WO2008139648A1 - マイクロニードルのコーティング方法 - Google Patents

マイクロニードルのコーティング方法 Download PDF

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Publication number
WO2008139648A1
WO2008139648A1 PCT/JP2007/070377 JP2007070377W WO2008139648A1 WO 2008139648 A1 WO2008139648 A1 WO 2008139648A1 JP 2007070377 W JP2007070377 W JP 2007070377W WO 2008139648 A1 WO2008139648 A1 WO 2008139648A1
Authority
WO
WIPO (PCT)
Prior art keywords
microneedles
apertures
coating
coating liquid
mask plate
Prior art date
Application number
PCT/JP2007/070377
Other languages
English (en)
French (fr)
Inventor
Seiji Tokumoto
Toshiyuki Matsudo
Tetuji Kuwahara
Original Assignee
Hisamitsu Pharmaceutical Co., Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hisamitsu Pharmaceutical Co., Inc. filed Critical Hisamitsu Pharmaceutical Co., Inc.
Priority to US12/599,394 priority Critical patent/US8771781B2/en
Priority to EP07830111.6A priority patent/EP2153863B1/en
Priority to JP2009513965A priority patent/JP5298011B2/ja
Publication of WO2008139648A1 publication Critical patent/WO2008139648A1/ja

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
    • B81C1/00—Manufacture or treatment of devices or systems in or on a substrate
    • B81C1/00015—Manufacture or treatment of devices or systems in or on a substrate for manufacturing microsystems
    • B81C1/00206—Processes for functionalising a surface, e.g. provide the surface with specific mechanical, chemical or biological properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053—Methods for producing microneedles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B2201/00—Specific applications of microelectromechanical systems
    • B81B2201/05—Microfluidics
    • B81B2201/055—Microneedles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B2203/00—Basic microelectromechanical structures
    • B81B2203/03—Static structures
    • B81B2203/0361—Tips, pillars

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Manufacturing & Machinery (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Materials For Medical Uses (AREA)

Abstract

　マイクロニードルデバイスのマイクロニードルを精度良く、簡便かつ量産可能にコーティングするためのマイクロニードルのコーティング方法を提供する。この方法は、複数のマイクロニードル（２１）を有するマイクロニードルデバイス（２２）をテーブル（２３）上に設置し、一方、複数の開口部（２４）を有するマスク版（２５）を枠体（２６）に固定し、コーティング液（２７）をマスク版（２５）上でヘラ（２８）により矢印Ａ方向に引いて、開口部（２４）にコーティング液を充填する。コーティング液（２７）の開口部（２４）への充填前または充填後に開口部（２４）にマイクロニードル（２１）が挿入され、これによりマイクロニードル（２１）をコーティングする。
PCT/JP2007/070377 2007-05-15 2007-10-18 マイクロニードルのコーティング方法 WO2008139648A1 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US12/599,394 US8771781B2 (en) 2007-05-15 2007-10-18 Method of coating microneedle
EP07830111.6A EP2153863B1 (en) 2007-05-15 2007-10-18 Method of coating microneedle
JP2009513965A JP5298011B2 (ja) 2007-05-15 2007-10-18 マイクロニードルのコーティング方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-129736 2007-05-15
JP2007129736 2007-05-15

Publications (1)

Publication Number Publication Date
WO2008139648A1 true WO2008139648A1 (ja) 2008-11-20

Family

ID=40001876

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2007/070377 WO2008139648A1 (ja) 2007-05-15 2007-10-18 マイクロニードルのコーティング方法

Country Status (4)

Country Link
US (1) US8771781B2 (ja)
EP (1) EP2153863B1 (ja)
JP (1) JP5298011B2 (ja)
WO (1) WO2008139648A1 (ja)

Cited By (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009008951A2 (en) * 2007-07-09 2009-01-15 Apogee Technology, Inc. Methods and systems for coating a microneedle with a dosage of a biologically active compound
WO2010074239A1 (ja) * 2008-12-26 2010-07-01 久光製薬株式会社 マイクロニードルデバイス
WO2010087300A1 (ja) * 2009-01-30 2010-08-05 久光製薬株式会社 マイクロニードルデバイス
WO2010143689A1 (ja) * 2009-06-10 2010-12-16 久光製薬株式会社 マイクロニードルデバイス
JP2011224308A (ja) * 2010-04-21 2011-11-10 Kosumedei Seiyaku Kk マイクロニードル溶着法
WO2012066506A2 (en) 2010-11-18 2012-05-24 University College Cork Method
JP2012158607A (ja) * 2012-05-02 2012-08-23 Kosumedei Seiyaku Kk マイクロニードル溶着法
WO2012128363A1 (ja) * 2011-03-24 2012-09-27 コスメディ製薬株式会社 Ｐｅｄｆマイクロニードルアレイ及びその製造方法
JP2012524637A (ja) * 2009-04-24 2012-10-18 コリウム インターナショナル， インコーポレイテッド マイクロプロジェクションのアレイの製造のためのプロセス
JP2013043034A (ja) * 2011-08-26 2013-03-04 Dainippon Printing Co Ltd マイクロニードルデバイスの製造方法
JP2013043035A (ja) * 2011-08-26 2013-03-04 Dainippon Printing Co Ltd マイクロニードルデバイスの製造方法
WO2013057819A1 (ja) * 2011-10-20 2013-04-25 コスメディ製薬株式会社 マイクロニードル溶着法
JP2013094662A (ja) * 2012-05-02 2013-05-20 Kosumedei Seiyaku Kk マイクロニードル溶着法
WO2013122160A1 (ja) 2012-02-17 2013-08-22 コスメディ製薬株式会社 短時間溶解型マイクロニードル
JP2013177376A (ja) * 2012-02-09 2013-09-09 Hisamitsu Pharmaceut Co Inc マイクロニードル用ゾルミトリプタン含有コーティング組成物及びマイクロニードルデバイス
US20140066843A1 (en) * 2011-03-07 2014-03-06 3M Innovative Properties Company Microneedle devices and methods
US20140066842A1 (en) * 2011-03-07 2014-03-06 3M Innovative Properties Company Microneedle devices and methods
US8696638B2 (en) 2009-07-23 2014-04-15 Hisamitsu Pharmaceutical Co., Inc. Microneedle array
US8771781B2 (en) 2007-05-15 2014-07-08 Hisamitsu Pharmaceutical Co., Inc. Method of coating microneedle
WO2014192890A1 (ja) 2013-05-29 2014-12-04 久光製薬株式会社 マイクロニードル製剤製造用システム及び空調方法
WO2015016235A1 (ja) * 2013-07-30 2015-02-05 Ａｓｔｉ株式会社 マイクロニードルアレイとマイクロニードルアレイ製造方法
US9114238B2 (en) 2007-04-16 2015-08-25 Corium International, Inc. Solvent-cast microprotrusion arrays containing active ingredient
US9498524B2 (en) 2007-04-16 2016-11-22 Corium International, Inc. Method of vaccine delivery via microneedle arrays
WO2017135290A1 (ja) * 2016-02-03 2017-08-10 コスメディ製薬株式会社 マイクロニードル用塗布液、マイクロニードル塗布物、及びマイクロニードルアレイ
US9962534B2 (en) 2013-03-15 2018-05-08 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
US10195409B2 (en) 2013-03-15 2019-02-05 Corium International, Inc. Multiple impact microprojection applicators and methods of use
US10245422B2 (en) 2013-03-12 2019-04-02 Corium International, Inc. Microprojection applicators and methods of use
WO2019088315A1 (ko) * 2017-11-01 2019-05-09 주식회사 엘지생활건강 탈모 방지제 및 발모 치료제 전달을 위한 용해성 미세바늘 패치
US10384046B2 (en) 2013-03-15 2019-08-20 Corium, Inc. Microarray for delivery of therapeutic agent and methods of use
US10384045B2 (en) 2013-03-15 2019-08-20 Corium, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
US10624843B2 (en) 2014-09-04 2020-04-21 Corium, Inc. Microstructure array, methods of making, and methods of use
US10857093B2 (en) 2015-06-29 2020-12-08 Corium, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
US10994111B2 (en) 2013-02-14 2021-05-04 Cosmed Pharmaceutical Co., Ltd. Drug-holding microneedle array and manufacturing method thereof
US11052231B2 (en) 2012-12-21 2021-07-06 Corium, Inc. Microarray for delivery of therapeutic agent and methods of use
US11419816B2 (en) 2010-05-04 2022-08-23 Corium, Inc. Method and device for transdermal delivery of parathyroid hormone using a microprojection array
WO2023042889A1 (ja) 2021-09-15 2023-03-23 コスメディ製薬株式会社 薬剤を塗布したマイクロニードルアレイ

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2612005C (en) * 2005-06-17 2013-10-29 Georgia Tech Research Corporation Coated microstructures and method of manufacture thereof
US9067048B2 (en) 2009-04-24 2015-06-30 Medrx Co., Ltd. Medication liquid supporting jig and method of applying medication to micro-needle using same
US8834423B2 (en) 2009-10-23 2014-09-16 University of Pittsburgh—of the Commonwealth System of Higher Education Dissolvable microneedle arrays for transdermal delivery to human skin
WO2011105496A1 (ja) 2010-02-24 2011-09-01 久光製薬株式会社 マイクロニードルデバイス
EP2575845B1 (en) * 2010-05-28 2017-02-15 3M Innovative Properties Company Aqueous formulations for coating microneedle arrays
WO2012056702A1 (ja) * 2010-10-27 2012-05-03 株式会社メドレックス マイクロニードルの塗布方法
EP2497463A1 (en) * 2011-03-09 2012-09-12 Rogier Biemans Method of protecting biologically active substances against denaturation
NL2007382C2 (en) 2011-09-09 2013-03-12 Univ Leiden Method to coat an active agent to a surface.
GB201116143D0 (en) 2011-09-16 2011-11-02 Univ Greenwich Method of coating microneedle devices
JP6265740B2 (ja) 2011-10-06 2018-01-24 久光製薬株式会社 アプリケータ
EP2841147A4 (en) 2012-05-01 2016-04-13 Univ Pittsburgh MICRO-NEEDLES NETWORKS WITH CHARGED END FOR TRANSDERMAL INSERTION
CA2889500A1 (en) * 2012-11-02 2014-05-08 Cosmed Pharmaceutical Co., Ltd. Retinoic acid microneedle
ITMI20130586A1 (it) * 2013-04-11 2014-10-12 Azienda Ospedaliero Universitaria P Isana Microago e matrice di microaghi per uso medicale, e processo di produzione di detta matrice
JP6110485B2 (ja) * 2013-05-29 2017-04-05 久光製薬株式会社 マイクロニードル製剤製造用システム及び空調方法
GB201317641D0 (en) * 2013-10-05 2013-11-20 Chowdhury Dewan F H Novel solid dosage form
US20160279401A1 (en) 2015-03-27 2016-09-29 Allergan, Inc. Dissolvable microneedles for skin treatment
WO2016149673A1 (en) 2015-03-18 2016-09-22 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Bioactive components conjugated to substrates of microneedle arrays
US10172558B2 (en) 2015-09-10 2019-01-08 University Of Utah Research Foundation Structure and methodology for a shadow mask having hollow high aspect ratio projections
US11684763B2 (en) 2015-10-16 2023-06-27 University of Pittsburgh—of the Commonwealth System of Higher Education Multi-component bio-active drug delivery and controlled release to the skin by microneedle array devices
KR20180087252A (ko) * 2015-11-27 2018-08-01 주식회사 라보 쥬?사 마이크로 니들 및 그 제조 방법
WO2017120322A1 (en) 2016-01-05 2017-07-13 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Skin microenvironment targeted delivery for promoting immune and other responses
US20170209553A1 (en) * 2016-01-22 2017-07-27 Transderm, Inc. Delivery of botulinum with microneedle arrays
KR101798326B1 (ko) * 2016-04-07 2017-11-15 가천대학교 산학협력단 코팅 마이크로 니들 제조장치
US20200306518A1 (en) 2016-05-20 2020-10-01 Uprax Microsolutions B.V. System and method for applying microneedles
US20180056053A1 (en) * 2016-08-26 2018-03-01 Juvic Inc. Protruding microstructure for transdermal delivery
WO2018151832A1 (en) 2017-02-17 2018-08-23 Allergan, Inc. Microneedle array with active ingredient
KR102033686B1 (ko) * 2017-05-19 2019-10-18 보령제약 주식회사 도네페질을 함유하는 마이크로니들 경피 패치
KR102526228B1 (ko) * 2018-05-23 2023-04-26 후지필름 가부시키가이샤 일본 뇌염 백신 함유 마이크로니들 어레이
CN115337530A (zh) * 2022-09-05 2022-11-15 安徽中医药大学 一种秋水仙碱水凝胶微针及其制备方法

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001506904A (ja) 1996-12-20 2001-05-29 アルザ・コーポレーション 経皮作用剤流量を強化するための組成物と方法
WO2002074173A1 (en) 2001-03-16 2002-09-26 Alza Corporation Method and apparatus for coating skin piercing microprojections
JP2004504120A (ja) 2000-07-21 2004-02-12 グラクソスミスクライン　バイオロジカルズ　ソシエテ　アノニム ワクチン
JP2004520152A (ja) 2000-10-26 2004-07-08 アルザ・コーポレーシヨン 被覆された微細突出物を有する経皮的薬剤配達装置
JP2005074139A (ja) * 2003-09-03 2005-03-24 Toto Ltd 医療用品用コーティング組成物
WO2005044366A2 (en) * 2003-10-31 2005-05-19 Alza Corporation System and method for transdermal vaccine delivery
WO2006055799A1 (en) 2004-11-18 2006-05-26 3M Innovative Properties Company Masking method for coating a microneedle array
WO2006138719A2 (en) 2005-06-17 2006-12-28 Georgia Tech Research Corporation Coated microstructures and method of manufacture thereof
JP2007075352A (ja) * 2005-09-14 2007-03-29 Olympus Corp 医療用コーティング剤並びに医療用部材及びその製造方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11286439A (ja) 1998-04-01 1999-10-19 Senju Pharmaceut Co Ltd 生分解性ポリマー型薬物放出システム
US20050123550A1 (en) * 2003-05-12 2005-06-09 Laurent Philippe E. Molecules enhancing dermal delivery of influenza vaccines
US8771781B2 (en) 2007-05-15 2014-07-08 Hisamitsu Pharmaceutical Co., Inc. Method of coating microneedle

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001506904A (ja) 1996-12-20 2001-05-29 アルザ・コーポレーション 経皮作用剤流量を強化するための組成物と方法
JP2004504120A (ja) 2000-07-21 2004-02-12 グラクソスミスクライン　バイオロジカルズ　ソシエテ　アノニム ワクチン
JP2004520152A (ja) 2000-10-26 2004-07-08 アルザ・コーポレーシヨン 被覆された微細突出物を有する経皮的薬剤配達装置
WO2002074173A1 (en) 2001-03-16 2002-09-26 Alza Corporation Method and apparatus for coating skin piercing microprojections
JP2005074139A (ja) * 2003-09-03 2005-03-24 Toto Ltd 医療用品用コーティング組成物
WO2005044366A2 (en) * 2003-10-31 2005-05-19 Alza Corporation System and method for transdermal vaccine delivery
WO2006055799A1 (en) 2004-11-18 2006-05-26 3M Innovative Properties Company Masking method for coating a microneedle array
WO2006138719A2 (en) 2005-06-17 2006-12-28 Georgia Tech Research Corporation Coated microstructures and method of manufacture thereof
JP2007075352A (ja) * 2005-09-14 2007-03-29 Olympus Corp 医療用コーティング剤並びに医療用部材及びその製造方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP2153863A4

Cited By (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9114238B2 (en) 2007-04-16 2015-08-25 Corium International, Inc. Solvent-cast microprotrusion arrays containing active ingredient
US10238848B2 (en) 2007-04-16 2019-03-26 Corium International, Inc. Solvent-cast microprotrusion arrays containing active ingredient
US9498524B2 (en) 2007-04-16 2016-11-22 Corium International, Inc. Method of vaccine delivery via microneedle arrays
US9452280B2 (en) 2007-04-16 2016-09-27 Corium International, Inc. Solvent-cast microprotrusion arrays containing active ingredient
US8771781B2 (en) 2007-05-15 2014-07-08 Hisamitsu Pharmaceutical Co., Inc. Method of coating microneedle
WO2009008951A3 (en) * 2007-07-09 2010-03-04 Apogee Technology, Inc. Methods and systems for coating a microneedle with a dosage of a biologically active compound
WO2009008951A2 (en) * 2007-07-09 2009-01-15 Apogee Technology, Inc. Methods and systems for coating a microneedle with a dosage of a biologically active compound
JPWO2010074239A1 (ja) * 2008-12-26 2012-06-21 久光製薬株式会社 マイクロニードルデバイス
CN102264429A (zh) * 2008-12-26 2011-11-30 久光制药株式会社 微针装置
WO2010074239A1 (ja) * 2008-12-26 2010-07-01 久光製薬株式会社 マイクロニードルデバイス
JP5902390B2 (ja) * 2008-12-26 2016-04-13 久光製薬株式会社 マイクロニードルデバイス
KR101634836B1 (ko) * 2008-12-26 2016-06-29 히사미쓰 세이야꾸 가부시키가이샤 마이크로 니들 디바이스
US20110288485A1 (en) * 2008-12-26 2011-11-24 Hisamitsu Pharmaceutical Co., Inc. Microneedle device
KR20110107333A (ko) * 2008-12-26 2011-09-30 히사미쓰 세이야꾸 가부시키가이샤 마이크로 니들 디바이스
WO2010087300A1 (ja) * 2009-01-30 2010-08-05 久光製薬株式会社 マイクロニードルデバイス
KR101634838B1 (ko) 2009-01-30 2016-06-29 히사미쓰 세이야꾸 가부시키가이샤 마이크로 니들 디바이스
JP5709530B2 (ja) * 2009-01-30 2015-04-30 久光製薬株式会社 マイクロニードルデバイス
KR20110118627A (ko) * 2009-01-30 2011-10-31 히사미쓰 세이야꾸 가부시키가이샤 마이크로 니들 디바이스
JP2012524637A (ja) * 2009-04-24 2012-10-18 コリウム インターナショナル， インコーポレイテッド マイクロプロジェクションのアレイの製造のためのプロセス
JPWO2010143689A1 (ja) * 2009-06-10 2012-11-29 久光製薬株式会社 マイクロニードルデバイス
EP2441437A4 (en) * 2009-06-10 2013-05-01 Hisamitsu Pharmaceutical Co MICRO NEEDLE DEVICE
WO2010143689A1 (ja) * 2009-06-10 2010-12-16 久光製薬株式会社 マイクロニードルデバイス
JP5615814B2 (ja) * 2009-06-10 2014-10-29 久光製薬株式会社 マイクロニードルデバイス
EP2441437A1 (en) * 2009-06-10 2012-04-18 Hisamitsu Pharmaceutical Co., Inc. Microneedle device
US8747362B2 (en) 2009-06-10 2014-06-10 Hisamitsu Pharmaceutical Co., Inc Microneedle device
US8696638B2 (en) 2009-07-23 2014-04-15 Hisamitsu Pharmaceutical Co., Inc. Microneedle array
JP2011224308A (ja) * 2010-04-21 2011-11-10 Kosumedei Seiyaku Kk マイクロニードル溶着法
US11419816B2 (en) 2010-05-04 2022-08-23 Corium, Inc. Method and device for transdermal delivery of parathyroid hormone using a microprojection array
WO2012066506A2 (en) 2010-11-18 2012-05-24 University College Cork Method
US20180344631A1 (en) * 2011-03-07 2018-12-06 3M Innovative Properties Company Microneedle devices and methods
JP2017105784A (ja) * 2011-03-07 2017-06-15 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードルデバイス及び方法
JP2014507473A (ja) * 2011-03-07 2014-03-27 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードルデバイス及び方法
JP2014514022A (ja) * 2011-03-07 2014-06-19 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードルデバイス及び方法
US20140066843A1 (en) * 2011-03-07 2014-03-06 3M Innovative Properties Company Microneedle devices and methods
US20140066842A1 (en) * 2011-03-07 2014-03-06 3M Innovative Properties Company Microneedle devices and methods
JPWO2012128363A1 (ja) * 2011-03-24 2014-07-24 コスメディ製薬株式会社 Ｐｅｄｆマイクロニードルアレイ及びその製造方法
WO2012128363A1 (ja) * 2011-03-24 2012-09-27 コスメディ製薬株式会社 Ｐｅｄｆマイクロニードルアレイ及びその製造方法
JP2013043035A (ja) * 2011-08-26 2013-03-04 Dainippon Printing Co Ltd マイクロニードルデバイスの製造方法
JP2013043034A (ja) * 2011-08-26 2013-03-04 Dainippon Printing Co Ltd マイクロニードルデバイスの製造方法
KR101931845B1 (ko) * 2011-10-20 2018-12-21 코스메드 파마소티컬 씨오 쩜 엘티디 마이크로니들 용착법
WO2013057819A1 (ja) * 2011-10-20 2013-04-25 コスメディ製薬株式会社 マイクロニードル溶着法
EP2769749A4 (en) * 2011-10-20 2015-05-06 Cosmed Pharmaceutical Co Ltd MICRO NEEDLE CAPTURE TECHNOLOGY
US9993423B2 (en) 2011-10-20 2018-06-12 Cosmed Pharmaceutical Co., Ltd. Microneedle deposition method
JP2013177376A (ja) * 2012-02-09 2013-09-09 Hisamitsu Pharmaceut Co Inc マイクロニードル用ゾルミトリプタン含有コーティング組成物及びマイクロニードルデバイス
KR20200062377A (ko) 2012-02-17 2020-06-03 코스메드 파마소티컬 씨오 쩜 엘티디 단시간 용해형 마이크로니들
WO2013122160A1 (ja) 2012-02-17 2013-08-22 コスメディ製薬株式会社 短時間溶解型マイクロニードル
JP2012158607A (ja) * 2012-05-02 2012-08-23 Kosumedei Seiyaku Kk マイクロニードル溶着法
JP2013094662A (ja) * 2012-05-02 2013-05-20 Kosumedei Seiyaku Kk マイクロニードル溶着法
US11052231B2 (en) 2012-12-21 2021-07-06 Corium, Inc. Microarray for delivery of therapeutic agent and methods of use
US10994111B2 (en) 2013-02-14 2021-05-04 Cosmed Pharmaceutical Co., Ltd. Drug-holding microneedle array and manufacturing method thereof
US11110259B2 (en) 2013-03-12 2021-09-07 Corium, Inc. Microprojection applicators and methods of use
US10245422B2 (en) 2013-03-12 2019-04-02 Corium International, Inc. Microprojection applicators and methods of use
US9962534B2 (en) 2013-03-15 2018-05-08 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
US11565097B2 (en) 2013-03-15 2023-01-31 Corium Pharma Solutions, Inc. Microarray for delivery of therapeutic agent and methods of use
US10384046B2 (en) 2013-03-15 2019-08-20 Corium, Inc. Microarray for delivery of therapeutic agent and methods of use
US10384045B2 (en) 2013-03-15 2019-08-20 Corium, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
US10195409B2 (en) 2013-03-15 2019-02-05 Corium International, Inc. Multiple impact microprojection applicators and methods of use
WO2014192890A1 (ja) 2013-05-29 2014-12-04 久光製薬株式会社 マイクロニードル製剤製造用システム及び空調方法
US11130148B2 (en) 2013-05-29 2021-09-28 Hisamitsu Pharmaceutical Co., Inc. System for manufacturing microneedle preparation, and air-conditioning method
US10500386B2 (en) 2013-07-30 2019-12-10 Asti Corporation Microneedle array manufacturing method
JPWO2015016235A1 (ja) * 2013-07-30 2017-03-02 Ａｓｔｉ株式会社 マイクロニードルアレイとマイクロニードルアレイ製造方法
WO2015016235A1 (ja) * 2013-07-30 2015-02-05 Ａｓｔｉ株式会社 マイクロニードルアレイとマイクロニードルアレイ製造方法
US10624843B2 (en) 2014-09-04 2020-04-21 Corium, Inc. Microstructure array, methods of making, and methods of use
US10857093B2 (en) 2015-06-29 2020-12-08 Corium, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
WO2017135290A1 (ja) * 2016-02-03 2017-08-10 コスメディ製薬株式会社 マイクロニードル用塗布液、マイクロニードル塗布物、及びマイクロニードルアレイ
US11045417B2 (en) 2016-02-03 2021-06-29 Cosmed Pharmaceutical Co., Ltd. Coating liquid for microneedles, microneedle-coating substance, and microneedle array
JP2017137311A (ja) * 2016-02-03 2017-08-10 コスメディ製薬株式会社 マイクロニードル塗布物
WO2019088315A1 (ko) * 2017-11-01 2019-05-09 주식회사 엘지생활건강 탈모 방지제 및 발모 치료제 전달을 위한 용해성 미세바늘 패치
WO2023042889A1 (ja) 2021-09-15 2023-03-23 コスメディ製薬株式会社 薬剤を塗布したマイクロニードルアレイ

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