MX9300616A - Compuestos antagonistas del receptor 5-hidroxitriptamina, proceso para su prepararcion y composicion farmaceutica que los contiene - Google Patents
Compuestos antagonistas del receptor 5-hidroxitriptamina, proceso para su prepararcion y composicion farmaceutica que los contieneInfo
- Publication number
- MX9300616A MX9300616A MX9300616A MX9300616A MX9300616A MX 9300616 A MX9300616 A MX 9300616A MX 9300616 A MX9300616 A MX 9300616A MX 9300616 A MX9300616 A MX 9300616A MX 9300616 A MX9300616 A MX 9300616A
- Authority
- MX
- Mexico
- Prior art keywords
- hydroxyriptamine
- receptor
- preparation
- pharmaceutical composition
- composition containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invención se refiere a compuestos de la fórmula (I) y sales de los mismos aceptables farmacéuticamente y a su uso como farmacéuticos en el tratamiento de desórdenes gastrointestinales, desórdenes cardiovasculares y desórdenes de SNC.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB929202510A GB9202510D0 (en) | 1992-02-06 | 1992-02-06 | Pharmaceuticals |
GB929215499A GB9215499D0 (en) | 1992-07-21 | 1992-07-21 | Pharmaceuticals |
GB929221446A GB9221446D0 (en) | 1992-10-13 | 1992-10-13 | Pharmaceuticals |
GB929225788A GB9225788D0 (en) | 1992-12-10 | 1992-12-10 | Pharmaceuticals |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9300616A true MX9300616A (es) | 1993-09-01 |
Family
ID=27450819
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9300616A MX9300616A (es) | 1992-02-06 | 1993-02-04 | Compuestos antagonistas del receptor 5-hidroxitriptamina, proceso para su prepararcion y composicion farmaceutica que los contiene |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0625149A1 (es) |
JP (1) | JPH07503480A (es) |
KR (1) | KR950700288A (es) |
AU (1) | AU667874B2 (es) |
CA (1) | CA2129112A1 (es) |
MX (1) | MX9300616A (es) |
NZ (1) | NZ246915A (es) |
WO (1) | WO1993016072A1 (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5998409A (en) * | 1992-03-12 | 1999-12-07 | Smithkline Beecham Plc | Condensed indole derivatives as 5HT4 -receptor antagonists |
US5708174A (en) * | 1992-03-12 | 1998-01-13 | Smithkline Beecham P.L.C. | Heterocyclic-esters or -amides used as 5-HT4 receptor antagonists |
US5852014A (en) * | 1992-03-12 | 1998-12-22 | Smithkline Beecham P.L.C. | Condensed indole derivatives as 5HT4 -receptor antagonists |
US5763459A (en) * | 1992-05-23 | 1998-06-09 | Smithkline Beecham P.L.C. | Medicaments for the treatment of anxiety |
AU4350493A (en) * | 1992-06-27 | 1994-01-24 | Smithkline Beecham Plc | Medicaments containing 5-ht4 receptor antagonists |
GB9219163D0 (en) * | 1992-09-10 | 1992-10-28 | Smithkline Beecham Plc | Pharmaceuticals |
MX9305947A (es) * | 1992-09-29 | 1994-06-30 | Smithkline Beecham Plc | Compuestos antagonistas del receptor 5-ht4, procedimiento para su preparacion y composiciones farmaceuticas que las contienen. |
MX9306311A (es) * | 1992-10-13 | 1994-04-29 | Smithkline Beecham Plc | Compuestos antagonistas del receptor de 5-ht4, procedimiento para su preparacion y composiciones farmaceuticas que los contienen |
US5726187A (en) * | 1992-10-16 | 1998-03-10 | Smithkline Beecham Plc | N-alkylpiperidinyl-4-methyl carboxylic esters/amides of condensed ring systems as 5-HT4 receptor antagonists |
GB9303340D0 (en) * | 1993-02-19 | 1993-04-07 | Smithkline Beecham Plc | Pharmaceuticals |
GB9507882D0 (en) * | 1995-04-18 | 1995-05-31 | Pharmacia Spa | Substituted dihydrobenzofuran derivatives as 5-ht4 agonists |
DE69602970T2 (de) * | 1995-11-09 | 2000-01-20 | Sanofi-Synthelabo, Paris | 5-(phenyl)-3-(4-piperidinyl)-1,3,4-oxadiazol-2(3h)-on-derivate verwendbar als 5-ht4- oder h3-rezeptorliganden |
FR2745574B1 (fr) * | 1996-03-04 | 1998-04-03 | Synthelabo | Derives de 5-phenyl-3-(piperidin-4-yl)-1, 3, 4-oxadiazol-2 (3h)-one, leur preparation et leur application en therapeutique |
TW445263B (en) * | 1996-02-29 | 2001-07-11 | Janssen Pharmaceutica Nv | Novel esters of 1,4-disubstituted piperidine derivatives |
FR2762316B1 (fr) * | 1997-04-18 | 1999-12-17 | Sanofi Synthelabo | Derives de 5-aryl-3-(8-azabicyclo[3.2.1] octan-3-yl)-1,3,4- oxadiazol-2(3h)-one, leur preparation et leur application en therapeutique |
FR2763068B1 (fr) | 1997-05-06 | 1999-06-04 | Synthelabo | Derives de 3-(pyrrolidin-3-yl)-1,3,4-oxadiazol-2(3h)-one, leur preparation et leur application en therapeutique |
TW402591B (en) | 1997-07-11 | 2000-08-21 | Janssen Pharmaceutica Nv | Monocyclic benzamides of 3- or 4-substituted 4-(aminomethyl)-piperidine derivatives |
DE69935600T2 (de) * | 1998-09-10 | 2007-12-06 | F. Hoffmann-La Roche Ag | Dihydrobenzodioxincarbonsäureamid- und ketonderivate als 5-ht4-rezeptorantagonisten |
TW570920B (en) * | 1998-12-22 | 2004-01-11 | Janssen Pharmaceutica Nv | 4-(aminomethyl)-piperidine benzamides for treating gastrointestinal disorders |
ATE373651T1 (de) * | 2003-06-19 | 2007-10-15 | Janssen Pharmaceutica Nv | 4-(aminomethyl)-piperidinbenzamide als 5ht4- antagonisten |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS59186969A (ja) * | 1983-04-08 | 1984-10-23 | Yoshitomi Pharmaceut Ind Ltd | ベンゾフラン−およびベンゾピランカルボキサミド誘導体 |
US4888353A (en) * | 1986-02-28 | 1989-12-19 | Erbamont, Inc. | Carboxamides useful as antiemetic or antipsychotic agents |
CA1297877C (en) * | 1983-12-22 | 1992-03-24 | Daniel Lednicer | Benzofurancarboxamides useful as antiemetic or antipsychotic agents |
US5122528A (en) * | 1983-12-22 | 1992-06-16 | Erbamont, Inc. | Analgesic use of benzobicyclic carboxamides |
SE8503055D0 (sv) * | 1985-06-19 | 1985-06-19 | Astra Laekemedel Ab | Piperonylcarboxamido derivatives |
FR2593504B1 (fr) * | 1986-01-30 | 1988-12-09 | Ile De France | Nouveaux derives de dihydrobenzofuranne - et de chromane - carboxamides, leurs procedes de preparation et leur utilisation comme neuroleptiques |
JPS62234083A (ja) * | 1986-02-28 | 1987-10-14 | アーバモント インク ディビーエイ アドリヤ ラボラトリーズ | 鎮吐薬または精神病治療薬として有用なカルボキサミド類 |
EP0314483A1 (en) * | 1987-10-29 | 1989-05-03 | Erbamont, Inc. | Preparation of benzamides |
US5374637A (en) * | 1989-03-22 | 1994-12-20 | Janssen Pharmaceutica N.V. | N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran, dihydro-2H-benzopyran or dihydrobenzodioxin)carboxamide derivatives |
US5122361A (en) * | 1989-04-17 | 1992-06-16 | Trustees Of The University Of Pennsylvania | Dopamine receptor ligands and imaging agents |
GB9005014D0 (en) * | 1990-03-06 | 1990-05-02 | Janssen Pharmaceutica Nv | N.(4.piperidinyl)(dihydrobenzofuran or dihydro.2h.benzopyran)carboxamide derivatives |
JPH04225954A (ja) * | 1990-05-02 | 1992-08-14 | Yoshitomi Pharmaceut Ind Ltd | アミド化合物、その医薬用途および新規1−置換ピロリジンメチルアミン類 |
US5114947A (en) * | 1990-12-27 | 1992-05-19 | Erbamont Inc. | Method for alleviating anxiety using benzobicyclic carboxamides |
GB9028105D0 (en) * | 1990-12-27 | 1991-02-13 | Erba Carlo Spa | Process for the preparation of substituted benzofuran derivatives |
JPH05163270A (ja) * | 1991-05-13 | 1993-06-29 | Yoshitomi Pharmaceut Ind Ltd | ベンゾフランカルボキサミド化合物 |
JPH04364181A (ja) * | 1991-06-04 | 1992-12-16 | Yoshitomi Pharmaceut Ind Ltd | ベンゾフランカルボキサミド化合物 |
-
1993
- 1993-02-01 JP JP5513865A patent/JPH07503480A/ja active Pending
- 1993-02-01 WO PCT/GB1993/000214 patent/WO1993016072A1/en not_active Application Discontinuation
- 1993-02-01 AU AU34572/93A patent/AU667874B2/en not_active Ceased
- 1993-02-01 CA CA002129112A patent/CA2129112A1/en not_active Abandoned
- 1993-02-01 EP EP93917412A patent/EP0625149A1/en not_active Withdrawn
- 1993-02-01 NZ NZ246915A patent/NZ246915A/en unknown
- 1993-02-04 MX MX9300616A patent/MX9300616A/es unknown
-
1994
- 1994-08-05 KR KR1019940702728A patent/KR950700288A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO1993016072A1 (en) | 1993-08-19 |
EP0625149A1 (en) | 1994-11-23 |
JPH07503480A (ja) | 1995-04-13 |
KR950700288A (ko) | 1995-01-16 |
NZ246915A (en) | 1996-05-28 |
CA2129112A1 (en) | 1993-08-19 |
AU667874B2 (en) | 1996-04-18 |
AU3457293A (en) | 1993-09-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX9300616A (es) | Compuestos antagonistas del receptor 5-hidroxitriptamina, proceso para su prepararcion y composicion farmaceutica que los contiene | |
MX9301348A (es) | Nuevos compuestos que tienen actividad farmacologica, proceso para su preparacion y composicion farmaceutica que los comprende. | |
ES2153907T3 (es) | Compuestos espiro tetraciclicos, procedimiento para su preparacion y su uso como antagonistas del receptor 5ht1d. | |
SV1998000029A (es) | Compuestos de pirazina ref. pg3186 | |
MX9305947A (es) | Compuestos antagonistas del receptor 5-ht4, procedimiento para su preparacion y composiciones farmaceuticas que las contienen. | |
ES2058527T3 (es) | Derivados de pirimidina condensados procedimiento y compuestos intermedios para su preparacion y composiciones farmaceuticas que los contienen. | |
AR066982A2 (es) | Compuestos heteroaromaticos sustituidos como inhibidoress tirosin quinasa, composiciones farmaceuticas que los contiene y su uso en la preparacion de medicamentos | |
FI943687A (fi) | Uudet 11-bentsaldoksiimiestradieenijohdannaiset, menetelmät niiden valmistamiseksi ja näitä yhdisteitä sisältävät lääkeaineet | |
AR028810A1 (es) | Derivados de arilpiperazinil-ciclohexil indol, composiciones farmaceuticas que los comprenden y el uso de los mismos para la manufactura de medicamentos para el tratamiento de la depresion | |
AR001332A1 (es) | Nuevos compuestos antagonistas de la taquicinina, proceso para obtenerlos y composiciones farmaceuticas que los contienen. | |
MX9301929A (es) | Derivados de pirimidina y procedimientos para su preparacion. | |
AR023275A1 (es) | Derivados de la purina | |
MX9300407A (es) | Derivados azabiciclicos usados en la fabricacion de medicamentos, composiciones que los contienen y procedimiento para su preparacion. | |
ES2081187T3 (es) | Nuevas naftil-alquil-aminas, su procedimiento de preparacion y composiciones farmaceuticas que las contienen. | |
AR035348A1 (es) | Indoles sustituidos, composiciones farmaceuticas que los comprenden, y uso de dichos compuestos en la preparacion de medicamentos | |
AR004700A1 (es) | 1alfa, 26 dihidroxi-d-homo-vitamina d3, una composicion farmaceutica que la comprende, un procedimiento para su preparacion y el uso de los mismos en laelaboracion de un medicamento | |
AR006119A1 (es) | Compuestos de quinoxalinadionas uso de los mismos para la fabricacion de un medicamento, compuestos de quinoxalinas para producirlos y procedimiento parala preparacion de los mismos | |
MX9306311A (es) | Compuestos antagonistas del receptor de 5-ht4, procedimiento para su preparacion y composiciones farmaceuticas que los contienen | |
ES2052603T3 (es) | Derivados de bencimidazol, procedimiento para su produccion y composicion farmaceutica que los contienen. | |
ES2102144T3 (es) | Nuevos derivados de estradieno de 11-benzaldoxima-17beta metoxi-17alfa-metoximetilo un procedimiento para su produccion y productos medicinales que contienen estos compuestos. | |
MX9301157A (es) | Derivados de bencimidazolona, procedimiento para su preparacion y composiciones farmaceuticas que los contienen. | |
MX9306309A (es) | Compuestos antagonistas del receptor de 5-ht4, procedimiento para su preparacion y composiciones farmaceuticas que los contienen. | |
MX9401080A (es) | Compuestos heteroaromaticos. | |
NZ241099A (en) | Difluorostatone analogues and derivatives and pharmaceutical compositions | |
AR001769A1 (es) | Benzamida enterocinética composiciones farmacéuticas que las contienen procedimiento para la preparación de dichas composiciones farmacéuticas el uso de dichos compuestos para la manufactura de medicamentos y un procedimiento para su preparación |