AR047229A1 - Administracion de conjugados polimericos de peptidos y proteinas terapeuticos por medio de microproyecciones revestidas - Google Patents
Administracion de conjugados polimericos de peptidos y proteinas terapeuticos por medio de microproyecciones revestidasInfo
- Publication number
- AR047229A1 AR047229A1 ARP040103915A ARP040103915A AR047229A1 AR 047229 A1 AR047229 A1 AR 047229A1 AR P040103915 A ARP040103915 A AR P040103915A AR P040103915 A ARP040103915 A AR P040103915A AR 047229 A1 AR047229 A1 AR 047229A1
- Authority
- AR
- Argentina
- Prior art keywords
- microprojections
- administration
- peptides
- covered
- therapeutic proteins
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/20—Surgical instruments, devices or methods, e.g. tourniquets for vaccinating or cleaning the skin previous to the vaccination
- A61B17/205—Vaccinating by means of needles or other puncturing devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
- A61B2017/00893—Material properties pharmaceutically effective
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0023—Drug applicators using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0046—Solid microneedles
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicinal Chemistry (AREA)
- Medical Informatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Un aparato para la administracion por vía transdérmica de un agente biologicamente activo a un paciente, que comprende una pieza con microproyecciones que cuenta con una pluralidad de microproyecciones que están adaptadas para perforar el estrato corneo del usuario de nicotina, donde la pieza con microproyecciones tiene un revestimiento biocompatible dispuesto sobre la misma que incluye un agente biologicamente activo seleccionado del grupo formado por conjugados de péptidos y proteínas. Método para administracion transdérmica.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US51539803P | 2003-10-28 | 2003-10-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR047229A1 true AR047229A1 (es) | 2006-01-11 |
Family
ID=34572834
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP040103915A AR047229A1 (es) | 2003-10-28 | 2004-10-27 | Administracion de conjugados polimericos de peptidos y proteinas terapeuticos por medio de microproyecciones revestidas |
Country Status (11)
Country | Link |
---|---|
US (1) | US20050106227A1 (es) |
EP (1) | EP1677687A4 (es) |
JP (1) | JP2007535337A (es) |
KR (1) | KR20070001886A (es) |
CN (1) | CN1897883A (es) |
AR (1) | AR047229A1 (es) |
AU (1) | AU2004287059A1 (es) |
BR (1) | BRPI0415967A (es) |
CA (1) | CA2543280A1 (es) |
TW (1) | TW200539907A (es) |
WO (1) | WO2005044985A2 (es) |
Families Citing this family (36)
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DK0914178T3 (da) * | 1996-06-18 | 2003-04-22 | Alza Corp | Anordning til forøgelse af transdermal afgivelse eller prøveudtagning af et middel |
BR0114628A (pt) * | 2000-10-13 | 2004-01-20 | Alza Corp | Membro de retenção em microprojeção para aplicador de impacto |
US7419481B2 (en) * | 2000-10-13 | 2008-09-02 | Alza Corporation | Apparatus and method for piercing skin with microprotrusions |
CZ20031037A3 (cs) * | 2000-10-13 | 2003-10-15 | Alza Corporation | Zařízení a způsob probodnutí kůže mikrovýčnělky |
JP4659336B2 (ja) * | 2000-10-26 | 2011-03-30 | アルザ・コーポレーシヨン | 被覆された微細突出物を有する経皮的薬剤配達装置 |
US6855372B2 (en) * | 2001-03-16 | 2005-02-15 | Alza Corporation | Method and apparatus for coating skin piercing microprojections |
US20020193729A1 (en) * | 2001-04-20 | 2002-12-19 | Cormier Michel J.N. | Microprojection array immunization patch and method |
US6908453B2 (en) * | 2002-01-15 | 2005-06-21 | 3M Innovative Properties Company | Microneedle devices and methods of manufacture |
US8961477B2 (en) * | 2003-08-25 | 2015-02-24 | 3M Innovative Properties Company | Delivery of immune response modifier compounds |
AU2004286232A1 (en) * | 2003-10-23 | 2005-05-12 | Alza Corporation | Compositions of stabilized DNA for coating microprojections |
EP1675539A4 (en) * | 2003-10-24 | 2007-09-12 | Alza Corp | METHOD AND SYSTEM FOR PRETREATMENT FOR IMPROVING TRANSDERMAL DRUG DELIVERY |
BRPI0415986A (pt) * | 2003-10-28 | 2007-01-23 | Alza Corp | método e aparelho para reduzir a incidência do uso de tabaco |
KR20060099523A (ko) | 2003-10-31 | 2006-09-19 | 알자 코포레이션 | 미세 돌출부 어레이를 위한 자가 작동 어플리케이터 |
MXPA06005677A (es) * | 2003-11-21 | 2006-12-14 | Johnson & Johnson | Metodo y sistema de suministro transdermico de vacuna asistido por ultrasonido. |
WO2005103303A2 (en) * | 2004-04-13 | 2005-11-03 | Alza Corporation | Apparatus and method for transdermal delivery of multiple vaccines |
ES2568259T3 (es) * | 2004-05-13 | 2016-04-28 | Alza Corporation | Aparato y método para la administración transdérmica de agentes de hormona paratiroidea |
MX2007002795A (es) * | 2004-09-08 | 2008-03-05 | Johnson & Johnson | Arreglo de microproyeccion con adhesion y adaptacion a la piel, mejoradas. |
KR101246015B1 (ko) | 2004-11-18 | 2013-03-20 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | 마이크로니들 어레이를 접촉 코팅하는 방법 |
KR101224257B1 (ko) * | 2004-11-18 | 2013-01-18 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | 마이크로니들 어레이를 코팅하기 위한 마스킹 방법 |
US8057842B2 (en) | 2004-11-18 | 2011-11-15 | 3M Innovative Properties Company | Method of contact coating a microneedle array |
JP4913030B2 (ja) * | 2005-01-31 | 2012-04-11 | 株式会社バイオセレンタック | 経皮吸収製剤、経皮吸収製剤保持シート、及び経皮吸収製剤保持用具 |
EP1904158B1 (en) * | 2005-06-24 | 2013-07-24 | 3M Innovative Properties Company | Collapsible patch with microneedle array |
CN101267896A (zh) * | 2005-09-12 | 2008-09-17 | 阿尔扎公司 | 可涂覆的透皮给药微突起组合件 |
WO2007061964A1 (en) * | 2005-11-18 | 2007-05-31 | 3M Innovative Properties Company | Methods for coating microneedles |
US20070293816A1 (en) * | 2006-04-25 | 2007-12-20 | Alza Corporation | Microprojection Array Application with Grouped Microprojections for High Drug Loading |
US20070299388A1 (en) * | 2006-04-25 | 2007-12-27 | Alza Corporation | Microprojection array application with multilayered microprojection member for high drug loading |
AU2011258288B2 (en) | 2010-05-28 | 2015-02-12 | Kindeva Drug Delivery L.P. | Aqueous formulations for coating microneedle arrays |
AU2012256403B2 (en) | 2011-03-17 | 2016-10-20 | Corning Incorporated | Synthetic coating for cell culture |
JP6033280B2 (ja) * | 2011-04-22 | 2016-11-30 | ラジウス ヘルス,インコーポレイテッド | PTH、PTHrP、および関連ペプチドの薬剤送達方法 |
WO2012150475A1 (en) * | 2011-05-05 | 2012-11-08 | Corning Incorporated | Synthetic composition and coating for cell culture. |
JP5870551B2 (ja) * | 2011-08-26 | 2016-03-01 | 大日本印刷株式会社 | マイクロニードルデバイスの製造方法 |
KR101724655B1 (ko) * | 2014-06-02 | 2017-04-13 | 주식회사 아모라이프사이언스 | 마이크로 니들 패치 및 그의 제조 방법 |
AU2016256470B2 (en) | 2015-04-29 | 2020-10-15 | Radius Pharmaceuticals, Inc. | Methods of treating cancer |
CN105833424A (zh) * | 2016-03-21 | 2016-08-10 | 南通纺织丝绸产业技术研究院 | 一种丝素蛋白微针贴及其制备方法 |
LT3565542T (lt) | 2017-01-05 | 2024-07-10 | Radius Pharmaceuticals, Inc. | Polimorfinės rad1901-2hcl formos |
CN112423844B (zh) | 2018-07-04 | 2024-08-13 | 雷迪厄斯制药公司 | Rad1901-2hcl的多晶型形式 |
Family Cites Families (33)
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US3123212A (en) * | 1964-03-03 | Multiple disposable intracutaneous injector package | ||
US2619962A (en) * | 1948-02-19 | 1952-12-02 | Res Foundation | Vaccination appliance |
US2893392A (en) * | 1958-01-08 | 1959-07-07 | American Cyanamid Co | Article of manufacture for intracutaneous injections |
US3072122A (en) * | 1959-01-15 | 1963-01-08 | Rosenthal Sol Roy | Package for transcutaneous injection |
US3136314A (en) * | 1960-08-01 | 1964-06-09 | Kravitz Harvey | Vaccinating devices |
US3221739A (en) * | 1962-03-26 | 1965-12-07 | Rosenthal Sol Roy | Injection device |
US3221740A (en) * | 1962-08-31 | 1965-12-07 | Rosenthal Sol Roy | Injection device |
US3964482A (en) * | 1971-05-17 | 1976-06-22 | Alza Corporation | Drug delivery device |
US3678150A (en) * | 1971-07-27 | 1972-07-18 | American Cyanamid Co | Process for improving the stability of ppd, qt and histoplasmin on tine applicators |
BE795384A (fr) * | 1972-02-14 | 1973-08-13 | Ici Ltd | Pansements |
US4179337A (en) * | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
OA05448A (fr) * | 1975-10-16 | 1981-03-31 | Manufrance Manufacture Francai | Dispositif vaccinateur multipénétrant. |
FR2474856A1 (fr) * | 1980-01-31 | 1981-08-07 | Merieux Inst | Dispositif scarificateur |
SE8501990D0 (sv) * | 1985-04-24 | 1985-04-24 | Pharmacia Ab | Beleggningsforfarande |
US5080646A (en) * | 1988-10-03 | 1992-01-14 | Alza Corporation | Membrane for electrotransport transdermal drug delivery |
US5147296A (en) * | 1988-10-03 | 1992-09-15 | Alza Corporation | Membrane for electrotransport transdermal drug delivery |
US5169382A (en) * | 1988-10-03 | 1992-12-08 | Alza Corporation | Membrane for electrotransport transdermal drug delivery |
EP0429842B1 (en) * | 1989-10-27 | 1996-08-28 | Korea Research Institute Of Chemical Technology | Device for the transdermal administration of protein or peptide drug |
US5487726A (en) * | 1994-06-16 | 1996-01-30 | Ryder International Corporation | Vaccine applicator system |
AU5740496A (en) * | 1995-05-22 | 1996-12-11 | General Hospital Corporation, The | Micromechanical device and method for enhancing delivery of compounds through the skin |
US5741554A (en) * | 1996-07-26 | 1998-04-21 | Bio Dot, Inc. | Method of dispensing a liquid reagent |
US5916524A (en) * | 1997-07-23 | 1999-06-29 | Bio-Dot, Inc. | Dispensing apparatus having improved dynamic range |
US5738728A (en) * | 1996-07-26 | 1998-04-14 | Bio Dot, Inc. | Precision metered aerosol dispensing apparatus |
US5743960A (en) * | 1996-07-26 | 1998-04-28 | Bio-Dot, Inc. | Precision metered solenoid valve dispenser |
AU739616B2 (en) * | 1997-12-11 | 2001-10-18 | Alza Corporation | Device for enhancing transdermal agent flux |
ES2244106T3 (es) * | 1997-12-11 | 2005-12-01 | Alza Corporation | Dispositivo para mejorar el flujo transdermico de agentes. |
US6091975A (en) * | 1998-04-01 | 2000-07-18 | Alza Corporation | Minimally invasive detecting device |
US20020095134A1 (en) * | 1999-10-14 | 2002-07-18 | Pettis Ronald J. | Method for altering drug pharmacokinetics based on medical delivery platform |
US6537242B1 (en) * | 2000-06-06 | 2003-03-25 | Becton, Dickinson And Company | Method and apparatus for enhancing penetration of a member for the intradermal sampling or administration of a substance |
BR0114628A (pt) * | 2000-10-13 | 2004-01-20 | Alza Corp | Membro de retenção em microprojeção para aplicador de impacto |
CZ20031037A3 (cs) * | 2000-10-13 | 2003-10-15 | Alza Corporation | Zařízení a způsob probodnutí kůže mikrovýčnělky |
US6573237B2 (en) * | 2001-03-16 | 2003-06-03 | Eli Lilly And Company | Protein formulations |
US6855372B2 (en) * | 2001-03-16 | 2005-02-15 | Alza Corporation | Method and apparatus for coating skin piercing microprojections |
-
2004
- 2004-10-21 CA CA002543280A patent/CA2543280A1/en not_active Abandoned
- 2004-10-21 AU AU2004287059A patent/AU2004287059A1/en not_active Abandoned
- 2004-10-21 KR KR1020067010339A patent/KR20070001886A/ko not_active Application Discontinuation
- 2004-10-21 US US10/972,231 patent/US20050106227A1/en not_active Abandoned
- 2004-10-21 EP EP04795996A patent/EP1677687A4/en not_active Withdrawn
- 2004-10-21 BR BRPI0415967-5A patent/BRPI0415967A/pt not_active IP Right Cessation
- 2004-10-21 CN CNA2004800390717A patent/CN1897883A/zh active Pending
- 2004-10-21 WO PCT/US2004/034925 patent/WO2005044985A2/en active Application Filing
- 2004-10-21 JP JP2006538113A patent/JP2007535337A/ja not_active Withdrawn
- 2004-10-27 AR ARP040103915A patent/AR047229A1/es not_active Application Discontinuation
- 2004-10-28 TW TW093132840A patent/TW200539907A/zh unknown
Also Published As
Publication number | Publication date |
---|---|
BRPI0415967A (pt) | 2007-01-23 |
AU2004287059A1 (en) | 2005-05-19 |
CA2543280A1 (en) | 2005-05-19 |
US20050106227A1 (en) | 2005-05-19 |
WO2005044985A3 (en) | 2005-10-20 |
KR20070001886A (ko) | 2007-01-04 |
WO2005044985A2 (en) | 2005-05-19 |
EP1677687A2 (en) | 2006-07-12 |
CN1897883A (zh) | 2007-01-17 |
TW200539907A (en) | 2005-12-16 |
JP2007535337A (ja) | 2007-12-06 |
EP1677687A4 (en) | 2008-09-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |