ME02474B - Terapijski režimi - Google Patents

Terapijski režimi

Info

Publication number
ME02474B
ME02474B MEP-2016-149A MEP14916A ME02474B ME 02474 B ME02474 B ME 02474B ME P14916 A MEP14916 A ME P14916A ME 02474 B ME02474 B ME 02474B
Authority
ME
Montenegro
Prior art keywords
dosage form
unit dosage
use according
compound
oral administration
Prior art date
Application number
MEP-2016-149A
Other languages
German (de)
English (en)
French (fr)
Inventor
Louis O'dea
C Richard Lyttle
Jonathan Guerriero
Original Assignee
Radius Health Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Radius Health Inc filed Critical Radius Health Inc
Publication of ME02474B publication Critical patent/ME02474B/me

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/485—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Reproductive Health (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Claims (10)

1.Jedinični dozni oblik koji obuhvata od 0,9 do 1,1 mg, od 2,2 do 2,8 mg, od 4,4 do 5,6 mg ili od 9 do 11mg jedinjenja formule I kao njegove dihidrohloridne soli za upotrebu u postupku tretiranja vazomotornih poremećaja u predmenopauznom ili postmenopauznom stanju žene kojoj je to potrebno, pri čemu postupak obuhvata davanje pacijentu jedanput dnevno pomenutog jediničnog doznog oblika.
2.Upotreba jedinjenja formule I kao njegove dihidrohloridne soli u proizvodnji leka za tretiranje vazomotornih poremećaja u predmenopauznom ili postmenopauznom stanju žene kojoj je to potrebno, pri čemu je lek jedinični dozni oblik koji obuhvata od 0,9 do 1,1 mg, od 2,2 do 2,8 mg, od 4,4 do 5,6 mg ili od 9 do 11 mg pomenutog jedinjenja, i gde postupak obuhvata davanje pacijentu jedanput dnevno pomenutog jediničnog doznog oblika.
3.Jedinični dozni oblik za upotrebu prema zahtevu 1, ili upotreba prema zahtevu 2, pri čemu jedinični dozni oblik obuhvata 1, 2,5 , 5 ili 10 mg jedinjenja formule I kao njegove dihidrohloridne soli.
4.Jedinični dozni oblik za upotrebu prema zahtevu 1, ili upotreba prema zahtevu 2, pri čemu jedinični dozni oblik obuhvata 10 mg jedinjenja formule I kao njegove dihidrohloridne soli.
5.Jedinični dozni oblik za upotrebu ili upotreba prema zahtevima 1 do 4, koji dalje obuhvata jedan ili više farmaceutski prihvatljivih ekscipijenata.
6.Jedinični dozni oblik prema zahtevu 5, pri čemu je jedinični dozni oblik tableta ili kapsula pogodna za oralnu primenu.
7.Jedinični dozni oblik prema zahtevu 6, pri čemu se nakon oralne primene jediničnog doznog oblika više od 50% rastvara u želucu pre nego što se oslobodi u tankim crevima.
8.Jedinični dozni oblik prema zahtevu 7, pri čemu jedinični dozni oblik nije obložen oblogom otpornom na kiseline.
9.Jedinični dozni oblik za upotrebu ili upotreba prema bilo kom od zahteva 1 do 4, pri čemu se jedinični dozni oblik primenjuje oralno, jedanput dnevno; i opciono pri čemu je jedinični dozni oblik tableta ili kapsula pogodna za oralnu primenu.
10.Jedinični dozni oblik za upotrebu ili upotreba prema zahtevu 9, pri čemu je jedinični dozni oblik tableta ili kapsula pogodna za oralnu primenu, a koja se više od 50% rastvara u želucu pre nego što se oslobodi u tankim crevima, a opciono pri čemu jedinični dozni oblik nije obložen oblogom otpornom na kiseline.
MEP-2016-149A 2010-05-12 2011-05-12 Terapijski režimi ME02474B (me)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33409510P 2010-05-12 2010-05-12
EP11781299.0A EP2568806B1 (en) 2010-05-12 2011-05-12 Therapeutic regimens
PCT/US2011/036311 WO2011143469A1 (en) 2010-05-12 2011-05-12 Therapeutic regimens

Publications (1)

Publication Number Publication Date
ME02474B true ME02474B (me) 2017-02-20

Family

ID=44914714

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-2016-149A ME02474B (me) 2010-05-12 2011-05-12 Terapijski režimi

Country Status (17)

Country Link
US (2) US20130053448A1 (me)
EP (2) EP3106159A1 (me)
CA (1) CA2799183A1 (me)
CY (1) CY1117893T1 (me)
DK (1) DK2568806T3 (me)
ES (1) ES2585884T3 (me)
HR (1) HRP20160929T1 (me)
HU (1) HUE030072T2 (me)
LT (1) LT2568806T (me)
ME (1) ME02474B (me)
MX (1) MX342898B (me)
PL (1) PL2568806T3 (me)
PT (1) PT2568806T (me)
RS (1) RS54993B1 (me)
SI (1) SI2568806T1 (me)
SM (1) SMT201600263B (me)
WO (1) WO2011143469A1 (me)

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PT2568806T (pt) 2010-05-12 2016-08-05 Radius Health Inc Regimes terapêuticos
ES2550319T3 (es) 2010-09-28 2015-11-06 Radius Health, Inc Moduladores selectivos del receptor de andrógenos
US9421264B2 (en) 2014-03-28 2016-08-23 Duke University Method of treating cancer using selective estrogen receptor modulators
RS67458B1 (sr) 2014-03-28 2025-12-31 Univ Duke Lečenje kancera dojke pozitivnog na receptor estrogena upotrebom selektivnih modulatora receptora estrogena
RS63311B1 (sr) 2016-06-22 2022-07-29 Ellipses Pharma Ltd Ar+ metode lečenja raka dojke
KR102881465B1 (ko) 2017-01-05 2025-11-04 래디어스 파마슈티컬스, 인코포레이티드 Rad1901-2hcl의 다형 형태
CN112423844B (zh) 2018-07-04 2024-08-13 雷迪厄斯制药公司 Rad1901-2hcl的多晶型形式
JOP20210218A1 (ar) 2019-02-12 2023-01-30 Radius Pharmaceuticals Inc عمليات ومركبات
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