SI2032712T1 - Regulacija proizvodnje kislinskega metabolita - Google Patents

Regulacija proizvodnje kislinskega metabolita

Info

Publication number
SI2032712T1
SI2032712T1 SI200730216T SI200730216T SI2032712T1 SI 2032712 T1 SI2032712 T1 SI 2032712T1 SI 200730216 T SI200730216 T SI 200730216T SI 200730216 T SI200730216 T SI 200730216T SI 2032712 T1 SI2032712 T1 SI 2032712T1
Authority
SI
Slovenia
Prior art keywords
regulation
acid metabolite
metabolite production
acid
mycophenolic acid
Prior art date
Application number
SI200730216T
Other languages
English (en)
Inventor
Zdenek Pokluda
Josef Satke
Vladimir Vala
Josef Valik
Original Assignee
Ivax Pharmaceuticals Sro
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ivax Pharmaceuticals Sro filed Critical Ivax Pharmaceuticals Sro
Publication of SI2032712T1 publication Critical patent/SI2032712T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SI200730216T 2006-06-29 2007-06-29 Regulacija proizvodnje kislinskega metabolita SI2032712T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US81814506P 2006-06-29 2006-06-29
US84734406P 2006-09-25 2006-09-25
EP07796600A EP2032712B1 (en) 2006-06-29 2007-06-29 Regulation of acid metabolite production
PCT/US2007/015234 WO2008002665A1 (en) 2006-06-29 2007-06-29 Regulation of acid metabolite production

Publications (1)

Publication Number Publication Date
SI2032712T1 true SI2032712T1 (sl) 2010-06-30

Family

ID=38626338

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200730216T SI2032712T1 (sl) 2006-06-29 2007-06-29 Regulacija proizvodnje kislinskega metabolita

Country Status (12)

Country Link
US (1) US20080009050A1 (sl)
EP (1) EP2032712B1 (sl)
JP (1) JP2009505681A (sl)
KR (1) KR20080069571A (sl)
AT (1) ATE457358T1 (sl)
BR (1) BRPI0702901A2 (sl)
DE (1) DE602007004728D1 (sl)
DK (1) DK2032712T3 (sl)
ES (1) ES2339297T3 (sl)
PL (1) PL2032712T3 (sl)
SI (1) SI2032712T1 (sl)
WO (1) WO2008002665A1 (sl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080254520A1 (en) * 2007-04-11 2008-10-16 Eva Gulyas Method for reducing impurity level in mycophenolic acid fermentation
CN109929890B (zh) * 2019-05-08 2020-12-04 广东蓝宝制药有限公司 一种麦考酚酸的发酵工艺

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4115197A (en) * 1977-03-21 1978-09-19 Eli Lilly And Company Procedure for obtaining penicillium species mutants with improved ability to synthesize mycophenolic acid
AT401182B (de) * 1993-03-10 1996-07-25 Forschungszentrum Juelich Gmbh Fermentationsverfahren zur kontinuierlichen citronensäuregewinnung
US6225073B1 (en) * 1994-07-07 2001-05-01 Dade Behring Marburg Gmbh Immunoassay for mycophenolic acid
ID18663A (id) * 1996-04-12 1998-04-30 Novartis Ag Komposisi farmasi berlapis enterik
US6083728A (en) * 1997-10-17 2000-07-04 Regents Of The University Of Minnesota Production of glutamate using wild type Bacillus methanolicus
GB9812413D0 (en) * 1998-06-10 1998-08-05 Glaxo Group Ltd Compound and its use
US6107052A (en) * 1999-06-09 2000-08-22 Roche Diagnostics Corporation Enzymatic measurement of mycophenolic acid
JP2003525052A (ja) * 2000-02-29 2003-08-26 バイオコン・インディア・リミテッド マイコフェノール酸の製造および精製
CZ292123B6 (cs) * 2001-06-08 2003-08-13 Ivax Pharmaceuticals S.R.O. Způsob přípravy mykofenolátu mofetilu
ATE447563T1 (de) * 2002-08-29 2009-11-15 Biocon Ltd Verfahren zur herstellung eines immunosuppresivums
US6955892B2 (en) * 2002-11-12 2005-10-18 Akzo Nobel N.V. Feeding processes for fermentation
PL1667987T3 (pl) * 2003-09-11 2009-01-30 Sandoz Ag Sposób wytwarzania mykofenolanu mofetylu
BRPI0506798A (pt) * 2004-02-20 2007-05-22 Ivax Pharmaceuticals Sro processo para a fabricação de ácido lisérgico
EP1740564A2 (en) * 2004-04-26 2007-01-10 Teva Gyógyszergyár Zártköruen Muködo Részvenytarsaság Process for preparation of mycophenolic acid and ester derivatives thereof
WO2005105771A1 (en) * 2004-04-27 2005-11-10 Teva Gyógyszergyár Zàrtköruen Muködo Rèszvènytàrsasàg Process for preparation of mycophenolate mofetil and other esters of mycophenolic acid
JP2008506784A (ja) * 2004-07-20 2008-03-06 テバ ジョジセルジャール ザ−トケルエン ムケド レ−スベニュタ−ルシャシャ−グ 結晶形ミコフェノール酸・ナトリウム
EP2166108A1 (en) * 2004-08-05 2010-03-24 Tecnimede-Sociedade Tecnico-Medicinal, S.A. Improved process for the production of mycophenolic acid
US7138504B2 (en) * 2004-08-12 2006-11-21 Microgenics Corporation Reagents and methods for mycophenolic acid immunoassay

Also Published As

Publication number Publication date
JP2009505681A (ja) 2009-02-12
EP2032712A1 (en) 2009-03-11
ES2339297T3 (es) 2010-05-18
EP2032712B1 (en) 2010-02-10
KR20080069571A (ko) 2008-07-28
ATE457358T1 (de) 2010-02-15
DE602007004728D1 (de) 2010-03-25
BRPI0702901A2 (pt) 2011-03-15
US20080009050A1 (en) 2008-01-10
WO2008002665A1 (en) 2008-01-03
PL2032712T3 (pl) 2010-07-30
DK2032712T3 (da) 2010-05-25

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