DE69322764T2 - Herstellungsmethode für feines granulat - Google Patents

Herstellungsmethode für feines granulat

Info

Publication number
DE69322764T2
DE69322764T2 DE69322764T DE69322764T DE69322764T2 DE 69322764 T2 DE69322764 T2 DE 69322764T2 DE 69322764 T DE69322764 T DE 69322764T DE 69322764 T DE69322764 T DE 69322764T DE 69322764 T2 DE69322764 T2 DE 69322764T2
Authority
DE
Germany
Prior art keywords
manufacturing
fine granules
granules
fine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69322764T
Other languages
English (en)
Other versions
DE69322764D1 (de
Inventor
Yoshiaki Yano
Tamiji Fujimoto
Takayoshi Hidaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Activbiotics Inc
Original Assignee
Kanegafuchi Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kanegafuchi Chemical Industry Co Ltd filed Critical Kanegafuchi Chemical Industry Co Ltd
Publication of DE69322764D1 publication Critical patent/DE69322764D1/de
Application granted granted Critical
Publication of DE69322764T2 publication Critical patent/DE69322764T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/16—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by suspending the powder material in a gas, e.g. in fluidised beds or as a falling curtain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/10—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic in stationary drums or troughs, provided with kneading or mixing appliances
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/12—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic in rotating drums
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Fertilizers (AREA)
  • Glanulating (AREA)
DE69322764T 1992-10-09 1993-10-06 Herstellungsmethode für feines granulat Expired - Lifetime DE69322764T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP29790592 1992-10-09
PCT/JP1993/001442 WO1994008709A1 (en) 1992-10-09 1993-10-06 Production method for fine granulate

Publications (2)

Publication Number Publication Date
DE69322764D1 DE69322764D1 (de) 1999-02-04
DE69322764T2 true DE69322764T2 (de) 1999-05-06

Family

ID=17852618

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69322764T Expired - Lifetime DE69322764T2 (de) 1992-10-09 1993-10-06 Herstellungsmethode für feines granulat

Country Status (9)

Country Link
US (1) US5547683A (de)
EP (1) EP0616841B1 (de)
JP (1) JP3492688B2 (de)
KR (1) KR100294525B1 (de)
CN (1) CN1089234C (de)
CA (1) CA2124568C (de)
DE (1) DE69322764T2 (de)
ES (1) ES2124794T3 (de)
WO (1) WO1994008709A1 (de)

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EP2266560A1 (de) * 1996-03-26 2010-12-29 Eli Lilly & Company Benzothiophene und denen enthaltende Zusammensetzungen
EP1147770A1 (de) * 1996-07-01 2001-10-24 Pfizer Inc. Virginiamycinmischung
ES2129010B1 (es) * 1997-01-02 2000-01-16 Gold Oscar Composicion de accion prolongada en granulos que contienen 4-nitro-2- fenoximetansulfonanilida y su procedimiento de preparacion.
US6045829A (en) * 1997-02-13 2000-04-04 Elan Pharma International Limited Nanocrystalline formulations of human immunodeficiency virus (HIV) protease inhibitors using cellulosic surface stabilizers
FR2760190B1 (fr) * 1997-02-28 1999-04-09 Adir Composition pharmaceutique pour la liberation programmee de dexfenfluramine
US6013280A (en) * 1997-10-07 2000-01-11 Fuisz Technologies Ltd. Immediate release dosage forms containing microspheres
JP2007246539A (ja) * 1997-10-20 2007-09-27 Dainippon Sumitomo Pharma Co Ltd 速溶性医薬組成物
JP2000128774A (ja) * 1998-10-26 2000-05-09 Tanabe Seiyaku Co Ltd 薬物を含有する球形微粒子の製法
FR2791905B1 (fr) * 1999-04-09 2001-09-14 Toulouse Inst Nat Polytech Procede d'enrobage et de pelliculage de poudres fines dans un enrobeur a lit fluidise
US6417227B1 (en) 1999-04-28 2002-07-09 Cg And Associates Methods of delivery of cetyl myristoleate
DE10005280A1 (de) * 2000-02-07 2001-08-09 Bayer Ag Partikuläre Zusammensetzung, Verfahren zu ihrer Herstellung und deren Verwendung
EP1311243A2 (de) * 2000-08-25 2003-05-21 MERCK PATENT GmbH Verfahren zur herstellung und verwendung von pulverförmigem mannitol sowie mannitol enthaltenden zusammensetzungen
JP2004532644A (ja) * 2001-06-19 2004-10-28 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー 食品粒子の乾燥被覆方法または凍結液体粒子の封入方法
JP2003001091A (ja) * 2001-06-26 2003-01-07 Pauretsuku:Kk 流動層造粒・コーティング方法
US7122525B2 (en) * 2001-11-21 2006-10-17 Activbiotics, Inc. Targeted therapeutics and uses thereof
AU2002364162A1 (en) * 2001-12-13 2003-06-30 Activbiotics, Inc. Sulfhydryl rifamycins and uses thereof
US20040131730A1 (en) * 2002-06-19 2004-07-08 Dalziel Sean M. Process for dry coating a food particle or encapsulating a frozen liquid particle
DE60330161D1 (de) * 2002-08-29 2009-12-31 Activbiotics Pharma Llc Rifalazil zur behandlung von infektionen mit clostridium difficile
US9060941B2 (en) * 2002-09-20 2015-06-23 Actavis, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
TW200418485A (en) * 2002-09-23 2004-10-01 Activbiotics Inc Rifalazil compositions and therapeutic regimens
US8980870B2 (en) * 2002-09-24 2015-03-17 Boehringer Ingelheim International Gmbh Solid telmisartan pharmaceutical formulations
MXPA05007883A (es) * 2003-01-29 2005-09-21 Takeda Pharmaceutical Proceso para producir una preparacion recubierta.
US7442387B2 (en) 2003-03-06 2008-10-28 Astellas Pharma Inc. Pharmaceutical composition for controlled release of active substances and manufacturing method thereof
US20040253308A1 (en) * 2003-04-29 2004-12-16 Barr Laboratories, Inc. Surface-treated modafinil particles
CA2531486C (en) * 2003-07-11 2012-10-02 Antonio A. Albano Saquinavir mesylate oral dosage form
FR2857591B1 (fr) * 2003-07-17 2007-11-02 Ethypharm Sa Particules comprenant un principe actif sous forme de co-precipite
US7342011B2 (en) * 2003-08-22 2008-03-11 Activbiotics, Inc. Rifamycin analogs and uses thereof
US7820652B2 (en) * 2003-09-24 2010-10-26 Activbiotics Pharma, Llc Regimen for the administration of rifamycin-class antibiotics
EP1675548A4 (de) * 2003-09-25 2008-08-13 Activbiotics Inc Rifalazil-formulierungen
WO2005058231A2 (en) * 2003-12-10 2005-06-30 Activbiotics, Inc. Rifamycin analogs and uses thereof
AU2004308399A1 (en) * 2003-12-23 2005-07-14 Activbiotics, Inc. Rifamycin analogs and uses thereof
EP1698349A4 (de) * 2003-12-25 2009-12-16 Takeda Pharmaceutical Verfahren zur verbesserung der eignung für die granulation
EP1642922B2 (de) * 2004-09-30 2015-02-25 Shin-Etsu Chemical Co., Ltd. Kaltwasserlösliche Polymerpartikel und Verfahren zur Herstellung
CA2642761A1 (en) * 2006-02-23 2007-08-30 Iomedix Sleep International Srl Compositions and methods for the induction and maintenance of quality sleep
CN101437518A (zh) * 2006-04-06 2009-05-20 活跃生物药物学有限公司 药物组合物及其应用
CA2649619C (en) * 2006-04-17 2012-08-28 Meiji Seika Kaisha, Ltd. Whey protein-containing granules and method of producing the same
JP4065902B2 (ja) * 2006-04-28 2008-03-26 ライオン株式会社 造粒粒子、錠剤、及び造粒粒子の製造方法
JP2007314529A (ja) * 2006-04-28 2007-12-06 Lion Corp 造粒粒子、錠剤、及び造粒粒子の製造方法
JP5361188B2 (ja) * 2006-08-10 2013-12-04 武田薬品工業株式会社 医薬組成物
US20110117154A1 (en) * 2008-07-07 2011-05-19 Activbiotics Pharma, Llc Use of rifalazil to treat colonic disorders
GB0814953D0 (en) * 2008-08-18 2008-09-24 Unilever Plc Improvements relating to nanodisperse compositions
AU2010221167B2 (en) * 2009-03-06 2014-04-03 Xenoport, Inc. Oral dosage forms having a high loading of a gabapentin prodrug
MX2012000827A (es) * 2009-07-17 2012-03-26 Carefusion 2200 Inc Particulas que incorporan agentes antimicrobianos.
WO2011125500A1 (ja) * 2010-03-31 2011-10-13 エスエス製薬株式会社 難水溶性薬物含有微粒子造粒物の製造法
WO2012103116A1 (en) * 2011-01-24 2012-08-02 Activbiotics Pharma, Llc Pulmonary administration of rifalazil and analogs thereof
CN105848644A (zh) * 2013-12-23 2016-08-10 埃斯特韦实验室有限公司 经口药物组合物
CN108261396B (zh) * 2016-12-30 2021-12-24 北京化工大学 一种制粒方法
JP7389620B2 (ja) * 2019-11-11 2023-11-30 花王株式会社 造粒物の製造方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS563326B2 (de) * 1972-09-11 1981-01-24
JPS5432176A (en) * 1977-08-15 1979-03-09 Sanyo Kokusaku Pulp Co Ltd Granulating and drying method by fluidization
JPS55129220A (en) * 1980-02-08 1980-10-06 Yamanouchi Pharmaceut Co Ltd Composition for solid preparation containing hardly soluble medicinal component having rapid action and high bioavailability
GB2072037A (en) * 1980-03-20 1981-09-30 Standard Telephones Cables Ltd Fluidising fine powder
JPS6168133A (ja) * 1984-09-08 1986-04-08 Shinjiro Tsuji 造粒方法
JPS63240934A (ja) * 1987-03-28 1988-10-06 Taisho Pharmaceut Co Ltd 薬物の造粒法
JPH06128147A (ja) * 1992-10-20 1994-05-10 Masayasu Sugihara 水難溶性薬品の溶解性改善方法およびそれにより得られた薬品組成物

Also Published As

Publication number Publication date
EP0616841A1 (de) 1994-09-28
KR100294525B1 (ko) 2001-09-17
EP0616841A4 (de) 1996-04-03
CN1089234C (zh) 2002-08-21
CN1091628A (zh) 1994-09-07
EP0616841B1 (de) 1998-12-23
ES2124794T3 (es) 1999-02-16
JP3492688B2 (ja) 2004-02-03
US5547683A (en) 1996-08-20
DE69322764D1 (de) 1999-02-04
WO1994008709A1 (en) 1994-04-28
CA2124568C (en) 2003-11-11
CA2124568A1 (en) 1994-04-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ACTIVBIOTICS,INC., LEXINGTON, MASS., US