AR042104A1 - Lamina revestida de adhesivo para administracion dermica de un inhibidor selectivo de ciclooxigenasa -2 - Google Patents
Lamina revestida de adhesivo para administracion dermica de un inhibidor selectivo de ciclooxigenasa -2Info
- Publication number
- AR042104A1 AR042104A1 ARP030104296A ARP030104296A AR042104A1 AR 042104 A1 AR042104 A1 AR 042104A1 AR P030104296 A ARP030104296 A AR P030104296A AR P030104296 A ARP030104296 A AR P030104296A AR 042104 A1 AR042104 A1 AR 042104A1
- Authority
- AR
- Argentina
- Prior art keywords
- active agent
- subject
- composition
- skin
- amount
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7007—Drug-containing films, membranes or sheets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Materials For Medical Uses (AREA)
Abstract
Composición farmacéutica para la aplicación sobre un área de piel de un sujeto para tratamiento local y/o sistémico de un trastorno mediado por COX-2 que comprende una lámina de soporte que se puede adaptar flexiblemente al área de piel, teniendo la lámina de soporte superficies opuestas que son respectivamente distales y proximales a la piel cuando se aplica; y un revestimiento sobre la superficie proximal de la lámina de soporte que comprende (a) un adhesivo y (b) un agente activo que comprende valdecoxib o uno de sus profármacos o una de sus sales, estando el agente activo en una cantidad total terapéuticamente efectiva y disperso en una matriz que comprende de nada a menos de una cantidad efectiva que solubiliza un agente activo en total de uno o más disolventes diferentes del adhesivo. Un procedimiento de tratamiento local de un sitio de dolor y/o inflamación en un sujeto comprende la aplicación de la composición sobre la superficie de piel del sujeto, preferiblemente en una localización superpuesta o adyacente al sitio de dolor y/o inflamación, y dejando la composición en el lugar durante un período de tiempo efectivo para permitir la liberación de una cantidad localmente terapéutica del agente activo. Un procedimiento de tratamiento sistémico de un sujeto que tiene un trastorno mediado por COX-2 comprende aplicar la composición sobre una superficie de piel del sujeto, y dejar la composición en el lugar durante un período de tiempo efectivo para permitir la liberación transdémica de una cantidad terapéutica del agente activo.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42820802P | 2002-11-21 | 2002-11-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR042104A1 true AR042104A1 (es) | 2005-06-08 |
Family
ID=32393363
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP030104296A AR042104A1 (es) | 2002-11-21 | 2003-11-20 | Lamina revestida de adhesivo para administracion dermica de un inhibidor selectivo de ciclooxigenasa -2 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20040127531A1 (es) |
| EP (1) | EP1565169A1 (es) |
| JP (1) | JP2006509761A (es) |
| AR (1) | AR042104A1 (es) |
| AU (1) | AU2003287732A1 (es) |
| BR (1) | BR0316275A (es) |
| CA (1) | CA2501287A1 (es) |
| GT (1) | GT200300247A (es) |
| MX (1) | MXPA05005510A (es) |
| NL (1) | NL1024816C2 (es) |
| PA (1) | PA8589101A1 (es) |
| PE (1) | PE20040548A1 (es) |
| TW (1) | TW200427471A (es) |
| UY (1) | UY28087A1 (es) |
| WO (1) | WO2004047815A1 (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4283507B2 (ja) * | 2002-08-02 | 2009-06-24 | 久光製薬株式会社 | 経皮投与用貼付剤 |
| JP2007517013A (ja) * | 2003-12-24 | 2007-06-28 | ファルマシア コーポレーション | 炎症、疼痛および／または発熱の治療を目的としたｃｏｘ−２阻害薬バルデコキシブのプロドラッグとしてのパレコキシブ金属塩 |
| US7666914B2 (en) * | 2004-06-03 | 2010-02-23 | Richlin David M | Topical preparation and method for transdermal delivery and localization of therapeutic agents |
| US20070258935A1 (en) * | 2006-05-08 | 2007-11-08 | Mcentire Edward Enns | Water dispersible films for delivery of active agents to the epidermis |
| US20070259029A1 (en) * | 2006-05-08 | 2007-11-08 | Mcentire Edward Enns | Water-dispersible patch containing an active agent for dermal delivery |
| US20080057090A1 (en) * | 2006-09-01 | 2008-03-06 | Mcentire Edward Enns | Wrinkle masking film composition for skin |
| US7879942B2 (en) * | 2006-10-05 | 2011-02-01 | Eastman Chemical Company | Switchable adhesive article for attachment to skin and method of using the same |
| US8445037B2 (en) * | 2008-10-28 | 2013-05-21 | A. M. Todd Company | Volatile distillate by-product of mint oil that promotes absorption and/or bioavailability of compounds of bio-medical and nutritional interest |
| US8563031B2 (en) * | 2010-05-27 | 2013-10-22 | Absize, Inc. | Piroxicam-containing matrix patches and methods for the topical treatment of acute and chronic pain and inflammation therewith |
| JP2012020991A (ja) * | 2010-06-16 | 2012-02-02 | Takasago Internatl Corp | 経皮吸収促進剤、及びこれを含有する皮膚外用製剤 |
| WO2014097422A1 (ja) * | 2012-12-19 | 2014-06-26 | ニチバン株式会社 | 顔面用貼付材 |
| US20160256407A1 (en) * | 2013-10-11 | 2016-09-08 | Xep, Inc. | Energy patch |
| BR112020005967A2 (pt) * | 2017-09-27 | 2020-10-06 | Aquestive Therapeutics, Inc. | composições farmacêuticas com permeação realçada |
| KR102042456B1 (ko) * | 2018-03-22 | 2019-11-08 | 크리스탈지노믹스(주) | 경피흡수제제 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0892791B1 (en) * | 1996-04-12 | 2003-03-05 | G.D. Searle & Co. | N-[[4-(5-METHYL-3-PHENYLISOXAZOL-4-YL]PHENYL]SULFONYLPROPYLAMIDE and its SODIUMSALT AS PRODRUGS OF COX-2 INHIBITORS |
| WO1998018416A1 (en) * | 1996-10-30 | 1998-05-07 | Theratech, Inc. | Fatty acid esters of glycolic acid and its salts as permeation enhancers |
| ES2197077T3 (es) * | 1999-03-01 | 2004-01-01 | Amarin Technologies S.A. | Dispositivo transdermico que comprende farmacos anti-inflamatorios no esteroides incorporados en una matriz de un polimero acrilico adhesivo. |
| US6309663B1 (en) * | 1999-08-17 | 2001-10-30 | Lipocine Inc. | Triglyceride-free compositions and methods for enhanced absorption of hydrophilic therapeutic agents |
| IN191512B (es) * | 2000-01-21 | 2003-12-06 | Panacea Biotech | |
| DE10032132A1 (de) * | 2000-07-01 | 2002-01-17 | Lohmann Therapie Syst Lts | Dermales Therapeutisches System enthaltend nichtsteroidale Antiphlogistika mit selektiver COX-2-Hemmung |
| TNSN03127A1 (fr) * | 2001-05-31 | 2005-12-23 | Pharmacia Corp | Composition d'inhibiteur de cyclo-oxygenase-2-selectif, apte a la penetration dermique |
| JP4283507B2 (ja) * | 2002-08-02 | 2009-06-24 | 久光製薬株式会社 | 経皮投与用貼付剤 |
-
2003
- 2003-10-28 US US10/695,025 patent/US20040127531A1/en not_active Abandoned
- 2003-11-12 AU AU2003287732A patent/AU2003287732A1/en not_active Abandoned
- 2003-11-12 WO PCT/US2003/036362 patent/WO2004047815A1/en not_active Application Discontinuation
- 2003-11-12 CA CA002501287A patent/CA2501287A1/en not_active Abandoned
- 2003-11-12 BR BR0316275-3A patent/BR0316275A/pt not_active IP Right Cessation
- 2003-11-12 JP JP2004555449A patent/JP2006509761A/ja not_active Withdrawn
- 2003-11-12 MX MXPA05005510A patent/MXPA05005510A/es unknown
- 2003-11-12 EP EP03781939A patent/EP1565169A1/en not_active Withdrawn
- 2003-11-19 PA PA20038589101A patent/PA8589101A1/es unknown
- 2003-11-19 NL NL1024816A patent/NL1024816C2/nl not_active IP Right Cessation
- 2003-11-20 TW TW092132571A patent/TW200427471A/zh unknown
- 2003-11-20 PE PE2003001177A patent/PE20040548A1/es not_active Application Discontinuation
- 2003-11-20 GT GT200300247A patent/GT200300247A/es unknown
- 2003-11-20 AR ARP030104296A patent/AR042104A1/es unknown
- 2003-11-21 UY UY28087A patent/UY28087A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NL1024816A1 (nl) | 2004-05-26 |
| WO2004047815A1 (en) | 2004-06-10 |
| CA2501287A1 (en) | 2004-06-10 |
| TW200427471A (en) | 2004-12-16 |
| US20040127531A1 (en) | 2004-07-01 |
| EP1565169A1 (en) | 2005-08-24 |
| PE20040548A1 (es) | 2004-08-28 |
| PA8589101A1 (es) | 2005-02-04 |
| JP2006509761A (ja) | 2006-03-23 |
| BR0316275A (pt) | 2005-10-04 |
| UY28087A1 (es) | 2004-06-30 |
| NL1024816C2 (nl) | 2006-03-06 |
| AU2003287732A1 (en) | 2004-06-18 |
| GT200300247A (es) | 2004-07-12 |
| MXPA05005510A (es) | 2005-07-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |