MA24777A1 - Compose et son utilisation - Google Patents

Compose et son utilisation

Info

Publication number
MA24777A1
MA24777A1 MA25489A MA25489A MA24777A1 MA 24777 A1 MA24777 A1 MA 24777A1 MA 25489 A MA25489 A MA 25489A MA 25489 A MA25489 A MA 25489A MA 24777 A1 MA24777 A1 MA 24777A1
Authority
MA
Morocco
Prior art keywords
compound
Prior art date
Application number
MA25489A
Other languages
English (en)
Inventor
Arthur Griffith-Skinner Nigel
Anthony Hill Derek
William Packham Terence
Mary Edmeades Lorraine
Thronton Hill Graham
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10833464&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA24777(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of MA24777A1 publication Critical patent/MA24777A1/fr

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D253/00Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/061,2,4-Triazines
    • C07D253/0651,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/071,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075Two hetero atoms, in positions 3 and 5
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/90Plate chromatography, e.g. thin layer or paper chromatography
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/14Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/14Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/145555Hetero-N
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/14Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/145555Hetero-N
    • Y10T436/147777Plural nitrogen in the same ring [e.g., barbituates, creatinine, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
MA25489A 1998-06-10 1999-03-10 Compose et son utilisation MA24777A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9812413.4A GB9812413D0 (en) 1998-06-10 1998-06-10 Compound and its use

Publications (1)

Publication Number Publication Date
MA24777A1 true MA24777A1 (fr) 1999-10-01

Family

ID=10833464

Family Applications (1)

Application Number Title Priority Date Filing Date
MA25489A MA24777A1 (fr) 1998-06-10 1999-03-10 Compose et son utilisation

Country Status (31)

Country Link
US (1) US6333198B1 (fr)
EP (2) EP1170588A1 (fr)
JP (1) JP2989189B1 (fr)
KR (1) KR100322354B1 (fr)
CN (2) CN1238454A (fr)
AP (3) AP9901481A0 (fr)
AR (1) AR014074A1 (fr)
AT (1) ATE218552T1 (fr)
AU (1) AU2031999A (fr)
BR (1) BR9900984A (fr)
CA (1) CA2265194C (fr)
DE (1) DE69901656T2 (fr)
DK (1) DK0963980T3 (fr)
EA (1) EA000666B1 (fr)
ES (1) ES2178342T3 (fr)
GB (1) GB9812413D0 (fr)
HR (1) HRP990074A2 (fr)
HU (1) HUP9900592A3 (fr)
ID (1) ID22957A (fr)
MA (1) MA24777A1 (fr)
NO (2) NO991151L (fr)
NZ (1) NZ334590A (fr)
PE (1) PE20000332A1 (fr)
PL (1) PL331870A1 (fr)
PT (1) PT963980E (fr)
SG (1) SG85628A1 (fr)
SI (1) SI0963980T1 (fr)
TR (1) TR199900520A2 (fr)
UY (1) UY25946A1 (fr)
YU (1) YU12399A (fr)
ZA (1) ZA991951B (fr)

Families Citing this family (92)

* Cited by examiner, † Cited by third party
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CA2433181C (fr) 2000-12-29 2005-11-22 Pfizer Limited Fumarate d'amlodipine
US6653481B2 (en) 2000-12-29 2003-11-25 Synthon Bv Process for making amlodipine
AT5874U1 (de) 2000-12-29 2003-01-27 Bioorg Bv Pharmazeutische zubereitungen enthaltend amlodipinmaleat
CA2433284A1 (fr) 2000-12-29 2002-07-11 Pfizer Limited Standards de reference destines a la determination de la purete ou de la stabilite de maleate d'amlodipine et procedes correspondants
EP1309558A1 (fr) 2000-12-29 2003-05-14 Synthon Licensing, Ltd. Derive aspartate de l'amlodipine utilise comme antagoniste des canaux calciques
WO2002053541A1 (fr) 2000-12-29 2002-07-11 Pfizer Limited Derive d'amide d'amlodipine
AP2003002820A0 (en) 2000-12-29 2003-06-30 Pfizer Ltd "Process for making amlodipine maleate"
MXPA03005882A (es) 2000-12-29 2005-04-19 Pfizer Ltd Derivado amida de amlodipina.
US7335380B2 (en) 2000-12-29 2008-02-26 Synthon Ip Inc. Amlodipine free base
EP1309557B9 (fr) 2000-12-29 2006-11-15 Pfizer Limited Amlodipine hemimaleate
DE10134980C2 (de) * 2001-07-17 2003-05-28 Helm Ag Verfahren zur Herstellung von Lamotrigin
CA2366521C (fr) 2001-12-24 2007-03-06 Brantford Chemicals Inc. Un procede nouveau et efficace de preparation de lamotrigine et d'autres 3,5-diamino-1,2,4-triazines substituees en position 6
WO2003080065A1 (fr) * 2002-03-20 2003-10-02 Teva Pharmaceutical Industries Ltd. Formes cristallines d'hemifumarate de quetiapine
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ES2209639B1 (es) 2002-10-31 2005-08-01 Vita Cientifica, S.L. Procedimiento para la obtencion de un compuesto farmaceuticamente activo y obtencion de su intermedio.
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CA2537271A1 (fr) 2003-08-28 2005-03-17 Teva Pharmaceutical Industries, Ltd. Procede de preparation de sels calciques de rosuvastatine
CA2546701C (fr) * 2003-11-24 2010-07-27 Teva Pharmaceutical Industries Ltd. Sels d'ammonium cristallins de la rosuvastatine
WO2005056534A1 (fr) * 2003-12-02 2005-06-23 Teva Pharmaceutical Industries Ltd. Norme de reference pour la caracterisation de la rosuvastatine
US7851624B2 (en) * 2003-12-24 2010-12-14 Teva Pharamaceutical Industries Ltd. Triol form of rosuvastatin and synthesis of rosuvastatin
CA2554572A1 (fr) * 2004-01-30 2005-08-18 Teva Pharmaceutical Industries Ltd. Polymorphes d'acide sans montelukast
WO2005075427A2 (fr) * 2004-01-30 2005-08-18 Teva Pharmaceutical Industries Ltd. Montelukast de sodium polymorphe
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DE602005015174D1 (de) * 2004-04-21 2009-08-13 Teva Pharma Verfahren zur herstellung von montelukast-natrium
TW200613294A (en) * 2004-04-26 2006-05-01 Teva Gyogyszergyar Reszvenytarsasag Process for preparation of mycophenolic acid and ester derivatives thereof
US20050250773A1 (en) * 2004-04-27 2005-11-10 Sandor Molnar Process for preparation of mycophenolate mofetil and other esters of mycophenolic acid
US7439399B2 (en) * 2004-06-28 2008-10-21 Teva Pharmaceutical Fine Chemicals Processes for the preparation of atomoxetine hydrochloride
WO2006004976A2 (fr) * 2004-06-28 2006-01-12 Teva Pharmaceutical Fine Chemicals S.R.L. Fabrication d'hydrochlorure d'atomoxetine
JP2007508379A (ja) * 2004-07-13 2007-04-05 テバ ファーマシューティカル インダストリーズ リミティド Tempo媒介型酸化段階を包含するロスバスタチンの調製方法
WO2006012385A2 (fr) * 2004-07-20 2006-02-02 Teva Gyógyszergyár Zàrtköruen Muködo Rèszvènytàrsasàg Mycophenolate de sodium cristallin
WO2006020348A2 (fr) * 2004-07-22 2006-02-23 Teva Pharmaceutical Fine Chemicals S.R.L. Polymorphes du chlorhydrate d'atomoxetine
US7629461B2 (en) * 2004-09-04 2009-12-08 Teva Pharmaceutical Industries Ltd Isolated valacyclovir impurity, process for the preparation of valacyclovir impurity and use as a reference standard
US20060081361A1 (en) * 2004-09-13 2006-04-20 Gabbey Lawrence W Oil cooler with integral filter
WO2006037125A1 (fr) * 2004-09-28 2006-04-06 Teva Pharmaceutical Industries Ltd. Procede de preparation de formes d'atorvastatine calcique sensiblement exemptes d'impuretes
WO2006045120A2 (fr) * 2004-10-19 2006-04-27 Teva Pharmaceutical Industries Ltd. Purification du maleate de tegaserod
US7678551B2 (en) * 2004-10-25 2010-03-16 Seradyn, Inc. Immunoassays for lamotrigine
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CA2591666A1 (fr) * 2005-01-11 2006-07-20 Teva Pharmaceutical Fine Chemicals S.R.L. Procede de preparation du chlorhydrate 1-amino-3,5-dimethyladamantane
US20070037979A1 (en) * 2005-02-22 2007-02-15 Valerie Niddam-Hildesheim Preparation of rosuvastatin
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WO2006122258A1 (fr) * 2005-05-10 2006-11-16 Teva Pharmaceutical Industries Ltd. Procede pour preparer de la pregabaline et des sels de celle-ci
WO2006121557A1 (fr) * 2005-05-10 2006-11-16 Teva Pharmaceutical Industries Ltd. Pregabaline exempte de lactame et son procede de preparation
WO2006127933A1 (fr) 2005-05-23 2006-11-30 Teva Pharmaceutical Industries Ltd. Procedes d'elaboration de forme i cristalline d'hydrochlorure de cinacalcet
WO2007002722A2 (fr) * 2005-06-27 2007-01-04 Sicor, Inc. Procédé de purification d'un intermédiaire de l'anastrozole
EP1896398A2 (fr) * 2005-06-27 2008-03-12 Sicor Inc. Impureté d'un intermédiaire de l'anastrozole, et ses applications
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US7446220B2 (en) * 2005-09-19 2008-11-04 Teva Pharmaceutical Industries Ltd. Asymmetric synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid
US20070197529A1 (en) * 2005-12-01 2007-08-23 Viviana Braude Isolated desfluoro-linezolid, preparation thereof and its use as a reference marker and standard
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WO2007069264A2 (fr) * 2005-12-15 2007-06-21 Alembic Limited Nouveaux composes
CA2626715A1 (fr) * 2005-12-27 2007-07-05 Teva Pharmaceutical Industries Ltd. Procedes de preparation de bromhydrate de darifenacine
WO2007126886A1 (fr) * 2006-03-27 2007-11-08 Teva Pharmaceuticals Usa, Inc. Procédé de synthèse de chlorhydrate de mémantine ne contenant essentiellement aucune impureté
US20080146675A1 (en) * 2006-04-05 2008-06-19 Eugenio Castelli Stable Atomoxetine Hydrochloride, a process for the preparation thereof, and an analytical control of its stability
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WO2007139933A2 (fr) * 2006-05-24 2007-12-06 Teva Pharmaceutical Industries Ltd. Procédés pour la préparation d'acide r-(+)-3-(carbamoyl méthyl)-5-méthylhexanoïque et de sels de celui-ci
EP2071032A3 (fr) * 2006-05-31 2009-07-08 Teva Pharmaceutical Industries Ltd Utilisation d'une résolution enzymatique pour la préparation d'intermédiaires de la prégabaline
EP1912931A2 (fr) * 2006-05-31 2008-04-23 Teva Pharmaceutical Industries Ltd. Préparation de (s)-prégabaline nitrile
SI2032712T1 (sl) * 2006-06-29 2010-06-30 Ivax Pharmaceuticals Sro Regulacija proizvodnje kislinskega metabolita
US20120142919A1 (en) * 2006-08-02 2012-06-07 Medichem, S.A. Method for synthesizing lamotrigine
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WO2008106179A1 (fr) * 2007-02-26 2008-09-04 Teva Pharmaceutical Industries Ltd. Intermédiaires et procédés pour la synthèse de ramelteon
KR101036536B1 (ko) * 2007-03-22 2011-05-24 테바 파마슈티컬 인더스트리즈 리미티드 (s)-(+)-3-(아미노메틸)-5-메틸 헥산산의 합성
EP2024506A1 (fr) * 2007-04-11 2009-02-18 Teva Gyógyszergyár Zártköruen Muködo Részvénytársaság Procédé de réduction du niveau d'impuretés dans une fermentation d'acide mycophénolique
EP2069320A2 (fr) * 2007-05-31 2009-06-17 Teva Pharmaceutical Industries Ltd. Procédé de synthèse du rameltéon et ses intermédiaires
US20090137842A1 (en) * 2007-10-03 2009-05-28 Vollerner Yuri Pregabalin -4-eliminate, pregabalin 5-eliminate, their use as reference marker and standard, and method to produce pregabalin containing low levels thereof
US8067423B2 (en) * 2007-10-23 2011-11-29 Teva Pharmaceutical Industries Ltd. Polymorphs of dasatinib isopropyl alcohol and process for preparation thereof
WO2009056993A2 (fr) * 2007-11-01 2009-05-07 Teva Pharmaceutical Industries Ltd. Procédé de synthèse de rameltéon et intermédiaires de ce dernier
US8486927B2 (en) * 2007-11-09 2013-07-16 Thar Pharmaceuticals Crystalline forms of lamotrigine
EP2252574A1 (fr) * 2008-03-06 2010-11-24 Teva Pharmaceutical Industries Ltd. Procédés de préparation de la o-desméthylvenlafaxine, exempte de ses impuretés dimères
EP2297090A1 (fr) * 2008-06-23 2011-03-23 Teva Pharmaceutical Industries Ltd. Synthèse enzymatique stéréosélective de l ester (s) ou (r)-isobutylglutarique
WO2010045565A1 (fr) * 2008-10-16 2010-04-22 Teva Pharmaceutical Industries Ltd. Procédé de synthèse du ramelteon et de ses intermédiaires
CA2795023A1 (fr) * 2010-03-29 2011-10-06 Pliva Hrvatska D.O.O. Formes cristallines du fumarate de o-desmethylvenlafaxine
WO2012034065A1 (fr) 2010-09-09 2012-03-15 Teva Pharmaceutical Industries Ltd. Intermédiaires d'aliskirène et procédé destiné à analyser la pureté de l'aliskirène
CN102766104A (zh) * 2012-08-20 2012-11-07 三金集团湖南三金制药有限责任公司 一种治疗双向情感障碍及癫痫病药物拉莫三嗪的合成方法
WO2015092819A2 (fr) 2013-12-21 2015-06-25 Nektar Therapeutics (India) Pvt. Ltd. Dérivés de 6- (2,3-dichlorophényl) -1,2,4-triazin -5-amine
CN110467560A (zh) 2018-05-09 2019-11-19 深圳微芯生物科技股份有限公司 一种苯基氨基丙酸钠衍生物、其制备方法和应用
KR102270026B1 (ko) * 2020-01-31 2021-06-28 현대약품 주식회사 (3s)-3-(4-(3-(1,4-다이옥사스파이로[4,5]데스-7-엔-8-일)벤질옥시)페닐)헥스-4-이노익산의 품질 평가 방법
CN113156009B (zh) * 2021-04-20 2023-12-22 三金集团湖南三金制药有限责任公司 高效液相色谱分析拉莫三嗪的方法

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Publication number Priority date Publication date Assignee Title
JPS5625169A (en) 1979-06-01 1981-03-10 Wellcome Found Triazine derivative
EP0021120B1 (fr) 1979-06-01 1983-04-06 The Wellcome Foundation Limited Dérivés de la diamino-3,5 triazine-1,2,4, procédé pour la préparation de tels composés et compositions pharmaceutiques les contenant
GB8613183D0 (en) 1986-05-30 1986-07-02 Wellcome Found Triazine salt
GB9426448D0 (en) * 1994-12-30 1995-03-01 Wellcome Found Process
RU2145602C1 (ru) * 1994-12-30 2000-02-20 Де Вэллкам Фаундейшн Лимитед Способы получения ламотриджина, промежуточные соединения и способ получения фармацевтической композиции
GB9512854D0 (en) * 1995-06-23 1995-08-23 Wellcome Found Novel formulation

Also Published As

Publication number Publication date
PE20000332A1 (es) 2000-04-10
SG85628A1 (en) 2002-01-15
HU9900592D0 (en) 1999-04-28
EP1170588A1 (fr) 2002-01-09
TR199900520A3 (tr) 2000-01-21
DK0963980T3 (da) 2002-09-16
KR100322354B1 (ko) 2002-02-07
HRP990074A2 (en) 2000-10-31
SI0963980T1 (en) 2002-12-31
NZ334590A (en) 2000-07-28
NO991151D0 (no) 1999-03-10
PL331870A1 (en) 1999-12-20
HUP9900592A2 (hu) 2000-04-28
AP2001002286A0 (en) 2001-12-31
AP9901481A0 (en) 1999-03-31
AR014074A1 (es) 2001-01-31
EP0963980A2 (fr) 1999-12-15
US6333198B1 (en) 2001-12-25
AU2031999A (en) 2000-01-06
JP2000009714A (ja) 2000-01-14
EA000666B1 (ru) 2000-02-28
NO20032753D0 (no) 2003-06-17
NO991151L (no) 1999-12-13
ATE218552T1 (de) 2002-06-15
EA199900159A1 (ru) 1999-12-29
HUP9900592A3 (en) 2002-04-29
JP2989189B1 (ja) 1999-12-13
ZA991951B (en) 1999-08-16
CN1306210A (zh) 2001-08-01
PT963980E (pt) 2002-10-31
AP0102286A0 (en) 2000-09-10
NO20032753L (no) 1999-12-13
UY25946A1 (es) 2000-12-29
EP0963980B1 (fr) 2002-06-05
CN1238454A (zh) 1999-12-15
ES2178342T3 (es) 2002-12-16
DE69901656T2 (de) 2003-01-30
KR20000005611A (ko) 2000-01-25
GB9812413D0 (en) 1998-08-05
EP0963980A3 (fr) 2000-05-31
ID22957A (id) 1999-12-23
TR199900520A2 (en) 2000-01-21
DE69901656D1 (de) 2002-07-11
BR9900984A (pt) 2000-05-02
YU12399A (sh) 2002-08-12
CA2265194C (fr) 2000-10-10

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