TW200738252A - Apparatus and method for transdermal delivery of Epoetin-based agents - Google Patents

Apparatus and method for transdermal delivery of Epoetin-based agents

Info

Publication number
TW200738252A
TW200738252A TW095104978A TW95104978A TW200738252A TW 200738252 A TW200738252 A TW 200738252A TW 095104978 A TW095104978 A TW 095104978A TW 95104978 A TW95104978 A TW 95104978A TW 200738252 A TW200738252 A TW 200738252A
Authority
TW
Taiwan
Prior art keywords
epoetin
microprojection member
based agent
transdermal delivery
based agents
Prior art date
Application number
TW095104978A
Other languages
English (en)
Inventor
Mahmoud Ameri
Michel J N Cormier
Yuh-Fun Maa
Peter Daddona
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of TW200738252A publication Critical patent/TW200738252A/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1816Erythropoietin [EPO]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046Solid microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Medical Informatics (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TW095104978A 2005-02-16 2006-02-15 Apparatus and method for transdermal delivery of Epoetin-based agents TW200738252A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US65367605P 2005-02-16 2005-02-16

Publications (1)

Publication Number Publication Date
TW200738252A true TW200738252A (en) 2007-10-16

Family

ID=36917058

Family Applications (1)

Application Number Title Priority Date Filing Date
TW095104978A TW200738252A (en) 2005-02-16 2006-02-15 Apparatus and method for transdermal delivery of Epoetin-based agents

Country Status (9)

Country Link
US (1) US20060182789A1 (zh)
EP (1) EP1853231A2 (zh)
JP (1) JP2008530230A (zh)
CN (1) CN101160117A (zh)
AR (1) AR054225A1 (zh)
AU (1) AU2006214236A1 (zh)
CA (1) CA2597931A1 (zh)
TW (1) TW200738252A (zh)
WO (1) WO2006089056A2 (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2222327T3 (en) * 2007-12-28 2017-05-15 Augustinus Bader TOPICAL USE AND FORMULATION OF ERYTHROPOIETIN FOR HEALTH CARE
DE102008063040A1 (de) 2008-12-23 2010-06-24 Mt Derm Gmbh Vorrichtung zum Einbringen einer Flüssigkeit in eine menschliche oder eine tierische Haut sowie Verfahren zum Betreiben der Vorrichtung
JP6121674B2 (ja) * 2011-09-12 2017-04-26 コスメディ製薬株式会社 マイクロニードル迅速溶解法
WO2017037655A1 (en) * 2015-09-04 2017-03-09 Remedor Biomed Ltd. Topical erythropoietin formulations and methods for improving wound healing with and cosmetic use of the formulations
EP3797820A4 (en) 2018-05-23 2021-09-15 FUJIFILM Corporation JAPAN ENZEPHALITIS VACCINE CONTAINING MICRON-NEEDLE ARRANGEMENT

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USRE25637E (en) * 1964-09-08 Means for vaccinating
US3964482A (en) * 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
BE795384A (fr) * 1972-02-14 1973-08-13 Ici Ltd Pansements
US5080646A (en) * 1988-10-03 1992-01-14 Alza Corporation Membrane for electrotransport transdermal drug delivery
US5169382A (en) * 1988-10-03 1992-12-08 Alza Corporation Membrane for electrotransport transdermal drug delivery
US5147296A (en) * 1988-10-03 1992-09-15 Alza Corporation Membrane for electrotransport transdermal drug delivery
EP0429842B1 (en) * 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Device for the transdermal administration of protein or peptide drug
KR0166088B1 (ko) * 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
US20030035845A1 (en) * 1992-06-11 2003-02-20 Zale Stephen E. Composition for sustained release of non-aggregated erythropoietin
WO1996037155A1 (en) * 1995-05-22 1996-11-28 Silicon Microdevices, Inc. Micromechanical device and method for enhancing delivery of compounds through the skin
US5738728A (en) * 1996-07-26 1998-04-14 Bio Dot, Inc. Precision metered aerosol dispensing apparatus
US5916524A (en) * 1997-07-23 1999-06-29 Bio-Dot, Inc. Dispensing apparatus having improved dynamic range
US5743960A (en) * 1996-07-26 1998-04-28 Bio-Dot, Inc. Precision metered solenoid valve dispenser
US5741554A (en) * 1996-07-26 1998-04-21 Bio Dot, Inc. Method of dispensing a liquid reagent
DK0957972T3 (da) * 1996-12-20 2003-07-21 Alza Corp Anordning og fremgangsmåde til at forøge transdermal middelflux
JP4061022B2 (ja) * 1997-12-11 2008-03-12 アルザ・コーポレーション 経皮輸送剤の流量促進装置
DK1037686T3 (da) * 1997-12-11 2006-01-02 Alza Corp Apparat til forögelse af transdermal gennemströmning af midler
US6091975A (en) * 1998-04-01 2000-07-18 Alza Corporation Minimally invasive detecting device
CA2422200A1 (en) * 2000-09-08 2002-03-14 Alza Corporation Methods for inhibiting decrease in transdermal drug flux by inhibition of pathway closure
DE60136951D1 (de) * 2000-10-13 2009-01-22 Alza Corp Mikronadelelementhalter für schlagapplikator
KR20030068136A (ko) * 2000-10-13 2003-08-19 알자 코포레이션 미세 돌기부로 피부를 천공하기 위한 장치 및 방법
EP2085109A3 (en) * 2000-10-26 2009-09-02 Alza Corporation Transdermal drug delivery devices having coated microprotrusions
US6855372B2 (en) * 2001-03-16 2005-02-15 Alza Corporation Method and apparatus for coating skin piercing microprojections
CA2444883A1 (en) * 2001-04-20 2002-10-31 Alza Corporation Microprojection array having a beneficial agent containing coating
AU2003275311A1 (en) * 2002-09-16 2004-04-30 Sung-Yun Kwon Solid micro-perforators and methods of use
CA2516547A1 (en) * 2002-09-30 2004-04-15 Alza Corporation Drug delivery device having coated microprojections incorporating vasoconstrictors
JP5456234B2 (ja) * 2003-06-30 2014-03-26 アルザ・コーポレーシヨン 非揮発性の対イオンを含有する被覆された微小突起のための製剤
DE602004008278T2 (de) * 2003-06-30 2008-02-14 Alza Corp., Mountain View Transdermale Abgabevorrichtung zur Abgabe eines biologisch aktiven Mittels mit hydrophober und hydrophiler Beschichtung
KR20060037320A (ko) * 2003-07-02 2006-05-03 알자 코포레이션 미세돌출부 어레이 면역화 패치 및 방법
WO2005041871A2 (en) * 2003-10-24 2005-05-12 Alza Corporation Apparatus and method for enhancing transdermal drug delivery
EP1843811A2 (en) * 2005-01-31 2007-10-17 Alza Corporation, Inc. Coated microprojections having reduced variability and method for producing same
CN101119764A (zh) * 2005-02-16 2008-02-06 阿尔扎公司 具有改善的生物相容性的微突出物阵列

Also Published As

Publication number Publication date
JP2008530230A (ja) 2008-08-07
AR054225A1 (es) 2007-06-13
WO2006089056A3 (en) 2006-12-07
CA2597931A1 (en) 2006-08-24
CN101160117A (zh) 2008-04-09
AU2006214236A1 (en) 2006-08-24
WO2006089056A2 (en) 2006-08-24
EP1853231A2 (en) 2007-11-14
US20060182789A1 (en) 2006-08-17

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