AR054225A1 - Aparato y metodo para suministro transdermico de agentes basados en epoyetina - Google Patents

Aparato y metodo para suministro transdermico de agentes basados en epoyetina

Info

Publication number
AR054225A1
AR054225A1 AR20060100552A ARP060100552A AR054225A1 AR 054225 A1 AR054225 A1 AR 054225A1 AR 20060100552 A AR20060100552 A AR 20060100552A AR P060100552 A ARP060100552 A AR P060100552A AR 054225 A1 AR054225 A1 AR 054225A1
Authority
AR
Argentina
Prior art keywords
epoietin
agent
microprojection member
epoyetine
layer
Prior art date
Application number
AR20060100552A
Other languages
English (en)
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of AR054225A1 publication Critical patent/AR054225A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1816—Erythropoietin [EPO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Medical Informatics (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)

Abstract

Un aparato y un método para suministrar transdémicamente un agente biologicamente activo que comprende un sistema de suministro que posee un miembro (o sistema) de microproyeccion que incluye una pluralidad de microproyecciones (o una disposicion de las mismas) que están adaptadas para penetrar la capa cornea hacia el interior de la capa de epidermis subyacente, o de la capa de epidermis y de dermis. En una realizacion, un agente basado en Epoyetina está contenido en un recubrimiento biocompatible que es aplicado al miembro de microproyeccion. En una realizacion adicional, el sistema de suministro incluye un ôgel packö que posee una formulacion de hidrogel que contiene un agente basado en Epoyetina que es dispuesta sobre el miembro de microproyeccion luego de la aplicacion la piel de un paciente. En una realizacion alternativa, el agente basado en Epoyetina está contenido tanto en el recubrimiento como en la formulacion de hidrogel.
AR20060100552A 2005-02-16 2006-02-15 Aparato y metodo para suministro transdermico de agentes basados en epoyetina AR054225A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US65367605P 2005-02-16 2005-02-16

Publications (1)

Publication Number Publication Date
AR054225A1 true AR054225A1 (es) 2007-06-13

Family

ID=36917058

Family Applications (1)

Application Number Title Priority Date Filing Date
AR20060100552A AR054225A1 (es) 2005-02-16 2006-02-15 Aparato y metodo para suministro transdermico de agentes basados en epoyetina

Country Status (9)

Country Link
US (1) US20060182789A1 (es)
EP (1) EP1853231A2 (es)
JP (1) JP2008530230A (es)
CN (1) CN101160117A (es)
AR (1) AR054225A1 (es)
AU (1) AU2006214236A1 (es)
CA (1) CA2597931A1 (es)
TW (1) TW200738252A (es)
WO (1) WO2006089056A2 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2625145T3 (es) * 2007-12-28 2017-07-18 Augustinus Bader Aplicación tópica y formulación de eritropoyetina para cicatrizar heridas cutáneas
DE102008063040A1 (de) 2008-12-23 2010-06-24 Mt Derm Gmbh Vorrichtung zum Einbringen einer Flüssigkeit in eine menschliche oder eine tierische Haut sowie Verfahren zum Betreiben der Vorrichtung
JP6121674B2 (ja) * 2011-09-12 2017-04-26 コスメディ製薬株式会社 マイクロニードル迅速溶解法
KR20180049036A (ko) * 2015-09-04 2018-05-10 레미도르 바이오메드 엘티디. 국소 에리트로포이에틴 제형 및 상기 제형으로 상처 치유를 개선시키는 방법 및 제형의 미용학적 용도
JP6997866B2 (ja) 2018-05-23 2022-01-18 富士フイルム株式会社 日本脳炎ワクチン含有マイクロニードルアレイ

Family Cites Families (32)

* Cited by examiner, † Cited by third party
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USRE25637E (en) * 1964-09-08 Means for vaccinating
US3964482A (en) * 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
BE795384A (fr) * 1972-02-14 1973-08-13 Ici Ltd Pansements
US5080646A (en) * 1988-10-03 1992-01-14 Alza Corporation Membrane for electrotransport transdermal drug delivery
US5169382A (en) * 1988-10-03 1992-12-08 Alza Corporation Membrane for electrotransport transdermal drug delivery
US5147296A (en) * 1988-10-03 1992-09-15 Alza Corporation Membrane for electrotransport transdermal drug delivery
EP0429842B1 (en) * 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Device for the transdermal administration of protein or peptide drug
KR0166088B1 (ko) * 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
US20030035845A1 (en) * 1992-06-11 2003-02-20 Zale Stephen E. Composition for sustained release of non-aggregated erythropoietin
WO1996037155A1 (en) * 1995-05-22 1996-11-28 Silicon Microdevices, Inc. Micromechanical device and method for enhancing delivery of compounds through the skin
US5738728A (en) * 1996-07-26 1998-04-14 Bio Dot, Inc. Precision metered aerosol dispensing apparatus
US5741554A (en) * 1996-07-26 1998-04-21 Bio Dot, Inc. Method of dispensing a liquid reagent
US5916524A (en) * 1997-07-23 1999-06-29 Bio-Dot, Inc. Dispensing apparatus having improved dynamic range
US5743960A (en) * 1996-07-26 1998-04-28 Bio-Dot, Inc. Precision metered solenoid valve dispenser
KR100453132B1 (ko) * 1996-12-20 2004-10-15 앨자 코포레이션 경피 약제 플럭스를 향상시키기 위한 장치 및 방법
DE69806963T2 (de) * 1997-12-11 2002-11-21 Alza Corp., Mountain View Vorrichtung zur erhöhung des transdermalen wirkstoffeflusses
ATE302041T1 (de) * 1997-12-11 2005-09-15 Alza Corp Vorrichtung zur erhöhung des transdermalen wirkstoffeflusses
US6091975A (en) * 1998-04-01 2000-07-18 Alza Corporation Minimally invasive detecting device
CN100421653C (zh) * 2000-09-08 2008-10-01 阿尔扎公司 通过抑制通道关闭来抑制药物透皮通量减少的方法
RU2278623C2 (ru) * 2000-10-13 2006-06-27 Алза Корпорейшн Держатель микровыступающего элемента для силового аппликатора
JP4659332B2 (ja) * 2000-10-13 2011-03-30 アルザ・コーポレーシヨン 微小突起を用いて皮膚を穿孔するための装置および方法
JP4659336B2 (ja) * 2000-10-26 2011-03-30 アルザ・コーポレーシヨン 被覆された微細突出物を有する経皮的薬剤配達装置
US6855372B2 (en) * 2001-03-16 2005-02-15 Alza Corporation Method and apparatus for coating skin piercing microprojections
BR0209046A (pt) * 2001-04-20 2004-11-09 Alza Corp Disposição de microprojeção que possui um agente benéfico contendo revestimento
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AU2003275301A1 (en) * 2002-09-30 2004-04-23 Alza Corporation Drug delivery device having coated microprojections incorporating vasoconstrictors
CA2530531A1 (en) * 2003-06-30 2005-01-20 Alza Corporation Formulations for coated microprojections containing non-volatile counterions
EP1638468B1 (en) * 2003-06-30 2007-08-15 Alza Corporation Method for coating skin piercing microprojections
TW200513280A (en) * 2003-07-02 2005-04-16 Alza Corp Microprojection array immunization patch and method
CA2543084A1 (en) * 2003-10-24 2005-05-12 Alza Corporation Apparatus and method for enhancing transdermal drug delivery
JP5277456B2 (ja) * 2005-01-31 2013-08-28 アルザ コーポレイション 低い変動性を有するコーティングマイクロプロジェクション、及びその生成法
JP2008529750A (ja) * 2005-02-16 2008-08-07 アルザ コーポレイション 生体適合性が改善されたマイクロプロジェクションアレイ

Also Published As

Publication number Publication date
WO2006089056A2 (en) 2006-08-24
CA2597931A1 (en) 2006-08-24
AU2006214236A1 (en) 2006-08-24
TW200738252A (en) 2007-10-16
US20060182789A1 (en) 2006-08-17
JP2008530230A (ja) 2008-08-07
EP1853231A2 (en) 2007-11-14
WO2006089056A3 (en) 2006-12-07
CN101160117A (zh) 2008-04-09

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