SG85628A1 - Compound and its use - Google Patents
Compound and its useInfo
- Publication number
- SG85628A1 SG85628A1 SG9901252A SG1999001252A SG85628A1 SG 85628 A1 SG85628 A1 SG 85628A1 SG 9901252 A SG9901252 A SG 9901252A SG 1999001252 A SG1999001252 A SG 1999001252A SG 85628 A1 SG85628 A1 SG 85628A1
- Authority
- SG
- Singapore
- Prior art keywords
- compound
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D253/075—Two hetero atoms, in positions 3 and 5
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/90—Plate chromatography, e.g. thin layer or paper chromatography
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/145555—Hetero-N
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/145555—Hetero-N
- Y10T436/147777—Plural nitrogen in the same ring [e.g., barbituates, creatinine, etc.]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Plural Heterocyclic Compounds (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9812413.4A GB9812413D0 (en) | 1998-06-10 | 1998-06-10 | Compound and its use |
Publications (1)
Publication Number | Publication Date |
---|---|
SG85628A1 true SG85628A1 (en) | 2002-01-15 |
Family
ID=10833464
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG9901252A SG85628A1 (en) | 1998-06-10 | 1999-02-25 | Compound and its use |
Country Status (31)
Country | Link |
---|---|
US (1) | US6333198B1 (fr) |
EP (2) | EP1170588A1 (fr) |
JP (1) | JP2989189B1 (fr) |
KR (1) | KR100322354B1 (fr) |
CN (2) | CN1238454A (fr) |
AP (3) | AP9901481A0 (fr) |
AR (1) | AR014074A1 (fr) |
AT (1) | ATE218552T1 (fr) |
AU (1) | AU2031999A (fr) |
BR (1) | BR9900984A (fr) |
CA (1) | CA2265194C (fr) |
DE (1) | DE69901656T2 (fr) |
DK (1) | DK0963980T3 (fr) |
EA (1) | EA000666B1 (fr) |
ES (1) | ES2178342T3 (fr) |
GB (1) | GB9812413D0 (fr) |
HR (1) | HRP990074A2 (fr) |
HU (1) | HUP9900592A3 (fr) |
ID (1) | ID22957A (fr) |
MA (1) | MA24777A1 (fr) |
NO (2) | NO991151L (fr) |
NZ (1) | NZ334590A (fr) |
PE (1) | PE20000332A1 (fr) |
PL (1) | PL331870A1 (fr) |
PT (1) | PT963980E (fr) |
SG (1) | SG85628A1 (fr) |
SI (1) | SI0963980T1 (fr) |
TR (1) | TR199900520A3 (fr) |
UY (1) | UY25946A1 (fr) |
YU (1) | YU12399A (fr) |
ZA (1) | ZA991951B (fr) |
Families Citing this family (92)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020055177A1 (en) * | 1999-03-10 | 2002-05-09 | Glaxo Wellcome Inc. | Compound and its use |
AU763244B2 (en) * | 2000-01-03 | 2003-07-17 | Rpg Life Sciences Limited | A process for the preparation of 6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine, commonly known as lamotrigine |
CN1272319C (zh) | 2000-12-29 | 2006-08-30 | 辉瑞有限公司 | 制备氨氯地平马来酸盐的工艺、所制得的氨氯地平马来酸盐、其药物组合物和用途 |
WO2002054062A2 (fr) * | 2000-12-29 | 2002-07-11 | Pfizer Limited | Standards de reference destines a la determination de la purete ou de la stabilite de maleate d'amlodipine et procedes correspondants |
BR0116553A (pt) | 2000-12-29 | 2004-02-03 | Pfizer Ltd | Composto, composição farmacêutica para tratamento de angina ou hipertensão, processo, processo para tratamento ou prevenção de angina ou hipertensão, composição de ingredientes farmaceuticamente ativos, composição farmacêutica para tratamento ou prevenção de angina ou hipertensão e processo para tratar ou prevenir angina ou hipertensão |
EP1309556B1 (fr) | 2000-12-29 | 2004-11-24 | Pfizer Limited | Fumarate d'amlodipine |
AT5874U1 (de) | 2000-12-29 | 2003-01-27 | Bioorg Bv | Pharmazeutische zubereitungen enthaltend amlodipinmaleat |
MXPA03005882A (es) | 2000-12-29 | 2005-04-19 | Pfizer Ltd | Derivado amida de amlodipina. |
EP1309554A1 (fr) | 2000-12-29 | 2003-05-14 | Synthon Licensing, Ltd. | Derive d'amide d'amlodipine |
US6653481B2 (en) | 2000-12-29 | 2003-11-25 | Synthon Bv | Process for making amlodipine |
US7335380B2 (en) | 2000-12-29 | 2008-02-26 | Synthon Ip Inc. | Amlodipine free base |
ATE315026T1 (de) | 2000-12-29 | 2006-02-15 | Pfizer Ltd | Amlodipin-hemimaleat |
DE10134980C2 (de) * | 2001-07-17 | 2003-05-28 | Helm Ag | Verfahren zur Herstellung von Lamotrigin |
CA2366521C (fr) | 2001-12-24 | 2007-03-06 | Brantford Chemicals Inc. | Un procede nouveau et efficace de preparation de lamotrigine et d'autres 3,5-diamino-1,2,4-triazines substituees en position 6 |
US20030216376A1 (en) * | 2002-03-20 | 2003-11-20 | Revital Lifshitz-Liron | Crystalline forms of quetiapine hemifumarate |
HU225667B1 (en) * | 2002-09-20 | 2007-05-29 | Richter Gedeon Nyrt | Method for producing high-purity 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine |
ES2209639B1 (es) | 2002-10-31 | 2005-08-01 | Vita Cientifica, S.L. | Procedimiento para la obtencion de un compuesto farmaceuticamente activo y obtencion de su intermedio. |
GB2395483A (en) * | 2003-07-03 | 2004-05-26 | Jubilant Organosys Ltd | Crystalline lamotrigine and its monohydrate |
WO2005023778A2 (fr) | 2003-08-28 | 2005-03-17 | Teva Pharmaceutical Industries Ltd. | Procede de preparation de sels calciques de rosuvastatine |
TW200526596A (en) * | 2003-11-24 | 2005-08-16 | Teva Pharma | Crystalline ammonium salts of rosuvastatin |
US7244844B2 (en) * | 2003-12-02 | 2007-07-17 | Teva Pharmaceutical Industries Ltd. | Reference standard for characterization of rosuvastatin |
US7851624B2 (en) * | 2003-12-24 | 2010-12-14 | Teva Pharamaceutical Industries Ltd. | Triol form of rosuvastatin and synthesis of rosuvastatin |
KR20060117356A (ko) * | 2004-01-30 | 2006-11-16 | 테바 파마슈티컬 인더스트리즈 리미티드 | 몬테루카스트 유리산 다형체 |
WO2005075427A2 (fr) * | 2004-01-30 | 2005-08-18 | Teva Pharmaceutical Industries Ltd. | Montelukast de sodium polymorphe |
MD2823G2 (ro) * | 2004-02-12 | 2006-05-31 | Институт Химии Академии Наук Молдовы | Procedeu de determinare cantitativă a sclareolului în extractele, obţinute din salvia de muscat |
MXPA06012220A (es) * | 2004-04-21 | 2007-07-18 | Teva Pharma | Procesos para preparar sodio de montelukast. |
EP1740564A2 (fr) * | 2004-04-26 | 2007-01-10 | Teva Gyógyszergyár Zártköruen Muködo Részvenytarsaság | Processus de préparation d'acide mycophénolique et de dérivés d'ester |
MXPA06005658A (es) * | 2004-04-27 | 2007-04-10 | Teva Gyogyszergyar Zartkoruen | Proceso para preparacion de micofenolato mofetil, y otros esteres de acido micofenolico. |
US7355078B2 (en) * | 2004-06-28 | 2008-04-08 | Teva Pharmaceutical Fine Chemicals S.R.L. | Processes for the preparation of tomoxetine |
US7439399B2 (en) * | 2004-06-28 | 2008-10-21 | Teva Pharmaceutical Fine Chemicals | Processes for the preparation of atomoxetine hydrochloride |
CA2573857A1 (fr) * | 2004-07-13 | 2006-02-16 | Teva Pharmaceutical Industries Ltd. | Procede pour la preparation de rosuvastatine mettant en oeuvre une etape d'oxydation par tempo |
CN101052631A (zh) * | 2004-07-20 | 2007-10-10 | 特瓦药厂私人有限公司 | 结晶霉酚酸钠 |
CN1976894A (zh) * | 2004-07-22 | 2007-06-06 | 特瓦药物精化学品股份有限公司 | 阿托莫西汀盐酸盐的多形体 |
WO2006029253A2 (fr) * | 2004-09-04 | 2006-03-16 | Teva Pharmaceutical Industries Ltd. | Impurete de valacyclovir isolee, son procede de preparation et son utilisation comme standard de reference |
US20060081361A1 (en) * | 2004-09-13 | 2006-04-20 | Gabbey Lawrence W | Oil cooler with integral filter |
TWI321132B (en) * | 2004-09-28 | 2010-03-01 | Teva Pharma | Process for preparing forms of atorvastatin calcium substantially free of impurities |
WO2006045120A2 (fr) * | 2004-10-19 | 2006-04-27 | Teva Pharmaceutical Industries Ltd. | Purification du maleate de tegaserod |
US7678551B2 (en) * | 2004-10-25 | 2010-03-16 | Seradyn, Inc. | Immunoassays for lamotrigine |
US20060194869A1 (en) * | 2004-12-23 | 2006-08-31 | Santiago Ini | Process for preparing pharmaceutically acceptable salts of duloxetine and intermediates thereof |
MX2007007301A (es) * | 2005-01-11 | 2008-02-11 | Teva Pharm Fine Chemicals Srl | Polimorfos de clorhidrato de memantina. |
US20070167625A1 (en) * | 2005-02-22 | 2007-07-19 | Anna Balanov | Preparation of rosuvastatin |
KR100945763B1 (ko) | 2005-02-22 | 2010-03-08 | 테바 파마슈티컬 인더스트리즈 리미티드 | 로수바스타틴의 제조 방법 |
US20070037979A1 (en) * | 2005-02-22 | 2007-02-15 | Valerie Niddam-Hildesheim | Preparation of rosuvastatin |
CA2602073A1 (fr) * | 2005-02-24 | 2006-08-31 | Teva Pharmaceutical Industries Ltd. | Procedes de preparation d'intermediaire linezolid |
WO2006099433A1 (fr) * | 2005-03-14 | 2006-09-21 | Teva Pharmaceutical Industries Ltd. | Hydrochlorure de duloxetine pur |
US7569729B2 (en) * | 2005-04-05 | 2009-08-04 | Teva Pharmaceutical Fine Chemicals S.R.L. | Stable atomoxetine hydrochloride, a process for the preparation thereof, and an analytical control of its stability |
CN101160281A (zh) * | 2005-04-06 | 2008-04-09 | 特瓦制药工业有限公司 | 结晶形态的普瑞巴林 |
US7488846B2 (en) * | 2005-04-11 | 2009-02-10 | Teva Pharmaceuical Industries Ltd. | Pregabalin free of lactam and a process for preparation thereof |
WO2006110783A2 (fr) * | 2005-04-11 | 2006-10-19 | Teva Pharmaceutical Industries Ltd. | Procede de fabrication de (s)-pregabaline |
EP1869007A1 (fr) * | 2005-04-14 | 2007-12-26 | Teva Pharmaceutical Industries Ltd | Processus de preparation de fumarate de quetiapine |
US20080281111A1 (en) * | 2005-04-26 | 2008-11-13 | Sandor Molnar | Process for preparation of mycophenolate mofetil and other esters of mycophenolic acid |
WO2006121557A1 (fr) * | 2005-05-10 | 2006-11-16 | Teva Pharmaceutical Industries Ltd. | Pregabaline exempte de lactame et son procede de preparation |
ATE486841T1 (de) * | 2005-05-10 | 2010-11-15 | Teva Pharma | Verfahren zur herstellung von pregabalin und salzen daraus |
CA2604624A1 (fr) * | 2005-05-10 | 2006-11-16 | Teva Pharmaceutical Industries Ltd. | Resolution optique de l'acide 3-carbamoylmethyl-5-methyl hexanoique |
JP2008505980A (ja) * | 2005-05-10 | 2008-02-28 | テバ ファーマシューティカル インダストリーズ リミティド | イソブチルグルタル酸を有さないプレガバリン及びその調製方法 |
JP2008507565A (ja) | 2005-05-23 | 2008-03-13 | テバ ファーマシューティカル インダストリーズ リミティド | シナカルセトの精製 |
CN101233100A (zh) * | 2005-06-27 | 2008-07-30 | 西科尔公司 | 阿那曲唑中间体的杂质及其应用 |
US20070032660A1 (en) * | 2005-06-27 | 2007-02-08 | Alessandro Pontiroli | Purification process for Anastrozole intermediate |
CA2608369A1 (fr) * | 2005-07-05 | 2007-01-11 | Teva Pharmaceutical Industries Ltd. | Purification du montelukast |
TW200800917A (en) * | 2005-08-16 | 2008-01-01 | Teva Pharma | Crystalline rosuvastatin intermediate |
EP1841726B1 (fr) * | 2005-09-19 | 2012-10-31 | Teva Pharmaceutical Industries Ltd | Synthese asymetrique de l'acide (s)-(+)-3-(aminomethyl)-5-methylhexanoique |
US20070197529A1 (en) * | 2005-12-01 | 2007-08-23 | Viviana Braude | Isolated desfluoro-linezolid, preparation thereof and its use as a reference marker and standard |
WO2007067581A1 (fr) * | 2005-12-05 | 2007-06-14 | Teva Pharmaceutical Industries Ltd. | 2-(n-methyl-propanamine)-3-(2-naphtol)thiophene, une impurete du duloxetine chlorhydrate |
WO2007069264A2 (fr) * | 2005-12-15 | 2007-06-21 | Alembic Limited | Nouveaux composes |
WO2007076158A2 (fr) * | 2005-12-27 | 2007-07-05 | Teva Pharmaceutical Industries Ltd. | Procedes de preparation de bromhydrate de darifenacine |
CA2644819A1 (fr) * | 2006-03-27 | 2007-11-08 | Teva Pharmaceutical Fine Chemicals S.R.L. | Procede de synthese de chlorhydrate de memantine ne contenant essentiellement aucune impurete |
US20080146675A1 (en) * | 2006-04-05 | 2008-06-19 | Eugenio Castelli | Stable Atomoxetine Hydrochloride, a process for the preparation thereof, and an analytical control of its stability |
GB0609835D0 (en) * | 2006-05-18 | 2006-06-28 | Pliva Istrazivanje I Razvoj D | Impurities of a pharmaceutical product |
TW200815323A (en) * | 2006-05-24 | 2008-04-01 | Teva Pharma | Processes for the preparation of R-(+)-3-(carbamoylmethyl)-5-methylhexanoic acid and salts thereof |
WO2007143152A2 (fr) * | 2006-05-31 | 2007-12-13 | Teva Pharmaceutical Industries Ltd. | Préparation de (s)-prégabaline nitrile |
BRPI0702897A2 (pt) * | 2006-05-31 | 2011-03-15 | Teva Pharmaceutical Ind Ltda | processo para preparar um intermediário de pregabalina |
ES2339297T3 (es) * | 2006-06-29 | 2010-05-18 | Ivax Pharmaceuticals S.R.O. | Regulacion de la produccion de metabolitos acidos. |
US20120142919A1 (en) * | 2006-08-02 | 2012-06-07 | Medichem, S.A. | Method for synthesizing lamotrigine |
US20100087638A1 (en) * | 2006-08-14 | 2010-04-08 | Jean-Paul Roduit | Process for the preparation of lamotrigine |
EP2139845A1 (fr) * | 2007-02-26 | 2010-01-06 | Teva Pharmaceutical Industries Ltd. | Intermédiaires et procédés pour la synthèse de ramelteon |
BRPI0803092A2 (pt) * | 2007-03-22 | 2011-08-30 | Teva Pharma | sìntese de (s)-(+)-3-(aminometil)-5-metil ácido hexanóico, (s)-pregabalina |
TW200904982A (en) * | 2007-04-11 | 2009-02-01 | Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag | Method for reducing impurity level in mycophenolic acid fermentation |
EP2098519A1 (fr) * | 2007-05-31 | 2009-09-09 | Teva Pharmaceutical Industries Ltd. | Procédé de synthèse du rameltéon et ses intermédiaires |
US20090137842A1 (en) * | 2007-10-03 | 2009-05-28 | Vollerner Yuri | Pregabalin -4-eliminate, pregabalin 5-eliminate, their use as reference marker and standard, and method to produce pregabalin containing low levels thereof |
PL2508523T5 (pl) * | 2007-10-23 | 2020-08-10 | Teva Pharmaceutical Industries Ltd. | Odmiany polimorficzne dasatynibu i sposób ich wytwarzania |
US20090281176A1 (en) * | 2007-11-01 | 2009-11-12 | Vinod Kumar Kansal | Process for the synthesis of ramelteon and its intermediates |
US8486927B2 (en) * | 2007-11-09 | 2013-07-16 | Thar Pharmaceuticals | Crystalline forms of lamotrigine |
CA2717580A1 (fr) * | 2008-03-06 | 2009-12-17 | Teva Pharmaceutical Industries Ltd. | Procedes de preparation de la o-desmethylvenlafaxine, exempte de ses impuretes dimeres |
US20100087525A1 (en) * | 2008-06-23 | 2010-04-08 | Lilach Hedvati | Stereoselective enzymatic synthesis of (s) or (r)-iso-butyl-glutaric ester |
WO2010045565A1 (fr) * | 2008-10-16 | 2010-04-22 | Teva Pharmaceutical Industries Ltd. | Procédé de synthèse du ramelteon et de ses intermédiaires |
EP2539313A2 (fr) * | 2010-03-29 | 2013-01-02 | Pliva Hrvatska D.O.O. | Formes cristallines du fumarate de o-desméthylvenlafaxine |
WO2012034065A1 (fr) | 2010-09-09 | 2012-03-15 | Teva Pharmaceutical Industries Ltd. | Intermédiaires d'aliskirène et procédé destiné à analyser la pureté de l'aliskirène |
CN102766104A (zh) * | 2012-08-20 | 2012-11-07 | 三金集团湖南三金制药有限责任公司 | 一种治疗双向情感障碍及癫痫病药物拉莫三嗪的合成方法 |
US10189859B2 (en) | 2013-12-21 | 2019-01-29 | Nektar Therapeutics | Derivatives of 6-(2,3-dichlorophenyl)-1,2,4-triazin-5-amine |
CN110467560A (zh) | 2018-05-09 | 2019-11-19 | 深圳微芯生物科技股份有限公司 | 一种苯基氨基丙酸钠衍生物、其制备方法和应用 |
KR102270026B1 (ko) * | 2020-01-31 | 2021-06-28 | 현대약품 주식회사 | (3s)-3-(4-(3-(1,4-다이옥사스파이로[4,5]데스-7-엔-8-일)벤질옥시)페닐)헥스-4-이노익산의 품질 평가 방법 |
CN113156009B (zh) * | 2021-04-20 | 2023-12-22 | 三金集团湖南三金制药有限责任公司 | 高效液相色谱分析拉莫三嗪的方法 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996020934A1 (fr) * | 1994-12-30 | 1996-07-11 | The Wellcome Foundation Limited | Procede de preparation de lamotrigine |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU182086B (en) | 1979-06-01 | 1983-12-28 | Wellcome Found | Process for preparing new 1,2,4-triazine derivatives |
JPS5625170A (en) | 1979-06-01 | 1981-03-10 | Wellcome Found | Triazine derivative |
GB8613183D0 (en) | 1986-05-30 | 1986-07-02 | Wellcome Found | Triazine salt |
GB9426448D0 (en) * | 1994-12-30 | 1995-03-01 | Wellcome Found | Process |
GB9512854D0 (en) * | 1995-06-23 | 1995-08-23 | Wellcome Found | Novel formulation |
-
1998
- 1998-06-10 GB GBGB9812413.4A patent/GB9812413D0/en not_active Ceased
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1999
- 1999-02-24 EA EA199900159A patent/EA000666B1/ru not_active IP Right Cessation
- 1999-02-25 SG SG9901252A patent/SG85628A1/en unknown
- 1999-03-09 KR KR1019990007632A patent/KR100322354B1/ko active IP Right Review Request
- 1999-03-09 HR HR990074A patent/HRP990074A2/hr not_active Application Discontinuation
- 1999-03-10 PT PT99200695T patent/PT963980E/pt unknown
- 1999-03-10 TR TR1999/00520A patent/TR199900520A3/tr unknown
- 1999-03-10 DK DK99200695T patent/DK0963980T3/da active
- 1999-03-10 PL PL99331870A patent/PL331870A1/xx not_active Application Discontinuation
- 1999-03-10 CA CA002265194A patent/CA2265194C/fr not_active Expired - Fee Related
- 1999-03-10 PE PE1999000190A patent/PE20000332A1/es not_active Application Discontinuation
- 1999-03-10 ZA ZA9901951A patent/ZA991951B/xx unknown
- 1999-03-10 ES ES99200695T patent/ES2178342T3/es not_active Expired - Lifetime
- 1999-03-10 AR ARP990101018A patent/AR014074A1/es not_active Application Discontinuation
- 1999-03-10 SI SI9930088T patent/SI0963980T1/xx unknown
- 1999-03-10 JP JP11063792A patent/JP2989189B1/ja not_active Expired - Fee Related
- 1999-03-10 BR BR9900984-6A patent/BR9900984A/pt not_active IP Right Cessation
- 1999-03-10 HU HU9900592A patent/HUP9900592A3/hu unknown
- 1999-03-10 DE DE69901656T patent/DE69901656T2/de not_active Expired - Fee Related
- 1999-03-10 MA MA25489A patent/MA24777A1/fr unknown
- 1999-03-10 NO NO991151A patent/NO991151L/no unknown
- 1999-03-10 CN CN99103445A patent/CN1238454A/zh active Pending
- 1999-03-10 ID IDP990201D patent/ID22957A/id unknown
- 1999-03-10 NZ NZ334590A patent/NZ334590A/xx unknown
- 1999-03-10 EP EP01203376A patent/EP1170588A1/fr not_active Withdrawn
- 1999-03-10 US US09/265,670 patent/US6333198B1/en not_active Expired - Fee Related
- 1999-03-10 YU YU12399A patent/YU12399A/sh unknown
- 1999-03-10 AU AU20319/99A patent/AU2031999A/en not_active Abandoned
- 1999-03-10 AP APAP/P/1999/001481A patent/AP9901481A0/en unknown
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- 1999-03-10 AP APAP/P/2001/002286A patent/AP0102286A0/en unknown
- 1999-03-10 EP EP99200695A patent/EP0963980B1/fr not_active Expired - Lifetime
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2000
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2001
- 2001-09-06 AP AP2001002286A patent/AP2001002286A0/xx unknown
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2003
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Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996020934A1 (fr) * | 1994-12-30 | 1996-07-11 | The Wellcome Foundation Limited | Procede de preparation de lamotrigine |
Non-Patent Citations (1)
Title |
---|
SAILSTAD J.M. & FINDLAY J.W.A.: "Immunofluorometric assay for lamotrigine (Lamictal) in human plasma" THERAPEUTIC DRUG MONITORING, US, RAVEN PRESS, NEW YORK, NY, vol. 13, no. 5, September 1991 (1991-09), pages 433-442, XP000882274 * |
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