DK1333880T3 - Indretninger med coatede mikrofremspring til medikamentafgivelse gennem huden - Google Patents
Indretninger med coatede mikrofremspring til medikamentafgivelse gennem hudenInfo
- Publication number
- DK1333880T3 DK1333880T3 DK01273947T DK01273947T DK1333880T3 DK 1333880 T3 DK1333880 T3 DK 1333880T3 DK 01273947 T DK01273947 T DK 01273947T DK 01273947 T DK01273947 T DK 01273947T DK 1333880 T3 DK1333880 T3 DK 1333880T3
- Authority
- DK
- Denmark
- Prior art keywords
- skin
- devices
- drug delivery
- coated micro
- pharmacologically active
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0023—Drug applicators using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0046—Solid microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0061—Methods for using microneedles
Landscapes
- Health & Medical Sciences (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Medical Informatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Vascular Medicine (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24403800P | 2000-10-26 | 2000-10-26 | |
PCT/US2001/051496 WO2002094368A1 (en) | 2000-10-26 | 2001-10-26 | Transdermal drug delivery devices having coated microprotrusions |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1333880T3 true DK1333880T3 (da) | 2009-07-20 |
Family
ID=22921144
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK01273947T DK1333880T3 (da) | 2000-10-26 | 2001-10-26 | Indretninger med coatede mikrofremspring til medikamentafgivelse gennem huden |
Country Status (24)
Country | Link |
---|---|
US (2) | US7537795B2 (da) |
EP (2) | EP1333880B1 (da) |
JP (2) | JP4659336B2 (da) |
KR (1) | KR100812097B1 (da) |
CN (1) | CN1239212C (da) |
AT (1) | ATE428466T1 (da) |
AU (1) | AU2001297823B2 (da) |
BR (1) | BR0114909A (da) |
CA (1) | CA2427381A1 (da) |
CZ (1) | CZ20031164A3 (da) |
DE (1) | DE60138407D1 (da) |
DK (1) | DK1333880T3 (da) |
ES (1) | ES2322023T3 (da) |
HU (1) | HUP0302924A2 (da) |
IL (1) | IL155583A0 (da) |
MA (1) | MA26061A1 (da) |
MX (1) | MXPA03003815A (da) |
NO (1) | NO20031875L (da) |
NZ (1) | NZ525551A (da) |
PL (1) | PL365677A1 (da) |
PT (1) | PT1333880E (da) |
RU (1) | RU2282468C2 (da) |
WO (1) | WO2002094368A1 (da) |
ZA (1) | ZA200303988B (da) |
Families Citing this family (149)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2195151T3 (es) * | 1996-06-18 | 2003-12-01 | Alza Corp | Dispositivo de mejora de aporte o de muestreo de agentes transdermicos. |
US6918901B1 (en) * | 1997-12-10 | 2005-07-19 | Felix Theeuwes | Device and method for enhancing transdermal agent flux |
CN100421653C (zh) * | 2000-09-08 | 2008-10-01 | 阿尔扎公司 | 通过抑制通道关闭来抑制药物透皮通量减少的方法 |
JP4659332B2 (ja) * | 2000-10-13 | 2011-03-30 | アルザ・コーポレーシヨン | 微小突起を用いて皮膚を穿孔するための装置および方法 |
RU2278623C2 (ru) * | 2000-10-13 | 2006-06-27 | Алза Корпорейшн | Держатель микровыступающего элемента для силового аппликатора |
US7419481B2 (en) * | 2000-10-13 | 2008-09-02 | Alza Corporation | Apparatus and method for piercing skin with microprotrusions |
US6855372B2 (en) * | 2001-03-16 | 2005-02-15 | Alza Corporation | Method and apparatus for coating skin piercing microprojections |
US20020193729A1 (en) * | 2001-04-20 | 2002-12-19 | Cormier Michel J.N. | Microprojection array immunization patch and method |
BR0209046A (pt) * | 2001-04-20 | 2004-11-09 | Alza Corp | Disposição de microprojeção que possui um agente benéfico contendo revestimento |
WO2003048031A2 (en) * | 2001-11-30 | 2003-06-12 | Alza Corporation | Methods and apparatuses for forming microprojection arrays |
HUP0402605A2 (hu) * | 2001-12-20 | 2005-06-28 | Alza Corporation | Eszköz mikroszkopikus bemetszések ejtésére állat bőrszövetén |
US6908453B2 (en) * | 2002-01-15 | 2005-06-21 | 3M Innovative Properties Company | Microneedle devices and methods of manufacture |
GB0210397D0 (en) | 2002-05-07 | 2002-06-12 | Ferring Bv | Pharmaceutical formulations |
AR040819A1 (es) * | 2002-08-08 | 2005-04-20 | Alza Corp | Dispositivo de administracion transdermica de vacuna que tiene microproyecciones revestidas |
AU2003275301A1 (en) * | 2002-09-30 | 2004-04-23 | Alza Corporation | Drug delivery device having coated microprojections incorporating vasoconstrictors |
AR042815A1 (es) * | 2002-12-26 | 2005-07-06 | Alza Corp | Dispositivo de suministro de agente activo que tiene miembros compuestos |
US20050123507A1 (en) * | 2003-06-30 | 2005-06-09 | Mahmoud Ameri | Formulations for coated microprojections having controlled solubility |
EP1638468B1 (en) * | 2003-06-30 | 2007-08-15 | Alza Corporation | Method for coating skin piercing microprojections |
CA2530531A1 (en) | 2003-06-30 | 2005-01-20 | Alza Corporation | Formulations for coated microprojections containing non-volatile counterions |
TW200513280A (en) * | 2003-07-02 | 2005-04-16 | Alza Corp | Microprojection array immunization patch and method |
MXPA06001409A (es) * | 2003-08-04 | 2006-08-25 | Johnson & Johnson | Metodo y dispositivo para mejorar flujo de agente trasdermico. |
AU2004268616B2 (en) | 2003-08-25 | 2010-10-07 | 3M Innovative Properties Company | Delivery of immune response modifier compounds |
CA2536443A1 (en) * | 2003-08-26 | 2005-03-03 | Alza Corporation | Device and method for intradermal cell implantation |
JP2007519613A (ja) * | 2003-10-23 | 2007-07-19 | アルザ・コーポレーシヨン | 微小突出部をコーティングするための安定化されたdnaの組成物 |
CA2543084A1 (en) * | 2003-10-24 | 2005-05-12 | Alza Corporation | Apparatus and method for enhancing transdermal drug delivery |
AU2004285484A1 (en) * | 2003-10-24 | 2005-05-12 | Alza Corporation | Pretreatment method and system for enhancing transdermal drug delivery |
BRPI0415986A (pt) * | 2003-10-28 | 2007-01-23 | Alza Corp | método e aparelho para reduzir a incidência do uso de tabaco |
EP1680154B1 (en) * | 2003-10-31 | 2012-01-04 | ALZA Corporation | Self-actuating applicator for microprojection array |
AU2004292954A1 (en) * | 2003-11-13 | 2005-06-09 | Alza Corporation | Composition and apparatus for transdermal delivery |
DE10353629A1 (de) * | 2003-11-17 | 2005-06-16 | Lts Lohmann Therapie-Systeme Ag | Vorrichtung zur transdermalen Verabreichung von Wirkstoffen |
WO2005051476A1 (en) * | 2003-11-28 | 2005-06-09 | Acrux Dds Pty Ltd | Method and system for rapid transdermal administration |
GB0402131D0 (en) | 2004-01-30 | 2004-03-03 | Isis Innovation | Delivery method |
US7914813B2 (en) | 2004-02-03 | 2011-03-29 | Hisamitsu Pharmaceutical Co., Inc. | Interface for transdermal drug administration device |
WO2007021762A2 (en) | 2005-08-09 | 2007-02-22 | The University Of North Carolina At Chapel Hill | Methods and materials for fabricating microfluidic devices |
BRPI0509493A (pt) | 2004-04-01 | 2007-09-11 | Alza Corp | aparelho e método para a liberação transdérmica de vacina da influenza |
AU2005235990A1 (en) * | 2004-04-13 | 2005-11-03 | Alza Corporation | Apparatus and method for transdermal delivery of multiple vaccines |
AU2005244734A1 (en) * | 2004-05-13 | 2005-12-01 | Alza Corporation | Apparatus and method for transdermal delivery of parathyroid hormone agents |
CA2566759A1 (en) * | 2004-05-19 | 2005-11-24 | Alza Corporation | Method and formulation for transdermal delivery of immunologically active agents |
US20060030811A1 (en) * | 2004-08-03 | 2006-02-09 | Wong Patrick S | Method and device for enhancing transdermal agent flux |
US20060100584A1 (en) * | 2004-08-10 | 2006-05-11 | Orest Olejnik | Needleless microprotrusion elastoplast system |
AR050608A1 (es) * | 2004-08-19 | 2006-11-08 | Alza Corp | Aparato y metodo para administracion transdermica de factores de crecimiento endotelial vascular |
KR20070099540A (ko) * | 2004-09-08 | 2007-10-09 | 알자 코포레이션 | 향상된 피부 점착성 및 순응도를 갖는 미세돌출부 어레이 |
WO2006047198A2 (en) * | 2004-10-26 | 2006-05-04 | Caritas St. Elizabeth Medical Center Of Boston, Inc. | Composition and method for using a cytokine to treat restenosis |
US20060093658A1 (en) * | 2004-10-26 | 2006-05-04 | Gayatri Sathyan | Apparatus and method for transdermal delivery of desmopressin |
US8057842B2 (en) * | 2004-11-18 | 2011-11-15 | 3M Innovative Properties Company | Method of contact coating a microneedle array |
JP4927751B2 (ja) * | 2004-11-18 | 2012-05-09 | スリーエム イノベイティブ プロパティズ カンパニー | マイクロニードルアレイのコーティング方法 |
EP2388078B1 (en) * | 2004-11-18 | 2013-03-20 | 3M Innovative Properties Co. | Method of contact coating a microneedle array |
AU2005306422A1 (en) | 2004-11-18 | 2006-05-26 | 3M Innovative Properties Company | Low-profile microneedle array applicator |
JP5882556B2 (ja) * | 2004-12-28 | 2016-03-09 | ナブテスコ株式会社 | 皮膚用針、皮膚用針製造装置および皮膚用針製造方法 |
WO2006079019A2 (en) * | 2005-01-21 | 2006-07-27 | Alza Corporation | Therapeutic peptide formulations for coating microneedles with improved stabitity containing at least one counterion |
TW200738252A (en) * | 2005-02-16 | 2007-10-16 | Alza Corp | Apparatus and method for transdermal delivery of Epoetin-based agents |
JP2008529750A (ja) * | 2005-02-16 | 2008-08-07 | アルザ コーポレイション | 生体適合性が改善されたマイクロプロジェクションアレイ |
EP1898807A1 (en) * | 2005-03-28 | 2008-03-19 | Alza Corporation | Microprojections with capillary control features and method |
US20060253079A1 (en) * | 2005-04-25 | 2006-11-09 | Mcdonough Justin | Stratum corneum piercing device |
US20070270738A1 (en) * | 2005-04-25 | 2007-11-22 | Wu Jeffrey M | Method of treating ACNE with stratum corneum piercing patch |
US20080009802A1 (en) * | 2005-04-25 | 2008-01-10 | Danilo Lambino | Method of treating acne with stratum corneum piercing device |
EP1888126A1 (en) * | 2005-06-02 | 2008-02-20 | Alza Corporation | Method for terminal sterilization of transdermal delivery devices |
WO2006130869A1 (en) * | 2005-06-02 | 2006-12-07 | Alza Corporation | Method for terminal sterilization of transdermal delivery devices |
US20080195035A1 (en) | 2005-06-24 | 2008-08-14 | Frederickson Franklyn L | Collapsible Patch and Method of Application |
US20070078414A1 (en) * | 2005-08-05 | 2007-04-05 | Mcallister Devin V | Methods and devices for delivering agents across biological barriers |
WO2007028167A2 (en) * | 2005-09-02 | 2007-03-08 | Iomai Corporation | Devices for transcutaneous delivery of vaccines and transdermal delivery of drugs and uses thereof |
CN101267896A (zh) * | 2005-09-12 | 2008-09-17 | 阿尔扎公司 | 可涂覆的透皮给药微突起组合件 |
CA2629193C (en) * | 2005-11-18 | 2016-03-29 | 3M Innovative Properties Company | Coatable compositions, coatings derived therefrom and microarrays having such coatings |
US8554317B2 (en) * | 2005-11-30 | 2013-10-08 | 3M Innovative Properties Company | Microneedle arrays and methods of use thereof |
WO2007075614A1 (en) * | 2005-12-21 | 2007-07-05 | 3M Innovative Properties Company | Microneedle devices |
US8632801B2 (en) * | 2005-12-28 | 2014-01-21 | Alza Corporation | Stable therapeutic formulations |
US8944804B2 (en) | 2006-01-04 | 2015-02-03 | Liquidia Technologies, Inc. | Nanostructured surfaces for biomedical/biomaterial applications and processes thereof |
WO2007106597A2 (en) * | 2006-03-15 | 2007-09-20 | Alza Corporation | Method for the transdermal delivery of parathyroid hormone agents for treating osteopenia |
US20070224252A1 (en) * | 2006-03-27 | 2007-09-27 | Trautman Joseph C | Microprojections with capillary control features and method |
US9119945B2 (en) * | 2006-04-20 | 2015-09-01 | 3M Innovative Properties Company | Device for applying a microneedle array |
US20070299388A1 (en) * | 2006-04-25 | 2007-12-27 | Alza Corporation | Microprojection array application with multilayered microprojection member for high drug loading |
US20070293816A1 (en) * | 2006-04-25 | 2007-12-20 | Alza Corporation | Microprojection Array Application with Grouped Microprojections for High Drug Loading |
JP4821993B2 (ja) * | 2006-07-21 | 2011-11-24 | 芳一 飛永 | マイクロインプリメント及びその製造方法 |
AU2008241470B2 (en) | 2007-04-16 | 2013-11-07 | Corium Pharma Solutions, Inc. | Solvent-cast microneedle arrays containing active |
WO2008139648A1 (ja) | 2007-05-15 | 2008-11-20 | Hisamitsu Pharmaceutical Co., Inc. | マイクロニードルのコーティング方法 |
US20100137429A1 (en) * | 2007-06-21 | 2010-06-03 | Fujimoto Co., Ltd. | Composition for transdermal or transmucosal administration |
BRPI0814986A2 (pt) | 2007-08-06 | 2015-02-03 | Serenity Pharmaceuticals Corp | Métodos e dispositivos para a distribuição de fármaco desmopresina. |
WO2009040548A1 (en) * | 2007-09-28 | 2009-04-02 | The Queen's University Of Belfast | Delivery device and method |
US7806878B2 (en) * | 2007-10-17 | 2010-10-05 | Cascio Gregory R | Medicament applicator |
US20090105673A1 (en) * | 2007-10-17 | 2009-04-23 | Cascio Gregory R | Medicament applicator |
AU2008327083B2 (en) * | 2007-11-21 | 2014-01-16 | Bioserentach Co., Ltd. | Preparation for application to body surface and preparation holding sheet for application to body surface |
EP2231257A4 (en) * | 2007-12-24 | 2013-11-06 | Univ Queensland | APPLICATION METHOD |
WO2009097660A1 (en) | 2008-02-07 | 2009-08-13 | The University Of Queensland | Patch production |
US20100286045A1 (en) | 2008-05-21 | 2010-11-11 | Bjarke Mirner Klein | Methods comprising desmopressin |
US11963995B2 (en) | 2008-05-21 | 2024-04-23 | Ferring B.V. | Methods comprising desmopressin |
PT2296686E (pt) | 2008-05-21 | 2014-05-23 | Ferring Bv | Desmopressina orodispersível para aumentar o período inicial de sono não perturbado por noctúria |
AU2009250341A1 (en) * | 2008-05-23 | 2009-11-26 | The University Of Queensland | Analyte detection using a needle projection patch |
US8834446B2 (en) * | 2008-06-12 | 2014-09-16 | DePuy Synthes Products, LLC | Pulsatile flux drug delivery |
AU2009329806A1 (en) | 2008-12-22 | 2010-07-01 | The University Of Queensland | Patch production |
JP5820805B2 (ja) * | 2009-04-24 | 2015-11-24 | コリウム インターナショナル, インコーポレイテッド | マイクロプロジェクションのアレイの製造のためのプロセス |
US20100286600A1 (en) * | 2009-05-08 | 2010-11-11 | Bommannan D Bommi | Transdermal patch device |
DE102009056746A1 (de) | 2009-12-04 | 2011-06-09 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System für die Verabreichung von Peptiden |
DE102009056745A1 (de) | 2009-12-04 | 2011-06-09 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System für die Verabreichung von Peptiden |
US20110144591A1 (en) * | 2009-12-11 | 2011-06-16 | Ross Russell F | Transdermal Delivery Device |
JPWO2011105496A1 (ja) * | 2010-02-24 | 2013-06-20 | 久光製薬株式会社 | マイクロニードルデバイス |
RU2569029C2 (ru) * | 2010-05-04 | 2015-11-20 | Кориум Интернэшнл, Инк. | Аппликаторы для микроигл |
AU2011248108B2 (en) | 2010-05-04 | 2016-05-26 | Corium Pharma Solutions, Inc. | Method and device for transdermal delivery of parathyroid hormone using a microprojection array |
CA2799183A1 (en) | 2010-05-12 | 2011-11-17 | Radius Health, Inc. | Therapeutic regimens |
CA2800253C (en) | 2010-05-28 | 2022-07-12 | 3M Innovative Properties Company | Aqueous formulations for coating microneedle arrays |
US9943673B2 (en) | 2010-07-14 | 2018-04-17 | Vaxxas Pty Limited | Patch applying apparatus |
AU2011312490B2 (en) | 2010-09-28 | 2015-06-25 | Radius Pharmaceuticals, Inc. | Selective androgen receptor modulators |
KR102014203B1 (ko) | 2011-02-18 | 2019-08-26 | 아사나 바이오사이언시스 엘엘씨 | 아미노인단 화합물 및 통증 치료에서 그것의 용도 |
US8512679B2 (en) | 2011-03-04 | 2013-08-20 | Elwha Llc | Glassy compositions |
US8301238B2 (en) * | 2011-03-31 | 2012-10-30 | Incline Therapeutics, Inc. | Two-part electrotransport device |
JP5870551B2 (ja) * | 2011-08-26 | 2016-03-01 | 大日本印刷株式会社 | マイクロニードルデバイスの製造方法 |
JP2013043034A (ja) * | 2011-08-26 | 2013-03-04 | Dainippon Printing Co Ltd | マイクロニードルデバイスの製造方法 |
EP3881781B1 (en) | 2011-10-12 | 2023-03-29 | Vaxxas Pty Limited | Delivery device |
US8685418B2 (en) | 2011-10-24 | 2014-04-01 | Endo Pharmaceuticals Inc. | Cyclohexylamines |
KR101392947B1 (ko) | 2011-12-13 | 2014-05-12 | 주식회사 스몰랩 | 섬유를 포함하는 미세돌기 마사지 패치 및 그 제조 방법 |
US20130296824A1 (en) * | 2012-05-03 | 2013-11-07 | Uc Biodevices Corporation | Microneedle based transdermal drug delivery device and method |
JP6833317B2 (ja) * | 2012-06-15 | 2021-02-24 | ユニバーシティ オブ ワシントン スルー イッツ センター フォー コマーシャリゼーション | 微細構造に基づく創傷閉鎖デバイス |
KR102265808B1 (ko) | 2012-12-21 | 2021-06-16 | 코리움, 인크. | 치료제의 전달을 위한 마이크로어레이 및 그것의 사용방법 |
JP6487899B2 (ja) | 2013-03-12 | 2019-03-20 | コリウム インターナショナル, インコーポレイテッド | 微小突起アプリケータ |
MX2015012933A (es) | 2013-03-15 | 2016-09-19 | Corium Int Inc | Micrordenamiento para suministro de agente terapeutico y metodos de uso. |
JP2016514133A (ja) | 2013-03-15 | 2016-05-19 | コリウム インターナショナル, インコーポレイテッド | ポリマーを含まない微細構造物を含むマイクロアレイ、製造方法および使用方法 |
US20150038897A1 (en) | 2013-07-30 | 2015-02-05 | Zosano Pharma, Inc. | Low-Profile Microneedle Patch Applicator |
WO2015027173A1 (en) | 2013-08-22 | 2015-02-26 | Zp Opco, Inc. | Stable glucagon peptide formulations |
US9782344B2 (en) | 2013-08-22 | 2017-10-10 | Zp Opco, Inc. | Stable glucagon peptide formulations |
KR20220112867A (ko) | 2013-12-16 | 2022-08-11 | 에이비에스 디벨롭먼트 원 인코포레이티드 | P2x3 및/또는 p2x2/3 화합물 및 방법 |
EP3137153A4 (en) * | 2014-04-30 | 2017-11-29 | Kimberly-Clark Worldwide, Inc. | Transdermal drug delivery apparatus and methods |
GB201410270D0 (en) | 2014-06-10 | 2014-07-23 | Univ Belfast | Cell delivery system and method |
EP3188714A1 (en) | 2014-09-04 | 2017-07-12 | Corium International, Inc. | Microstructure array, methods of making, and methods of use |
JP6906885B2 (ja) | 2014-11-14 | 2021-07-21 | ロレアル | しわを減少させるためのマイクロニードルシート |
US9925233B2 (en) | 2015-01-30 | 2018-03-27 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
US9687526B2 (en) | 2015-01-30 | 2017-06-27 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
US9375478B1 (en) | 2015-01-30 | 2016-06-28 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
US9937223B2 (en) | 2015-01-30 | 2018-04-10 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
US9744209B2 (en) | 2015-01-30 | 2017-08-29 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
US9750785B2 (en) | 2015-01-30 | 2017-09-05 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
EP3253440B1 (en) | 2015-02-02 | 2022-12-21 | Vaxxas Pty Limited | Microprojection array applicator |
IL255148B2 (en) | 2015-04-29 | 2023-04-01 | Radius Pharmaceuticals Inc | 1901 rad for use in a method to inhibit a cancerous growth or induce tumor regression in a patient who is resistant to the drug and/or has cancer positive for an estrogen receptor alpha mutation |
EP3310425B1 (en) * | 2015-05-22 | 2021-01-20 | L'Oréal | Applicators for treating skin conditions |
US10857093B2 (en) | 2015-06-29 | 2020-12-08 | Corium, Inc. | Microarray for delivery of therapeutic agent, methods of use, and methods of making |
WO2017045031A1 (en) | 2015-09-18 | 2017-03-23 | Vaxxas Pty Limited | Microprojection arrays with microprojections having large surface area profiles |
US20180264244A1 (en) | 2015-09-28 | 2018-09-20 | Vaxxas Pty Limited | Microprojection arrays with enhanced skin penetrating properties and methods thereof |
WO2017079611A1 (en) | 2015-11-02 | 2017-05-11 | Zp Opco, Inc. | Stable glucagon peptide formulations |
US9918932B2 (en) | 2016-02-19 | 2018-03-20 | Zosano Pharma Corporation | Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines |
US10568937B2 (en) | 2016-04-18 | 2020-02-25 | Radius Health, Inc. | Formulations of abaloparatide, transdermal patches thereof, and uses thereof |
KR102397890B1 (ko) | 2016-06-22 | 2022-05-12 | 일립시스 파마 리미티드 | Ar+ 유방암 치료 방법 |
RU2019112740A (ru) | 2016-09-30 | 2020-11-02 | АСАНА БАЙОСАЙЕНСИЗ, ЭлЭлСи | P2x3 и/или p2x2/3 соединения и способы |
JP7116430B2 (ja) * | 2016-12-12 | 2022-08-10 | 株式会社 メドレックス | マイクロニードル貼付剤 |
KR102322802B1 (ko) | 2017-01-05 | 2021-11-04 | 래디어스 파마슈티컬스, 인코포레이티드 | Rad1901-2hcl의 다형 형태 |
CN115923337A (zh) | 2017-03-31 | 2023-04-07 | 瓦克萨斯私人有限公司 | 用于涂覆表面的设备和方法 |
CA3065371A1 (en) | 2017-06-13 | 2018-12-20 | Vaxxas Pty Limited | Quality control of substrate coatings |
EP3661587A4 (en) | 2017-08-04 | 2021-06-09 | Vaxxas Pty Limited | COMPACT HIGH MECHANICAL ENERGY STORAGE AND LOW RELEASE FORCE ACTUATOR FOR MICROPROJECTION NETWORK (PRM) PATCH DELIVERY |
EP3672570A1 (en) | 2017-08-23 | 2020-07-01 | Zosano Pharma Corporation | Method of rapidly achieving therapeutic concentrations of zolmitriptan for treatment of migraines and cluster headaches |
US11660264B2 (en) | 2017-08-23 | 2023-05-30 | Emergex USA Corporation | Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches |
US11660265B2 (en) | 2018-06-28 | 2023-05-30 | Emergex USA Corporation | Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches |
IL279853B1 (en) | 2018-07-04 | 2024-09-01 | Radius Pharmaceuticals Inc | Polymorphic forms of RAD 1901-2HCL |
Family Cites Families (77)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US25637A (en) * | 1859-10-04 | Cooking-stove | ||
USRE25637E (en) | 1964-09-08 | Means for vaccinating | ||
US3123212A (en) * | 1964-03-03 | Multiple disposable intracutaneous injector package | ||
US2619962A (en) * | 1948-02-19 | 1952-12-02 | Res Foundation | Vaccination appliance |
US2893392A (en) * | 1958-01-08 | 1959-07-07 | American Cyanamid Co | Article of manufacture for intracutaneous injections |
US3072122A (en) * | 1959-01-15 | 1963-01-08 | Rosenthal Sol Roy | Package for transcutaneous injection |
US3136314A (en) * | 1960-08-01 | 1964-06-09 | Kravitz Harvey | Vaccinating devices |
US3221739A (en) * | 1962-03-26 | 1965-12-07 | Rosenthal Sol Roy | Injection device |
US3221740A (en) * | 1962-08-31 | 1965-12-07 | Rosenthal Sol Roy | Injection device |
US3470011A (en) * | 1967-02-07 | 1969-09-30 | American Cyanamid Co | Process for applying liquid biologicals to applicators for intracutaneous injection |
US3964482A (en) * | 1971-05-17 | 1976-06-22 | Alza Corporation | Drug delivery device |
US3678150A (en) * | 1971-07-27 | 1972-07-18 | American Cyanamid Co | Process for improving the stability of ppd, qt and histoplasmin on tine applicators |
CH580961A5 (en) * | 1972-01-13 | 1976-10-29 | Alza Corp | Dispenser - functioning by osmotic pressure using active agents in solid or semi solid form |
BE795384A (fr) | 1972-02-14 | 1973-08-13 | Ici Ltd | Pansements |
OA05448A (fr) * | 1975-10-16 | 1981-03-31 | Manufrance Manufacture Francai | Dispositif vaccinateur multipénétrant. |
FR2474856A1 (fr) * | 1980-01-31 | 1981-08-07 | Merieux Inst | Dispositif scarificateur |
SE8501990D0 (sv) * | 1985-04-24 | 1985-04-24 | Pharmacia Ab | Beleggningsforfarande |
US4878892A (en) * | 1987-02-10 | 1989-11-07 | Drug Delivery Systems Inc. | Electrolytic transdermal delivery of polypeptides |
CA2016900A1 (en) | 1989-07-06 | 1991-01-06 | Ronald J. Filipski | Tines structure in clinical applicator |
EP0429842B1 (en) | 1989-10-27 | 1996-08-28 | Korea Research Institute Of Chemical Technology | Device for the transdermal administration of protein or peptide drug |
US5279544A (en) | 1990-12-13 | 1994-01-18 | Sil Medics Ltd. | Transdermal or interdermal drug delivery devices |
US5321008A (en) * | 1991-01-10 | 1994-06-14 | Amylin Pharmaceuticals, Inc. | Methods and compositions for treatment of diabetes mellitus, hypoglycemia, and other conditions |
US5298256A (en) * | 1992-04-28 | 1994-03-29 | Corint, Ltd. | Desmopressin buccal patch composition |
US5457041A (en) * | 1994-03-25 | 1995-10-10 | Science Applications International Corporation | Needle array and method of introducing biological substances into living cells using the needle array |
US5487726A (en) * | 1994-06-16 | 1996-01-30 | Ryder International Corporation | Vaccine applicator system |
MX9701394A (es) | 1994-08-04 | 1998-03-31 | Quadrant Holdings Cambridge | Sistemas de administracion de solidos para la liberacion controlada de moleculas incorporadas en losmismos y metodos para hacer los mismos. |
WO1996010630A1 (en) | 1994-09-30 | 1996-04-11 | Rutgers, The State University | Direct introduction of foreign materials into cells |
AU4256496A (en) | 1994-12-09 | 1996-06-26 | Novartis Ag | Transdermal system |
US5985316A (en) * | 1995-04-28 | 1999-11-16 | Alza Corporation | Composition and method of enhancing electrotransport agent delivery |
WO1996037155A1 (en) | 1995-05-22 | 1996-11-28 | Silicon Microdevices, Inc. | Micromechanical device and method for enhancing delivery of compounds through the skin |
AU5869796A (en) | 1995-05-22 | 1996-12-11 | Ned A. Godshall | Micromechanical patch for enhancing the delivery of compound s through the skin |
DE19525607A1 (de) | 1995-07-14 | 1997-01-16 | Boehringer Ingelheim Kg | Transcorneales Arzneimittelfreigabesystem |
US6143037A (en) | 1996-06-12 | 2000-11-07 | The Regents Of The University Of Michigan | Compositions and methods for coating medical devices |
ES2195151T3 (es) | 1996-06-18 | 2003-12-01 | Alza Corp | Dispositivo de mejora de aporte o de muestreo de agentes transdermicos. |
CA2259437C (en) | 1996-07-03 | 2006-12-05 | Altea Technologies, Inc. | Multiple mechanical microporation of skin or mucosa |
US5738728A (en) * | 1996-07-26 | 1998-04-14 | Bio Dot, Inc. | Precision metered aerosol dispensing apparatus |
US5743960A (en) | 1996-07-26 | 1998-04-28 | Bio-Dot, Inc. | Precision metered solenoid valve dispenser |
US5741554A (en) | 1996-07-26 | 1998-04-21 | Bio Dot, Inc. | Method of dispensing a liquid reagent |
US5916524A (en) * | 1997-07-23 | 1999-06-29 | Bio-Dot, Inc. | Dispensing apparatus having improved dynamic range |
JP4054381B2 (ja) | 1996-09-17 | 2008-02-27 | デカ・プロダクツ・リミテッド・パートナーシップ | 移送による薬伝達システム |
GB9623634D0 (en) | 1996-11-13 | 1997-01-08 | Bpsi Holdings Inc | Method and apparatus for the coating of substrates for pharmaceutical use |
KR100453132B1 (ko) | 1996-12-20 | 2004-10-15 | 앨자 코포레이션 | 경피 약제 플럭스를 향상시키기 위한 장치 및 방법 |
DE19654391A1 (de) | 1996-12-27 | 1998-07-02 | Basf Ag | Katalysator zur selektiven Herstellung von Propylen aus Propan |
BR9714113A (pt) | 1996-12-31 | 2000-03-21 | Shell Int Research | Plataforma de tirante |
US6918901B1 (en) | 1997-12-10 | 2005-07-19 | Felix Theeuwes | Device and method for enhancing transdermal agent flux |
KR100557261B1 (ko) | 1997-12-11 | 2006-03-07 | 알자 코포레이션 | 경피성 작용제 유동률을 증진시키기 위한 장치 |
ATE302041T1 (de) * | 1997-12-11 | 2005-09-15 | Alza Corp | Vorrichtung zur erhöhung des transdermalen wirkstoffeflusses |
DE69806963T2 (de) | 1997-12-11 | 2002-11-21 | Alza Corp., Mountain View | Vorrichtung zur erhöhung des transdermalen wirkstoffeflusses |
US6091975A (en) | 1998-04-01 | 2000-07-18 | Alza Corporation | Minimally invasive detecting device |
JP2002517300A (ja) | 1998-06-10 | 2002-06-18 | ジョージア テック リサーチ コーポレイション | 微小針デバイスおよび製造方法ならびにそれらの使用 |
CN1315877A (zh) | 1998-08-31 | 2001-10-03 | 强生消费者公司 | 含刀片的电传送装置 |
EP1140275A1 (en) | 1998-12-18 | 2001-10-10 | Minimed Inc. | Insertion sets with micro-piercing members for use with medical devices and methods of using the same |
JP4072268B2 (ja) | 1998-12-24 | 2008-04-09 | キヤノン株式会社 | 皮膚吸収型薬液投与装置 |
ATE256484T1 (de) | 1999-01-28 | 2004-01-15 | Cyto Pulse Sciences Inc | Einbringen von makromolekülen in zellen |
US6537242B1 (en) * | 2000-06-06 | 2003-03-25 | Becton, Dickinson And Company | Method and apparatus for enhancing penetration of a member for the intradermal sampling or administration of a substance |
US6589202B1 (en) * | 2000-06-29 | 2003-07-08 | Becton Dickinson And Company | Method and apparatus for transdermally sampling or administering a substance to a patient |
GB0017999D0 (en) | 2000-07-21 | 2000-09-13 | Smithkline Beecham Biolog | Novel device |
CN100421653C (zh) * | 2000-09-08 | 2008-10-01 | 阿尔扎公司 | 通过抑制通道关闭来抑制药物透皮通量减少的方法 |
JP4659332B2 (ja) * | 2000-10-13 | 2011-03-30 | アルザ・コーポレーシヨン | 微小突起を用いて皮膚を穿孔するための装置および方法 |
US7419481B2 (en) * | 2000-10-13 | 2008-09-02 | Alza Corporation | Apparatus and method for piercing skin with microprotrusions |
RU2278623C2 (ru) * | 2000-10-13 | 2006-06-27 | Алза Корпорейшн | Держатель микровыступающего элемента для силового аппликатора |
MXPA03003301A (es) * | 2000-10-13 | 2004-12-13 | Johnson & Johnson | Aplicador de un conjunto de microsalientes mediante impacto. |
US6855372B2 (en) | 2001-03-16 | 2005-02-15 | Alza Corporation | Method and apparatus for coating skin piercing microprojections |
BR0209046A (pt) * | 2001-04-20 | 2004-11-09 | Alza Corp | Disposição de microprojeção que possui um agente benéfico contendo revestimento |
WO2003048031A2 (en) * | 2001-11-30 | 2003-06-12 | Alza Corporation | Methods and apparatuses for forming microprojection arrays |
HUP0402605A2 (hu) * | 2001-12-20 | 2005-06-28 | Alza Corporation | Eszköz mikroszkopikus bemetszések ejtésére állat bőrszövetén |
US7015262B2 (en) | 2002-05-01 | 2006-03-21 | Lifescan, Inc. | Hydrophilic coatings for medical implements |
KR20050054483A (ko) | 2002-06-28 | 2005-06-10 | 알자 코포레이션 | 코팅된 미세돌출부를 갖는 경피용 약물 전달 장치 |
AR042815A1 (es) * | 2002-12-26 | 2005-07-06 | Alza Corp | Dispositivo de suministro de agente activo que tiene miembros compuestos |
US20050123507A1 (en) * | 2003-06-30 | 2005-06-09 | Mahmoud Ameri | Formulations for coated microprojections having controlled solubility |
CA2530531A1 (en) * | 2003-06-30 | 2005-01-20 | Alza Corporation | Formulations for coated microprojections containing non-volatile counterions |
CA2543280A1 (en) * | 2003-10-28 | 2005-05-19 | Alza Corporation | Delivery of polymer conjugates of therapeutic peptides and proteins via coated microporjections |
EP1680154B1 (en) * | 2003-10-31 | 2012-01-04 | ALZA Corporation | Self-actuating applicator for microprojection array |
AU2004292954A1 (en) * | 2003-11-13 | 2005-06-09 | Alza Corporation | Composition and apparatus for transdermal delivery |
AU2005244734A1 (en) * | 2004-05-13 | 2005-12-01 | Alza Corporation | Apparatus and method for transdermal delivery of parathyroid hormone agents |
WO2006079019A2 (en) * | 2005-01-21 | 2006-07-27 | Alza Corporation | Therapeutic peptide formulations for coating microneedles with improved stabitity containing at least one counterion |
JP5277456B2 (ja) * | 2005-01-31 | 2013-08-28 | アルザ コーポレイション | 低い変動性を有するコーティングマイクロプロジェクション、及びその生成法 |
-
2001
- 2001-10-26 JP JP2002591082A patent/JP4659336B2/ja not_active Expired - Fee Related
- 2001-10-26 DK DK01273947T patent/DK1333880T3/da active
- 2001-10-26 RU RU2003112256/14A patent/RU2282468C2/ru not_active IP Right Cessation
- 2001-10-26 EP EP01273947A patent/EP1333880B1/en not_active Expired - Lifetime
- 2001-10-26 MX MXPA03003815A patent/MXPA03003815A/es active IP Right Grant
- 2001-10-26 EP EP09005205A patent/EP2085109A3/en not_active Withdrawn
- 2001-10-26 CN CNB018213596A patent/CN1239212C/zh not_active Expired - Fee Related
- 2001-10-26 IL IL15558301A patent/IL155583A0/xx unknown
- 2001-10-26 PL PL01365677A patent/PL365677A1/xx unknown
- 2001-10-26 HU HU0302924A patent/HUP0302924A2/hu unknown
- 2001-10-26 CZ CZ20031164A patent/CZ20031164A3/cs unknown
- 2001-10-26 US US10/045,842 patent/US7537795B2/en not_active Expired - Lifetime
- 2001-10-26 DE DE60138407T patent/DE60138407D1/de not_active Expired - Lifetime
- 2001-10-26 AU AU2001297823A patent/AU2001297823B2/en not_active Ceased
- 2001-10-26 AT AT01273947T patent/ATE428466T1/de not_active IP Right Cessation
- 2001-10-26 PT PT01273947T patent/PT1333880E/pt unknown
- 2001-10-26 WO PCT/US2001/051496 patent/WO2002094368A1/en active IP Right Grant
- 2001-10-26 BR BR0114909-1A patent/BR0114909A/pt not_active Application Discontinuation
- 2001-10-26 NZ NZ525551A patent/NZ525551A/en unknown
- 2001-10-26 KR KR1020037005755A patent/KR100812097B1/ko active IP Right Grant
- 2001-10-26 CA CA002427381A patent/CA2427381A1/en not_active Abandoned
- 2001-10-26 ES ES01273947T patent/ES2322023T3/es not_active Expired - Lifetime
-
2003
- 2003-04-25 NO NO20031875A patent/NO20031875L/no not_active Application Discontinuation
- 2003-05-22 ZA ZA200303988A patent/ZA200303988B/en unknown
- 2003-05-23 MA MA27175A patent/MA26061A1/fr unknown
-
2006
- 2006-02-02 US US11/347,779 patent/US8663155B2/en not_active Expired - Lifetime
- 2006-11-01 JP JP2006298066A patent/JP4875457B2/ja not_active Expired - Fee Related
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK1333880T3 (da) | Indretninger med coatede mikrofremspring til medikamentafgivelse gennem huden | |
BR0110243A (pt) | Sistema de aplicação de droga de liberação prolongada, e, métodos para o tratamento de um organismo de mamìfero, para fornecer administração controlada e prolongada de um agente eficaz para se obter um efeito fisiológico ou farmacológico local ou sistêmico desejado, e de fabricação de um sistema de aplicação prolongada de droga | |
BRPI0517501A (pt) | dispositivo médico apropriado para uso na administração de um componente ativo na ou através da pele | |
WO2004030743A3 (en) | Drug delivery device having coated microprojections incorporating vasoconstrictors | |
NO20034684D0 (no) | Innretning for administrering av midler gjennom stratum corcum | |
EA200301200A1 (ru) | Проникающая через кожу композиция селективного ингибитора циклооксигеназы-2 | |
FR2830767B1 (fr) | Dispositif de delivrance de medicaments par iontophorese ou electroporation introculaire | |
BR0016402A (pt) | Método para aumentar a permeabilidade da pele ou do tecido mucoso a agentes farmaceuticamente ou cosmeticamente ativos administrados por via tópica ou transdérmica | |
HK1071847A1 (en) | Dosage forms having prolonged active ingredient release | |
AR039130A2 (es) | Metodo de administracion de un agente farmaceuticamente activo a un ojo humano | |
CA2511995A1 (en) | Pharmaceutical preparations for treatments of diseases and disorders of the breast | |
WO2004105729A3 (en) | Transdermal vaccine delivery device having coated microprotrusions | |
NO20043871L (no) | Legemiddelformuleringer med kontrollert frigjoring som inneholder et baererpeptid | |
ATE388687T1 (de) | Medikamentöse verabreichung von nikotin in form von kaugummi | |
DK324687A (da) | Transdermalt farmeceutisk praeparat | |
WO2001013898A3 (en) | Pharmaceutical formulations with different release times | |
DE60008425D1 (de) | Medikamentenabgabevorrichtung mit einer feuchtigkeitsbeständigen beschichtung | |
WO2006016351A3 (en) | Drug delivery in the coronary sinus | |
WO2003030793A1 (en) | Hydrating nasal gel and applicator | |
ES2188513T3 (es) | Utilizacion de desoxipeganina para el tratamiento de la drogodependencia. | |
US4873266A (en) | Menthone enhancement of transdermal drug delivery | |
JP3425469B2 (ja) | ジェットインジェクション経皮吸収装置 | |
AR062894A1 (es) | Formulaciones para administracion terapeutica de hormona de estimulacion del tiroides (ths) | |
MX9306791A (es) | Suministro transdermico de cetorolac. | |
BR0312333A (pt) | Terapia de combinação e agente para sua execução |