PA8589101A1 - Lamina revestida de adhesivo para administracion dermica de un inhibidor selectivo de ciclooxigenasa-2 - Google Patents

Lamina revestida de adhesivo para administracion dermica de un inhibidor selectivo de ciclooxigenasa-2

Info

Publication number
PA8589101A1
PA8589101A1 PA20038589101A PA8589101A PA8589101A1 PA 8589101 A1 PA8589101 A1 PA 8589101A1 PA 20038589101 A PA20038589101 A PA 20038589101A PA 8589101 A PA8589101 A PA 8589101A PA 8589101 A1 PA8589101 A1 PA 8589101A1
Authority
PA
Panama
Prior art keywords
subject
composition
active agent
understands
skin area
Prior art date
Application number
PA20038589101A
Other languages
English (en)
Inventor
Gary D Ewing
Guang Wei Lu
Brenda M Stoller
Kathryn M Kienle
Original Assignee
Pharmacia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp filed Critical Pharmacia Corp
Publication of PA8589101A1 publication Critical patent/PA8589101A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Materials For Medical Uses (AREA)

Abstract

UNA COMPOSICION FARMACEUTICA PARA LA APLICACION SOBRE UN AREA DE PIEL DE UN SUJETO PARA TRATAMIENTO LOCAL Y/O SITEMICO DE UN TRASTORNO MEDIADO POR COX-2 COMPRENDE UNA LAMINA DE SOPORTE QUE SE PUEDE ADAPTAR FLEXIBLEMENTE AL AREA DE PIEL, TENIENDO LA LAMINA DE SOPORTE SUPERFICIES OPUESTAS QUE SON RESPECTIVAMENTE DISTALES Y PROXIMALES A LA PIEL CUANDO SE APLICA; Y UN REVESTIMIENTO SOBRE LA SUPERFICIE PROXIMAL DE LA LAMINA DE SOPORTE QUE COMPRENDE (a) UN ADHESIVO Y (b) UN AGENTE ACTIVO QUE COMPRENDE VALDECOXIB O UNO DE SUS PROFARMACOS O UNA DE SUS SALES, ESTANDO EL AGENTE ACTIVO EN UNA CANTIDAD TOTAL TERAPEUTICAMENTE EFECTIVA Y DISPERSO EN UNA MATRIZ QUE COMPRENDE DE NADA A MENOS DE UNA CANTIDAD EFECTIVA QUE SOLUBILIZA UN AGENTE ACTIVO EN TOTAL DE UNO O MAS DISOLVENTES DIFERENTES DEL ADHESIVO. UN PROCEDIMIENTO DE TRATAMIENTO LOCAL DE UN SITIO DE DOLOR Y/O INFLAMACION EN UN SUJETO COMPRENDE LA APLICACION DE LA COMPOSICION SOBRE LA SUPERFICIE DE PIEL DEL SUJETO, PREFERIBLEMENTE EN UNA LOCALIZACION SUPERPUESTA O ADYACENTE AL SITIO DE DOLOR Y/O INFLAMACION, Y DEJANDO LA COMPOSICION EN EL LUGAR DURANTE UN PERIODO DE TIEMPO EFECTIVO PARA PERMITIR LA LIBERACION DE UNA CANTIDAD LOCALMENTE TERAPEUTICA DEL AGENTE ACTIVO. UN PROCEDIMIENTO DE TRATAMIENTO SISTEMICO DE UN SUJETO QUE TIENE UN TRASTORNO MEDIADO POR COX-2 COMPRENDE APLICAR LA COMPOSICION SOBRE UNA SUPERFIECIE DE PIEL DEL SUJETO, Y DEJAR LA COMPOSICION EN EL LUGAR DURANTE UN PERIODO DE TIEMPO EFCTIVO PARA PERMITIR LA LIBERACION TRANSDERMICA DE UNA CANTIDAD TERAPEUTICA DEL AGENTE ACTIVO.
PA20038589101A 2002-11-21 2003-11-19 Lamina revestida de adhesivo para administracion dermica de un inhibidor selectivo de ciclooxigenasa-2 PA8589101A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US42820802P 2002-11-21 2002-11-21

Publications (1)

Publication Number Publication Date
PA8589101A1 true PA8589101A1 (es) 2005-02-04

Family

ID=32393363

Family Applications (1)

Application Number Title Priority Date Filing Date
PA20038589101A PA8589101A1 (es) 2002-11-21 2003-11-19 Lamina revestida de adhesivo para administracion dermica de un inhibidor selectivo de ciclooxigenasa-2

Country Status (15)

Country Link
US (1) US20040127531A1 (es)
EP (1) EP1565169A1 (es)
JP (1) JP2006509761A (es)
AR (1) AR042104A1 (es)
AU (1) AU2003287732A1 (es)
BR (1) BR0316275A (es)
CA (1) CA2501287A1 (es)
GT (1) GT200300247A (es)
MX (1) MXPA05005510A (es)
NL (1) NL1024816C2 (es)
PA (1) PA8589101A1 (es)
PE (1) PE20040548A1 (es)
TW (1) TW200427471A (es)
UY (1) UY28087A1 (es)
WO (1) WO2004047815A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4283507B2 (ja) * 2002-08-02 2009-06-24 久光製薬株式会社 経皮投与用貼付剤
JP2007517013A (ja) * 2003-12-24 2007-06-28 ファルマシア コーポレーション 炎症、疼痛および／または発熱の治療を目的としたｃｏｘ−２阻害薬バルデコキシブのプロドラッグとしてのパレコキシブ金属塩
US7666914B2 (en) * 2004-06-03 2010-02-23 Richlin David M Topical preparation and method for transdermal delivery and localization of therapeutic agents
US20070259029A1 (en) * 2006-05-08 2007-11-08 Mcentire Edward Enns Water-dispersible patch containing an active agent for dermal delivery
US20070258935A1 (en) * 2006-05-08 2007-11-08 Mcentire Edward Enns Water dispersible films for delivery of active agents to the epidermis
US20080057090A1 (en) * 2006-09-01 2008-03-06 Mcentire Edward Enns Wrinkle masking film composition for skin
US7879942B2 (en) * 2006-10-05 2011-02-01 Eastman Chemical Company Switchable adhesive article for attachment to skin and method of using the same
US8445037B2 (en) * 2008-10-28 2013-05-21 A. M. Todd Company Volatile distillate by-product of mint oil that promotes absorption and/or bioavailability of compounds of bio-medical and nutritional interest
US8563031B2 (en) * 2010-05-27 2013-10-22 Absize, Inc. Piroxicam-containing matrix patches and methods for the topical treatment of acute and chronic pain and inflammation therewith
JP2012020991A (ja) * 2010-06-16 2012-02-02 Takasago Internatl Corp 経皮吸収促進剤、及びこれを含有する皮膚外用製剤
JP5285822B1 (ja) * 2012-12-19 2013-09-11 ニチバン株式会社 顔面用貼付材
US20160256407A1 (en) * 2013-10-11 2016-09-08 Xep, Inc. Energy patch
KR102042456B1 (ko) * 2018-03-22 2019-11-08 크리스탈지노믹스(주) 경피흡수제제

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69739003D1 (de) * 1996-04-12 2008-10-30 Searle Llc Substituierte Benzensulfonamid-Derivate als Wirkstoff-Vorläufer von COX-2 Inhibitoren
KR20000035801A (ko) * 1996-10-30 2000-06-26 에버트 챨스 디 침투증강제로써라틱산지방산에스테르염
ES2197077T3 (es) * 1999-03-01 2004-01-01 Amarin Technologies S.A. Dispositivo transdermico que comprende farmacos anti-inflamatorios no esteroides incorporados en una matriz de un polimero acrilico adhesivo.
US6309663B1 (en) * 1999-08-17 2001-10-30 Lipocine Inc. Triglyceride-free compositions and methods for enhanced absorption of hydrophilic therapeutic agents
IN191512B (es) * 2000-01-21 2003-12-06 Panacea Biotech
DE10032132A1 (de) * 2000-07-01 2002-01-17 Lohmann Therapie Syst Lts Dermales Therapeutisches System enthaltend nichtsteroidale Antiphlogistika mit selektiver COX-2-Hemmung
CZ20033241A3 (cs) * 2001-05-31 2004-08-18 Pharmaciaácorporation Kůži prostupující přípravek obsahující selektivně inhibující cyklooxygenázu@@ a jednosytný alkohol
JP4283507B2 (ja) * 2002-08-02 2009-06-24 久光製薬株式会社 経皮投与用貼付剤

Also Published As

Publication number Publication date
EP1565169A1 (en) 2005-08-24
US20040127531A1 (en) 2004-07-01
JP2006509761A (ja) 2006-03-23
AR042104A1 (es) 2005-06-08
BR0316275A (pt) 2005-10-04
AU2003287732A1 (en) 2004-06-18
MXPA05005510A (es) 2005-07-25
UY28087A1 (es) 2004-06-30
NL1024816A1 (nl) 2004-05-26
TW200427471A (en) 2004-12-16
PE20040548A1 (es) 2004-08-28
CA2501287A1 (en) 2004-06-10
WO2004047815A1 (en) 2004-06-10
NL1024816C2 (nl) 2006-03-06
GT200300247A (es) 2004-07-12

Similar Documents

Publication Publication Date Title
PA8589101A1 (es) Lamina revestida de adhesivo para administracion dermica de un inhibidor selectivo de ciclooxigenasa-2
NO20026171L (no) Topiske farmasöytiske formuleringer og fremgangsmåter for behandling
ATE434458T1 (de) Austragungsvorrichtungen für eine lokal begrenzte austragung eines pleurodesewirkstoffes
BRPI0509901A (pt) aparelho e método para liberação transdérmica de agentes com base em fentanila
BR9815378A (pt) Sistema de fornecimento de droga transdérmico para agente analgésico antiinflamatório compreendendo sal de dietilamÈnio diclofenac e o método de fabricação do mesmo.
AR046697A1 (es) Metodo y sistema de administracion transdermica de agente asistido por frecuencia
BRPI0415466A (pt) método e sistema de pré-tratamento para intensificar a distribuição transdérmica de fármacos
NO20034684D0 (no) Innretning for administrering av midler gjennom stratum corcum
AR042815A1 (es) Dispositivo de suministro de agente activo que tiene miembros compuestos
FI962770A0 (fi) Transdermaalinen laite, joka sisältää polyvinyylipyrrolidonia liukoisuutta parantavana aineena
WO2004078122A3 (en) Invisible patch for active agnet controlled delivery
BR0306513A (pt) tampão com medicamento
PA8589001A1 (es) Administracion dermica de un inhibidor de ciclooxigenasa-2 selectivo soluble en agua
BRPI0417437A (pt) dispositivo para inibição da absorção, dispositivo para remoção de agente fisiologicamente ativo e dispositivo para redução do efeito de overdose
BRPI0415986A (pt) método e aparelho para reduzir a incidência do uso de tabaco
BR0316436A (pt) Emplastro inibidor seletivo de ciclooxigenase-2
BRPI0415725A (pt) formulação aspergìvel transdérmica, método para administrar um agente farmaceuticamente ativo e método para formar uma pelìcula farmaceuticamente ativa
AR054225A1 (es) Aparato y metodo para suministro transdermico de agentes basados en epoyetina
HUP0003347A2 (hu) Transzdermális terápiás rendszer (TTS) hatóanyag leadásához és eljárás a bőrre történő alkalmazáshoz
DOP2003000759A (es) Lamina revestida de adhesivo para administracion dermica de un inhibidor selectivo de ciclooxigenasa-2
DOP2003000758A (es) Administracion dermica de un inhibidor de ciclooxigenasa-2 selectivo soluble en agua
ES2179658T3 (es) Uso de oxazolidinonas para la preparacion de un medicamento de suministro transdermico.
Parmar et al. Periodontal Gel For The Targeted Drug Delivery In The Periodontal Cavity For Management Of Periodontitis And Gingivitis
YU71293A (sh) Transdermalni terapijski sistem za davanje fizostigmina na koži i postupak za njegovu izradu
JP3197332U (ja) 皮膚の痒み止め用貼付剤