JP6265740B2 - アプリケータ - Google Patents
アプリケータ Download PDFInfo
- Publication number
- JP6265740B2 JP6265740B2 JP2013537516A JP2013537516A JP6265740B2 JP 6265740 B2 JP6265740 B2 JP 6265740B2 JP 2013537516 A JP2013537516 A JP 2013537516A JP 2013537516 A JP2013537516 A JP 2013537516A JP 6265740 B2 JP6265740 B2 JP 6265740B2
- Authority
- JP
- Japan
- Prior art keywords
- piston
- applicator
- spring
- microneedle array
- transmission member
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
- A61B5/15101—Details
- A61B5/15115—Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids
- A61B5/15117—Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids comprising biased elements, resilient elements or a spring, e.g. a helical spring, leaf spring, or elastic strap
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150977—Arrays of piercing elements for simultaneous piercing
- A61B5/150984—Microneedles or microblades
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0023—Drug applicators using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0046—Solid microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0061—Methods for using microneedles
Description
Claims (4)
- 皮膚にマイクロニードルを適用させるためのアプリケータであって、
針密度が566本/cm 2 である前記マイクロニードルを有するマイクロニードルアレイに付勢部材の付勢力を伝える伝達部材を備え、
前記伝達部材の質量が0.9802g以上1.1906g以下であり、
前記付勢部材の付勢力により作動した前記伝達部材の運動量が0.0083(Ns)以上0.015(Ns)以下である、アプリケータ。 - 前記付勢部材が弾性部材であり、
前記皮膚に向かって移動する前記伝達部材の移動区間の一部である第1の区間において、該伝達部材が前記弾性部材の付勢力を受けることなく移動する、請求項1に記載のアプリケータ。 - 前記弾性部材を支持するとともに、前記第1の区間とは異なる第2の区間において前記付勢力を前記伝達部材に伝える支持台をさらに備え、
前記付勢力により前記伝達部材を押していた前記支持台が前記第2の区間の一端において止まることで、該伝達部材が前記第1の区間において前記付勢力を受けることなく移動する、請求項2に記載のアプリケータ。 - 前記付勢部材は円柱コイルばねである、請求項1〜3のいずれか一項に記載のアプリケータ。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2011222236 | 2011-10-06 | ||
JP2011222236 | 2011-10-06 | ||
PCT/JP2012/075534 WO2013051568A1 (ja) | 2011-10-06 | 2012-10-02 | アプリケータ |
Publications (2)
Publication Number | Publication Date |
---|---|
JPWO2013051568A1 JPWO2013051568A1 (ja) | 2015-03-30 |
JP6265740B2 true JP6265740B2 (ja) | 2018-01-24 |
Family
ID=48043725
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2013537516A Active JP6265740B2 (ja) | 2011-10-06 | 2012-10-02 | アプリケータ |
Country Status (5)
Country | Link |
---|---|
US (1) | US9498611B2 (ja) |
EP (1) | EP2764887B1 (ja) |
JP (1) | JP6265740B2 (ja) |
TW (1) | TW201330893A (ja) |
WO (1) | WO2013051568A1 (ja) |
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WO2013053022A1 (en) | 2011-10-12 | 2013-04-18 | The University Of Queensland | Delivery device |
JP6226862B2 (ja) * | 2012-04-05 | 2017-11-08 | 久光製薬株式会社 | 穿刺装置及びその製造方法 |
EP2937111B1 (en) | 2012-12-21 | 2020-03-18 | Hisamitsu Pharmaceutical Co., Inc. | Applicator |
SG11201509722PA (en) * | 2013-05-31 | 2015-12-30 | 3M Innovative Properties Co | Microneedle injection apparatus comprising a dual cover |
BR112016002695B1 (pt) * | 2013-08-09 | 2022-09-20 | Cytrellis Biosystems, Inc | Dispositivo com um aparelho ablativo, um aparelho de remoção e um aparelho de posicionamento |
CA2924447C (en) * | 2013-09-18 | 2020-08-04 | Cosmed Pharmaceutical Co., Ltd. | Microneedle patch application device and patch holder |
EP3067088B1 (en) | 2013-11-05 | 2019-09-04 | Hisamitsu Pharmaceutical Co., Inc. | Applicator |
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CA2975275C (en) | 2015-02-02 | 2023-08-29 | Vaxxas Pty Limited | Microprojection array applicator and method |
JP2017023404A (ja) * | 2015-07-22 | 2017-02-02 | 日本写真印刷株式会社 | マイクロニードルパッチ用インパクト付加型アプリケータ及び先端部材 |
WO2017038499A1 (ja) * | 2015-09-02 | 2017-03-09 | 久光製薬株式会社 | アプリケータ |
WO2017045031A1 (en) | 2015-09-18 | 2017-03-23 | Vaxxas Pty Limited | Microprojection arrays with microprojections having large surface area profiles |
US20180264244A1 (en) * | 2015-09-28 | 2018-09-20 | Vaxxas Pty Limited | Microprojection arrays with enhanced skin penetrating properties and methods thereof |
EP4306803A3 (en) | 2017-03-31 | 2024-04-10 | Vaxxas Pty Limited | Device and method for coating surfaces |
US11175128B2 (en) | 2017-06-13 | 2021-11-16 | Vaxxas Pty Limited | Quality control of substrate coatings |
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USD1023303S1 (en) * | 2021-12-08 | 2024-04-16 | Guangzhou Ekai Electronic Technology Co., Ltd. | Microneedling pen |
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-
2012
- 2012-10-02 JP JP2013537516A patent/JP6265740B2/ja active Active
- 2012-10-02 EP EP12838997.0A patent/EP2764887B1/en active Active
- 2012-10-02 WO PCT/JP2012/075534 patent/WO2013051568A1/ja active Application Filing
- 2012-10-02 US US14/349,523 patent/US9498611B2/en active Active
- 2012-10-04 TW TW101136676A patent/TW201330893A/zh unknown
Also Published As
Publication number | Publication date |
---|---|
WO2013051568A1 (ja) | 2013-04-11 |
EP2764887B1 (en) | 2020-12-02 |
JPWO2013051568A1 (ja) | 2015-03-30 |
TW201330893A (zh) | 2013-08-01 |
US9498611B2 (en) | 2016-11-22 |
US20140243747A1 (en) | 2014-08-28 |
EP2764887A4 (en) | 2015-12-09 |
TWI561272B (ja) | 2016-12-11 |
EP2764887A1 (en) | 2014-08-13 |
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