AR048827A1 - Aparato y metodo para la administracion transdermica de agentes basados en fentanil - Google Patents

Aparato y metodo para la administracion transdermica de agentes basados en fentanil

Info

Publication number
AR048827A1
AR048827A1 ARP050101446A ARP050101446A AR048827A1 AR 048827 A1 AR048827 A1 AR 048827A1 AR P050101446 A ARP050101446 A AR P050101446A AR P050101446 A ARP050101446 A AR P050101446A AR 048827 A1 AR048827 A1 AR 048827A1
Authority
AR
Argentina
Prior art keywords
fentanyl
microprojections
transdermal administration
fentanil
based agents
Prior art date
Application number
ARP050101446A
Other languages
English (en)
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of AR048827A1 publication Critical patent/AR048827A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Un aparato y un método para la administracion por vía transdérmica de un agente biologicamente activo, basados en fentanil, que comprende un sistema de administracion que posee un miembro ( o sistema) con microproyecciones que incluye una pluralidad de microproyecciones (o un arreglo de las mismas) adaptadas paraperforar el estrato corneo e ingresar a la capa epidérmica o a las capas epidérmica y dérmica. En una realizacion, el agente basado en fentanil está contenido en un recubrimiento biocompatible que se aplica al miembro con microproyecciones En una realizacion adicional, el sistema de administracion incluye un pack de gel que posee una formulacion de hidrogel que contiene un agente basado en fentanil que se dispone sobre el miembro microproyecciones después de la aplicacion a la piel de un paciente. En una realizacion adicional, el agente basado en fentanil está contenido tanto en el recubrimiento como en la formulacion de hidrogel.
ARP050101446A 2004-04-13 2005-04-13 Aparato y metodo para la administracion transdermica de agentes basados en fentanil AR048827A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US56194904P 2004-04-13 2004-04-13

Publications (1)

Publication Number Publication Date
AR048827A1 true AR048827A1 (es) 2006-05-31

Family

ID=35197490

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP050101446A AR048827A1 (es) 2004-04-13 2005-04-13 Aparato y metodo para la administracion transdermica de agentes basados en fentanil

Country Status (12)

Country Link
US (1) US20050226922A1 (es)
EP (1) EP1737434A2 (es)
JP (1) JP2007532645A (es)
KR (1) KR20070011469A (es)
CN (1) CN101027045A (es)
AR (1) AR048827A1 (es)
AU (1) AU2005235075A1 (es)
BR (1) BRPI0509901A (es)
CA (1) CA2562731A1 (es)
MX (1) MXPA06011972A (es)
TW (1) TW200602099A (es)
WO (1) WO2005102334A2 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2656860T3 (da) 2005-06-17 2021-07-26 Wisconsin Alumni Res Found Topikale vasokonstriktorpræparater og fremgangsmåder til beskyttelse af celler under cancer kemoterapi og strålingsterapi
AU2012202731B2 (en) * 2005-06-17 2014-06-19 Wisconsin Alumni Research Foundation Topical vasoconstrictor preparations and methods for protecting cells during cancer chemotherapy and radiotherapy
AU2014202738B2 (en) * 2005-06-17 2016-05-12 Wisconsin Alumni Research Foundation Topical vasoconstrictor preparations and methods for protecting cells during cancer chemotherapy and radiotherapy
BRPI0620671A2 (pt) * 2005-12-14 2011-11-22 Ariana Holdings Pty Ltd dispositivo para aplicar um composto quìmico e método de aplicação de um composto quìmico
WO2007127815A2 (en) * 2006-04-25 2007-11-08 Alza Corporation Microprojection array application with multilayered microprojection member for high drug loading
WO2007127811A2 (en) * 2006-04-25 2007-11-08 Alza Corporation Microprojection array application with grouped microprojections for high drug loading
US8173666B2 (en) 2007-03-12 2012-05-08 Nektar Therapeutics Oligomer-opioid agonist conjugates
US10512644B2 (en) 2007-03-12 2019-12-24 Inheris Pharmaceuticals, Inc. Oligomer-opioid agonist conjugates
HUP0700828A2 (en) * 2007-12-20 2010-01-28 Richter Gedeon Nyrt Transdermal pharmaceutical compositions containing tolperisone alone and in combination
US20110237614A1 (en) * 2008-09-16 2011-09-29 Nektar Therapeutics Pegylated Opioids with Low Potential for Abuse
US8894630B2 (en) 2009-11-13 2014-11-25 The Invention Science Fund I, Llc Device, system, and method for targeted delivery of anti-inflammatory medicaments to a mammalian subject
US8888761B2 (en) 2009-11-13 2014-11-18 The Invention Science Fund I, Llc Device, system, and method for targeted delivery of anti-inflammatory medicaments to a mammalian subject
US8439896B2 (en) * 2009-11-13 2013-05-14 The Invention Science Fund I, Llc Device, system, and method for targeted delivery of anti-inflammatory medicaments to a mammalian subject
WO2011096468A1 (ja) 2010-02-05 2011-08-11 株式会社ニチレイバイオサイエンス 免疫組織化学染色用前処理液及びその濃縮液
CN105815785A (zh) * 2016-03-31 2016-08-03 常州大学 一种从黄瓜中提取丙醇二酸制备除脂粉的方法
US9650338B1 (en) 2016-07-29 2017-05-16 VDM Biochemicals, Inc. Opioid antagonist compounds and methods of making and using
CN110536861B (zh) 2017-04-18 2023-07-04 突破技术有限责任公司 硫的生产
EP3723725B1 (de) * 2017-12-14 2022-02-02 LTS LOHMANN Therapie-Systeme AG Mikronadelarray aufweisend einen wirkstoff in form von salzen
CN108318646A (zh) * 2018-03-27 2018-07-24 苏州桓晨医疗科技有限公司 一种模拟药物体外释放的释放介质
EP4138903A4 (en) * 2020-04-22 2023-12-13 Emergex USA Corporation TRANSDERMAL DRUG RELEASE DEVICE WITH CORONAVIRUS VACCINE-COATED MICROPROJECTIONS

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3964482A (en) * 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
BE795384A (fr) * 1972-02-14 1973-08-13 Ici Ltd Pansements
US4486423A (en) * 1983-04-21 1984-12-04 Janssen Pharmaceutica Inc. Stable fentanyl composition
US5080646A (en) * 1988-10-03 1992-01-14 Alza Corporation Membrane for electrotransport transdermal drug delivery
US5169382A (en) * 1988-10-03 1992-12-08 Alza Corporation Membrane for electrotransport transdermal drug delivery
US5147296A (en) * 1988-10-03 1992-09-15 Alza Corporation Membrane for electrotransport transdermal drug delivery
US5378475A (en) * 1991-02-21 1995-01-03 University Of Kentucky Research Foundation Sustained release drug delivery devices
US5916596A (en) * 1993-02-22 1999-06-29 Vivorx Pharmaceuticals, Inc. Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof
WO1996037155A1 (en) * 1995-05-22 1996-11-28 Silicon Microdevices, Inc. Micromechanical device and method for enhancing delivery of compounds through the skin
US6143037A (en) * 1996-06-12 2000-11-07 The Regents Of The University Of Michigan Compositions and methods for coating medical devices
US5916524A (en) * 1997-07-23 1999-06-29 Bio-Dot, Inc. Dispensing apparatus having improved dynamic range
US5741554A (en) * 1996-07-26 1998-04-21 Bio Dot, Inc. Method of dispensing a liquid reagent
US5738728A (en) * 1996-07-26 1998-04-14 Bio Dot, Inc. Precision metered aerosol dispensing apparatus
US5743960A (en) * 1996-07-26 1998-04-28 Bio-Dot, Inc. Precision metered solenoid valve dispenser
KR100561892B1 (ko) * 1997-12-11 2006-03-16 알자 코포레이션 경피성 작용제 유동률을 증진시키기 위한 장치
US6050988A (en) * 1997-12-11 2000-04-18 Alza Corporation Device for enhancing transdermal agent flux
US6091975A (en) * 1998-04-01 2000-07-18 Alza Corporation Minimally invasive detecting device
JP4205778B2 (ja) * 1998-04-17 2009-01-07 久光製薬株式会社 貼付製剤
EP1169025B1 (en) * 1999-04-01 2005-08-24 Alza Corporation Transdermal drug delivery devices comprising a polyurethane drug reservoir
US6250023B1 (en) * 1999-10-19 2001-06-26 Bruce A. Donoho Preventive device against nuisance from birds
WO2001064149A1 (en) * 2000-02-29 2001-09-07 Jie Zhang Improved transdermal drug patch
JP5507030B2 (ja) * 2000-09-08 2014-05-28 アルザ・コーポレーシヨン 経路閉鎖を阻害することによる経皮的薬物流動の減少の抑制方法
US20020119187A1 (en) * 2000-09-29 2002-08-29 Cantor Adam S. Composition for the transdermal delivery of fentanyl
MXPA03003303A (es) * 2000-10-13 2004-12-13 Johnson & Johnson Retenedor del miembro de microprotrusion para aplicador de impacto.
US6855372B2 (en) * 2001-03-16 2005-02-15 Alza Corporation Method and apparatus for coating skin piercing microprojections
EP1392389B1 (en) * 2001-04-20 2009-10-07 Alza Corporation Microprojection array having a beneficial agent containing coating
DE10141650C1 (de) * 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
US7790215B2 (en) * 2002-03-26 2010-09-07 Purdue Pharma Lp Sustained-release gel coated compositions

Also Published As

Publication number Publication date
JP2007532645A (ja) 2007-11-15
BRPI0509901A (pt) 2007-08-07
EP1737434A2 (en) 2007-01-03
TW200602099A (en) 2006-01-16
MXPA06011972A (es) 2007-04-16
WO2005102334A2 (en) 2005-11-03
CA2562731A1 (en) 2005-11-03
AU2005235075A1 (en) 2005-11-03
CN101027045A (zh) 2007-08-29
US20050226922A1 (en) 2005-10-13
KR20070011469A (ko) 2007-01-24
WO2005102334A3 (en) 2006-02-09

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