AR048545A1 - Aparato y metodo para administracion transdermica de vacunas multiples - Google Patents
Aparato y metodo para administracion transdermica de vacunas multiplesInfo
- Publication number
- AR048545A1 AR048545A1 ARP050101445A ARP050101445A AR048545A1 AR 048545 A1 AR048545 A1 AR 048545A1 AR P050101445 A ARP050101445 A AR P050101445A AR P050101445 A ARP050101445 A AR P050101445A AR 048545 A1 AR048545 A1 AR 048545A1
- Authority
- AR
- Argentina
- Prior art keywords
- array
- regions
- active agent
- immunologically active
- transdermal administration
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title 1
- 238000000576 coating method Methods 0.000 abstract 5
- 239000013543 active substance Substances 0.000 abstract 4
- 239000011248 coating agent Substances 0.000 abstract 4
- 210000002615 epidermis Anatomy 0.000 abstract 2
- 239000002671 adjuvant Substances 0.000 abstract 1
- 230000002500 effect on skin Effects 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0023—Drug applicators using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0046—Solid microneedles
Landscapes
- Health & Medical Sciences (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Medical Informatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Abstract
Un aparato y un método para la administracion transdérmica de un agente inmunologicamente activo que comprende un sistema de aplicacion que posee un arreglo de microproyecciones que incluye una pluralidad de microproyecciones adaptadas para perforar a través del estrato corneo e ingresar a la capa epidérmica, o a las capas epidérmica y dérmica, teniendo el arreglo de microproyecciones una pluralidad de regiones del arreglo teniendo cada una de las regiones del arreglo un recubrimiento biocompatible diferente dispuesto sobre las mismas, donde al menos uno de los recubrimientos de las regiones del arreglo incluye un agente inmunologicamente activo. En una realizacion, cada recubrimiento de las regiones del arreglo incluye un agente inmunologicamente activo diferente. En otra realizacion, el recubrimiento biocompatible en una primera region del arreglo incluye un agente inmunologicamente activo y el recubrimiento biocompatible en una segunda region del arreglo incluye un adyuvante para aumentar la respuesta inmune.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US56195304P | 2004-04-13 | 2004-04-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR048545A1 true AR048545A1 (es) | 2006-05-03 |
Family
ID=35197563
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP050101445A AR048545A1 (es) | 2004-04-13 | 2005-04-13 | Aparato y metodo para administracion transdermica de vacunas multiples |
Country Status (12)
Country | Link |
---|---|
US (1) | US20050271684A1 (es) |
EP (1) | EP1735469A2 (es) |
JP (1) | JP2007537783A (es) |
KR (1) | KR20070011481A (es) |
CN (1) | CN101120101A (es) |
AR (1) | AR048545A1 (es) |
AU (1) | AU2005235990A1 (es) |
BR (1) | BRPI0509897A (es) |
CA (1) | CA2562642A1 (es) |
MX (1) | MXPA06011971A (es) |
TW (1) | TW200600107A (es) |
WO (1) | WO2005103303A2 (es) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020193729A1 (en) * | 2001-04-20 | 2002-12-19 | Cormier Michel J.N. | Microprojection array immunization patch and method |
CA2566759A1 (en) * | 2004-05-19 | 2005-11-24 | Alza Corporation | Method and formulation for transdermal delivery of immunologically active agents |
US20070299388A1 (en) * | 2006-04-25 | 2007-12-27 | Alza Corporation | Microprojection array application with multilayered microprojection member for high drug loading |
EP2146689B1 (en) | 2007-04-16 | 2020-08-12 | Corium, Inc. | Solvent-cast microneedle arrays containing active |
DE102007060599A1 (de) * | 2007-12-15 | 2009-06-18 | Merck Patent Gmbh | Verfahren zur Extraktion von Membranproteinen |
MX2011003277A (es) * | 2008-10-14 | 2012-09-21 | Salubrious Pharmaceuticals LLC | Proceso para el tratamiento de la artritis reumatoide, temblores/enfermedad de parkinson, esclerosis multiple y cancer de tipo no viral. |
CN102196836B (zh) * | 2008-10-25 | 2013-12-18 | 金允圣 | 注射器的针结构 |
US8691502B2 (en) * | 2008-10-31 | 2014-04-08 | Tremrx, Inc. | T-cell vaccination with viral vectors via mechanical epidermal disruption |
CN102281897A (zh) * | 2008-10-31 | 2011-12-14 | T·S·顾巴 | 通过机械破坏表皮进行痘病毒载体的疫苗接种 |
AU2010238605B2 (en) * | 2009-04-24 | 2015-10-29 | Corium Pharma Solutions, Inc. | Methods for manufacturing microprojection arrays |
EP2425242B1 (en) * | 2009-04-29 | 2019-06-05 | Pravin K. Muniyappa | Device and method for the diagnosis of gastrointestinal allergy |
CA2798145C (en) | 2010-05-04 | 2022-10-18 | Corium International, Inc. | Method and device for transdermal delivery of parathyroid hormone using a microprojection array |
JP5225364B2 (ja) | 2010-12-08 | 2013-07-03 | 住友ゴム工業株式会社 | ストリップ、その製造方法および空気入りタイヤの製造方法 |
WO2012151272A2 (en) * | 2011-05-02 | 2012-11-08 | Tremrx, Inc. | T-cell vaccination with viral vectors via mechanical epidermal disruption |
AU2013364053B2 (en) | 2012-12-21 | 2018-08-30 | Corium Pharma Solutions, Inc. | Microarray for delivery of therapeutic agent and methods of use |
CN105142711B (zh) | 2013-03-12 | 2019-01-22 | 考里安国际公司 | 微突起施加器 |
US10668260B2 (en) | 2013-03-12 | 2020-06-02 | Takeda Pharmaceutical Company Limited | Microneedle patch |
US10384045B2 (en) | 2013-03-15 | 2019-08-20 | Corium, Inc. | Microarray with polymer-free microstructures, methods of making, and methods of use |
CA2906541C (en) | 2013-03-15 | 2022-06-21 | Corium International, Inc. | Microarray for delivery of therapeutic agent and methods of use |
CN106061546A (zh) * | 2014-02-10 | 2016-10-26 | Lts勒曼治疗系统股份公司 | 微针系统及其制造方法 |
US10624843B2 (en) | 2014-09-04 | 2020-04-21 | Corium, Inc. | Microstructure array, methods of making, and methods of use |
WO2016114213A1 (ja) * | 2015-01-13 | 2016-07-21 | 凸版印刷株式会社 | 経皮投与デバイス |
US10857093B2 (en) | 2015-06-29 | 2020-12-08 | Corium, Inc. | Microarray for delivery of therapeutic agent, methods of use, and methods of making |
MX2019002835A (es) | 2016-09-13 | 2019-09-04 | Allergan Inc | Composiciones no proteínicas de toxina clostridial. |
US11241563B2 (en) | 2016-12-22 | 2022-02-08 | Johnson & Johnson Consumer Inc. | Microneedle arrays and methods for making and using |
US20200215187A1 (en) * | 2017-07-24 | 2020-07-09 | Bioserentach Co., Ltd. | Vaccine adjuvant and microneedle preparation |
WO2019190267A1 (ko) * | 2018-03-30 | 2019-10-03 | 랩앤피플주식회사 | 멀티형 마이크로 니들 |
AU2019293644B2 (en) | 2018-06-29 | 2024-08-22 | Johnson & Johnson Consumer Inc. | Three-dimensional microfluidics devices for the delivery of actives |
US11697009B2 (en) * | 2019-09-06 | 2023-07-11 | Industry-Academic Cooperation Foundation, Yonsei University | Microneedle patch, micro needle system and method of fabricating the same |
US11796548B2 (en) | 2020-04-22 | 2023-10-24 | The United States Of America, As Represented By The Secretary Of Agriculture | Continuous stable cell line for identification of infectious African swine fever virus in clinical samples |
CN115068602B (zh) * | 2022-08-22 | 2022-11-01 | 北京华诺泰生物医药科技有限公司 | 一种表面改性氧化铝的复合疫苗佐剂、制备方法及应用 |
Family Cites Families (51)
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USRE25637E (en) * | 1964-09-08 | Means for vaccinating | ||
US3136314A (en) * | 1960-08-01 | 1964-06-09 | Kravitz Harvey | Vaccinating devices |
US3964482A (en) * | 1971-05-17 | 1976-06-22 | Alza Corporation | Drug delivery device |
BE795384A (fr) * | 1972-02-14 | 1973-08-13 | Ici Ltd | Pansements |
OA05448A (fr) * | 1975-10-16 | 1981-03-31 | Manufrance Manufacture Francai | Dispositif vaccinateur multipénétrant. |
DE3113984C2 (de) * | 1981-04-07 | 1983-12-01 | Bodenseewerk Perkin-Elmer & Co GmbH, 7770 Überlingen | Doppelmonochromator |
US4877612A (en) * | 1985-05-20 | 1989-10-31 | Frank M. Berger | Immunological adjuvant and process for preparing the same, pharmaceutical compositions, and process |
EP0429842B1 (en) * | 1989-10-27 | 1996-08-28 | Korea Research Institute Of Chemical Technology | Device for the transdermal administration of protein or peptide drug |
US5279544A (en) * | 1990-12-13 | 1994-01-18 | Sil Medics Ltd. | Transdermal or interdermal drug delivery devices |
US5487726A (en) * | 1994-06-16 | 1996-01-30 | Ryder International Corporation | Vaccine applicator system |
US6290991B1 (en) * | 1994-12-02 | 2001-09-18 | Quandrant Holdings Cambridge Limited | Solid dose delivery vehicle and methods of making same |
US5659578A (en) * | 1994-11-23 | 1997-08-19 | At&T Wireless Services, Inc. | High rate Reed-Solomon concatenated trellis coded 16 star QAM system for transmission of data over cellular mobile radio |
AU5740496A (en) * | 1995-05-22 | 1996-12-11 | General Hospital Corporation, The | Micromechanical device and method for enhancing delivery of compounds through the skin |
DK0914178T3 (da) * | 1996-06-18 | 2003-04-22 | Alza Corp | Anordning til forøgelse af transdermal afgivelse eller prøveudtagning af et middel |
US5916524A (en) * | 1997-07-23 | 1999-06-29 | Bio-Dot, Inc. | Dispensing apparatus having improved dynamic range |
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JP2001525227A (ja) * | 1997-12-11 | 2001-12-11 | アルザ・コーポレーション | 経皮的薬剤流量を高めるための装置 |
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US6855372B2 (en) * | 2001-03-16 | 2005-02-15 | Alza Corporation | Method and apparatus for coating skin piercing microprojections |
CN101129327A (zh) * | 2001-04-20 | 2008-02-27 | 阿尔扎公司 | 具有包含有益药剂的涂层的微小突出物阵列 |
US20020193729A1 (en) * | 2001-04-20 | 2002-12-19 | Cormier Michel J.N. | Microprojection array immunization patch and method |
WO2003002069A2 (en) * | 2001-06-29 | 2003-01-09 | Becton, Dickinson And Company | Intradermal delivery of vaccines and gene therapeutic agents via microcannula |
US20030199810A1 (en) * | 2001-11-30 | 2003-10-23 | Trautman Joseph Creagan | Methods and apparatuses for forming microprojection arrays |
DK1465535T3 (da) * | 2001-12-20 | 2008-04-07 | Alza Corp | Mikrofremspring til gennemstikning af huden med stikdybdestyring |
WO2003101507A2 (en) * | 2002-03-11 | 2003-12-11 | Altea Therapeutics Corporation | Transdermal drug delivery device, method and use |
AR040302A1 (es) * | 2002-06-28 | 2005-03-23 | Alza Corp | Dispositivos para la liberacion transdermica de farmacos, que presentan microprotrusiones recubiertas |
TW200409657A (en) * | 2002-08-08 | 2004-06-16 | Alza Corp | Transdermal vaccine delivery device having coated microprotrusions |
AR042815A1 (es) * | 2002-12-26 | 2005-07-06 | Alza Corp | Dispositivo de suministro de agente activo que tiene miembros compuestos |
WO2005004729A1 (en) * | 2003-06-30 | 2005-01-20 | Alza Corporation | Method for coating skin piercing microprojections |
ES2437565T3 (es) * | 2003-06-30 | 2014-01-13 | Alza Corporation | Formulaciones para microproyecciones revestidas que contienen contraiones no volátiles |
US20050123507A1 (en) * | 2003-06-30 | 2005-06-09 | Mahmoud Ameri | Formulations for coated microprojections having controlled solubility |
TW200513280A (en) * | 2003-07-02 | 2005-04-16 | Alza Corp | Microprojection array immunization patch and method |
CA2543280A1 (en) * | 2003-10-28 | 2005-05-19 | Alza Corporation | Delivery of polymer conjugates of therapeutic peptides and proteins via coated microporjections |
KR20060099523A (ko) * | 2003-10-31 | 2006-09-19 | 알자 코포레이션 | 미세 돌출부 어레이를 위한 자가 작동 어플리케이터 |
AU2004292954A1 (en) * | 2003-11-13 | 2005-06-09 | Alza Corporation | Composition and apparatus for transdermal delivery |
JP2007530680A (ja) * | 2004-04-01 | 2007-11-01 | アルザ・コーポレーシヨン | インフルエンザワクチンの経皮デリバリーのための装置および方法 |
ES2568259T3 (es) * | 2004-05-13 | 2016-04-28 | Alza Corporation | Aparato y método para la administración transdérmica de agentes de hormona paratiroidea |
-
2005
- 2005-03-18 WO PCT/US2005/009152 patent/WO2005103303A2/en active Application Filing
- 2005-03-18 BR BRPI0509897-1A patent/BRPI0509897A/pt not_active Application Discontinuation
- 2005-03-18 AU AU2005235990A patent/AU2005235990A1/en not_active Abandoned
- 2005-03-18 CA CA002562642A patent/CA2562642A1/en not_active Abandoned
- 2005-03-18 US US11/084,635 patent/US20050271684A1/en not_active Abandoned
- 2005-03-18 KR KR1020067023637A patent/KR20070011481A/ko not_active Application Discontinuation
- 2005-03-18 MX MXPA06011971A patent/MXPA06011971A/es unknown
- 2005-03-18 EP EP05725915A patent/EP1735469A2/en not_active Withdrawn
- 2005-03-18 CN CNA2005800191879A patent/CN101120101A/zh active Pending
- 2005-03-18 JP JP2007508359A patent/JP2007537783A/ja active Pending
- 2005-04-12 TW TW094111542A patent/TW200600107A/zh unknown
- 2005-04-13 AR ARP050101445A patent/AR048545A1/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
TW200600107A (en) | 2006-01-01 |
AU2005235990A1 (en) | 2005-11-03 |
MXPA06011971A (es) | 2007-04-16 |
EP1735469A2 (en) | 2006-12-27 |
CN101120101A (zh) | 2008-02-06 |
JP2007537783A (ja) | 2007-12-27 |
CA2562642A1 (en) | 2005-11-03 |
KR20070011481A (ko) | 2007-01-24 |
WO2005103303A3 (en) | 2007-10-18 |
BRPI0509897A (pt) | 2007-08-07 |
WO2005103303A2 (en) | 2005-11-03 |
US20050271684A1 (en) | 2005-12-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |