BRPI0517749A - dispositivo de aplicação para aplicar um dispositivo de micro-agulha a uma superfìcie de pele, e, método para usar um dispositivo de aplicação - Google Patents

dispositivo de aplicação para aplicar um dispositivo de micro-agulha a uma superfìcie de pele, e, método para usar um dispositivo de aplicação

Info

Publication number
BRPI0517749A
BRPI0517749A BRPI0517749-9A BRPI0517749A BRPI0517749A BR PI0517749 A BRPI0517749 A BR PI0517749A BR PI0517749 A BRPI0517749 A BR PI0517749A BR PI0517749 A BRPI0517749 A BR PI0517749A
Authority
BR
Brazil
Prior art keywords
application device
micro
applying
skin surface
needle
Prior art date
Application number
BRPI0517749-9A
Other languages
English (en)
Inventor
Adam S Cantor
Franklyn L Frederickson
Peter R Johnson
Ted K Ringsred
Original Assignee
3M Innovative Properties Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3M Innovative Properties Co filed Critical 3M Innovative Properties Co
Publication of BRPI0517749A publication Critical patent/BRPI0517749A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles

Abstract

DISPOSITIVO DE APLICAçãO PARA APLICAR UM DISPOSITIVO DE MICRO-AGULHA A UMA SUPERFìCIE DE PELE, E, MéTODO PARA USAR UM DISPOSITIVO DE APLICAçãO. Um aplicador (100) usado para aplicar arranjos de micro-agulhas (10) a um mamífero. Em particular, um dispositivo de aplicação para aplicar um dispositivo de micro-agulha (120) a uma superficie da pele compreendendo uma lâmina flexível (110) tendo uma área central elevada (115) anexada ao dispositivo de micro-agulha e um membro de suporte na, ou, próximo à periferia da lâmina flexivel, onde a lâmina flexivel é configurada de modo que ela sofra um movimento escalonado na direção ortogonal ao plano principal da lâmina.
BRPI0517749-9A 2004-11-18 2005-11-18 dispositivo de aplicação para aplicar um dispositivo de micro-agulha a uma superfìcie de pele, e, método para usar um dispositivo de aplicação BRPI0517749A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62921504P 2004-11-18 2004-11-18
PCT/US2005/041854 WO2006055795A1 (en) 2004-11-18 2005-11-18 Low-profile microneedle array applicator

Publications (1)

Publication Number Publication Date
BRPI0517749A true BRPI0517749A (pt) 2008-10-21

Family

ID=35809616

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0517749-9A BRPI0517749A (pt) 2004-11-18 2005-11-18 dispositivo de aplicação para aplicar um dispositivo de micro-agulha a uma superfìcie de pele, e, método para usar um dispositivo de aplicação

Country Status (12)

Country Link
US (2) US8267889B2 (pt)
EP (1) EP1833547A1 (pt)
JP (2) JP2008520369A (pt)
KR (2) KR20130026511A (pt)
CN (1) CN101060883B (pt)
AU (1) AU2005306422A1 (pt)
BR (1) BRPI0517749A (pt)
CA (1) CA2587505C (pt)
IL (1) IL183204A (pt)
MX (1) MX2007005813A (pt)
WO (1) WO2006055795A1 (pt)
ZA (1) ZA200705102B (pt)

Families Citing this family (98)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
GB0402131D0 (en) 2004-01-30 2004-03-03 Isis Innovation Delivery method
WO2005094526A2 (en) * 2004-03-24 2005-10-13 Corium International, Inc. Transdermal delivery device
US8267889B2 (en) 2004-11-18 2012-09-18 3M Innovative Properties Company Low-profile microneedle array applicator
US10035008B2 (en) 2005-04-07 2018-07-31 3M Innovative Properties Company System and method for tool feedback sensing
WO2007002523A2 (en) 2005-06-24 2007-01-04 3M Innovative Properties Company Collapsible patch with microneedle array
CA2620943A1 (en) * 2005-09-02 2007-03-08 Iomai Corporation Devices for transcutaneous delivery of vaccines and transdermal delivery of drugs and uses thereof
US9119945B2 (en) * 2006-04-20 2015-09-01 3M Innovative Properties Company Device for applying a microneedle array
KR100886633B1 (ko) * 2006-07-14 2009-03-04 호남석유화학 주식회사 전면부에 피부를 통해 체내로 전달하고자 하는 물질의 수용공간을 갖는 피부 침투용 미세 돌기 장치
EP1884223A1 (en) † 2006-08-04 2008-02-06 IP Randwyck B.V. Wound-stimulating unit
CA2676221C (en) * 2007-01-22 2016-12-20 Corium International, Inc. Applicators for microneedles
KR100893250B1 (ko) * 2007-02-28 2009-04-17 광주과학기술원 능동형 미세바늘 장치
JP4978245B2 (ja) * 2007-03-08 2012-07-18 凸版印刷株式会社 針状体、針状体製造方法および薬物輸送デバイス
GB2448493B (en) 2007-04-16 2009-10-14 Dewan Fazlul Hoque Chowdhury Microneedle transdermal delivery device
EP2146689B1 (en) 2007-04-16 2020-08-12 Corium, Inc. Solvent-cast microneedle arrays containing active
US8911749B2 (en) 2007-04-16 2014-12-16 Corium International, Inc. Vaccine delivery via microneedle arrays
JP5222512B2 (ja) * 2007-09-19 2013-06-26 凸版印刷株式会社 マイクロニードルチップ
JP5178132B2 (ja) * 2007-10-11 2013-04-10 キヤノン株式会社 画像処理システム並びに画像処理方法
KR101013581B1 (ko) * 2008-08-06 2011-02-14 라종주 전기 피부 미용기
WO2010022326A2 (en) * 2008-08-22 2010-02-25 Us Worldmeds Llc Transdermal delivery of apomorphine using microneedles
EP2399643A4 (en) 2009-02-23 2012-08-22 Medrx Co Ltd APPLICATOR FOR MICRO NEEDLE NETWORK
ES2634667T3 (es) * 2009-04-24 2017-09-28 Corium International, Inc. Métodos para fabricar conjuntos de microproyección
JP5663792B2 (ja) * 2009-08-07 2015-02-04 株式会社 メドレックス 剣山型マイクロニードルのアプリケータデバイス
US8834423B2 (en) 2009-10-23 2014-09-16 University of Pittsburgh—of the Commonwealth System of Higher Education Dissolvable microneedle arrays for transdermal delivery to human skin
US20110172637A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Drug delivery device including tissue support structure
US20110172639A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Device and method for delivery of microneedle to desired depth within the skin
US20110172609A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Microneedle component assembly for drug delivery device
US20110172645A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Wearable drug delivery device including integrated pumping and activation elements
US20110172638A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Drug delivery device including multi-functional cover
CN103096970B (zh) 2010-01-22 2016-10-26 株式会社医药处方 用于微针粘附皮肤贴剂的粘附贴剂辅助工具
JPWO2011105496A1 (ja) 2010-02-24 2013-06-20 久光製薬株式会社 マイクロニードルデバイス
JP6327852B2 (ja) 2010-05-04 2018-05-23 コリウム インターナショナル， インコーポレイテッド 微小突起アレイを使用した副甲状腺ホルモンの経皮送達のための方法及びデバイス
ES2734560T3 (es) 2010-05-04 2019-12-10 Corium Int Inc Aplicadores para microagujas
WO2011141426A1 (en) 2010-05-10 2011-11-17 Tt Seed S.R.L. Needle device for detecting biosignals through the skin
WO2012061556A1 (en) 2010-11-03 2012-05-10 Flugen, Inc. Wearable drug delivery device having spring drive and sliding actuation mechanism
CN101972499B (zh) * 2010-11-10 2016-07-06 吉林大学 轻松无痛输药装置
IT1403293B1 (it) 2010-12-27 2013-10-17 Fond Don Carlo Gnocchi Onlus Apparecchiatura ad aghi per la somministrazione transdermica di farmaci.
EP2722072A4 (en) 2011-06-14 2015-02-25 Jong Ju Na DEVICE AND METHOD FOR IMPROVING THE SKIN WITH A RA EFFECT OR AN RA-PLUS EFFECT
US9498611B2 (en) 2011-10-06 2016-11-22 Hisamitsu Pharmaceutical Co., Inc. Applicator
AU2012323392A1 (en) * 2011-10-12 2014-04-24 3M Innovative Properties Company Integrated microneedle array delivery system
JP6305924B2 (ja) * 2011-10-12 2018-04-04 スリーエム イノベイティブ プロパティズ カンパニー 一体化されたマイクロニードルアレイ送達システム
WO2013053022A1 (en) 2011-10-12 2013-04-18 The University Of Queensland Delivery device
US8469900B2 (en) * 2011-11-30 2013-06-25 Lincoln Diagnostics, Inc. Allergy testing device and method of testing for allergies
US9011350B2 (en) 2011-11-30 2015-04-21 Lincoln Diagnostics, Inc. Allergy testing device and method of testing for allergies
DE102011089723A1 (de) 2011-12-23 2013-06-27 Robert Bosch Gmbh Mikronadelarray-Applikator und Verfahren zur Applikation eines Mikronadelarrays
WO2013166162A1 (en) 2012-05-01 2013-11-07 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Tip-loaded microneedle arrays for transdermal insertion
US11318009B2 (en) 2012-05-04 2022-05-03 Lipocosm, Llc Surgical tools and methods for their use
JP5593355B2 (ja) * 2012-07-23 2014-09-24 凸版印刷株式会社 針状体および針状体製造方法
WO2014058746A1 (en) 2012-10-10 2014-04-17 3M Innovative Properties Company Force-controlled applicator for applying a microneedle device to skin
WO2014059104A1 (en) 2012-10-10 2014-04-17 3M Innovative Properties Company Applicator and method for applying a microneedle device to skin
US9789299B2 (en) * 2012-11-16 2017-10-17 3M Innovative Properties Company Force-controlled applicator for applying a microneedle device to skin
AU2013348395A1 (en) 2012-11-21 2015-06-11 Circuit Therapeutics, Inc. System and method for optogenetic therapy
JP6865524B2 (ja) 2012-12-21 2021-04-28 コリウム， インコーポレイテッド 治療剤を送達するためのマイクロアレイおよび使用方法
US10245422B2 (en) 2013-03-12 2019-04-02 Corium International, Inc. Microprojection applicators and methods of use
CA2903583C (en) 2013-03-15 2021-12-28 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
CN105246458B (zh) 2013-03-15 2020-09-15 考里安公司 用于治疗剂递送的微阵列及其使用方法
EP2968116A1 (en) 2013-03-15 2016-01-20 Corium International, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
EP2968751B1 (en) 2013-03-15 2022-11-30 Corium, Inc. Multiple impact microprojection applicators
WO2015017561A1 (en) 2013-07-30 2015-02-05 Zosano Pharma, Inc. Low-profile microneedle patch applicator
CA2925333C (en) 2013-09-30 2021-09-07 Georgia Tech Research Corporation Microneedle patches, systems, and methods
WO2015111672A1 (ja) * 2014-01-24 2015-07-30 凸版印刷株式会社 マイクロニードルユニット
EP3097942A4 (en) * 2014-01-24 2017-09-13 Toppan Printing Co., Ltd. Microneedle unit and microneedle assembly
US10994112B2 (en) 2014-02-05 2021-05-04 Amgen Inc. Drug delivery system with electromagnetic field generator
USD763504S1 (en) 2014-04-02 2016-08-09 Hisamitsu Pharmaceutical Co., Inc. Cosmetic pack sheet
CA3163792A1 (en) 2014-04-24 2015-10-29 Georgia Tech Research Corporation Microneedles and methods of manufacture thereof
WO2016036866A1 (en) 2014-09-04 2016-03-10 Corium International, Inc. Microstructure array, methods of making, and methods of use
WO2016121499A1 (ja) * 2015-01-27 2016-08-04 凸版印刷株式会社 経皮投与デバイス
US11147954B2 (en) * 2015-02-02 2021-10-19 Vaxxas Pty Limited Microprojection array applicator and method
EP3260159A1 (en) 2015-02-13 2017-12-27 MEDRx Co., Ltd. Microneedle insertion device and microneedle patch application device
WO2016149673A1 (en) 2015-03-18 2016-09-22 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Bioactive components conjugated to substrates of microneedle arrays
WO2017004067A1 (en) 2015-06-29 2017-01-05 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
CN108136165B (zh) 2015-09-02 2020-11-06 久光制药株式会社 施放器
US11103259B2 (en) 2015-09-18 2021-08-31 Vaxxas Pty Limited Microprojection arrays with microprojections having large surface area profiles
EP3355981A4 (en) * 2015-09-28 2019-05-22 Vaxxas Pty Limited MICROPROJECTION ARRANGEMENTS WITH IMPROVED SKIN-IMPROPER PROPERTIES AND METHOD THEREFOR
KR101757866B1 (ko) * 2015-10-08 2017-07-14 주식회사 라파스 마이크로니들패치 포장케이스
US11684763B2 (en) 2015-10-16 2023-06-27 University of Pittsburgh—of the Commonwealth System of Higher Education Multi-component bio-active drug delivery and controlled release to the skin by microneedle array devices
WO2017110815A1 (ja) 2015-12-21 2017-06-29 株式会社 メドレックス マイクロニードルパッチアプリケータ及びそのハウジング
WO2017120322A1 (en) 2016-01-05 2017-07-13 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Skin microenvironment targeted delivery for promoting immune and other responses
US10500351B2 (en) * 2016-02-12 2019-12-10 Shawn Michael Michels Aid for subcutaneous tissue injection and process of effecting the injection with the aid
US11577023B2 (en) 2016-12-16 2023-02-14 Sorrento Therapeutics, Inc. Application device for a fluid delivery apparatus and method of use
KR101745445B1 (ko) * 2017-01-25 2017-06-09 송득영 가압형 약물 주입 시스템
ES2960937T3 (es) 2017-03-31 2024-03-07 Vaxxas Pty Ltd Dispositivo y método para recubrir superficies
JP2018191783A (ja) * 2017-05-15 2018-12-06 富士フイルム株式会社 マイクロニードルアレイユニット、および容器
JP2018192177A (ja) * 2017-05-22 2018-12-06 コスメディ製薬株式会社 水溶性化粧用シート保持フィルム
US11175128B2 (en) 2017-06-13 2021-11-16 Vaxxas Pty Limited Quality control of substrate coatings
US11464957B2 (en) 2017-08-04 2022-10-11 Vaxxas Pty Limited Compact high mechanical energy storage and low trigger force actuator for the delivery of microprojection array patches (MAP)
KR20190027233A (ko) * 2017-09-06 2019-03-14 주식회사 라파스 마이크로니들 보호 성능이 개선된 마이크로니들 패치 및 이러한 마이크로니들 패치와 어플리케이터로 구성되는 마이크로니들 패치 어플리케이터 시스템
US10786203B1 (en) * 2018-01-30 2020-09-29 Daniel M. Besser Medical patch applicator device
WO2019166572A1 (en) 2018-02-28 2019-09-06 Pharming Intellectual Property B.V. Pharmaceutical system for transdermal administration of a c1 -esterase inhibitor
US20210008360A1 (en) * 2018-03-13 2021-01-14 Medrx Co., Ltd. Adhesion Member and Microneedle Patch
CN108671385A (zh) * 2018-06-21 2018-10-19 陈宏� 一种穴位自动贴敷直压微针及使用方法
JP1632957S (pt) 2018-10-30 2019-06-03
JP7012171B2 (ja) * 2018-10-31 2022-01-27 富士フイルム株式会社 マイクロニードルアレイデバイス
AU2019414202B2 (en) * 2018-12-25 2024-02-08 Hirosaki University Medicine administering device and medicine administering system
JPWO2021251464A1 (pt) * 2020-06-12 2021-12-16
US11389376B2 (en) 2020-12-21 2022-07-19 Mediccene Inc. Wearable intravenous fluid delivery system
US11672965B2 (en) 2021-09-28 2023-06-13 Biolinq Incorporated Microneedle enclosure and applicator device for microneedle array based continuous analyte monitoring device
US11877848B2 (en) 2021-11-08 2024-01-23 Satio, Inc. Dermal patch for collecting a physiological sample

Family Cites Families (127)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE25637E (en) 1964-09-08 Means for vaccinating
US3123212A (en) 1964-03-03 Multiple disposable intracutaneous injector package
US3072122A (en) 1959-01-15 1963-01-08 Rosenthal Sol Roy Package for transcutaneous injection
US3034507A (en) 1960-05-10 1962-05-15 American Cyanamid Co Intracutaneous injection device
US3136314A (en) 1960-08-01 1964-06-09 Kravitz Harvey Vaccinating devices
US3246647A (en) 1962-07-23 1966-04-19 American Cyanamid Co Disposable intracutaneous injector
US3221740A (en) 1962-08-31 1965-12-07 Rosenthal Sol Roy Injection device
GB1080986A (en) 1964-09-02 1967-08-31 Allen And Hanburys Surgical En Multiple puncture apparatus
US3322121A (en) 1965-11-26 1967-05-30 Oscar H Banker Skin-puncturing unit with a collapsible protective cover
US3510933A (en) 1967-05-26 1970-05-12 American Cyanamid Co Apparatus and method for continuously forming intracutaneous injectors
US3466131A (en) 1967-09-07 1969-09-09 Becton Dickinson Co Dispensing applicator package
US3512520A (en) 1967-11-01 1970-05-19 Michael N Cowan Antigenic test applicator
US3596660A (en) 1969-05-12 1971-08-03 Illinois Tool Works Injection device
US3675766A (en) 1970-02-04 1972-07-11 Sol Roy Rosenthal Multiple puncture injector device
US3688764A (en) 1970-08-20 1972-09-05 Bard Hamilton Co Inc Intracutaneous injection system
US3964482A (en) 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
US3678150A (en) 1971-07-27 1972-07-18 American Cyanamid Co Process for improving the stability of ppd, qt and histoplasmin on tine applicators
DE2250293A1 (de) 1972-10-13 1974-04-25 Bayern Freistaat Impfstempel zur cutanen pockenimpfung mittels trockenimpfstoff
OA05448A (fr) 1975-10-16 1981-03-31 Manufrance Manufacture Francai Dispositif vaccinateur multipénétrant.
US4304241A (en) 1978-09-05 1981-12-08 Aller-Screen, Inc. Skin testing device
US4237906A (en) 1978-12-06 1980-12-09 Havstad Harold R Antigen injection assembly
GB2064329B (en) 1979-11-01 1983-06-22 Matburn Holdings Ltd Multiple puncture apparatus
FR2474856A1 (fr) 1980-01-31 1981-08-07 Merieux Inst Dispositif scarificateur
US4360016A (en) 1980-07-01 1982-11-23 Transidyne General Corp. Blood collecting device
US4503856A (en) 1981-06-29 1985-03-12 Sherwood Medical Company Lancet injector
US4517978A (en) 1983-01-13 1985-05-21 Levin Paul D Blood sampling instrument
US4474751A (en) 1983-05-16 1984-10-02 Merck & Co., Inc. Ophthalmic drug delivery system utilizing thermosetting gels
US4627445A (en) 1985-04-08 1986-12-09 Garid, Inc. Glucose medical monitoring system
GB8710470D0 (en) 1987-05-01 1987-06-03 Mumford Ltd Owen Blood sampling devices
US4850973A (en) 1987-10-16 1989-07-25 Pavel Jordon & Associates Plastic device for injection and obtaining blood samples
US5192535A (en) 1988-02-08 1993-03-09 Insite Vision Incorporated Ophthalmic suspensions
GB2221394B (en) 1988-08-05 1992-03-04 Eilert Eilertsen An injection device
US4924879A (en) 1988-10-07 1990-05-15 Brien Walter J O Blood lancet device
US4920977A (en) 1988-10-25 1990-05-01 Becton, Dickinson And Company Blood collection assembly with lancet and microcollection tube
EP0429842B1 (en) 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Device for the transdermal administration of protein or peptide drug
US5402798A (en) 1991-07-18 1995-04-04 Swierczek; Remi Disposable skin perforator and blood testing device
DE4212315A1 (de) 1992-04-13 1993-10-14 Boehringer Mannheim Gmbh Blutlanzettenvorrichtung zur Entnahme von Blut für Diagnosezwecke
DE4212723C1 (de) * 1992-04-16 1993-11-04 Arta Plast Ab Tyresoe Lanzettenvorrichtung zum punktieren der haut
US5340572A (en) 1993-02-08 1994-08-23 Insite Vision Incorporated Alkaline ophthalmic suspensions
JP2630197B2 (ja) 1993-04-28 1997-07-16 株式会社ニッショー 血液吸出器具
JP2551742B2 (ja) 1994-05-23 1996-11-06 三星電機株式会社 医薬品投与用皮膚傷形成装置
US5487726A (en) 1994-06-16 1996-01-30 Ryder International Corporation Vaccine applicator system
US5636640A (en) * 1995-02-06 1997-06-10 Volunteers For Medical Engineering Liquid sampling and test apparatus
WO1996037256A1 (en) 1995-05-22 1996-11-28 Silicon Microdevices, Inc. Micromechanical patch for enhancing the delivery of compounds through the skin
AU5740496A (en) 1995-05-22 1996-12-11 General Hospital Corporation, The Micromechanical device and method for enhancing delivery of compounds through the skin
DE19525607A1 (de) 1995-07-14 1997-01-16 Boehringer Ingelheim Kg Transcorneales Arzneimittelfreigabesystem
EP0914178B1 (en) * 1996-06-18 2003-03-12 Alza Corporation Device for enhancing transdermal agent delivery or sampling
CA2265906C (en) 1996-09-17 2003-11-11 Deka Products Limited Partnership System for delivery of drugs by transport
US6797276B1 (en) 1996-11-14 2004-09-28 The United States Of America As Represented By The Secretary Of The Army Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response
US5968633A (en) * 1997-06-06 1999-10-19 The Procter & Gamble Company Selectively-activatible sheet material for dispensing and dispersing a substance onto a target surface
EP1037687B8 (en) 1997-12-11 2008-10-22 Alza Corporation Device for enhancing transdermal agent flux
AU739616B2 (en) 1997-12-11 2001-10-18 Alza Corporation Device for enhancing transdermal agent flux
CA2575064C (en) 1997-12-31 2010-02-02 Medtronic Minimed, Inc. Insertion device for an insertion set and method of using the same
US6091975A (en) 1998-04-01 2000-07-18 Alza Corporation Minimally invasive detecting device
CA2229522A1 (en) * 1998-04-15 1999-10-15 Thomas Randall Inkpen Needle aid
US6503231B1 (en) 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
WO1999064580A1 (en) 1998-06-10 1999-12-16 Georgia Tech Research Corporation Microneedle devices and methods of manufacture and use thereof
GB9817662D0 (en) 1998-08-13 1998-10-07 Crocker Peter J Substance delivery
US6532386B2 (en) 1998-08-31 2003-03-11 Johnson & Johnson Consumer Companies, Inc. Electrotransort device comprising blades
US6022368A (en) * 1998-11-30 2000-02-08 Gavronsky; Stas Acupuncture method and device
CN1191872C (zh) 1999-01-28 2005-03-09 塞托·帕尔斯科技公司 运送大分子进入细胞的装置
US6713291B2 (en) 1999-01-28 2004-03-30 Alan D. King Electrodes coated with treating agent and uses thereof
US6611707B1 (en) * 1999-06-04 2003-08-26 Georgia Tech Research Corporation Microneedle drug delivery device
US6743211B1 (en) 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
AU2005200910B2 (en) 1999-06-04 2006-08-03 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6256533B1 (en) 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
US6379324B1 (en) * 1999-06-09 2002-04-30 The Procter & Gamble Company Intracutaneous microneedle array apparatus
US6312612B1 (en) * 1999-06-09 2001-11-06 The Procter & Gamble Company Apparatus and method for manufacturing an intracutaneous microneedle array
US6623457B1 (en) 1999-09-22 2003-09-23 Becton, Dickinson And Company Method and apparatus for the transdermal administration of a substance
US6835184B1 (en) * 1999-09-24 2004-12-28 Becton, Dickinson And Company Method and device for abrading skin
US20020095134A1 (en) 1999-10-14 2002-07-18 Pettis Ronald J. Method for altering drug pharmacokinetics based on medical delivery platform
DE60024312T2 (de) 1999-12-10 2006-08-17 Alza Corp., Mountain View Transdermale Wirkstoffabgabe von makromolekularen Wirkstoffen und Vorrichtung hierfür
JP4312407B2 (ja) 1999-12-10 2009-08-12 アルザ・コーポレーション 持続した経皮による薬物送達のための皮膚処理装置
US6881538B1 (en) 2000-03-05 2005-04-19 3M Innovative Properties Company Array comprising diamond-like glass film
US6595947B1 (en) 2000-05-22 2003-07-22 Becton, Dickinson And Company Topical delivery of vaccines
AU2001275138A1 (en) 2000-06-02 2001-12-17 The University Of Utah Research Foundation Active needle devices with integrated functionality
US6537242B1 (en) * 2000-06-06 2003-03-25 Becton, Dickinson And Company Method and apparatus for enhancing penetration of a member for the intradermal sampling or administration of a substance
US6589202B1 (en) 2000-06-29 2003-07-08 Becton Dickinson And Company Method and apparatus for transdermally sampling or administering a substance to a patient
US6440096B1 (en) 2000-07-14 2002-08-27 Becton, Dickinson And Co. Microdevice and method of manufacturing a microdevice
US6656147B1 (en) * 2000-07-17 2003-12-02 Becton, Dickinson And Company Method and delivery device for the transdermal administration of a substance
GB0017999D0 (en) 2000-07-21 2000-09-13 Smithkline Beecham Biolog Novel device
ES2317940T3 (es) 2000-10-13 2009-05-01 Alza Corporation Dispositivo de retencion para un elemento de microsalientes para aplicador de impactos.
CA2425537C (en) 2000-10-13 2009-09-08 Alza Corporation Microblade array impact applicator
KR20030068136A (ko) * 2000-10-13 2003-08-19 알자 코포레이션 미세 돌기부로 피부를 천공하기 위한 장치 및 방법
US7419481B2 (en) * 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
US7131987B2 (en) 2000-10-16 2006-11-07 Corium International, Inc. Microstructures and method for treating and conditioning skin which cause less irritation during exfoliation
CN1239212C (zh) * 2000-10-26 2006-02-01 阿尔扎公司 具有涂敷的微突出物的经皮肤的给药装置
WO2002045771A2 (en) 2000-11-09 2002-06-13 Biovalve Technologies, Inc. Microneedle adapter
EP2554196B1 (en) 2000-11-30 2018-10-17 Valeritas, Inc. Fluid delivery and measurement systems
WO2002064193A2 (en) 2000-12-14 2002-08-22 Georgia Tech Research Corporation Microneedle devices and production thereof
US20020193729A1 (en) * 2001-04-20 2002-12-19 Cormier Michel J.N. Microprojection array immunization patch and method
CN101129327A (zh) * 2001-04-20 2008-02-27 阿尔扎公司 具有包含有益药剂的涂层的微小突出物阵列
US6591124B2 (en) 2001-05-11 2003-07-08 The Procter & Gamble Company Portable interstitial fluid monitoring system
US7186235B2 (en) 2001-06-08 2007-03-06 Becton, Dickinson And Company Device for manipulating a needle or abrader array and method of use
BR0210628A (pt) 2001-06-29 2004-08-10 Becton Dickinson Co Liberação intradérmica de vacinas e agentes terapêuticos genéticos via microcânula
US6881203B2 (en) 2001-09-05 2005-04-19 3M Innovative Properties Company Microneedle arrays and methods of manufacturing the same
AU2002333554C1 (en) 2001-09-12 2008-12-11 Becton, Dickinson And Company Microneedle-based pen device for drug delivery and method for using same
DE60239229D1 (de) 2001-09-21 2011-03-31 Valeritas Inc Durch gasdruck betätigte mikronadel-anordnungen und damit zusammenhängende systeme und verfahren
US6830562B2 (en) * 2001-09-27 2004-12-14 Unomedical A/S Injector device for placing a subcutaneous infusion set
US7429258B2 (en) 2001-10-26 2008-09-30 Massachusetts Institute Of Technology Microneedle transport device
US6908453B2 (en) 2002-01-15 2005-06-21 3M Innovative Properties Company Microneedle devices and methods of manufacture
US7004928B2 (en) * 2002-02-08 2006-02-28 Rosedale Medical, Inc. Autonomous, ambulatory analyte monitor or drug delivery device
US7858112B2 (en) * 2002-02-28 2010-12-28 Lintec Corporation Percutaneous absorption system and percutaneous absorption method
JP4608187B2 (ja) * 2002-02-28 2011-01-05 リンテック株式会社 経皮吸収型製剤
US6780171B2 (en) 2002-04-02 2004-08-24 Becton, Dickinson And Company Intradermal delivery device
KR101061975B1 (ko) * 2002-06-25 2011-09-05 권성윤 약물 송달 및 다른 용도를 위한 신속 용해형 마이크로 퍼포레이터를 포함하는 어레이
BR0312671A (pt) 2002-07-19 2005-04-26 3M Innovative Properties Co Dispositivo de microagulhas, método para utilizar um dispositivo de microagulhas, e, método para aplicar um dispositivo de microagulhas
CN100479875C (zh) * 2002-07-22 2009-04-22 贝克顿·迪金森公司 贴片状注射装置
ES2537171T3 (es) 2002-08-29 2015-06-03 Becton Dickinson And Company Micro-raspador con características de raspado controladas
AU2004251699A1 (en) 2003-06-04 2005-01-06 Georgia Tech Research Corporation Drilling microneedle device
TW200513280A (en) 2003-07-02 2005-04-16 Alza Corp Microprojection array immunization patch and method
EP2609947B1 (en) 2003-08-12 2020-04-15 Becton, Dickinson and Company Patch-like infusion device
US8353861B2 (en) 2003-09-18 2013-01-15 Texmac, Inc. Applicator for applying functional substances into human skin
AU2004285484A1 (en) 2003-10-24 2005-05-12 Alza Corporation Pretreatment method and system for enhancing transdermal drug delivery
WO2005044139A2 (en) * 2003-10-28 2005-05-19 Alza Corporation Method and apparatus for reducing the incidence of tobacco use
CN100571643C (zh) 2003-10-31 2009-12-23 阿尔扎公司 用于微凸起阵列的自驱动施加器
US20050228313A1 (en) * 2003-12-04 2005-10-13 University Technologies International Inc. Fluid sampling, analysis and delivery system
CN1893992A (zh) * 2003-12-18 2007-01-10 诺沃挪第克公司 具有皮肤拉紧装置的喷嘴设备
US20070073220A1 (en) * 2004-10-06 2007-03-29 Philip Bunce Inoculation device
US8057842B2 (en) * 2004-11-18 2011-11-15 3M Innovative Properties Company Method of contact coating a microneedle array
US8267889B2 (en) 2004-11-18 2012-09-18 3M Innovative Properties Company Low-profile microneedle array applicator
CA2589733C (en) * 2004-12-07 2014-02-11 3M Innovative Properties Company Method of molding a microneedle
WO2007002523A2 (en) * 2005-06-24 2007-01-04 3M Innovative Properties Company Collapsible patch with microneedle array
AU2006261898B2 (en) * 2005-06-27 2011-11-03 3M Innovative Properties Company Microneedle array applicator device
US7658728B2 (en) * 2006-01-10 2010-02-09 Yuzhakov Vadim V Microneedle array, patch, and applicator for transdermal drug delivery
US9119945B2 (en) * 2006-04-20 2015-09-01 3M Innovative Properties Company Device for applying a microneedle array
WO2012061556A1 (en) 2010-11-03 2012-05-10 Flugen, Inc. Wearable drug delivery device having spring drive and sliding actuation mechanism

Also Published As

Publication number Publication date
MX2007005813A (es) 2007-07-18
CA2587505C (en) 2013-01-08
CN101060883A (zh) 2007-10-24
KR20130026511A (ko) 2013-03-13
US8267889B2 (en) 2012-09-18
KR20070102669A (ko) 2007-10-19
IL183204A (en) 2013-07-31
EP1833547A1 (en) 2007-09-19
AU2005306422A1 (en) 2006-05-26
JP2012183358A (ja) 2012-09-27
US8758298B2 (en) 2014-06-24
CN101060883B (zh) 2010-06-23
US20080114298A1 (en) 2008-05-15
JP2008520369A (ja) 2008-06-19
IL183204A0 (en) 2007-08-19
JP5587946B2 (ja) 2014-09-10
ZA200705102B (en) 2008-10-29
WO2006055795A1 (en) 2006-05-26
US20130006219A1 (en) 2013-01-03
CA2587505A1 (en) 2006-05-26

Similar Documents

Publication Publication Date Title
BRPI0517749A (pt) dispositivo de aplicação para aplicar um dispositivo de micro-agulha a uma superfìcie de pele, e, método para usar um dispositivo de aplicação
BRPI0820581A8 (pt) Dispositivo de interface com paciente, e, cânula nasal
AR044963A1 (es) Aparato y metodo para recubrir microproyecciones de perforacion de la piel
DE60111771D1 (de) Mikroklingeanordungsaufprallapplikator
ATE543441T1 (de) Nahtfreisetzung
BRPI0415629A (pt) aplicador auto-atuador para conjunto de microprojeções
BR0312671A (pt) Dispositivo de microagulhas, método para utilizar um dispositivo de microagulhas, e, método para aplicar um dispositivo de microagulhas
BRPI0416822A (pt) método e sistema de liberação de vacina transdérmica com ultra-som
BR112018005587A8 (pt) Métodos para aprimorar a aplicação tópica de um agente de benefício básico
ATE439085T1 (de) Expressionsvorrichtung mit geteilter spitze
ATE443505T1 (de) Massagevorrichtung
BRPI0519882A2 (pt) cabo de aparelho e aparelho para barbear
BRPI0518181A (pt) dispositivo e método de aplicação de fluido
BRPI0313214A2 (pt) dispositivo e procedimento para a medida da elasticidade de um órgão humano ou animal
BRPI0517501A (pt) dispositivo médico apropriado para uso na administração de um componente ativo na ou através da pele
BR0002192A (pt) Aplicador para aplicação de um produto e utilização de um aplicador
DE502007005362D1 (de) Biegeweiche vorrichtung zum einbringen einer medizinischen vorrichtung in den körper
BRPI0508678A (pt) emplastro para provisão de terapia a um indivìduo, método para provisão de terapia a um indivìduo e método de fabricação de um emplatro que provê terapia a um indivìduo
BR0212963A (pt) Microdispositivo e método de fornecer ou retirar uma substância através da pele de um animal
BR0202111A (pt) Dispositivo para a aplicação de um produto de bronzeamento artificial sobre a pele, kit e processo de fabricação de um tal dispositivo
BRPI0314854B8 (pt) cateter balão, processo para seu revestimento, e uso de uma solução.
BRPI0601026A (pt) dispositivo de acondicionamento e de aplicação
BRPI0602604A (pt) aparelho útil para posicionar um dispositivo em um endoscópio
EP2289574A3 (en) Medical devices and methods of making medical devices
ATE521056T1 (de) Simulator für das training von minimal-invasiven medizinischen operationen

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.