PA8589001A1 - Administracion dermica de un inhibidor de ciclooxigenasa-2 selectivo soluble en agua - Google Patents
Administracion dermica de un inhibidor de ciclooxigenasa-2 selectivo soluble en aguaInfo
- Publication number
- PA8589001A1 PA8589001A1 PA20038589001A PA8589001A PA8589001A1 PA 8589001 A1 PA8589001 A1 PA 8589001A1 PA 20038589001 A PA20038589001 A PA 20038589001A PA 8589001 A PA8589001 A PA 8589001A PA 8589001 A1 PA8589001 A1 PA 8589001A1
- Authority
- PA
- Panama
- Prior art keywords
- composition
- subject
- active agent
- cox
- administration
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
UNA COMPOSICION FARMACEUTICA PARA APLICACION A UN AREA DE PIEL DE UN SUJETO PARA EL TRATAMIENTO LOCAL Y/O SISTEMICO DE UN TRASTORNO MEDIADO POR COX-2, QUE COMPRENDE UNA LAMINA DE SOPORTE QUE PUEDE CONFORMARSE DE FORMA FLEXIBLE AL AREA DE PIEL, TENIENDO LA LAMINA DE SOPORTE SUPERFICIES ENFRENTADAS QUE ESTAN RESPECTIVAMENTE DISTAL Y PROXIMAL A LA PIEL CUANDO SE APLICA; Y UN RECUBRIMIENTO SOBRE LA SUPERFICIE PROXIMAL DE LA LAMINA DE SOPORTE, QUE COMPRNDE (a) UN ADHESIVO Y (B) UN AGENTE ACTIVO SOLUBLE EN AGUA SELECCIONADO DE FARMACOS O PROFARMACOS O SUS SALES INHIBIDORES DE COX-2 SELECTIVOS, ESTANDO EL AGENTE ACTIVO EN UNA CANTIDAD TOTAL TERAPEUTICAMENTE EFECTIVA Y DISPERSO EN UNA MATRIZ QUE COMPRENDE DE CERO A MENOS DE UNA CANTIDAD EFECTIVA PARA SOLUBILIZAR EL AGENTE ACTIVO EN TOTAL DE UNO O MAS DISOLVENTES DISTINTOS DEL ADHESIVO. UN PROCEDIMIENTO DE TRATAMIENTO LOCAL DE UN SITIO DE DOLOR Y/O INFLAMACION QUE COMPRENDE APLICAR LA COMPOSICION A UNA SUPERFICIE DE PIEL DEL SUJETO, PREFERIBLEMENTE EN UNA LOCALIZACION POR ENCIMA O ADYACENTE AL SITIO DE DOLOR Y/O INFLAMACION, Y DEJAR LA COMPOSICION COLOCADA DURANTE UN PERIODO DE TIEMPO EFECTIVO PARA PERMITIR LA ADMINISTRACION DE UNA CANTIDAD LOCALMENTE TERAPEUTICA DEL AGENTE ACTIVO. UN PROCEDIMIENTO DE TRATAMIENTO SISTEMICO DE UN SUJETO QUE TIENE UN TRASTORNO MEDIADO POR COX-2, QUE COMPRENDE APLICAR LA COMPOSICION A UNA SUPERFICIE DE PIEL DEL SUJETO, Y DEJAR LA COMPOSICION COLOCADA DURANTE UN PERIODO DE TIEMPO EFECTIVO PARA PERMITIR LA ADMINISTRACION TRANSDERMICA DE UNA CANTIDAD TERAPEUTICA DEL AGENTE ACTIVO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US42820102P | 2002-11-21 | 2002-11-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
PA8589001A1 true PA8589001A1 (es) | 2005-02-04 |
Family
ID=32393362
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PA20038589001A PA8589001A1 (es) | 2002-11-21 | 2003-11-19 | Administracion dermica de un inhibidor de ciclooxigenasa-2 selectivo soluble en agua |
Country Status (15)
Country | Link |
---|---|
US (1) | US20040126415A1 (es) |
EP (1) | EP1572166A1 (es) |
JP (1) | JP2006509759A (es) |
AR (1) | AR042102A1 (es) |
AU (1) | AU2003291386A1 (es) |
BR (1) | BR0316463A (es) |
CA (1) | CA2506628A1 (es) |
GT (1) | GT200300249A (es) |
MX (1) | MXPA05004989A (es) |
NL (1) | NL1024830C2 (es) |
PA (1) | PA8589001A1 (es) |
PE (1) | PE20041026A1 (es) |
TW (1) | TW200503787A (es) |
UY (1) | UY28086A1 (es) |
WO (1) | WO2004047814A1 (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7943166B2 (en) | 2003-04-10 | 2011-05-17 | Neurogesx, Inc. | Methods and compositions for administration of TRPV1 agonists |
US7666914B2 (en) * | 2004-06-03 | 2010-02-23 | Richlin David M | Topical preparation and method for transdermal delivery and localization of therapeutic agents |
KR20070121666A (ko) * | 2005-02-14 | 2007-12-27 | 노이로제스엑스, 인코포레이티드 | Trpv1 작용제의 전달용 장치 |
EP1865933B1 (en) * | 2005-03-30 | 2015-11-04 | Vanderbilt Royalty Sub L.P. | Low-concentration capsaicin patch and methods for treating neuropathic pain |
DE102005050431A1 (de) * | 2005-10-21 | 2007-04-26 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System zur Verabreicherung lipophiler und/oder wenig hautpermeabler Wirkstoffe |
WO2007133514A2 (en) * | 2006-05-10 | 2007-11-22 | Ceramoptec Industries, Inc. | Photosensitizer formulations for topical applications |
DE102006054732B4 (de) * | 2006-11-21 | 2010-12-30 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System mit Ionenpaar-Mikroreservoiren |
JP4327841B2 (ja) * | 2006-12-20 | 2009-09-09 | 日東電工株式会社 | 経皮吸収製剤の製造装置および製造方法 |
US20090291140A1 (en) * | 2008-05-21 | 2009-11-26 | Andrew Korey | Treatment of dysmenorrhea via transdermal administration of nonsteroidal anti-inflammatory drugs |
JP2012020991A (ja) * | 2010-06-16 | 2012-02-02 | Takasago Internatl Corp | 経皮吸収促進剤、及びこれを含有する皮膚外用製剤 |
US9814911B2 (en) * | 2011-07-15 | 2017-11-14 | Robert Benson Aylor | Skin and hair treatments |
CA2966843A1 (en) * | 2014-11-10 | 2016-05-19 | Achelios Therapeutics, Inc. | Sprayable analgesic compositions |
KR102042456B1 (ko) * | 2018-03-22 | 2019-11-08 | 크리스탈지노믹스(주) | 경피흡수제제 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0892791B1 (en) * | 1996-04-12 | 2003-03-05 | G.D. Searle & Co. | N-[[4-(5-METHYL-3-PHENYLISOXAZOL-4-YL]PHENYL]SULFONYLPROPYLAMIDE and its SODIUMSALT AS PRODRUGS OF COX-2 INHIBITORS |
CN1231592A (zh) * | 1996-10-30 | 1999-10-13 | 瑟垃技术有限公司 | 作为渗透促进剂的羟乙酸及其盐的脂肪酸酯 |
CA2366852A1 (en) * | 1999-03-01 | 2000-09-08 | Alejandro Fabio Scasso | Transdermal device comprising non-steroidal anti-inflammatory drugs incorporated in acrylic adhesive polymer matrix |
US6309663B1 (en) * | 1999-08-17 | 2001-10-30 | Lipocine Inc. | Triglyceride-free compositions and methods for enhanced absorption of hydrophilic therapeutic agents |
IN191512B (es) * | 2000-01-21 | 2003-12-06 | Panacea Biotech | |
DE10032132A1 (de) * | 2000-07-01 | 2002-01-17 | Lohmann Therapie Syst Lts | Dermales Therapeutisches System enthaltend nichtsteroidale Antiphlogistika mit selektiver COX-2-Hemmung |
AU2002306868A1 (en) * | 2001-03-28 | 2002-10-15 | Pharmacia Corporation | Therapeutic combinations for cardiovascular and inflammatory indications |
CA2448627A1 (en) * | 2001-05-31 | 2002-12-05 | Pharmacia Corporation | Skin-permeable composition comprising a selective cyclooxygenase-2 inhibitor a monohydric alcohol |
JP4283507B2 (ja) * | 2002-08-02 | 2009-06-24 | 久光製薬株式会社 | 経皮投与用貼付剤 |
-
2003
- 2003-10-10 US US10/683,943 patent/US20040126415A1/en not_active Abandoned
- 2003-11-07 EP EP03768780A patent/EP1572166A1/en not_active Withdrawn
- 2003-11-07 BR BR0316463-2A patent/BR0316463A/pt not_active IP Right Cessation
- 2003-11-07 MX MXPA05004989A patent/MXPA05004989A/es unknown
- 2003-11-07 CA CA002506628A patent/CA2506628A1/en not_active Abandoned
- 2003-11-07 WO PCT/US2003/035638 patent/WO2004047814A1/en not_active Application Discontinuation
- 2003-11-07 JP JP2004555394A patent/JP2006509759A/ja not_active Withdrawn
- 2003-11-07 AU AU2003291386A patent/AU2003291386A1/en not_active Abandoned
- 2003-11-19 PA PA20038589001A patent/PA8589001A1/es unknown
- 2003-11-20 NL NL1024830A patent/NL1024830C2/nl not_active IP Right Cessation
- 2003-11-20 AR ARP030104294A patent/AR042102A1/es unknown
- 2003-11-20 TW TW092132570A patent/TW200503787A/zh unknown
- 2003-11-20 GT GT200300249A patent/GT200300249A/es unknown
- 2003-11-21 PE PE2003001182A patent/PE20041026A1/es not_active Application Discontinuation
- 2003-11-21 UY UY28086A patent/UY28086A1/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
NL1024830C2 (nl) | 2006-03-06 |
JP2006509759A (ja) | 2006-03-23 |
WO2004047814A1 (en) | 2004-06-10 |
NL1024830A1 (nl) | 2004-05-26 |
PE20041026A1 (es) | 2005-02-05 |
AR042102A1 (es) | 2005-06-08 |
UY28086A1 (es) | 2004-06-30 |
AU2003291386A1 (en) | 2004-06-18 |
TW200503787A (en) | 2005-02-01 |
GT200300249A (es) | 2004-07-12 |
EP1572166A1 (en) | 2005-09-14 |
BR0316463A (pt) | 2005-10-11 |
US20040126415A1 (en) | 2004-07-01 |
CA2506628A1 (en) | 2004-06-10 |
MXPA05004989A (es) | 2005-08-02 |
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