AR048862A1 - Aparatos y metodos para el suministro transdermico de una vacuna antigripal - Google Patents
Aparatos y metodos para el suministro transdermico de una vacuna antigripalInfo
- Publication number
- AR048862A1 AR048862A1 ARP050101305A ARP050101305A AR048862A1 AR 048862 A1 AR048862 A1 AR 048862A1 AR P050101305 A ARP050101305 A AR P050101305A AR P050101305 A ARP050101305 A AR P050101305A AR 048862 A1 AR048862 A1 AR 048862A1
- Authority
- AR
- Argentina
- Prior art keywords
- vaccine
- antigripal
- appliances
- methods
- transdermal supply
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55583—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0023—Drug applicators using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0046—Solid microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0061—Methods for using microneedles
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16211—Influenzavirus B, i.e. influenza B virus
- C12N2760/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Pulmonology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Anesthesiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Medical Informatics (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Un aparato y un método para el suministro transdérmico de un agente activo desde el punto de vista inmunologico que comprende un sistema de suministro que presenta una pieza (o sistema) con microproyecciones que incluye numerosas microproyecciones ( o un arreglo de las mismas) que se adaptan para perforar a través del estrato corneo en la capa epidérmica subyacente, o en las capas epidérmica y dérmica; la pieza con microproyecciones presenta un recubrimiento biocompatible dispuesto en la misma que incluye el agente activo desde el punto de vista inmunologico. Preferentemente, el recubrimiento biocompatible se forma a partir de una formulacion de recubrimiento que es una vacuna.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US55915304P | 2004-04-01 | 2004-04-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR048862A1 true AR048862A1 (es) | 2006-06-07 |
Family
ID=35150502
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP050101305A AR048862A1 (es) | 2004-04-01 | 2005-04-01 | Aparatos y metodos para el suministro transdermico de una vacuna antigripal |
Country Status (12)
Country | Link |
---|---|
US (1) | US20050220854A1 (es) |
EP (1) | EP1734993A4 (es) |
JP (1) | JP2007530680A (es) |
KR (1) | KR20060135931A (es) |
CN (1) | CN101124343A (es) |
AR (1) | AR048862A1 (es) |
AU (1) | AU2005232541A1 (es) |
BR (1) | BRPI0509493A (es) |
CA (1) | CA2562932A1 (es) |
MX (1) | MXPA06011429A (es) |
TW (1) | TW200536573A (es) |
WO (1) | WO2005099751A2 (es) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020193729A1 (en) * | 2001-04-20 | 2002-12-19 | Cormier Michel J.N. | Microprojection array immunization patch and method |
US20050271684A1 (en) * | 2004-04-13 | 2005-12-08 | Trautman Joseph C | Apparatus and method for transdermal delivery of multiple vaccines |
CA2566759A1 (en) * | 2004-05-19 | 2005-11-24 | Alza Corporation | Method and formulation for transdermal delivery of immunologically active agents |
WO2006062637A2 (en) * | 2004-11-03 | 2006-06-15 | Novartis Vaccines And Diagnostics Inc. | Influenza vaccination |
GB0505518D0 (en) * | 2005-03-17 | 2005-04-27 | Chiron Srl | Combination vaccines with whole cell pertussis antigen |
AU2006336187A1 (en) * | 2005-12-28 | 2007-07-26 | Alza Corporation | Stable therapeutic formulations |
CA2702340C (en) | 2006-10-12 | 2014-12-16 | The University Of Queensland | Compositions and methods for modulating immune responses |
US8911749B2 (en) | 2007-04-16 | 2014-12-16 | Corium International, Inc. | Vaccine delivery via microneedle arrays |
CA2686093C (en) | 2007-04-16 | 2018-05-08 | Corium International, Inc. | Solvent-cast microneedle arrays containing active |
US8506966B2 (en) | 2008-02-22 | 2013-08-13 | Novartis Ag | Adjuvanted influenza vaccines for pediatric use |
WO2010001671A1 (ja) | 2008-06-30 | 2010-01-07 | 久光製薬株式会社 | マイクロニードルデバイスおよびマイクロニードルデバイスによるインフルエンザワクチンの奏功性を上昇させる方法 |
JP5744517B2 (ja) * | 2008-07-30 | 2015-07-08 | 久光製薬株式会社 | マイクロニードルデバイスおよびマイクロニードルデバイスによる日本脳炎ウイルス抗原の奏功性を上昇させる方法 |
SG173160A1 (en) | 2009-01-30 | 2011-08-29 | Hisamitsu Pharmaceutical Co | Microneedle device |
EP3173097A3 (en) | 2009-02-10 | 2017-07-12 | Seqirus UK Limited | Influenza vaccines with reduced amounts of squalene |
WO2011011390A1 (en) * | 2009-07-20 | 2011-01-27 | Novavax, Inc. | Purified recombinant influenza virus ha proteins |
WO2011090712A2 (en) * | 2009-12-28 | 2011-07-28 | Ligocyte Pharmaceuticals, Inc. | Methods for stabilizing influenza antigen enveloped virus-based virus-like particle solutions |
EP2566501B1 (en) | 2010-05-04 | 2019-03-13 | Corium International, Inc. | Method and device for transdermal delivery of parathyroid hormone using a microprojection array |
WO2011151726A2 (en) * | 2010-06-01 | 2011-12-08 | Novartis Ag | Concentration of vaccine antigens with lyophilization |
DK2575872T3 (da) * | 2010-06-01 | 2020-10-19 | Seqirus Uk Ltd | Koncentrering af influenzavaccineantigener uden frysetørring |
WO2013029033A2 (en) * | 2011-08-25 | 2013-02-28 | Brian Pulliam | Rotavirus preparations with excess calcium ions and high viscosities that ensure vaccine viability at elevated temperatures |
CN102703587B (zh) * | 2012-05-18 | 2013-11-27 | 中国疾病预防控制中心传染病预防控制所 | 用于检测莱姆病螺旋体的环介导等温扩增法 |
KR102265808B1 (ko) | 2012-12-21 | 2021-06-16 | 코리움, 인크. | 치료제의 전달을 위한 마이크로어레이 및 그것의 사용방법 |
AU2014249471B2 (en) | 2013-03-12 | 2019-01-24 | Corium Pharma Solutions, Inc. | Microprojection applicators |
AU2014237279B2 (en) | 2013-03-15 | 2018-11-22 | Corium Pharma Solutions, Inc. | Microarray with polymer-free microstructures, methods of making, and methods of use |
WO2014150285A2 (en) | 2013-03-15 | 2014-09-25 | Corium International, Inc. | Multiple impact microprojection applicators and methods of use |
CA2906541C (en) | 2013-03-15 | 2022-06-21 | Corium International, Inc. | Microarray for delivery of therapeutic agent and methods of use |
WO2015009853A1 (en) * | 2013-07-16 | 2015-01-22 | University Of Louisville Research Foundation, Inc. | Compositions for mucusal delivery, useful for treating papillomavirus infections |
WO2015152360A1 (ja) | 2014-04-04 | 2015-10-08 | 富士フイルム株式会社 | 不活化全粒子ワクチンを含有するマイクロニードルアレイ製剤およびその投与方法 |
CA2959506C (en) * | 2014-08-29 | 2022-10-18 | Corium International, Inc. | Microstructure array for delivery of active agents |
WO2016036866A1 (en) | 2014-09-04 | 2016-03-10 | Corium International, Inc. | Microstructure array, methods of making, and methods of use |
US10857093B2 (en) | 2015-06-29 | 2020-12-08 | Corium, Inc. | Microarray for delivery of therapeutic agent, methods of use, and methods of making |
HUE046449T2 (hu) | 2016-09-13 | 2020-03-30 | Allergan Inc | Stabilizált, nem fehérje eredetû, clostridiális toxin készítmények |
KR102184153B1 (ko) * | 2019-02-25 | 2020-11-30 | 부산대학교 산학협력단 | 고분자 지지체 기반의 인플루엔자 바이러스 유사 구조체 및 이의 제조방법 |
US11701417B2 (en) | 2019-03-27 | 2023-07-18 | West Virginia University | Vaccine formulation to protect against pertussis |
JP7176100B2 (ja) | 2019-03-28 | 2022-11-21 | 富士フイルム株式会社 | インフルエンザワクチンを含有するマイクロニードルアレイ及びマイクロニードルアレイの製造方法 |
EP4138903A4 (en) * | 2020-04-22 | 2023-12-13 | Emergex USA Corporation | TRANSDERMAL DRUG RELEASE DEVICE WITH CORONAVIRUS VACCINE-COATED MICROPROJECTIONS |
CN113144209A (zh) * | 2021-01-19 | 2021-07-23 | 上海荣盛生物药业有限公司 | 狂犬病疫苗冻干保护剂 |
CN115011566B (zh) * | 2022-05-25 | 2024-01-23 | 辽宁成大生物股份有限公司 | 一种人用狂犬病疫苗中残留dna的去除方法 |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE64891B1 (en) | 1990-03-15 | 1995-09-20 | Becton Dickinson Co | Composition for increased skin concentration of active agents by iontophoresis |
ES2370937T3 (es) * | 1993-09-13 | 2011-12-23 | Protein Sciences Corporation | Un método para producir vacunas antigripales polivalentes a base de hemaglutinina. |
DE4407489A1 (de) | 1994-03-07 | 1995-09-14 | Bayer Ag | Vakzine zur Prävention von Respirations- und Reproduktionserkrankungen des Schweines |
US6290991B1 (en) * | 1994-12-02 | 2001-09-18 | Quandrant Holdings Cambridge Limited | Solid dose delivery vehicle and methods of making same |
DE19612966B4 (de) * | 1996-04-01 | 2009-12-10 | Novartis Vaccines And Diagnostics Gmbh & Co. Kg | MDCK-Zellen und Verfahren zur Vermehrung von Influenzaviren |
US6403098B1 (en) * | 1996-09-26 | 2002-06-11 | Merck & Co., Inc. | Rotavirus vaccine formulations |
US6503231B1 (en) * | 1998-06-10 | 2003-01-07 | Georgia Tech Research Corporation | Microneedle device for transport of molecules across tissue |
AT408615B (de) * | 1998-09-15 | 2002-01-25 | Immuno Ag | Neue influenzavirus-impfstoffzusammensetzung |
JP2001151698A (ja) * | 1999-09-10 | 2001-06-05 | Nichiko Pharmaceutical Co Ltd | インフルエンザワクチン |
US20020095134A1 (en) * | 1999-10-14 | 2002-07-18 | Pettis Ronald J. | Method for altering drug pharmacokinetics based on medical delivery platform |
AU781622B2 (en) | 2000-04-25 | 2005-06-02 | Boehringer Ingelheim Animal Health USA Inc. | Vaccine comprising a tick cement protein |
US6595947B1 (en) * | 2000-05-22 | 2003-07-22 | Becton, Dickinson And Company | Topical delivery of vaccines |
GB0017999D0 (en) * | 2000-07-21 | 2000-09-13 | Smithkline Beecham Biolog | Novel device |
IL154811A0 (en) * | 2000-09-08 | 2003-10-31 | Alza Corp | Methods for inhibiting decrease in transdermal drug flux by inhibition of pathway closure |
HUP0302924A2 (en) | 2000-10-26 | 2003-12-29 | Alza Corp | Transdermal drug delivery devices having coated microprotrusions |
WO2002064193A2 (en) | 2000-12-14 | 2002-08-22 | Georgia Tech Research Corporation | Microneedle devices and production thereof |
JP2004536785A (ja) | 2001-02-23 | 2004-12-09 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 新規なワクチン |
US6508725B1 (en) | 2001-04-18 | 2003-01-21 | Taylor Made Golf Company, Inc. | Golf ball composition and method of manufacture |
BR0209046A (pt) * | 2001-04-20 | 2004-11-09 | Alza Corp | Disposição de microprojeção que possui um agente benéfico contendo revestimento |
US20020193729A1 (en) * | 2001-04-20 | 2002-12-19 | Cormier Michel J.N. | Microprojection array immunization patch and method |
AU2002302814A1 (en) * | 2001-06-08 | 2002-12-23 | Powderject Vaccines, Inc. | Spray freeze-dried compositions |
BR0210628A (pt) * | 2001-06-29 | 2004-08-10 | Becton Dickinson Co | Liberação intradérmica de vacinas e agentes terapêuticos genéticos via microcânula |
US20030186271A1 (en) * | 2001-11-19 | 2003-10-02 | Robin Hwang | Pharmaceutical compositions in particulate form |
ES2271613T3 (es) * | 2002-06-28 | 2007-04-16 | Alza Corporation | Procedimiento de revestimiento de dispositivo de suministro transdermico de farmacos que presenta microportuberancias revestidas. |
-
2005
- 2005-03-18 AU AU2005232541A patent/AU2005232541A1/en not_active Abandoned
- 2005-03-18 MX MXPA06011429A patent/MXPA06011429A/es unknown
- 2005-03-18 WO PCT/US2005/009148 patent/WO2005099751A2/en active Application Filing
- 2005-03-18 JP JP2007506220A patent/JP2007530680A/ja active Pending
- 2005-03-18 BR BRPI0509493-3A patent/BRPI0509493A/pt not_active IP Right Cessation
- 2005-03-18 CA CA002562932A patent/CA2562932A1/en not_active Abandoned
- 2005-03-18 KR KR1020067022824A patent/KR20060135931A/ko not_active Application Discontinuation
- 2005-03-18 US US11/084,631 patent/US20050220854A1/en not_active Abandoned
- 2005-03-18 CN CNA2005800178982A patent/CN101124343A/zh active Pending
- 2005-03-18 EP EP05728255A patent/EP1734993A4/en not_active Withdrawn
- 2005-04-01 AR ARP050101305A patent/AR048862A1/es not_active Application Discontinuation
- 2005-04-01 TW TW094110659A patent/TW200536573A/zh unknown
Also Published As
Publication number | Publication date |
---|---|
EP1734993A4 (en) | 2009-10-21 |
US20050220854A1 (en) | 2005-10-06 |
WO2005099751A2 (en) | 2005-10-27 |
JP2007530680A (ja) | 2007-11-01 |
KR20060135931A (ko) | 2006-12-29 |
MXPA06011429A (es) | 2007-04-25 |
WO2005099751A3 (en) | 2007-09-27 |
TW200536573A (en) | 2005-11-16 |
BRPI0509493A (pt) | 2007-09-11 |
AU2005232541A1 (en) | 2005-10-27 |
CA2562932A1 (en) | 2005-10-27 |
CN101124343A (zh) | 2008-02-13 |
EP1734993A2 (en) | 2006-12-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AR048862A1 (es) | Aparatos y metodos para el suministro transdermico de una vacuna antigripal | |
AR048545A1 (es) | Aparato y metodo para administracion transdermica de vacunas multiples | |
AR046697A1 (es) | Metodo y sistema de administracion transdermica de agente asistido por frecuencia | |
ES2543977T3 (es) | Sistema terapéutico transdérmico para la administración del principio activo buprenorfina | |
AR054300A1 (es) | Aparato y sistema de microproyeccion con escaso potencial infeccioso | |
AR056926A1 (es) | Microproyecciones recubiertas que tienen variabilidad reducida y método para producir las mismas | |
AR046824A1 (es) | Composicion y aparato para la administracion transdermica. | |
BRPI0509788A (pt) | aparato e método para liberação transdérmica de agentes de hormÈnio paratireóides | |
AR048827A1 (es) | Aparato y metodo para la administracion transdermica de agentes basados en fentanil | |
AR046307A1 (es) | Metodo de pretratamiento y sistema para mejorar la administracion transdermica de drogas | |
EP2001453A4 (en) | APPARATUS AND METHOD FOR TRANSDERMAL DELIVERY OF PARATHYROID HORMONE AGENTS FOR TREATING OR PREVENTING OSTEOPENIA | |
CN105982842B (zh) | 微针制剂以及微针制剂的制造方法 | |
AR047229A1 (es) | Administracion de conjugados polimericos de peptidos y proteinas terapeuticos por medio de microproyecciones revestidas | |
AR050292A1 (es) | Aparato y metodo para la entrega transdermica de peptidos natriureticos, para insuficiencia cardiaca | |
AR046696A1 (es) | Aplicador auto-accionante para grupo de microproyecciones | |
WO2011011138A3 (en) | Microneedle delivery device and methods of using same | |
BRPI0415986A (pt) | método e aparelho para reduzir a incidência do uso de tabaco | |
BRPI0514252A (pt) | sistema de elastoplasto de microprotusões sem agulha | |
BR112014009712A2 (pt) | dispositivos implantáveis para a administração de agentes bioativos | |
AR050608A1 (es) | Aparato y metodo para administracion transdermica de factores de crecimiento endotelial vascular | |
TWI659754B (zh) | Micro needle sheet | |
NO20071636L (no) | Flytende allergivaksineformulering for oromukosal administrering | |
JP2015529132A5 (es) | ||
AR054225A1 (es) | Aparato y metodo para suministro transdermico de agentes basados en epoyetina | |
석해용 | Microneedles to Overcome Skin Barriers |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |