DK2032712T3 - Regulering af syremetabolitproduktion - Google Patents

Regulering af syremetabolitproduktion

Info

Publication number
DK2032712T3
DK2032712T3 DK07796600.0T DK07796600T DK2032712T3 DK 2032712 T3 DK2032712 T3 DK 2032712T3 DK 07796600 T DK07796600 T DK 07796600T DK 2032712 T3 DK2032712 T3 DK 2032712T3
Authority
DK
Denmark
Prior art keywords
regulation
acid metabolite
metabolite production
acid
mycophenolic acid
Prior art date
Application number
DK07796600.0T
Other languages
English (en)
Inventor
Zdenek Pokluda
Josef Satke
Josef Valik
Vladimir Vala
Original Assignee
Ivax Pharmaceuticals Sro
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ivax Pharmaceuticals Sro filed Critical Ivax Pharmaceuticals Sro
Application granted granted Critical
Publication of DK2032712T3 publication Critical patent/DK2032712T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK07796600.0T 2006-06-29 2007-06-29 Regulering af syremetabolitproduktion DK2032712T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81814506P 2006-06-29 2006-06-29
US84734406P 2006-09-25 2006-09-25
PCT/US2007/015234 WO2008002665A1 (en) 2006-06-29 2007-06-29 Regulation of acid metabolite production

Publications (1)

Publication Number Publication Date
DK2032712T3 true DK2032712T3 (da) 2010-05-25

Family

ID=38626338

Family Applications (1)

Application Number Title Priority Date Filing Date
DK07796600.0T DK2032712T3 (da) 2006-06-29 2007-06-29 Regulering af syremetabolitproduktion

Country Status (12)

Country Link
US (1) US20080009050A1 (da)
EP (1) EP2032712B1 (da)
JP (1) JP2009505681A (da)
KR (1) KR20080069571A (da)
AT (1) ATE457358T1 (da)
BR (1) BRPI0702901A2 (da)
DE (1) DE602007004728D1 (da)
DK (1) DK2032712T3 (da)
ES (1) ES2339297T3 (da)
PL (1) PL2032712T3 (da)
SI (1) SI2032712T1 (da)
WO (1) WO2008002665A1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2024506A1 (en) * 2007-04-11 2009-02-18 Teva Gyógyszergyár Zártköruen Muködo Részvénytársaság Method for reducing impurity level in mycophenolic acid fermentation
CN109929890B (zh) * 2019-05-08 2020-12-04 广东蓝宝制药有限公司 一种麦考酚酸的发酵工艺

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4115197A (en) * 1977-03-21 1978-09-19 Eli Lilly And Company Procedure for obtaining penicillium species mutants with improved ability to synthesize mycophenolic acid
DE4407441C2 (de) * 1993-03-10 1996-02-29 Forschungszentrum Juelich Gmbh Fermentationsverfahren zur kontinuierlichen Citronensäuregewinnung
US6225073B1 (en) * 1994-07-07 2001-05-01 Dade Behring Marburg Gmbh Immunoassay for mycophenolic acid
ID18663A (id) * 1996-04-12 1998-04-30 Novartis Ag Komposisi farmasi berlapis enterik
US6083728A (en) * 1997-10-17 2000-07-04 Regents Of The University Of Minnesota Production of glutamate using wild type Bacillus methanolicus
GB9812413D0 (en) * 1998-06-10 1998-08-05 Glaxo Group Ltd Compound and its use
US6107052A (en) * 1999-06-09 2000-08-22 Roche Diagnostics Corporation Enzymatic measurement of mycophenolic acid
CZ20022913A3 (cs) * 2000-02-29 2003-02-12 Biocon India Limited Výroba a čištění kyseliny mykofenolové
CZ292123B6 (cs) * 2001-06-08 2003-08-13 Ivax Pharmaceuticals S.R.O. Způsob přípravy mykofenolátu mofetilu
KR100551617B1 (ko) * 2002-08-29 2006-02-13 바이오콘 리미티드 면역억제제의 제조방법
US6955892B2 (en) * 2002-11-12 2005-10-18 Akzo Nobel N.V. Feeding processes for fermentation
CA2537958C (en) * 2003-09-11 2013-06-11 Sandoz Ag Process for the production of mycophenolate mofetil
US20070135638A1 (en) * 2004-02-20 2007-06-14 Ivax Pharmaceuticals S.R.O. Process for the manufacture of lysergic acid
EP1740564A2 (en) * 2004-04-26 2007-01-10 Teva Gyógyszergyár Zártköruen Muködo Részvenytarsaság Process for preparation of mycophenolic acid and ester derivatives thereof
WO2005105769A2 (en) * 2004-04-27 2005-11-10 Teva Gyógyszergyár Zàrtköruen Muködo Rèszvènytàrsasàg - Mycophenolate mofetil impurity
WO2006012385A2 (en) * 2004-07-20 2006-02-02 Teva Gyógyszergyár Zàrtköruen Muködo Rèszvènytàrsasàg Crystalline mycophenolate sodium
EP2166108A1 (en) * 2004-08-05 2010-03-24 Tecnimede-Sociedade Tecnico-Medicinal, S.A. Improved process for the production of mycophenolic acid
US7138504B2 (en) * 2004-08-12 2006-11-21 Microgenics Corporation Reagents and methods for mycophenolic acid immunoassay

Also Published As

Publication number Publication date
PL2032712T3 (pl) 2010-07-30
SI2032712T1 (sl) 2010-06-30
ATE457358T1 (de) 2010-02-15
EP2032712A1 (en) 2009-03-11
KR20080069571A (ko) 2008-07-28
DE602007004728D1 (de) 2010-03-25
BRPI0702901A2 (pt) 2011-03-15
EP2032712B1 (en) 2010-02-10
WO2008002665A1 (en) 2008-01-03
US20080009050A1 (en) 2008-01-10
ES2339297T3 (es) 2010-05-18
JP2009505681A (ja) 2009-02-12

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