupo de microproyecciones

Country Status (13)

Country Link
US (2) US7097631B2 (es)
EP (1) EP1680154B1 (es)
JP (1) JP4682144B2 (es)
KR (1) KR20060099523A (es)
CN (1) CN100571643C (es)
AR (1) AR046696A1 (es)
AT (1) ATE539687T1 (es)
AU (1) AU2004287414B2 (es)
BR (1) BRPI0415629A (es)
CA (1) CA2543641A1 (es)
ES (1) ES2377647T3 (es)
TW (1) TW200633675A (es)
WO (1) WO2005044333A2 (es)

Families Citing this family (269)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA975326B (en) * 1996-06-18 1998-01-14 Alza Corp Device and method for enhancing transdermal flux of agents being delivered or sampled.
US6036924A (en) 1997-12-04 2000-03-14 Hewlett-Packard Company Cassette of lancet cartridges for sampling blood
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
HUP0303576A2 (en) * 2000-10-13 2004-01-28 Alza Corp Microprotrusion member retainer for impact applicator
US7419481B2 (en) * 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
AU9682801A (en) * 2000-10-13 2002-04-22 Alza Corp Apparatus and method for piercing skin with microprotrusions
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
US6821281B2 (en) * 2000-10-16 2004-11-23 The Procter & Gamble Company Microstructures for treating and conditioning skin
HUP0302924A2 (en) * 2000-10-26 2003-12-29 Alza Corp Transdermal drug delivery devices having coated microprotrusions
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
US6855372B2 (en) * 2001-03-16 2005-02-15 Alza Corporation Method and apparatus for coating skin piercing microprojections
US20020193729A1 (en) * 2001-04-20 2002-12-19 Cormier Michel J.N. Microprojection array immunization patch and method
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
DE60239132D1 (de) 2001-06-12 2011-03-24 Pelikan Technologies Inc Gerät zur erhöhung der erfolgsrate im hinblick auf die durch einen fingerstich erhaltene blutausbeute
US7041068B2 (en) 2001-06-12 2006-05-09 Pelikan Technologies, Inc. Sampling module device and method
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
EP1395185B1 (en) 2001-06-12 2010-10-27 Pelikan Technologies Inc. Electric lancet actuator
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
ES2336081T3 (es) 2001-06-12 2010-04-08 Pelikan Technologies Inc. Dispositivo de puncion de auto-optimizacion con medios de adaptacion a variaciones temporales en las propiedades cutaneas.
AU2002348683A1 (en) 2001-06-12 2002-12-23 Pelikan Technologies, Inc. Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
EP1404232B1 (en) 2001-06-12 2009-12-02 Pelikan Technologies Inc. Blood sampling apparatus and method
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7717863B2 (en) 2002-04-19 2010-05-18 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US7175642B2 (en) 2002-04-19 2007-02-13 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US7371247B2 (en) 2002-04-19 2008-05-13 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8360992B2 (en) 2002-04-19 2013-01-29 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US7648468B2 (en) 2002-04-19 2010-01-19 Pelikon Technologies, Inc. Method and apparatus for penetrating tissue
US7892185B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US7291117B2 (en) 2002-04-19 2007-11-06 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7226461B2 (en) 2002-04-19 2007-06-05 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with sterility barrier release
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
GB0210397D0 (en) * 2002-05-07 2002-06-12 Ferring Bv Pharmaceutical formulations
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
EP1624913B1 (en) 2003-05-08 2010-07-21 Novo Nordisk A/S Skin mountable injection device with a detachable needle insertion actuation portion
EP1475113A1 (en) * 2003-05-08 2004-11-10 Novo Nordisk A/S External needle inserter
ATE392223T1 (de) 2003-05-08 2008-05-15 Novo Nordisk As Interne nadeleinführvorrichtung
EP1628567B1 (en) 2003-05-30 2010-08-04 Pelikan Technologies Inc. Method and apparatus for fluid injection
US7850621B2 (en) 2003-06-06 2010-12-14 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
US20050123507A1 (en) * 2003-06-30 2005-06-09 Mahmoud Ameri Formulations for coated microprojections having controlled solubility
EP1638523B8 (en) * 2003-06-30 2013-12-25 ALZA Corporation Formulations for coated microprojections containing non-volatile counterions
EP1502613A1 (en) 2003-08-01 2005-02-02 Novo Nordisk A/S Needle device with retraction means
WO2005033659A2 (en) 2003-09-29 2005-04-14 Pelikan Technologies, Inc. Method and apparatus for an improved sample capture device
US9351680B2 (en) 2003-10-14 2016-05-31 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a variable user interface
BRPI0415466A (pt) * 2003-10-24 2006-12-19 Alza Corp método e sistema de pré-tratamento para intensificar a distribuição transdérmica de fármacos
CN1897882A (zh) * 2003-10-28 2007-01-17 阿尔扎公司 降低烟草使用频率的方法和装置
JP4682144B2 (ja) 2003-10-31 2011-05-11 アルザ・コーポレーシヨン 微小突起列のための自己−作動性アプリケーター
WO2005065765A1 (en) * 2003-12-29 2005-07-21 3M Innovative Properties Company Medical devices and kits including same
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
EP1706026B1 (en) 2003-12-31 2017-03-01 Sanofi-Aventis Deutschland GmbH Method and apparatus for improving fluidic flow and sample capture
GB0402131D0 (en) 2004-01-30 2004-03-03 Isis Innovation Delivery method
AU2005228145B2 (en) 2004-03-24 2011-03-03 Corium Pharma Solutions, Inc. Transdermal delivery device
KR101114710B1 (ko) 2004-03-26 2012-02-29 우노메디컬 에이/에스 주사세트
WO2005094920A1 (en) 2004-03-30 2005-10-13 Novo Nordisk A/S Actuator system comprising lever mechanism
AU2005235990A1 (en) * 2004-04-13 2005-11-03 Alza Corporation Apparatus and method for transdermal delivery of multiple vaccines
JP5007427B2 (ja) * 2004-05-13 2012-08-22 アルザ コーポレイション 副甲状腺ホルモン剤の経皮送達のための装置および方法
US7591806B2 (en) * 2004-05-18 2009-09-22 Bai Xu High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances
EP1751546A2 (en) 2004-05-20 2007-02-14 Albatros Technologies GmbH & Co. KG Printable hydrogel for biosensors
WO2005120365A1 (en) 2004-06-03 2005-12-22 Pelikan Technologies, Inc. Method and apparatus for a fluid sampling device
US9775553B2 (en) 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
EP1773444B1 (en) * 2004-06-10 2017-09-20 3M Innovative Properties Company Patch application device and kit
US8062250B2 (en) 2004-08-10 2011-11-22 Unomedical A/S Cannula device
TW200616660A (en) * 2004-08-11 2006-06-01 Alza Corp Apparatus and method for transdermal delivery of natriuretic peptides
AR054309A1 (es) * 2004-09-08 2007-06-20 Alza Corp Disposicion de microproyecciones con mejor adhesion cutanea y distensibilidad
AU2005306429B2 (en) 2004-11-18 2011-04-14 3M Innovative Properties Company Microneedle array applicator and retainer
CN101060883B (zh) 2004-11-18 2010-06-23 3M创新有限公司 低轮廓微针阵列施放器
US20090054811A1 (en) * 2004-12-30 2009-02-26 Dirk Boecker Method and apparatus for analyte measurement test time
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
WO2006077262A1 (en) 2005-01-24 2006-07-27 Novo Nordisk A/S Medical device with protected transcutaneous device
US7985199B2 (en) 2005-03-17 2011-07-26 Unomedical A/S Gateway system
JP5301985B2 (ja) 2005-04-07 2013-09-25 スリーエム イノベイティブ プロパティズ カンパニー ツールフィードバック感知のためのシステム及び方法
US8043250B2 (en) * 2005-05-18 2011-10-25 Nanomed Devices, Inc. High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances
US8048017B2 (en) * 2005-05-18 2011-11-01 Bai Xu High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances
WO2007002523A2 (en) * 2005-06-24 2007-01-04 3M Innovative Properties Company Collapsible patch with microneedle array
EP2474338B1 (en) * 2005-06-27 2013-07-24 3M Innovative Properties Company Microneedle array applicator device
DE602005023458D1 (de) * 2005-09-12 2010-10-21 Unomedical As Einfürungssystem für ein Infusionsset mit einem ersten und zweiten Federeinheit
EP1924364A1 (en) * 2005-09-12 2008-05-28 Alza Corporation Coatable transdermal delivery microprojection assembly
DE602006007041D1 (de) 2005-12-23 2009-07-09 Unomedical As Injektionsvorrichtung
EP1988958B2 (en) 2006-02-28 2016-03-16 Unomedical A/S Inserter for infusion part
JP2009529930A (ja) * 2006-03-13 2009-08-27 ノボ・ノルデイスク・エー／エス 二目的通信手段を備えた医療システム
WO2007104755A1 (en) * 2006-03-13 2007-09-20 Novo Nordisk A/S Secure pairing of electronic devices using dual means of communication
EP2001453A4 (en) * 2006-03-15 2012-09-12 Alza Corp APPARATUS AND METHOD FOR TRANSDERMAL DELIVERY OF PARATHYROID HORMONE AGENTS FOR TREATING OR PREVENTING OSTEOPENIA
WO2007124411A1 (en) * 2006-04-20 2007-11-01 3M Innovative Properties Company Device for applying a microneedle array
US20070293816A1 (en) * 2006-04-25 2007-12-20 Alza Corporation Microprojection Array Application with Grouped Microprojections for High Drug Loading
WO2007127815A2 (en) * 2006-04-25 2007-11-08 Alza Corporation Microprojection array application with multilayered microprojection member for high drug loading
JP2009539444A (ja) 2006-06-06 2009-11-19 ノボ・ノルデイスク・エー／エス 皮膚に取付け可能な装置及び同装置のパッケージを含むアセンブリ
WO2007140783A2 (en) 2006-06-07 2007-12-13 Unomedical A/S Inserter for transcutaneous sensor
WO2007140785A1 (en) 2006-06-09 2007-12-13 Unomedical A/S Mounting pad
JP2009545341A (ja) * 2006-08-02 2009-12-24 ウノメディカル アクティーゼルスカブ カニューレ及び送出デバイス
CA2659077A1 (en) * 2006-08-02 2008-02-07 Unomedical A/S Insertion device
EP1917990A1 (en) 2006-10-31 2008-05-07 Unomedical A/S Infusion set
WO2008053481A1 (en) * 2006-11-01 2008-05-08 Svip 6 Llc Microneedle arrays
US20080214987A1 (en) * 2006-12-22 2008-09-04 Nanomed Devices, Inc. Microdevice And Method For Transdermal Delivery And Sampling Of Active Substances
US10525246B2 (en) 2006-12-22 2020-01-07 Nanomed Skincare, Inc. Microdevice and method for transdermal delivery and sampling of active substances
EP2121111B1 (en) 2007-01-22 2018-03-14 Corium International, Inc. Applicators for microneedle arrays
KR20090117749A (ko) * 2007-02-02 2009-11-12 우노메디컬 에이/에스 약물 공급장치
US20100140125A1 (en) * 2007-02-02 2010-06-10 Orla Mathiasen Injection Site for Injecting Medication
US9114238B2 (en) 2007-04-16 2015-08-25 Corium International, Inc. Solvent-cast microprotrusion arrays containing active ingredient
MX2009013207A (es) 2007-06-20 2010-01-25 Unomedical As Un cateter y un metodo y un aparato para fabricar tal cateter.
US8430850B2 (en) 2007-07-03 2013-04-30 Unomedical A/S Inserter having bistable equilibrium states
ES2360842T3 (es) 2007-07-10 2011-06-09 Unomedical A/S Dispositivo de inserción con dos muelles.
CA2694952A1 (en) 2007-07-18 2009-01-22 Unomedical A/S Insertion device with pivoting action
CA2988753A1 (en) 2007-08-06 2009-02-12 Serenity Pharmaceuticals, Llc Methods and devices for desmopressin drug delivery
WO2009039013A1 (en) * 2007-09-17 2009-03-26 Icu Medical, Inc. Insertion devices for infusion devices
GB0719577D0 (en) * 2007-10-08 2007-11-14 Kirby Andrew J Microimplant devices and methods of making and use thereof
WO2009048607A1 (en) 2007-10-10 2009-04-16 Corium International, Inc. Vaccine delivery via microneedle arrays
JP5178132B2 (ja) * 2007-10-11 2013-04-10 キヤノン株式会社 画像処理システム並びに画像処理方法
EP2209500B1 (en) 2007-10-31 2015-07-22 Novo Nordisk A/S Non-porous material as sterilization barrier
EP2231257A4 (en) 2007-12-24 2013-11-06 Univ Queensland APPLICATION METHOD
EP2247527A4 (en) 2008-02-07 2014-10-29 Univ Queensland PATCH PRODUCTION
AU2009214047A1 (en) 2008-02-13 2009-08-20 Unomedical A/S Sealing between a cannula part and a fluid path
EP2259816B1 (en) 2008-02-20 2015-10-21 Unomedical A/S Insertion device with horizontally moving part
WO2009126900A1 (en) 2008-04-11 2009-10-15 Pelikan Technologies, Inc. Method and apparatus for analyte detecting device
US11963995B2 (en) 2008-05-21 2024-04-23 Ferring B.V. Methods comprising desmopressin
US20100286045A1 (en) 2008-05-21 2010-11-11 Bjarke Mirner Klein Methods comprising desmopressin
ES2462465T5 (es) * 2008-05-21 2018-02-28 Ferring B.V. Desmopresina bucodispersable para aumentar el periodo inicial del sueño no alterado por nocturia
WO2009140735A1 (en) 2008-05-23 2009-11-26 The University Of Queensland Analyte detection by microneedle patch with analyte selective reagents.
WO2009149308A2 (en) * 2008-06-04 2009-12-10 Seventh Sense Biosystems, Inc. Compositions and methods for rapid one-step diagnosis
CA2727015A1 (en) * 2008-06-04 2009-12-10 Coda Therapeutics, Inc. Treatment of pain with gap junction modulation compounds
BRPI0922629A2 (pt) 2008-12-02 2016-01-05 Allergan Inc dispositivo de injeção
BRPI0923489A2 (pt) 2008-12-22 2016-01-26 Unomedical As dispositivo médico compreendendo almofada adesiva
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
US9113836B2 (en) 2009-03-02 2015-08-25 Seventh Sense Biosystems, Inc. Devices and techniques associated with diagnostics, therapies, and other applications, including skin-associated applications
WO2012018486A2 (en) 2010-07-26 2012-02-09 Seventh Sense Biosystems, Inc. Rapid delivery and/or receiving of fluids
US20110172508A1 (en) * 2010-01-13 2011-07-14 Seventh Sense Biosystems, Inc. Sampling device interfaces
US20110105872A1 (en) * 2009-10-30 2011-05-05 Seventh Sense Biosystems, Inc. Systems and methods for application to skin and control of actuation, delivery, and/or perception thereof
KR101030752B1 (ko) * 2009-04-09 2011-04-26 한국생명공학연구원 유체전달을 조절할 수 있는 마이크로 니들 유닛
CN102481440B (zh) * 2009-04-23 2014-06-25 新加坡国立大学 包括纳米级突起的装置及其制造方法
WO2010124255A2 (en) * 2009-04-24 2010-10-28 Corium International, Inc. Methods for manufacturing microprojection arrays
EP2424611A4 (en) * 2009-05-01 2012-10-24 Nanbu Plastics Co Ltd DEVICE FOR TRANSDERMAL ADMINISTRATIONS
US9108026B2 (en) * 2009-07-09 2015-08-18 Cook Medical Technologies Llc Spring action medical device
AU2010277755A1 (en) 2009-07-30 2012-02-02 Unomedical A/S Inserter device with horizontal moving part
ES2661063T3 (es) 2009-07-31 2018-03-27 3M Innovative Properties Company Matrices de micro agujas huecas
CN102548598B (zh) 2009-08-07 2014-09-17 犹诺医药有限公司 具有传感器和一个或多个插管的传送装置
CA2780294C (en) 2009-11-09 2018-01-16 Spotlight Technology Partners Llc Polysaccharide based hydrogels
CA2780274C (en) 2009-11-09 2018-06-26 Spotlight Technology Partners Llc Fragmented hydrogels
WO2011065972A2 (en) * 2009-11-24 2011-06-03 Seventh Sense Biosystems, Inc. Patient-enacted sampling technique
US20110172638A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Drug delivery device including multi-functional cover
WO2011088214A2 (en) * 2010-01-13 2011-07-21 Seventh Sense Biosystems, Inc. Rapid delivery and/or withdrawal of fluids
WO2011094573A1 (en) 2010-01-28 2011-08-04 Seventh Sense Biosystems, Inc. Monitoring or feedback systems and methods
US8911422B2 (en) 2010-02-24 2014-12-16 Hisamitsu Pharmaceutical Co., Inc. Micro-needle device
WO2011121023A1 (en) 2010-03-30 2011-10-06 Unomedical A/S Medical device
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
JP6327852B2 (ja) 2010-05-04 2018-05-23 コリウム インターナショナル， インコーポレイテッド 微小突起アレイを使用した副甲状腺ホルモンの経皮送達のための方法及びデバイス
ES2734560T3 (es) 2010-05-04 2019-12-10 Corium Int Inc Aplicadores para microagujas
ME02474B (me) 2010-05-12 2017-02-20 Radius Health Inc Terapijski režimi
WO2011163347A2 (en) 2010-06-23 2011-12-29 Seventh Sense Biosystems, Inc. Sampling devices and methods involving relatively little pain
WO2012006677A1 (en) 2010-07-14 2012-01-19 The University Of Queensland Patch applying apparatus
EP2593014B1 (en) 2010-07-16 2015-11-04 Seventh Sense Biosystems, Inc. Low-pressure environment for fluid transfer devices
WO2012021801A2 (en) 2010-08-13 2012-02-16 Seventh Sense Biosystems, Inc. Systems and techniques for monitoring subjects
EP2433663A1 (en) 2010-09-27 2012-03-28 Unomedical A/S Insertion system
US9133182B2 (en) 2010-09-28 2015-09-15 Radius Health, Inc. Selective androgen receptor modulators
EP2436412A1 (en) 2010-10-04 2012-04-04 Unomedical A/S A sprinkler cannula
EP2626107B1 (en) * 2010-10-07 2021-05-26 Hisamitsu Pharmaceutical Co., Inc. Applicator
WO2012061556A1 (en) 2010-11-03 2012-05-10 Flugen, Inc. Wearable drug delivery device having spring drive and sliding actuation mechanism
US9017289B2 (en) * 2010-11-03 2015-04-28 Covidien Lp Transdermal fluid delivery device
JP2012100783A (ja) * 2010-11-08 2012-05-31 Nanbu Plastics Co Ltd 薬液供給装置
CN103370007B (zh) 2010-11-09 2018-12-18 第七感生物系统有限公司 用于采血的系统和界面
JP2013544600A (ja) * 2010-11-23 2013-12-19 プレサージュ バイオサイエンシズ，インコーポレイテッド 固体デリバリーのための治療方法および組成物
US8814831B2 (en) * 2010-11-30 2014-08-26 Becton, Dickinson And Company Ballistic microneedle infusion device
EP2460553A1 (fr) * 2010-12-02 2012-06-06 Debiotech S.A. Dispositif pour l'insertion d'aiguilles
WO2012088154A1 (en) 2010-12-22 2012-06-28 Valeritas, Inc. Microneedle patch applicator
MX2013012349A (es) 2011-04-22 2014-07-09 Radius Health Inc Metodo para suministro de farmaco para pth, pthrp y peptidos relacionados.
EP2701600B1 (en) 2011-04-29 2016-06-08 Seventh Sense Biosystems, Inc. Delivering and/or receiving fluids
KR20140034200A (ko) 2011-04-29 2014-03-19 세븐쓰 센스 바이오시스템즈, 인크. 혈액 스폿들 또는 다른 신체 유체들을 수집 및/또는 조작하기 위한 시스템들 및 방법들
US20130158468A1 (en) 2011-12-19 2013-06-20 Seventh Sense Biosystems, Inc. Delivering and/or receiving material with respect to a subject surface
WO2012149155A1 (en) 2011-04-29 2012-11-01 Seventh Sense Biosystems, Inc. Systems and methods for collecting fluid from a subject
US20140207101A1 (en) * 2011-06-09 2014-07-24 3M Innovative Properties Company Microstructure device with removable microstructure patch
KR101973824B1 (ko) 2011-07-27 2019-04-29 히사미쓰 세이야꾸 가부시키가이샤 어플리케이터
CN103764197B (zh) 2011-09-07 2017-03-15 3M创新有限公司 用于中空微针阵列的递送系统
NL2007461C2 (en) * 2011-09-23 2013-03-26 Ambro B V System for transporting fluid across or into a biological barrier, device and capsule as part of the system.
US11197689B2 (en) 2011-10-05 2021-12-14 Unomedical A/S Inserter for simultaneous insertion of multiple transcutaneous parts
EP2764887B1 (en) * 2011-10-06 2020-12-02 Hisamitsu Pharmaceutical Co., Inc. Applicator
US11179553B2 (en) 2011-10-12 2021-11-23 Vaxxas Pty Limited Delivery device
KR102022574B1 (ko) * 2011-10-12 2019-09-18 쓰리엠 이노베이티브 프로퍼티즈 컴파니 통합된 마이크로니들 어레이 전달 시스템
CN103857423B (zh) * 2011-10-12 2016-09-07 3M创新有限公司 一体的微针阵列递送系统
EP2583715A1 (en) 2011-10-19 2013-04-24 Unomedical A/S Infusion tube system and method for manufacture
US9440051B2 (en) 2011-10-27 2016-09-13 Unomedical A/S Inserter for a multiplicity of subcutaneous parts
EP2771043A4 (en) 2011-10-28 2015-04-29 Presage Biosciences Inc METHODS OF DRUG DELIVERY
DE102011119055B4 (de) * 2011-11-16 2013-08-14 Lts Lohmann Therapie-Systeme Ag Zylinder-Kolben-Einheit mit Klebescheibe II
ES2761255T3 (es) * 2012-04-05 2020-05-19 Hisamitsu Pharmaceutical Co Dispositivo de punción
DE202012006290U1 (de) * 2012-06-29 2013-09-30 Lukas Pregenzer Inkontinenzimplantat
JP6091818B2 (ja) * 2012-08-28 2017-03-08 コスメディ製薬株式会社 マイクロニードルパッチ投与装置
WO2014058746A1 (en) * 2012-10-10 2014-04-17 3M Innovative Properties Company Force-controlled applicator for applying a microneedle device to skin
AU2013364053B2 (en) 2012-12-21 2018-08-30 Corium Pharma Solutions, Inc. Microarray for delivery of therapeutic agent and methods of use
CN104902943B (zh) * 2013-01-08 2017-10-31 3M创新有限公司 用于向皮肤施用微针装置的施用装置
BR122020006959B1 (pt) * 2013-03-12 2022-04-26 Corium, Inc Aplicador de microprojeções
CA2903459C (en) * 2013-03-15 2024-02-20 Corium International, Inc. Multiple impact microprojection applicators and methods of use
EP2968119B1 (en) 2013-03-15 2019-09-18 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
BR112015022625B1 (pt) 2013-03-15 2023-01-31 Corium, Inc Aparelho de microestrutura para entrega de agente terapêutico
JP2016514133A (ja) 2013-03-15 2016-05-19 コリウム インターナショナル， インコーポレイテッド ポリマーを含まない微細構造物を含むマイクロアレイ、製造方法および使用方法
US20140350516A1 (en) 2013-05-23 2014-11-27 Allergan, Inc. Mechanical syringe accessory
US20140350518A1 (en) 2013-05-23 2014-11-27 Allergan, Inc. Syringe extrusion accessory
CN105246541B (zh) 2013-05-31 2018-01-16 3M创新有限公司 包括双覆盖件的微针注射设备
PL3003459T3 (pl) 2013-05-31 2018-11-30 3M Innovative Properties Company Mikroigłowy aparat iniekcyjny zawierający odwrócony element wykonawczy
SG11201509810TA (en) 2013-05-31 2015-12-30 3M Innovative Properties Co Microneedle injection and infusion apparatus and method of using same
EP3027263A1 (en) 2013-07-30 2016-06-08 ZP Opco, Inc. Low-profile microneedle patch applicator
AU2013400841B2 (en) * 2013-09-18 2018-12-13 Cosmed Pharmaceutical Co., Ltd. Microneedle patch application device and patch holder
DE102013021058B4 (de) * 2013-12-18 2017-10-12 Gerresheimer Regensburg Gmbh Vorrichtung zur Applizierung eines Nadelarrays auf biologischem Gewebe
GB201401133D0 (en) 2014-01-23 2014-03-12 Renephra Ltd Fluid extraction device, applicator device and associated methods
CN106061546A (zh) * 2014-02-10 2016-10-26 Lts勒曼治疗系统股份公司 微针系统及其制造方法
US10029048B2 (en) 2014-05-13 2018-07-24 Allergan, Inc. High force injection devices
US20160038434A1 (en) * 2014-08-01 2016-02-11 Innovative Drive Corporation Device and method for application of a transdermal membrane
EP3188714A1 (en) 2014-09-04 2017-07-12 Corium International, Inc. Microstructure array, methods of making, and methods of use
US10226585B2 (en) 2014-10-01 2019-03-12 Allergan, Inc. Devices for injection and dosing
CA2975275C (en) 2015-02-02 2023-08-29 Vaxxas Pty Limited Microprojection array applicator and method
CA2976544A1 (en) 2015-03-10 2016-09-15 Allergan Pharmaceuticals Holdings (Ireland) Unlimited Company Multiple needle injector
RU2737496C2 (ru) 2015-04-29 2020-12-01 Радиус Фармасьютикалз, Инк. Способы лечения рака
WO2017004067A1 (en) 2015-06-29 2017-01-05 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
JP2017023404A (ja) 2015-07-22 2017-02-02 日本写真印刷株式会社 マイクロニードルパッチ用インパクト付加型アプリケータ及び先端部材
US11103259B2 (en) 2015-09-18 2021-08-31 Vaxxas Pty Limited Microprojection arrays with microprojections having large surface area profiles
EP3355981A4 (en) 2015-09-28 2019-05-22 Vaxxas Pty Limited MICROPROJECTION ARRANGEMENTS WITH IMPROVED SKIN-IMPROPER PROPERTIES AND METHOD THEREFOR
EP3395397B1 (en) * 2015-12-21 2022-10-12 Medrx Co., Ltd. Microneedle patch applicator housing
WO2017143345A1 (en) 2016-02-19 2017-08-24 Zp Opco, Inc. Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines
KR102377747B1 (ko) 2016-03-16 2022-03-23 코스메드 파마소티컬 씨오 쩜 엘티디 마이크로니들 패치 케이스
KR102232054B1 (ko) 2016-04-08 2021-03-26 알레간 인코포레이티드 흡인 및 주입 디바이스
CN105999259A (zh) * 2016-05-11 2016-10-12 长春海基亚生物技术股份有限公司 无针注射狂犬病疫苗系统与应用
US20200306518A1 (en) 2016-05-20 2020-10-01 Uprax Microsolutions B.V. System and method for applying microneedles
JP7221699B2 (ja) 2016-06-22 2023-02-14 エリプセス ファーマ エルティーディー Ａｒ＋乳癌の治療方法
AU2017378040B2 (en) 2016-12-16 2023-06-08 Vivasor, Inc. Application device for a fluid delivery apparatus and method of use
KR102297238B1 (ko) 2016-12-20 2021-09-01 히사미쓰 세이야꾸 가부시키가이샤 어플리케이터
FI3565542T3 (fi) 2017-01-05 2024-06-24 Radius Pharmaceuticals Inc Rad1901-2hcl:n polymorfisia muotoja
CN110167625B (zh) 2017-01-25 2023-03-03 考司美德制药株式会社 微针贴应用装置
USD867582S1 (en) 2017-03-24 2019-11-19 Allergan, Inc. Syringe device
JP6931217B2 (ja) 2017-03-28 2021-09-01 コスメディ製薬株式会社 水溶性シート状製剤のアプリケータ
EP4306803A3 (en) 2017-03-31 2024-04-10 Vaxxas Pty Limited Device and method for coating surfaces
JP2018191783A (ja) * 2017-05-15 2018-12-06 富士フイルム株式会社 マイクロニードルアレイユニット、および容器
US11175128B2 (en) 2017-06-13 2021-11-16 Vaxxas Pty Limited Quality control of substrate coatings
EP4218893A1 (en) 2017-08-04 2023-08-02 Vaxxas Pty Limited Compact high mechanical energy storage and low trigger force actuator for the delivery of microprojection array patches (map)
US10430138B2 (en) * 2017-08-10 2019-10-01 Canon Kabushiki Kaisha Communication apparatus
US11660264B2 (en) 2017-08-23 2023-05-30 Emergex USA Corporation Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches
CN111050749A (zh) 2017-08-23 2020-04-21 佐萨诺制药公司 快速实现佐米曲坦的治疗性浓度以用于治疗偏头痛和丛集性头痛的方法
EP3697490A4 (en) 2017-10-17 2021-09-08 3M Innovative Properties Company APPLICATOR FOR APPLYING A FIELD OF MICRONES ON THE SKIN
JP7033886B2 (ja) * 2017-11-07 2022-03-11 ニプロ株式会社 穿刺用器具
JP2019126733A (ja) 2018-01-24 2019-08-01 コスメディ製薬株式会社 マイクロニードル用緊迫器具
US11660265B2 (en) 2018-06-28 2023-05-30 Emergex USA Corporation Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches
US11643385B2 (en) 2018-07-04 2023-05-09 Radius Pharmaceuticals, Inc. Polymorphic forms of RAD1901-2HCl
KR20210086599A (ko) * 2018-08-30 2021-07-08 니프로 가부시키가이샤 마이크로 니들 어플리케이터
JP7099189B2 (ja) * 2018-08-30 2022-07-12 ニプロ株式会社 マイクロニードルアプリケータ
JP7172293B2 (ja) * 2018-08-30 2022-11-16 ニプロ株式会社 マイクロニードルアプリケータ
US11246997B2 (en) * 2018-09-25 2022-02-15 Palo Alto Research Center Incorporated Handheld filament extension atomizer for precision delivery of drugs and therapeutics
CN109364364B (zh) * 2018-12-10 2021-06-22 徐爱梅 一种皮肤科涂药装置
JP7491551B2 (ja) 2019-04-25 2024-05-28 コスメディ製薬株式会社 水溶性シート状製剤のアプリケータ２
US11801068B2 (en) 2019-06-25 2023-10-31 William Ma Sheathed cutting device
CN111685867B (zh) * 2020-06-22 2020-12-01 镇江恒生涓恩医疗器械有限公司 一种多级稳定型消融电极
EP3974017A1 (en) * 2020-09-28 2022-03-30 Latch Medical A microneedle patch application system
CN114748778B (zh) * 2021-01-11 2024-05-03 苏州纳生微电子有限公司 传动结构、应用传动结构的给液装置及其使用方法
US11654270B2 (en) 2021-09-28 2023-05-23 Biolinq Incorporated Microneedle enclosure and applicator device for microneedle array based continuous analyte monitoring device
USD1033641S1 (en) 2021-12-17 2024-07-02 Biolinq Incorporated Microneedle array sensor applicator device
WO2024097385A1 (en) * 2022-11-05 2024-05-10 Kindeva Drug Delivery L.P. Microneedle array applicator and system

Family Cites Families (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE25637E (en) 1964-09-08 Means for vaccinating
US3136314A (en) 1960-08-01 1964-06-09 Kravitz Harvey Vaccinating devices
US3964482A (en) 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
BE795384A (fr) 1972-02-14 1973-08-13 Ici Ltd Pansements
OA05448A (fr) 1975-10-16 1981-03-31 Manufrance Manufacture Francai Dispositif vaccinateur multipénétrant.
GB2064329B (en) * 1979-11-01 1983-06-22 Matburn Holdings Ltd Multiple puncture apparatus
FR2474856A1 (fr) 1980-01-31 1981-08-07 Merieux Inst Dispositif scarificateur
US4535769A (en) * 1981-03-23 1985-08-20 Becton, Dickinson And Company Automatic retractable lancet assembly
EP0429842B1 (en) 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Device for the transdermal administration of protein or peptide drug
US5279544A (en) 1990-12-13 1994-01-18 Sil Medics Ltd. Transdermal or interdermal drug delivery devices
FR2696334B1 (fr) * 1992-10-01 1994-12-02 Boudjema J Pascal Dispositif pour transplantation de greffons capillaires de petit diamètre.
US5439473A (en) * 1993-12-13 1995-08-08 Modulohm A/S Safety lancet
US5350392A (en) * 1994-02-03 1994-09-27 Miles Inc. Lancing device with automatic cocking
US5487726A (en) 1994-06-16 1996-01-30 Ryder International Corporation Vaccine applicator system
ATE177325T1 (de) 1994-12-09 1999-03-15 Novartis Erfind Verwalt Gmbh Transdermales system
AU5740496A (en) 1995-05-22 1996-12-11 General Hospital Corporation, The Micromechanical device and method for enhancing delivery of compounds through the skin
WO1996037256A1 (en) 1995-05-22 1996-11-28 Silicon Microdevices, Inc. Micromechanical patch for enhancing the delivery of compounds through the skin
DE19525607A1 (de) 1995-07-14 1997-01-16 Boehringer Ingelheim Kg Transcorneales Arzneimittelfreigabesystem
IL124510A0 (en) 1996-05-17 1998-12-06 Mercury Diagnostics Inc Disposable element for use in a body fluid sampling device
ZA975326B (en) 1996-06-18 1998-01-14 Alza Corp Device and method for enhancing transdermal flux of agents being delivered or sampled.
ES2200187T3 (es) 1996-07-03 2004-03-01 Altea Therapeutics Corporation Microporacion mecanica multiple de la piel o de la mucosa.
CA2265906C (en) 1996-09-17 2003-11-11 Deka Products Limited Partnership System for delivery of drugs by transport
ES2195190T3 (es) 1996-12-20 2003-12-01 Alza Corp Dispositivo y metodo para mejorar el flujo de agente transdermico.
DE19654391A1 (de) 1996-12-27 1998-07-02 Basf Ag Katalysator zur selektiven Herstellung von Propylen aus Propan
BR9714113A (pt) 1996-12-31 2000-03-21 Shell Int Research Plataforma de tirante
US5964718A (en) * 1997-11-21 1999-10-12 Mercury Diagnostics, Inc. Body fluid sampling device
US6918901B1 (en) 1997-12-10 2005-07-19 Felix Theeuwes Device and method for enhancing transdermal agent flux
CA2313698C (en) 1997-12-11 2008-04-15 Alza Corporation Device for enhancing transdermal agent flux
ATE406935T1 (de) 1997-12-11 2008-09-15 Alza Corp Vorrichtung zur verbesserung des transdermalen flusses von medikamenten
KR100572539B1 (ko) 1997-12-11 2006-04-24 알자 코포레이션 경피성 작용제 유동률을 증진시키기 위한 장치
EP1086214B1 (en) 1998-06-10 2009-11-25 Georgia Tech Research Corporation Microneedle devices and methods of their manufacture
US6743211B1 (en) * 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6611707B1 (en) * 1999-06-04 2003-08-26 Georgia Tech Research Corporation Microneedle drug delivery device
US6835184B1 (en) * 1999-09-24 2004-12-28 Becton, Dickinson And Company Method and device for abrading skin
US6248120B1 (en) * 2000-01-10 2001-06-19 P. Z. “HTL” Spolka Akcyjna Puncturing device
US6537242B1 (en) * 2000-06-06 2003-03-25 Becton, Dickinson And Company Method and apparatus for enhancing penetration of a member for the intradermal sampling or administration of a substance
US6533949B1 (en) * 2000-08-28 2003-03-18 Nanopass Ltd. Microneedle structure and production method therefor
US7419481B2 (en) 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
AU9682801A (en) * 2000-10-13 2002-04-22 Alza Corp Apparatus and method for piercing skin with microprotrusions
IL155375A0 (en) 2000-10-13 2003-11-23 Alza Corp Microblade array impact applicator
HUP0303576A2 (en) 2000-10-13 2004-01-28 Alza Corp Microprotrusion member retainer for impact applicator
HUP0302924A2 (en) * 2000-10-26 2003-12-29 Alza Corp Transdermal drug delivery devices having coated microprotrusions
US6855372B2 (en) 2001-03-16 2005-02-15 Alza Corporation Method and apparatus for coating skin piercing microprojections
CN100349632C (zh) 2001-04-20 2007-11-21 阿尔扎公司 具有包含有益药剂的涂层的微小突出物阵列
US7429258B2 (en) * 2001-10-26 2008-09-30 Massachusetts Institute Of Technology Microneedle transport device
US20030199810A1 (en) 2001-11-30 2003-10-23 Trautman Joseph Creagan Methods and apparatuses for forming microprojection arrays
HUP0402605A2 (hu) 2001-12-20 2005-06-28 Alza Corporation Eszköz mikroszkopikus bemetszések ejtésére állat bőrszövetén
AU2003209645A1 (en) * 2002-03-04 2003-09-16 Nano Pass Technologies Ltd. Devices and methods for transporting fluid across a biological barrier
US6945952B2 (en) * 2002-06-25 2005-09-20 Theraject, Inc. Solid solution perforator for drug delivery and other applications
AU2003279641B2 (en) 2002-06-28 2009-06-18 Alza Corporation Transdermal drug delivery devices having coated microprotrusions
CN102872526A (zh) * 2002-07-19 2013-01-16 3M创新有限公司 微针装置和微针施用设备
AR042815A1 (es) 2002-12-26 2005-07-06 Alza Corp Dispositivo de suministro de agente activo que tiene miembros compuestos
EP1638523B8 (en) 2003-06-30 2013-12-25 ALZA Corporation Formulations for coated microprojections containing non-volatile counterions
US20050123507A1 (en) 2003-06-30 2005-06-09 Mahmoud Ameri Formulations for coated microprojections having controlled solubility
CN1897883A (zh) 2003-10-28 2007-01-17 阿尔扎公司 通过涂覆的微喷射体释放治疗用肽和蛋白的聚合物缀合物
JP4682144B2 (ja) 2003-10-31 2011-05-11 アルザ・コーポレーシヨン 微小突起列のための自己−作動性アプリケーター
WO2005051456A2 (en) 2003-11-13 2005-06-09 Alza Corporation Composition and apparatus for transdermal delivery
JP5007427B2 (ja) 2004-05-13 2012-08-22 アルザ コーポレイション 副甲状腺ホルモン剤の経皮送達のための装置および方法
CA2593112A1 (en) 2005-01-21 2006-07-27 Alza Corporation Therapeutic peptide formulations for coating microneedles with improved stability containing at least one counterion
CA2596075A1 (en) 2005-01-31 2006-08-10 Alza Corporation Coated microprojections having reduced variability and method for producing same
US20060204562A1 (en) 2005-02-16 2006-09-14 Cormier Michel J Microprojection arrays with improved biocompatibility
WO2006130826A1 (en) 2005-06-02 2006-12-07 Alza Corporation Method for terminal sterilization of transdermal delivery devices
EP1898989A2 (en) 2005-06-21 2008-03-19 Alza Corporation Method and device for coating a continuous strip of microprojection members

Also Published As

Publication number Publication date
US20050096586A1 (en) 2005-05-05
EP1680154A2 (en) 2006-07-19
AU2004287414B2 (en) 2010-11-25
CN1901840A (zh) 2007-01-24
WO2005044333A2 (en) 2005-05-19
TW200633675A (en) 2006-10-01
US7097631B2 (en) 2006-08-29
KR20060099523A (ko) 2006-09-19
US9421351B2 (en) 2016-08-23
WO2005044333A3 (en) 2006-06-01
BRPI0415629A (pt) 2006-12-12
ATE539687T1 (de) 2012-01-15
EP1680154B1 (en) 2012-01-04
JP4682144B2 (ja) 2011-05-11
AU2004287414A1 (en) 2005-05-19
CA2543641A1 (en) 2005-05-19
US20070027427A1 (en) 2007-02-01
ES2377647T3 (es) 2012-03-29
CN100571643C (zh) 2009-12-23
JP2007509706A (ja) 2007-04-19
EP1680154A4 (en) 2007-07-18

Similar Documents

Publication Publication Date Title
AR046696A1 (es) Aplicador auto-accionante para grupo de microproyecciones
AR047229A1 (es) Administracion de conjugados polimericos de peptidos y proteinas terapeuticos por medio de microproyecciones revestidas
AR046697A1 (es) Metodo y sistema de administracion transdermica de agente asistido por frecuencia
AR046307A1 (es) Metodo de pretratamiento y sistema para mejorar la administracion transdermica de drogas
AR040819A1 (es) Dispositivo de administracion transdermica de vacuna que tiene microproyecciones revestidas
CN102657914B (zh) 高渗透效率的微针透皮输入贴
AR047112A1 (es) Composiciones de adn estabilizado para recubrir microproyecciones
BRPI0517501A (pt) dispositivo médico apropriado para uso na administração de um componente ativo na ou através da pele
AR048862A1 (es) Aparatos y metodos para el suministro transdermico de una vacuna antigripal
AR048827A1 (es) Aparato y metodo para la administracion transdermica de agentes basados en fentanil
MX349176B (es) Suministro transdermico de farmaco empleando un osmolito y un agente vasoactivo.
BRPI0416132A (pt) sistema e método para liberação de vacina transdérmica
KR20180011826A (ko) 무고통 및 무패치의 슈팅 마이크로구조체
ATE471144T1 (de) Intranasale verabreichung von schnell wirkendem insulin
AR046824A1 (es) Composicion y aparato para la administracion transdermica.
BRPI0413539B8 (pt) dispositivo para distribuir medicamento para o corpo de um paciente por injeção
BR0213245A (pt) Dispositivo e sonda para a aplicação ocular de um princìpio ativo
UY28398A1 (es) Método y parche de inmunización por disposición de microproyección
AR046690A1 (es) Composiciones de adn estabilizado para recubrir microproyecciones
BR0208064A (pt) dispositivo médico, e, processo para injetar medicamento
BRPI0518460A2 (pt) mÉtodo para tratar emergÊncia alÉrgica em um paciente, dispositivo de distribuiÇço de droga contendo uma soluÇço de epinefrina, e, kit para tratar uma emergÊncia alÉrgia'
AR026986A1 (es) Implante farmaceutico con contenido de componentes de liberacion inmediata y liberacion sostenida y metodos de administracion
WO2004030743A3 (en) Drug delivery device having coated microprojections incorporating vasoconstrictors
CY1113575T1 (el) Χρηση συνθεσεων οπιοειδων σε συσκευες χορηγησης δραστικης ουσιας χωρις βελονα
UY27378A1 (es) Composición farmacéutica

Legal Events

Date Code Title Description
FA Abandonment or withdrawal