BRPI0416132A - sistema e método para liberação de vacina transdérmica - Google Patents

sistema e método para liberação de vacina transdérmica

Info

Publication number
BRPI0416132A
BRPI0416132A BRPI0416132-7A BRPI0416132A BRPI0416132A BR PI0416132 A BRPI0416132 A BR PI0416132A BR PI0416132 A BRPI0416132 A BR PI0416132A BR PI0416132 A BRPI0416132 A BR PI0416132A
Authority
BR
Brazil
Prior art keywords
microprojections
vaccine
transdermal
iontophoresis
electrode
Prior art date
Application number
BRPI0416132-7A
Other languages
English (en)
Inventor
Janardhanan Subramony
Joseph B Phipps
Michel J N Cormier
Georg Widera
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of BRPI0416132A publication Critical patent/BRPI0416132A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/20—Surgical instruments, devices or methods, e.g. tourniquets for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205—Vaccinating by means of needles or other puncturing devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00743—Type of operation; Specification of treatment sites
    • A61B2017/00747—Dermatology
    • A61B2017/00765—Decreasing the barrier function of skin tissue by radiated energy, e.g. using ultrasound, using laser for skin perforation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Electrotherapy Devices (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

"SISTEMA E MéTODO PARA LIBERAçãO, DE VACINA TRANSDéRMICA". Um sistema e método para liberar transdermicamente uma vacina para um paciente, incluindo um dispositivo de liberação de iontoforese que tem um eletrodo doador, um contra-eletrodo, e circuito elétrico para suprir energia de iontoforese para os eletrodos, e um membro de microprojeção não eletroativo que possui uma pluralidade de microprojeções que penetram o estrato córneo estendendo-se a partir dele. A vacina pode estar contida em uma formulação de hidrogel em um reservatório de agente disposto próximo ao eletrodo doador, em um revestimento biocompatível que é disposto sobre as microprojeções ou em ambos.
BRPI0416132-7A 2003-10-31 2004-10-21 sistema e método para liberação de vacina transdérmica BRPI0416132A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51618403P 2003-10-31 2003-10-31
PCT/US2004/034924 WO2005044366A2 (en) 2003-10-31 2004-10-21 System and method for transdermal vaccine delivery

Publications (1)

Publication Number Publication Date
BRPI0416132A true BRPI0416132A (pt) 2007-01-02

Family

ID=34572873

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0416132-7A BRPI0416132A (pt) 2003-10-31 2004-10-21 sistema e método para liberação de vacina transdérmica

Country Status (11)

Country Link
US (1) US20050123565A1 (pt)
EP (1) EP1680178A4 (pt)
JP (1) JP2007509704A (pt)
KR (1) KR20060127394A (pt)
CN (1) CN1897920A (pt)
AR (1) AR046922A1 (pt)
AU (1) AU2004287411A1 (pt)
BR (1) BRPI0416132A (pt)
CA (1) CA2543639A1 (pt)
TW (1) TW200528153A (pt)
WO (1) WO2005044366A2 (pt)

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JP2007503268A (ja) * 2003-08-25 2007-02-22 スリーエム イノベイティブ プロパティズ カンパニー 免疫応答修飾化合物の送達
IL159273A0 (en) * 2003-12-09 2004-06-01 Transpharma Medical Ltd Transdermal delivery system for sustained release of polypeptides
WO2006003659A2 (en) * 2004-07-06 2006-01-12 Transpharma Medical Ltd. Delivery system for transdermal immunization
US8048017B2 (en) 2005-05-18 2011-11-01 Bai Xu High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances
CN101189030A (zh) * 2005-06-02 2008-05-28 阿尔扎公司 透皮递送器械的最终消毒方法
WO2006130869A1 (en) * 2005-06-02 2006-12-07 Alza Corporation Method for terminal sterilization of transdermal delivery devices
WO2006131931A2 (en) * 2005-06-10 2006-12-14 Transpharma Medical, Ltd. Patch for transdermal drug delivery
US20070009542A1 (en) * 2005-07-05 2007-01-11 Galit Levin Method and device for transdermal immunization
AU2006291157A1 (en) * 2005-09-12 2007-03-22 Alza Corporation Coatable transdermal delivery microprojection assembly
US20070185432A1 (en) * 2005-09-19 2007-08-09 Transport Pharmaceuticals, Inc. Electrokinetic system and method for delivering methotrexate
US20070083185A1 (en) * 2005-09-30 2007-04-12 Darrick Carter Iontophoretic device and method of delivery of active agents to biological interface
EP1948139A4 (en) * 2005-11-18 2012-04-04 3M Innovative Properties Co COATING COMPOSITIONS, COATINGS DERIVED THEREFROM, AND MICRO-NETWORKS COMPRISING SUCH COATINGS
US7848801B2 (en) * 2005-12-30 2010-12-07 Tti Ellebeau, Inc. Iontophoretic systems, devices, and methods of delivery of active agents to biological interface
EA200870252A1 (ru) * 2006-02-11 2009-02-27 Дженетроникс, Инк. Устройство и способ одноигольного электропорообразования in vivo
US20080287857A1 (en) * 2006-02-11 2008-11-20 Rune Kjeken Device and method for single-needle in vivo electroporation
EP2005990B1 (en) * 2006-04-07 2013-08-28 Hisamitsu Pharmaceutical Co., Inc. Microneedle device and transdermal administration device provided with microneedles
US7687103B2 (en) * 2006-08-31 2010-03-30 Gamida For Life B.V. Compositions and methods for preserving permeation layers for use on active electronic matrix devices
US10525246B2 (en) 2006-12-22 2020-01-07 Nanomed Skincare, Inc. Microdevice and method for transdermal delivery and sampling of active substances
US20080214987A1 (en) 2006-12-22 2008-09-04 Nanomed Devices, Inc. Microdevice And Method For Transdermal Delivery And Sampling Of Active Substances
WO2008139648A1 (ja) * 2007-05-15 2008-11-20 Hisamitsu Pharmaceutical Co., Inc. マイクロニードルのコーティング方法
US20090082713A1 (en) * 2007-09-20 2009-03-26 Friden Phillip M Method of enhancing iontophoretic delivery of a peptide
WO2009047365A1 (en) * 2007-10-12 2009-04-16 Capsulution Nanoscience Ag Drug delivery system
WO2009057112A2 (en) * 2007-10-29 2009-05-07 Transpharma Medical, Ltd. Vertical patch drying
CA2729404C (en) 2008-06-30 2016-09-27 Hisamitsu Pharmaceutical Co., Inc. Microneedle device and method for enhancing the efficacy of influenza vaccine using microneedle device
US8606366B2 (en) 2009-02-18 2013-12-10 Syneron Medical Ltd. Skin treatment apparatus for personal use and method for using same
US8781576B2 (en) 2009-03-17 2014-07-15 Cardiothrive, Inc. Device and method for reducing patient transthoracic impedance for the purpose of delivering a therapeutic current
EP2408521B1 (en) * 2009-03-17 2014-06-25 Cardio Thrive, Inc External defibrillator
ES2691259T3 (es) 2009-06-10 2018-11-26 Hisamitsu Pharmaceutical Co., Inc. Dispositivo de microagujas
EP2457592B1 (en) 2009-07-23 2020-09-16 Hisamitsu Pharmaceutical Co., Inc. Microneedle array
US8512679B2 (en) 2011-03-04 2013-08-20 Elwha Llc Glassy compositions
JP6170906B2 (ja) 2011-04-21 2017-07-26 トラスティーズ・オブ・タフツ・カレッジＴｒｕｓｔｅｅｓ Ｏｆ Ｔｕｆｔｓ Ｃｏｌｌｅｇｅ 活性物質を安定化させるための組成物および方法
US9913978B2 (en) * 2011-06-28 2018-03-13 Kate Broderick Miniminally invasive dermal electroporation device
US9844592B2 (en) 2011-07-18 2017-12-19 Icahn School Of Medicine At Mount Sinai Bacterial RNAs as vaccine adjuvants
US10149973B2 (en) 2013-06-14 2018-12-11 Cardiothrive, Inc. Multipart non-uniform patient contact interface and method of use
US9616243B2 (en) 2013-06-14 2017-04-11 Cardiothrive, Inc. Dynamically adjustable multiphasic defibrillator pulse system and method
US9907970B2 (en) 2013-06-14 2018-03-06 Cardiothrive, Inc. Therapeutic system and method using biphasic or multiphasic pulse waveform
US10279189B2 (en) 2013-06-14 2019-05-07 Cardiothrive, Inc. Wearable multiphasic cardioverter defibrillator system and method
US9833630B2 (en) 2013-06-14 2017-12-05 Cardiothrive, Inc. Biphasic or multiphasic pulse waveform and method
US9656094B2 (en) 2013-06-14 2017-05-23 Cardiothrive, Inc. Biphasic or multiphasic pulse generator and method
FR3024368A1 (fr) * 2014-07-29 2016-02-05 Oreal Dispositif d'iontophorese a embout multi-electrodes
JP2019526611A (ja) 2016-09-13 2019-09-19 アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ 非タンパク質クロストリジウム毒素組成物
WO2018053524A1 (en) 2016-09-19 2018-03-22 Vaxess Technologies, Inc. Vaccine formulations with increased stability
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CN110404161A (zh) * 2019-09-10 2019-11-05 中山大学 一种基于微针式离子泳器件的透皮精确给药装置及其制备方法
US11904126B2 (en) * 2020-08-28 2024-02-20 City University Of Hong Kong Cryo formulation-based microneedle device for transdermal delivery of bioactive therapeutic agents and performing vaccination using a cryo-microneedle patch

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Also Published As

Publication number Publication date
EP1680178A2 (en) 2006-07-19
US20050123565A1 (en) 2005-06-09
AR046922A1 (es) 2006-01-04
WO2005044366A2 (en) 2005-05-19
TW200528153A (en) 2005-09-01
CA2543639A1 (en) 2005-05-19
WO2005044366A3 (en) 2006-03-16
KR20060127394A (ko) 2006-12-12
JP2007509704A (ja) 2007-04-19
CN1897920A (zh) 2007-01-17
AU2004287411A1 (en) 2005-05-19
EP1680178A4 (en) 2008-01-02

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A,6A E 7A ANUIDADE(S)

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2129 DE 25/10/2011.