AR014074A1 - Compuesto, nuevo proceso para su produccion, su uso como marcador y un metodo para la valoracion de la pureza o estabilidad a la degradacion de unamuestra de lamotrigina o una dosificacion farmaceutica que comprende lamotrigina - Google Patents
Compuesto, nuevo proceso para su produccion, su uso como marcador y un metodo para la valoracion de la pureza o estabilidad a la degradacion de unamuestra de lamotrigina o una dosificacion farmaceutica que comprende lamotriginaInfo
- Publication number
- AR014074A1 AR014074A1 ARP990101018A ARP990101018A AR014074A1 AR 014074 A1 AR014074 A1 AR 014074A1 AR P990101018 A ARP990101018 A AR P990101018A AR P990101018 A ARP990101018 A AR P990101018A AR 014074 A1 AR014074 A1 AR 014074A1
- Authority
- AR
- Argentina
- Prior art keywords
- lamotrigin
- marker
- purity
- production
- pharmaceutical dosage
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D253/075—Two hetero atoms, in positions 3 and 5
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/90—Plate chromatography, e.g. thin layer or paper chromatography
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/145555—Hetero-N
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/145555—Hetero-N
- Y10T436/147777—Plural nitrogen in the same ring [e.g., barbituates, creatinine, etc.]
Abstract
Se describe la N-(5-amino-6-(2,3-diclorofenil)-1,2,4-triazina-3-il)-2,3- diclorobenzamida, un nuevo proceso para su produccion, su uso como marcador ymétodo para la valoracion de la pureza o estabilidad a la degradacion de una muestra de lamotrigina o una dosificacion farmacéutica que comprendelamotrigina, valorando dicha muestra a partir de un compuesto seleccionado de 3-amino-6-(2,3-diclorofenil)-1,2,4-triazina-5-(4H)-ona y N-(5-amino-6-(2,3-diclorofenil)-1,2,4-triazina-3-il)-2,3-diclorobenzamida.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9812413.4A GB9812413D0 (en) | 1998-06-10 | 1998-06-10 | Compound and its use |
Publications (1)
Publication Number | Publication Date |
---|---|
AR014074A1 true AR014074A1 (es) | 2001-01-31 |
Family
ID=10833464
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP990101018A AR014074A1 (es) | 1998-06-10 | 1999-03-10 | Compuesto, nuevo proceso para su produccion, su uso como marcador y un metodo para la valoracion de la pureza o estabilidad a la degradacion de unamuestra de lamotrigina o una dosificacion farmaceutica que comprende lamotrigina |
Country Status (31)
Country | Link |
---|---|
US (1) | US6333198B1 (es) |
EP (2) | EP0963980B1 (es) |
JP (1) | JP2989189B1 (es) |
KR (1) | KR100322354B1 (es) |
CN (2) | CN1238454A (es) |
AP (3) | AP9901481A0 (es) |
AR (1) | AR014074A1 (es) |
AT (1) | ATE218552T1 (es) |
AU (1) | AU2031999A (es) |
BR (1) | BR9900984A (es) |
CA (1) | CA2265194C (es) |
DE (1) | DE69901656T2 (es) |
DK (1) | DK0963980T3 (es) |
EA (1) | EA000666B1 (es) |
ES (1) | ES2178342T3 (es) |
GB (1) | GB9812413D0 (es) |
HR (1) | HRP990074A2 (es) |
HU (1) | HUP9900592A3 (es) |
ID (1) | ID22957A (es) |
MA (1) | MA24777A1 (es) |
NO (2) | NO991151L (es) |
NZ (1) | NZ334590A (es) |
PE (1) | PE20000332A1 (es) |
PL (1) | PL331870A1 (es) |
PT (1) | PT963980E (es) |
SG (1) | SG85628A1 (es) |
SI (1) | SI0963980T1 (es) |
TR (1) | TR199900520A2 (es) |
UY (1) | UY25946A1 (es) |
YU (1) | YU12399A (es) |
ZA (1) | ZA991951B (es) |
Families Citing this family (92)
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CN113156009B (zh) * | 2021-04-20 | 2023-12-22 | 三金集团湖南三金制药有限责任公司 | 高效液相色谱分析拉莫三嗪的方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
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DK153787C (da) | 1979-06-01 | 1989-01-16 | Wellcome Found | Analogifremgangsmaade til fremstilling af substituerede 3,5-diamino-6-phenyl-1,2,4-triaziner og alfa-cyanobenzyliden-aminoguanidinforbindelser til anvendelse som mellemprodukter herved |
EP0021120B1 (en) | 1979-06-01 | 1983-04-06 | The Wellcome Foundation Limited | 3,5-diamino-1,2,4-triazine derivatives, process for preparing such compounds and pharmaceutical compositions containing them |
GB8613183D0 (en) | 1986-05-30 | 1986-07-02 | Wellcome Found | Triazine salt |
GB9426448D0 (en) * | 1994-12-30 | 1995-03-01 | Wellcome Found | Process |
WO1996020934A1 (en) * | 1994-12-30 | 1996-07-11 | The Wellcome Foundation Limited | Process for the preparation of lamotrigine |
GB9512854D0 (en) * | 1995-06-23 | 1995-08-23 | Wellcome Found | Novel formulation |
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1998
- 1998-06-10 GB GBGB9812413.4A patent/GB9812413D0/en not_active Ceased
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1999
- 1999-02-24 EA EA199900159A patent/EA000666B1/ru not_active IP Right Cessation
- 1999-02-25 SG SG9901252A patent/SG85628A1/en unknown
- 1999-03-09 KR KR1019990007632A patent/KR100322354B1/ko active IP Right Review Request
- 1999-03-09 HR HR990074A patent/HRP990074A2/hr not_active Application Discontinuation
- 1999-03-10 DK DK99200695T patent/DK0963980T3/da active
- 1999-03-10 AT AT99200695T patent/ATE218552T1/de not_active IP Right Cessation
- 1999-03-10 CN CN99103445A patent/CN1238454A/zh active Pending
- 1999-03-10 ID IDP990201D patent/ID22957A/id unknown
- 1999-03-10 NO NO991151A patent/NO991151L/no unknown
- 1999-03-10 PL PL99331870A patent/PL331870A1/xx not_active Application Discontinuation
- 1999-03-10 AR ARP990101018A patent/AR014074A1/es not_active Application Discontinuation
- 1999-03-10 ZA ZA9901951A patent/ZA991951B/xx unknown
- 1999-03-10 EP EP99200695A patent/EP0963980B1/en not_active Expired - Lifetime
- 1999-03-10 EP EP01203376A patent/EP1170588A1/en not_active Withdrawn
- 1999-03-10 PE PE1999000190A patent/PE20000332A1/es not_active Application Discontinuation
- 1999-03-10 AU AU20319/99A patent/AU2031999A/en not_active Abandoned
- 1999-03-10 US US09/265,670 patent/US6333198B1/en not_active Expired - Fee Related
- 1999-03-10 CA CA002265194A patent/CA2265194C/en not_active Expired - Fee Related
- 1999-03-10 PT PT99200695T patent/PT963980E/pt unknown
- 1999-03-10 TR TR1999/00520A patent/TR199900520A2/xx unknown
- 1999-03-10 NZ NZ334590A patent/NZ334590A/xx unknown
- 1999-03-10 YU YU12399A patent/YU12399A/sh unknown
- 1999-03-10 BR BR9900984-6A patent/BR9900984A/pt not_active IP Right Cessation
- 1999-03-10 ES ES99200695T patent/ES2178342T3/es not_active Expired - Lifetime
- 1999-03-10 AP APAP/P/1999/001481A patent/AP9901481A0/en unknown
- 1999-03-10 DE DE69901656T patent/DE69901656T2/de not_active Expired - Fee Related
- 1999-03-10 HU HU9900592A patent/HUP9900592A3/hu unknown
- 1999-03-10 MA MA25489A patent/MA24777A1/fr unknown
- 1999-03-10 SI SI9930088T patent/SI0963980T1/xx unknown
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- 1999-03-10 AP APAP/P/2001/002286A patent/AP0102286A0/en unknown
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2000
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- 2000-07-25 CN CN00122208A patent/CN1306210A/zh active Pending
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2001
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2003
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