AR035327A1 - Agonistas no peptidicos de la vasopresina, selectivos para los receptores del subtipo v2; uso de dichos compuestos en la preparacion de composiciones farmaceuticas utilizables en el tratamiento de enfermedades del hombre, caracterizadas por poliuria; dichas composiciones y metodos para el tratamient - Google Patents

Agonistas no peptidicos de la vasopresina, selectivos para los receptores del subtipo v2; uso de dichos compuestos en la preparacion de composiciones farmaceuticas utilizables en el tratamiento de enfermedades del hombre, caracterizadas por poliuria; dichas composiciones y metodos para el tratamient

Info

Publication number
AR035327A1
AR035327A1 ARP010100035A ARP010100035A AR035327A1 AR 035327 A1 AR035327 A1 AR 035327A1 AR P010100035 A ARP010100035 A AR P010100035A AR P010100035 A ARP010100035 A AR P010100035A AR 035327 A1 AR035327 A1 AR 035327A1
Authority
AR
Argentina
Prior art keywords
treatment
independently selected
compounds
pharmaceutical compositions
vasopresine
Prior art date
Application number
ARP010100035A
Other languages
English (en)
Spanish (es)
Original Assignee
Ferring Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferring Bv filed Critical Ferring Bv
Publication of AR035327A1 publication Critical patent/AR035327A1/es

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/10Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12Antidiuretics, e.g. drugs for diabetes insipidus
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ARP010100035A 2000-01-05 2001-01-04 Agonistas no peptidicos de la vasopresina, selectivos para los receptores del subtipo v2; uso de dichos compuestos en la preparacion de composiciones farmaceuticas utilizables en el tratamiento de enfermedades del hombre, caracterizadas por poliuria; dichas composiciones y metodos para el tratamient AR035327A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0000079.4A GB0000079D0 (en) 2000-01-05 2000-01-05 Novel antidiuretic agents

Publications (1)

Publication Number Publication Date
AR035327A1 true AR035327A1 (es) 2004-05-12

Family

ID=9883168

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP010100035A AR035327A1 (es) 2000-01-05 2001-01-04 Agonistas no peptidicos de la vasopresina, selectivos para los receptores del subtipo v2; uso de dichos compuestos en la preparacion de composiciones farmaceuticas utilizables en el tratamiento de enfermedades del hombre, caracterizadas por poliuria; dichas composiciones y metodos para el tratamient

Country Status (34)

Country Link
US (3) US7074781B2 (https=)
EP (1) EP1248784B1 (https=)
JP (2) JP3869723B2 (https=)
KR (1) KR100605466B1 (https=)
CN (1) CN1183129C (https=)
AR (1) AR035327A1 (https=)
AT (1) ATE366730T1 (https=)
AU (1) AU777538B2 (https=)
BR (1) BR0107414B1 (https=)
CA (1) CA2396277C (https=)
CY (1) CY1108034T1 (https=)
CZ (1) CZ303444B6 (https=)
DE (1) DE60129298T2 (https=)
DK (1) DK1248784T3 (https=)
EE (1) EE200200367A (https=)
ES (1) ES2288923T3 (https=)
GB (1) GB0000079D0 (https=)
HK (1) HK1046910B (https=)
HR (1) HRP20020481B1 (https=)
HU (1) HU229937B1 (https=)
IL (1) IL149528A0 (https=)
MX (1) MXPA02006546A (https=)
MY (1) MY140467A (https=)
NO (1) NO322571B1 (https=)
NZ (1) NZ518803A (https=)
PL (1) PL211341B1 (https=)
PT (1) PT1248784E (https=)
RU (1) RU2259367C2 (https=)
SI (1) SI1248784T1 (https=)
SK (1) SK287005B6 (https=)
UA (1) UA73152C2 (https=)
UY (1) UY26521A1 (https=)
WO (1) WO2001049682A1 (https=)
ZA (1) ZA200205180B (https=)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5803659A (en) 1995-12-08 1998-09-08 Chattey; Nigel Modular caissons for use in constructing, expanding and modernizing ports and harbors.
US7138393B2 (en) 1998-07-24 2006-11-21 Wyeth Biologically active vasopressin agonist metabolites
GB0000079D0 (en) * 2000-01-05 2000-02-23 Ferring Bv Novel antidiuretic agents
ATE329899T1 (de) * 2000-03-27 2006-07-15 Applied Research Systems Pharmazeutisch wirksame pyrrolidin-derivate als bax-inhibitoren
AU2001256209B2 (en) * 2000-03-27 2006-02-16 Merck Serono Sa Pharmaceutically active pyrrolidine derivatives
GB0015601D0 (en) * 2000-06-26 2000-08-16 Ferring Bv Novel antidiuretic agents
GB0115515D0 (en) * 2001-06-25 2001-08-15 Ferring Bv Oxytocin agonisys
GB0210397D0 (en) * 2002-05-07 2002-06-12 Ferring Bv Pharmaceutical formulations
EP1619185B1 (en) 2003-04-28 2011-06-15 Astellas Pharma Inc. 4,4-difluoro-1,2,3,4-tetrahydro-5h-1-benzazepine derivative or salt thereof
DK1530967T3 (da) * 2003-11-13 2006-07-03 Ferring Bv Blisterpakning og dertil hörende fast dosisform
WO2006054560A1 (ja) * 2004-11-17 2006-05-26 Kissei Pharmaceutical Co., Ltd. 芳香族アミド誘導体、それを含有する医薬組成物およびそれらの医薬用途
WO2006104008A1 (ja) * 2005-03-25 2006-10-05 Kissei Pharmaceutical Co., Ltd. ウレア誘導体、それを含有する医薬組成物およびそれらの医薬用途
WO2007052517A1 (ja) * 2005-10-31 2007-05-10 Sumitomo Chemical Company, Limited ヒドロキシ-2-ピロリジンカルボキシアミド化合物の製法
TW200820976A (en) * 2006-09-25 2008-05-16 Kissei Pharmaceutical 1,4-benzodiazepine derivative, pharmaceutical composition comprising the same, and use of the same for medical purposes
US9096546B2 (en) * 2007-05-10 2015-08-04 Albany Molecular Research, Inc. Aryl- and heteroaryl-substituted tetrahydrobenzo-1,4-diazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
JP5451613B2 (ja) 2007-08-06 2014-03-26 アラーガン、インコーポレイテッド デスモプレシン薬物送達のための方法及びデバイス
US11963995B2 (en) 2008-05-21 2024-04-23 Ferring B.V. Methods comprising desmopressin
NO3085381T3 (https=) * 2008-05-21 2018-09-15
US20100286045A1 (en) 2008-05-21 2010-11-11 Bjarke Mirner Klein Methods comprising desmopressin
GB201005623D0 (en) * 2010-04-01 2010-05-19 Vantia Ltd New polymorph
GB201105537D0 (en) * 2011-03-31 2011-05-18 Vantia Ltd New process
WO2020154581A1 (en) 2019-01-24 2020-07-30 Assia Chemical Industries Ltd Solid state forms of fedovapagon-salicyclic acid co-crystal

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3960886A (en) 1968-07-03 1976-06-01 Sterling Drug Inc. Substituted N-arylanilines
CH599752A5 (https=) 1973-04-18 1978-05-31 Ciba Geigy Ag
CA1047490A (en) 1973-04-18 1979-01-30 Friedrich Karrer Ethers
DE2355454A1 (de) 1973-11-07 1976-10-07 Paul Geisslinger Lochmaschine
CA1265798A (en) 1984-12-10 1990-02-13 Motoo Mutsukado 3(2h)pyridazinone, process for its preparation and anti-allergic agent containing it
DK0450097T3 (da) 1989-10-20 1996-05-20 Otsuka Pharma Co Ltd Benzoheterocykliske forbindelser
US5753677A (en) 1989-10-20 1998-05-19 Otsuka Pharmaceutical Co., Ltd. Benzoheterocyclic compounds
TW198715B (https=) * 1991-04-19 1993-01-21 Dtsuka Seiyaku Kk
JPH05320135A (ja) 1992-05-19 1993-12-03 Yamanouchi Pharmaceut Co Ltd テトラヒドロベンズアゼピン誘導体
WO1994004525A1 (en) 1992-08-20 1994-03-03 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds as oxytocin and vasopressin antagonists
TW270927B (https=) * 1992-10-16 1996-02-21 Otsuka Pharma Co Ltd
WO1994012476A1 (fr) * 1992-11-25 1994-06-09 Yamanouchi Pharmaceutical Co., Ltd. Derive de benzanilide
WO1994020473A1 (fr) * 1993-03-11 1994-09-15 Yamanouchi Pharmaceutical Co., Ltd. Compose avec action antagoniste de la vasopressine
GB9307527D0 (en) 1993-04-13 1993-06-02 Fujisawa Pharmaceutical Co New venzamide derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same
US5760031A (en) 1993-07-29 1998-06-02 American Cyanamid Company Tricyclic benzazepine vasopressin antagonists
US5968930A (en) 1993-07-29 1999-10-19 American Cyanamid Company Tricyclic diazepine vasopressin antagonists and oxytocin antagonists
US5516774A (en) 1993-07-29 1996-05-14 American Cyanamid Company Tricyclic diazepine vasopressin antagonists and oxytocin antagonists
US5843952A (en) 1993-07-29 1998-12-01 American Cyanamid Company Tricyclic benzazepine vasopressin antagonists
US6403577B1 (en) * 1993-11-17 2002-06-11 Eli Lilly And Company Hexamethyleneiminyl tachykinin receptor antagonists
FI1215U1 (fi) * 1993-12-03 1994-02-21 Valmet Paper Machinery Inc Anlaeggning i samband med styrningen av en vira
FR2716194B1 (fr) * 1994-02-14 1996-05-31 Sanofi Elf Dérivés de 3-acylamino-5-phényl-1,4-benzodiazépin-2-one polysubstitués, leur procédé de préparation et les compositions pharmaceutiques les contenant.
DE69514191T2 (de) * 1994-05-06 2000-08-17 Koninklijke Philips Electronics N.V., Eindhoven Mikrowellenübertragungssystem
ES2199251T3 (es) 1994-06-15 2004-02-16 Otsuka Pharmaceutical Company, Limited Derivados benzoheterociclicos utilizables como moduladores de vasopresina o de oxitocina.
JP2926335B2 (ja) 1997-06-13 1999-07-28 大塚製薬株式会社 医薬組成物
DE69826487T2 (de) * 1997-07-30 2005-12-01 Wyeth Trizyclische vasopressin-agonisten
BR9811559A (pt) * 1997-07-30 2000-09-12 American Home Prod Agonistas tricìclicos de vasopressina
JP2002527438A (ja) 1998-10-09 2002-08-27 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 4,5−ジヒドロ−イソオキサゾール誘導体及びそれらの製薬学的使用
GB2355454A (en) 1999-10-20 2001-04-25 Ferring Bv Antidiuretic agents
GB0000079D0 (en) * 2000-01-05 2000-02-23 Ferring Bv Novel antidiuretic agents
GB0015601D0 (en) 2000-06-26 2000-08-16 Ferring Bv Novel antidiuretic agents
DE10033337A1 (de) 2000-07-08 2002-01-17 Boehringer Ingelheim Pharma Biphenylcarbonsäureamide, ihre Herstellung und ihre Verwendung als Arzneimittel
GB0120051D0 (en) 2001-08-16 2001-10-10 Ferring Bv Oxytocin agonists
GB0224557D0 (en) 2002-10-22 2002-11-27 Glaxo Group Ltd Novel compounds
EP1449844A1 (en) 2003-02-14 2004-08-25 Ferring B.V. benzamide derivatives as oxytocin agonists and vasopressin antagonists
EP1627876A1 (en) 2004-08-20 2006-02-22 Ferring B.V. Heterocyclic condensed compounds useful as antidiuretic agents
US7341963B2 (en) * 2005-05-17 2008-03-11 Milliken & Company Non-woven material with barrier skin

Also Published As

Publication number Publication date
HRP20020481B1 (hr) 2009-03-31
US20080261951A1 (en) 2008-10-23
EP1248784B1 (en) 2007-07-11
JP2006137767A (ja) 2006-06-01
HUP0203917A2 (hu) 2003-03-28
CN1183129C (zh) 2005-01-05
BR0107414A (pt) 2002-10-08
HU229937B1 (hu) 2015-01-28
AU2384601A (en) 2001-07-16
ES2288923T3 (es) 2008-02-01
AU777538B2 (en) 2004-10-21
CY1108034T1 (el) 2013-09-04
NZ518803A (en) 2003-03-28
SK9112002A3 (en) 2003-01-09
CZ303444B6 (cs) 2012-09-19
CN1392875A (zh) 2003-01-22
JP3869723B2 (ja) 2007-01-17
RU2259367C2 (ru) 2005-08-27
US20030087892A1 (en) 2003-05-08
CA2396277A1 (en) 2001-07-12
GB0000079D0 (en) 2000-02-23
UY26521A1 (es) 2001-03-16
HK1046910A1 (en) 2003-01-30
DK1248784T3 (da) 2007-10-29
PL355808A1 (en) 2004-05-17
PT1248784E (pt) 2007-10-02
EE200200367A (et) 2003-12-15
UA73152C2 (en) 2005-06-15
US20060154916A1 (en) 2006-07-13
SK287005B6 (sk) 2009-09-07
CA2396277C (en) 2012-03-20
ATE366730T1 (de) 2007-08-15
IL149528A0 (en) 2002-11-10
JP2003519228A (ja) 2003-06-17
MXPA02006546A (es) 2002-12-09
NO20023137L (no) 2002-06-27
HK1046910B (en) 2007-08-31
PL211341B1 (pl) 2012-05-31
CZ20022305A3 (cs) 2002-10-16
NO20023137D0 (no) 2002-06-27
NO322571B1 (no) 2006-10-30
JP3813629B2 (ja) 2006-08-23
EP1248784A1 (en) 2002-10-16
KR100605466B1 (ko) 2006-07-28
DE60129298T2 (de) 2008-01-03
MY140467A (en) 2009-12-31
US7560454B2 (en) 2009-07-14
KR20020063191A (ko) 2002-08-01
HUP0203917A3 (en) 2004-07-28
RU2002120798A (ru) 2004-01-10
DE60129298D1 (de) 2007-08-23
WO2001049682A1 (en) 2001-07-12
US7074781B2 (en) 2006-07-11
BR0107414B1 (pt) 2014-09-16
SI1248784T1 (sl) 2007-12-31
ZA200205180B (en) 2004-02-05
HRP20020481A2 (en) 2004-08-31

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