AR043239A1 - Composicion farmaceutica para la liberacion controlada de sustancias activas y metodos para su fabricacion - Google Patents

Composicion farmaceutica para la liberacion controlada de sustancias activas y metodos para su fabricacion

Info

Publication number
AR043239A1
AR043239A1 ARP040100527A ARP040100527A AR043239A1 AR 043239 A1 AR043239 A1 AR 043239A1 AR P040100527 A ARP040100527 A AR P040100527A AR P040100527 A ARP040100527 A AR P040100527A AR 043239 A1 AR043239 A1 AR 043239A1
Authority
AR
Argentina
Prior art keywords
pharmaceutical composition
controlled release
polyethylene oxide
manufacturing
controlling agent
Prior art date
Application number
ARP040100527A
Other languages
English (en)
Inventor
Akio Sugihara
Kazuhiro Sako
Toyohiro Sawada
Original Assignee
Yamanouchi Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharma Co Ltd filed Critical Yamanouchi Pharma Co Ltd
Publication of AR043239A1 publication Critical patent/AR043239A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Producto dimensionado, que contiene una droga, óxido de polietileno con un peso molecular de 2.000.000 o más alto, y un agente específico controlador de tamano para el óxido de polietileno (sustancia con la plasticidad y fuerza de ligado apropiado) y donde al menos el agente específico controlador de tamano mencionado está dispersado uniformemente en el óxido de polietileno mencionado, una composición farmacéutica de liberación controlada que contiene este producto dimensionado, y un método para fabricar una composición farmacéutica de liberación controlada que contiene este producto dimensionado. Una composición farmacéutica de liberación controlada con buena uniformidad de contenido puede prepararse usando partículas de polvo de óxido de polietileno con propiedades de polvo apropiadas para el tableteado, que se obtiene por la dispersión uniforme del agente específico controlador de tamano para el óxido de polietileno.
ARP040100527A 2003-03-06 2004-02-20 Composicion farmaceutica para la liberacion controlada de sustancias activas y metodos para su fabricacion AR043239A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US45304603P 2003-03-06 2003-03-06

Publications (1)

Publication Number Publication Date
AR043239A1 true AR043239A1 (es) 2005-07-20

Family

ID=32772091

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP040100527A AR043239A1 (es) 2003-03-06 2004-02-20 Composicion farmaceutica para la liberacion controlada de sustancias activas y metodos para su fabricacion

Country Status (20)

Country Link
US (2) US7442387B2 (es)
EP (1) EP1523994B1 (es)
JP (2) JP3755532B2 (es)
KR (1) KR101061394B1 (es)
CN (1) CN1691965B (es)
AR (1) AR043239A1 (es)
AU (1) AU2003292756B2 (es)
BR (1) BR0311908A (es)
CA (1) CA2490299C (es)
CZ (1) CZ14386U1 (es)
DE (1) DE202004003404U1 (es)
ES (1) ES2432354T3 (es)
GB (1) GB2402063B (es)
MX (1) MXPA04012974A (es)
PL (1) PL209908B1 (es)
PT (1) PT1523994E (es)
RU (1) RU2291711C2 (es)
TW (1) TWI307632B (es)
WO (1) WO2004078212A1 (es)
ZA (1) ZA200410386B (es)

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ES2432354T3 (es) 2013-12-02
RU2291711C2 (ru) 2007-01-20
AU2003292756A1 (en) 2004-09-28
PT1523994E (pt) 2013-12-19
PL209908B1 (pl) 2011-11-30
ZA200410386B (en) 2006-06-28
AU2003292756B2 (en) 2008-07-31
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GB2402063A (en) 2004-12-01
CA2490299C (en) 2008-08-26
US20090035372A1 (en) 2009-02-05
EP1523994A1 (en) 2005-04-20
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EP1523994A4 (en) 2011-03-30
CZ14386U1 (cs) 2004-06-01
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TWI307632B (en) 2009-03-21
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