BR0114909A - Dispositivos de distribuição de drogas transdérmicas possuindo microprotuberâncias revestidas - Google Patents

Dispositivos de distribuição de drogas transdérmicas possuindo microprotuberâncias revestidas

Info

Publication number
BR0114909A
BR0114909A BR0114909-1A BR0114909A BR0114909A BR 0114909 A BR0114909 A BR 0114909A BR 0114909 A BR0114909 A BR 0114909A BR 0114909 A BR0114909 A BR 0114909A
Authority
BR
Brazil
Prior art keywords
agent
drug delivery
delivery devices
transdermal drug
microprotrusions
Prior art date
Application number
BR0114909-1A
Other languages
English (en)
Inventor
Michel J N Cormier
Wendy A Young
Kofi Nyam
Peter E Daddona
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of BR0114909A publication Critical patent/BR0114909A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0061—Methods for using microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

"DISPOSITIVOS DE DISTRIBUIçãO DE DROGAS TRANSDéRMICAS POSSUINDO MICROPROTUBERâNCIAS REVESTIDAS". Um dispositivo (12) e método são fornecidos para a distribuição transdérmica percutânea de um agente farmacologicamente ativo potente. O agente é dissolvido em água para formar uma solução de revestimento aquosa possuindo uma viscosidade adequada para revestir elementos de perfuração de pele extremamente pequenos (10). A solução de revestimento é aplicada aos elementos de perfuração de pele (10) utilizando-se técnicas de revestimento conhecidas e então secas. O dispositivo (12) é aplicado na pele de uma animal vivo (por exemplo, um ser humano), causando as microprotuberâncias (10) para penetrar o extrato córneo e distribuir uma dose terapeuticamente eficaz do agente ao animal.
BR0114909-1A 2000-10-26 2001-10-26 Dispositivos de distribuição de drogas transdérmicas possuindo microprotuberâncias revestidas BR0114909A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24403800P 2000-10-26 2000-10-26
PCT/US2001/051496 WO2002094368A1 (en) 2000-10-26 2001-10-26 Transdermal drug delivery devices having coated microprotrusions

Publications (1)

Publication Number Publication Date
BR0114909A true BR0114909A (pt) 2004-02-03

Family

ID=22921144

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0114909-1A BR0114909A (pt) 2000-10-26 2001-10-26 Dispositivos de distribuição de drogas transdérmicas possuindo microprotuberâncias revestidas

Country Status (24)

Country Link
US (2) US7537795B2 (pt)
EP (2) EP1333880B1 (pt)
JP (2) JP4659336B2 (pt)
KR (1) KR100812097B1 (pt)
CN (1) CN1239212C (pt)
AT (1) ATE428466T1 (pt)
AU (1) AU2001297823B2 (pt)
BR (1) BR0114909A (pt)
CA (1) CA2427381A1 (pt)
CZ (1) CZ20031164A3 (pt)
DE (1) DE60138407D1 (pt)
DK (1) DK1333880T3 (pt)
ES (1) ES2322023T3 (pt)
HU (1) HUP0302924A2 (pt)
IL (1) IL155583A0 (pt)
MA (1) MA26061A1 (pt)
MX (1) MXPA03003815A (pt)
NO (1) NO20031875L (pt)
NZ (1) NZ525551A (pt)
PL (1) PL365677A1 (pt)
PT (1) PT1333880E (pt)
RU (1) RU2282468C2 (pt)
WO (1) WO2002094368A1 (pt)
ZA (1) ZA200303988B (pt)

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