WO2008096732A1 - アレルギー診断用マイクロニードルデバイス - Google Patents

アレルギー診断用マイクロニードルデバイス Download PDF

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Publication number
WO2008096732A1
WO2008096732A1 PCT/JP2008/051825 JP2008051825W WO2008096732A1 WO 2008096732 A1 WO2008096732 A1 WO 2008096732A1 JP 2008051825 W JP2008051825 W JP 2008051825W WO 2008096732 A1 WO2008096732 A1 WO 2008096732A1
Authority
WO
WIPO (PCT)
Prior art keywords
allergy
diagnosis
microneedle device
microneedles
microneedle
Prior art date
Application number
PCT/JP2008/051825
Other languages
English (en)
French (fr)
Inventor
Seiji Tokumoto
Toshiyuki Matsudo
Tetsuji Kuwahara
Original Assignee
Hisamitsu Pharmaceutical Co., Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hisamitsu Pharmaceutical Co., Inc. filed Critical Hisamitsu Pharmaceutical Co., Inc.
Priority to ES08704452.5T priority Critical patent/ES2473620T3/es
Priority to US12/525,818 priority patent/US20100030100A1/en
Priority to EP08704452.5A priority patent/EP2119469B1/en
Priority to JP2008557112A priority patent/JP5241517B2/ja
Publication of WO2008096732A1 publication Critical patent/WO2008096732A1/ja

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0035—Vaccination diagnosis other than by injuring the skin, e.g. allergy test patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Surgical Instruments (AREA)

Abstract

　アレルギー診断において簡便な操作で鮮明な皮膚判定を短時間で行うことができる安価なアレルギー診断用マイクロニードルデバイスを提供する。マイクロニードルデバイス（１）は、マイクロニードル基板（２）と、基板上に設けられ皮膚を穿孔可能な長さが５０μｍ～５００μｍで密度が１ｃｍ２当たり１００ないし１００００本のマイクロニードル（３）と、マイクロニードル上に設けられ少なくとも１種類のアレルギー抗原を保持するアレルギー抗原保持手段（４）とを備える。マイクロニードル（３）は非金属製の合成または天然の樹脂素材を用いて作製することができる。
PCT/JP2008/051825 2007-02-06 2008-02-05 アレルギー診断用マイクロニードルデバイス WO2008096732A1 (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
ES08704452.5T ES2473620T3 (es) 2007-02-06 2008-02-05 Dispositivo de microagujas para el diagnóstico de una alergia
US12/525,818 US20100030100A1 (en) 2007-02-06 2008-02-05 Microneedle Device For Diagnosis Of Allergy
EP08704452.5A EP2119469B1 (en) 2007-02-06 2008-02-05 Microneedle device for diagnosis of allergy
JP2008557112A JP5241517B2 (ja) 2007-02-06 2008-02-05 アレルギー診断用マイクロニードルデバイス

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-026650 2007-02-06
JP2007026650 2007-02-06

Publications (1)

Publication Number Publication Date
WO2008096732A1 true WO2008096732A1 (ja) 2008-08-14

Family

ID=39681641

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/051825 WO2008096732A1 (ja) 2007-02-06 2008-02-05 アレルギー診断用マイクロニードルデバイス

Country Status (5)

Country Link
US (1) US20100030100A1 (ja)
EP (1) EP2119469B1 (ja)
JP (1) JP5241517B2 (ja)
ES (1) ES2473620T3 (ja)
WO (1) WO2008096732A1 (ja)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010069252A (ja) * 2008-09-22 2010-04-02 Fujifilm Corp 経皮吸収シートの製造方法
WO2010040271A1 (en) * 2008-10-07 2010-04-15 Tuo Jin Phase-transition polymeric microneedles
JP2010082401A (ja) * 2008-09-29 2010-04-15 Kosumedei Seiyaku Kk マイクロニードルアレイ
WO2010143689A1 (ja) * 2009-06-10 2010-12-16 久光製薬株式会社 マイクロニードルデバイス
JP2013162861A (ja) * 2012-02-10 2013-08-22 Bioserentack Co Ltd 細胞間液モニター用マイクロニードル
US8696638B2 (en) 2009-07-23 2014-04-15 Hisamitsu Pharmaceutical Co., Inc. Microneedle array
JP5709530B2 (ja) * 2009-01-30 2015-04-30 久光製薬株式会社 マイクロニードルデバイス
JP2019528108A (ja) * 2016-08-12 2019-10-10 プロラゲン カンパニー リミテッド マイクロニードルパッチ、この製造方法及びこれをアレルギー疾患診断のために操作する方法
KR102122208B1 (ko) * 2020-04-07 2020-06-12 주식회사 라파스 마이크로니들 패치를 이용한 최소 침습적 아토피 피부염 검사 방법 및 마이크로니들 패치를 포함하는 최소 침습적 아토피 검사 키트

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010074239A1 (ja) * 2008-12-26 2010-07-01 久光製薬株式会社 マイクロニードルデバイス
KR101728194B1 (ko) * 2010-02-24 2017-05-02 히사미쓰 세이야꾸 가부시키가이샤 마이크로 니들 디바이스 및 그 제조 방법
WO2011105496A1 (ja) 2010-02-24 2011-09-01 久光製薬株式会社 マイクロニードルデバイス
US9693950B2 (en) * 2010-05-28 2017-07-04 3M Innovative Properties Company Aqueous formulations for coating microneedle arrays
US10244981B2 (en) * 2011-03-30 2019-04-02 SensiVida Medical Technologies, Inc. Skin test image analysis apparatuses and methods thereof
WO2012145665A2 (en) * 2011-04-22 2012-10-26 Radius Health, Inc. Method of drug delivery for pth, pthrp and related peptides
EP2726866A1 (en) * 2011-06-29 2014-05-07 Hds Limited An improved micropatch for assessing chemical contact allergy
GB2492361A (en) * 2011-06-29 2013-01-02 Hds Ltd Micropatch for contact allergy testing
GB201116143D0 (en) * 2011-09-16 2011-11-02 Univ Greenwich Method of coating microneedle devices
US9498611B2 (en) 2011-10-06 2016-11-22 Hisamitsu Pharmaceutical Co., Inc. Applicator
US9011350B2 (en) 2011-11-30 2015-04-21 Lincoln Diagnostics, Inc. Allergy testing device and method of testing for allergies
US8469900B2 (en) * 2011-11-30 2013-06-25 Lincoln Diagnostics, Inc. Allergy testing device and method of testing for allergies
KR102216949B1 (ko) 2012-12-14 2021-02-22 민데라 코포레이션 바이오마커의 검출 및 취득을 위한 방법 및 디바이스
JP6110562B2 (ja) * 2013-05-06 2017-04-05 ユービック インコーポレイテッド 遠心力を利用したマイクロ構造体の製造方法およびそれから製造されたマイクロ構造体
WO2014182932A1 (en) * 2013-05-08 2014-11-13 The Board Of Trustees Of The Leland Stanford Junior University Methods of testing for allergen sensitivity
IL310069A (en) 2015-04-29 2024-03-01 Radius Pharmaceuticals Inc Cancer treatment methods
CN105078880A (zh) * 2015-09-12 2015-11-25 北京化工大学 一种用于多肽和蛋白质类药物透皮给药的高分子可溶微针及其制备方法
WO2018129419A1 (en) 2017-01-05 2018-07-12 Radius Pharmaceuticals, Inc. Polymorphic forms of rad1901-2hcl
SG11202013177WA (en) 2018-07-04 2021-01-28 Radius Pharmaceuticals Inc Polymorphic forms of rad 1901-2hcl
US20230148946A1 (en) * 2020-03-27 2023-05-18 Aquavit Pharmaceuticals, Inc. Methods of detecting allergic reactions in subjects using microchannel delivery devices
US11931537B2 (en) 2020-10-05 2024-03-19 SensiVida Medical Technologies Inc. Practice-loadable minimally invasive allergy test system

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58131919A (ja) 1981-12-14 1983-08-06 ニコラス・エツチ・マガニアス アレルギ−テスト方法とそのテスト片
JP2506543B2 (ja) 1992-01-22 1996-06-12 ベクトン・ディッキンソン・アンド・カンパニー イオントフォレ―シスによる送達のための分子
JP2002535100A (ja) 1999-01-28 2002-10-22 サイト パルス サイエンシズ、インコーポレイテッド 細胞内への巨大分子の送達
JP2004028900A (ja) * 2002-06-27 2004-01-29 Japan Science & Technology Corp 赤外光集光装置
JP2004528900A (ja) 2001-04-20 2004-09-24 アルザ・コーポレーシヨン 有益な作用物質を含有するコーティングを有する微小突起アレイ

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6713291B2 (en) * 1999-01-28 2004-03-30 Alan D. King Electrodes coated with treating agent and uses thereof
WO2002064193A2 (en) * 2000-12-14 2002-08-22 Georgia Tech Research Corporation Microneedle devices and production thereof
EP1439870B1 (en) * 2001-10-29 2009-01-14 Becton, Dickinson and Company Device for the delivery of a substance
WO2003051454A2 (en) * 2001-12-14 2003-06-26 Genetronics, Inc. Methods for particle-assisted polynucleotide immunization using a pulsed electric field
JP4307269B2 (ja) * 2002-04-25 2009-08-05 ガバ・インテルナツィオナール・アクチェンゲゼルシャフト オボムチンを含有する口腔ケア組成物
US7591806B2 (en) * 2004-05-18 2009-09-22 Bai Xu High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances
US8512736B2 (en) * 2005-09-21 2013-08-20 Surmodics, Inc. Coatings including natural biodegradable polysaccharides and uses thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58131919A (ja) 1981-12-14 1983-08-06 ニコラス・エツチ・マガニアス アレルギ−テスト方法とそのテスト片
JP2506543B2 (ja) 1992-01-22 1996-06-12 ベクトン・ディッキンソン・アンド・カンパニー イオントフォレ―シスによる送達のための分子
JP2002535100A (ja) 1999-01-28 2002-10-22 サイト パルス サイエンシズ、インコーポレイテッド 細胞内への巨大分子の送達
JP2004528900A (ja) 2001-04-20 2004-09-24 アルザ・コーポレーシヨン 有益な作用物質を含有するコーティングを有する微小突起アレイ
JP2004028900A (ja) * 2002-06-27 2004-01-29 Japan Science & Technology Corp 赤外光集光装置

Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010069252A (ja) * 2008-09-22 2010-04-02 Fujifilm Corp 経皮吸収シートの製造方法
JP2010082401A (ja) * 2008-09-29 2010-04-15 Kosumedei Seiyaku Kk マイクロニードルアレイ
WO2010040271A1 (en) * 2008-10-07 2010-04-15 Tuo Jin Phase-transition polymeric microneedles
US9320878B2 (en) 2008-10-07 2016-04-26 Tuo Jin Phase-transition polymeric microneedles
JP2012505164A (ja) * 2008-10-07 2012-03-01 ジン・トゥオ 相転移重合体マイクロニードル
JP5709530B2 (ja) * 2009-01-30 2015-04-30 久光製薬株式会社 マイクロニードルデバイス
EP2441437A4 (en) * 2009-06-10 2013-05-01 Hisamitsu Pharmaceutical Co MICRO NEEDLE DEVICE
JPWO2010143689A1 (ja) * 2009-06-10 2012-11-29 久光製薬株式会社 マイクロニードルデバイス
CN102458359A (zh) * 2009-06-10 2012-05-16 久光制药株式会社 微针装置
US8747362B2 (en) 2009-06-10 2014-06-10 Hisamitsu Pharmaceutical Co., Inc Microneedle device
JP5615814B2 (ja) * 2009-06-10 2014-10-29 久光製薬株式会社 マイクロニードルデバイス
EP2441437A1 (en) * 2009-06-10 2012-04-18 Hisamitsu Pharmaceutical Co., Inc. Microneedle device
WO2010143689A1 (ja) * 2009-06-10 2010-12-16 久光製薬株式会社 マイクロニードルデバイス
US8696638B2 (en) 2009-07-23 2014-04-15 Hisamitsu Pharmaceutical Co., Inc. Microneedle array
JP2013162861A (ja) * 2012-02-10 2013-08-22 Bioserentack Co Ltd 細胞間液モニター用マイクロニードル
JP2019528108A (ja) * 2016-08-12 2019-10-10 プロラゲン カンパニー リミテッド マイクロニードルパッチ、この製造方法及びこれをアレルギー疾患診断のために操作する方法
KR102122208B1 (ko) * 2020-04-07 2020-06-12 주식회사 라파스 마이크로니들 패치를 이용한 최소 침습적 아토피 피부염 검사 방법 및 마이크로니들 패치를 포함하는 최소 침습적 아토피 검사 키트
WO2021206218A1 (ko) * 2020-04-07 2021-10-14 주식회사 라파스 마이크로니들 패치를 이용한 최소 침습적 아토피 피부염 검사 방법 및 마이크로니들 패치를 포함하는 최소 침습적 아토피 검사 키트
JP7479726B2 (ja) 2020-04-07 2024-05-09 ラパス カンパニー リミテッド マイクロニードルパッチを用いた最小侵襲的アトピー性皮膚炎の検査方法、及びマイクロニードルパッチを含む最小侵襲的アトピーの検査キット

Also Published As

Publication number Publication date
EP2119469A1 (en) 2009-11-18
US20100030100A1 (en) 2010-02-04
ES2473620T3 (es) 2014-07-07
JP5241517B2 (ja) 2013-07-17
EP2119469B1 (en) 2014-05-14
EP2119469A4 (en) 2011-06-22
JPWO2008096732A1 (ja) 2010-05-20

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