US5476932A
(en)
*
|
1994-08-26 |
1995-12-19 |
Hoffmann-La Roche Inc. |
Process for producing N4-acyl-5'-deoxy-5-fluorocytidine derivatives
|
EP0882734B1
(en)
*
|
1997-06-02 |
2009-08-26 |
F. Hoffmann-La Roche Ag |
5'-Deoxy-cytidine derivatives
|
NZ330360A
(en)
*
|
1997-06-02 |
1999-03-29 |
Hoffmann La Roche |
5'-deoxy-cytidine derivatives, their manufacture and use as antitumoral agents
|
US6005098A
(en)
*
|
1998-02-06 |
1999-12-21 |
Hoffmann-La Roche Inc. |
5'deoxycytidine derivatives
|
ES2185378T3
(es)
*
|
1998-09-25 |
2003-04-16 |
Warner Lambert Co |
Quimioterapia de cancer con acetildinalina en combinacion con gemcitabina, capecitabina o cisplatina.
|
US20080113025A1
(en)
*
|
1998-11-02 |
2008-05-15 |
Elan Pharma International Limited |
Compositions comprising nanoparticulate naproxen and controlled release hydrocodone
|
US20070122481A1
(en)
*
|
1998-11-02 |
2007-05-31 |
Elan Corporation Plc |
Modified Release Compositions Comprising a Fluorocytidine Derivative for the Treatment of Cancer
|
ES2273841T3
(es)
|
2000-02-28 |
2007-05-16 |
Pfizer Enterprises Sarl |
Combinacion sinergica para el tratamiento de cancer colorrectal.
|
AU2001246863A1
(en)
*
|
2000-04-11 |
2001-10-23 |
Sayuri Yamada |
Curcumin compositions
|
KR100730768B1
(ko)
*
|
2000-08-09 |
2007-06-21 |
코오롱생명과학 주식회사 |
5'-데옥시-n-알킬옥시카르보닐-5-플루오로사이토신-5'-카르복실산 및 그 유도체와 이들의 제조방법
|
KR100631754B1
(ko)
*
|
2000-08-09 |
2006-10-09 |
주식회사 코오롱 |
N-알킬옥시카르보닐-5-플루오로사이토신 유도체 및 그의제조방법
|
WO2003079972A2
(en)
|
2002-02-22 |
2003-10-02 |
New River Parmaceuticals Inc. |
Active agent delivery systems and methods for protecting and administering active agents
|
GB0113374D0
(en)
*
|
2001-06-04 |
2001-07-25 |
Jerram Clare |
Washing line umbrella
|
AU2003235761A1
(en)
*
|
2002-01-14 |
2003-07-24 |
Novartis Ag |
Combinations comprising epothilones and anti-metabolites
|
BR0316238A
(pt)
*
|
2002-11-15 |
2005-10-11 |
Warner Lambert Co |
Quimioterapia de associação compreendendo um inibidor de mek e capecitabina para tratamento de câncer
|
AU2003233586A1
(en)
*
|
2003-05-20 |
2005-01-21 |
Aronex Pharmaceuticals, Inc. |
Combination chemotherapy comprising capecitabine and a liposomal platinum complex
|
EP1689404B9
(en)
*
|
2003-11-13 |
2009-04-22 |
Pharma Mar, S.A.U. |
Combination of et-743 with 5-fluorouracil pro-drugs for the treatment of cancer
|
CA2550299C
(en)
*
|
2003-12-22 |
2010-03-30 |
Christopher R. Roberts |
Process for fluorocytidine derivatives
|
WO2006084058A2
(en)
|
2005-02-03 |
2006-08-10 |
The General Hospital Corporation |
Method for treating gefitinib resistant cancer
|
WO2006103187A2
(en)
*
|
2005-04-01 |
2006-10-05 |
F. Hoffmann-La Roche Ag |
Method for administration of capecitabine
|
ZA200800907B
(en)
|
2005-07-18 |
2010-04-28 |
Bipar Sciences Inc |
Treatment of cancer
|
ES2384267T3
(es)
|
2005-07-21 |
2012-07-03 |
Nuvo Research Ag |
Soluciones de clorito estabilizadas en combinación con fluoropirimidinas para el tratamiento del cáncer
|
WO2007056118A1
(en)
|
2005-11-04 |
2007-05-18 |
Wyeth |
Antineoplastic combinations with mtor inhibitor, herceptin, and/or hki-272
|
HUE030235T2
(en)
|
2005-12-13 |
2017-04-28 |
Incyte Holdings Corp |
Heteroaryl-substituted pyrrolo [2,3-b] pyridines and pyrrolo [2,3-b] pyrimidines as Janus kinase inhibitors
|
US20100160442A1
(en)
*
|
2006-07-18 |
2010-06-24 |
Ossovskaya Valeria S |
Formulations for cancer treatment
|
US20080085310A1
(en)
*
|
2006-10-06 |
2008-04-10 |
Maria Oksana Bachynsky |
Capecitabine rapidly disintegrating tablets
|
CN100425617C
(zh)
*
|
2006-10-31 |
2008-10-15 |
浙江海正药业股份有限公司 |
一种含氟嘧啶类化合物烷氧羰酰化的方法
|
ITMI20070435A1
(it)
|
2007-03-05 |
2008-09-06 |
Innovate Biotechnology Srl |
2',3'-di-o-acil-5-fluoronucleosidi
|
EP2137201A2
(en)
*
|
2007-04-20 |
2009-12-30 |
Dr. Reddy's Laboratories Ltd. |
Process for preparing capecitabine
|
EP2164856A1
(en)
*
|
2007-06-01 |
2010-03-24 |
Synthon B.V. |
Processes related to making capecitabine
|
EP3070090B1
(en)
|
2007-06-13 |
2018-12-12 |
Incyte Holdings Corporation |
Use of salts of the janus kinase inhibitor (r)-3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h- pyrazol-1-yl)-3- cyclopentylpropanenitrile
|
US7842675B2
(en)
*
|
2007-09-15 |
2010-11-30 |
Protia, Llc |
Deuterium-enriched capecitabine
|
WO2009042064A2
(en)
|
2007-09-21 |
2009-04-02 |
Nektar Therapeutics Al, Corporation |
Oligomer-nucleoside phosphate conjugates
|
US8022216B2
(en)
|
2007-10-17 |
2011-09-20 |
Wyeth Llc |
Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof
|
KR101013312B1
(ko)
*
|
2007-11-19 |
2011-02-09 |
한미홀딩스 주식회사 |
카페시타빈의 제조방법 및 이에 사용되는 β-아노머가강화된 트리알킬카보네이트 화합물의 제조방법
|
AR064165A1
(es)
|
2007-12-06 |
2009-03-18 |
Richmond Sa Com Ind Y Financie |
Un procedimiento para la preparacion de capecitabina e intermediarios utilizables en dicho procedimiento
|
US20090209754A1
(en)
*
|
2008-01-03 |
2009-08-20 |
Macdonald Peter Lindsay |
Process for the preparation of capecitabine
|
US20090311335A1
(en)
*
|
2008-06-12 |
2009-12-17 |
Scott Jenkins |
Combination of a triptan and an nsaid
|
EP2915532B1
(en)
|
2008-06-17 |
2016-10-19 |
Wyeth LLC |
Antineoplastic combinations containing hki-272 and vinorelbine
|
ES2614912T3
(es)
|
2008-08-04 |
2017-06-02 |
Wyeth Llc |
Combinaciones antineoplásicas de 4-anilino-3-cianoquinolinas y capecitabina
|
WO2010065586A2
(en)
*
|
2008-12-02 |
2010-06-10 |
Dr. Reddy's Laboratories Ltd. |
Preparation of capecitabine
|
US8603999B2
(en)
|
2008-12-05 |
2013-12-10 |
Commonwealth Scientific And Industrial Research Organisation |
Amphiphile prodrugs
|
EP3000467B1
(en)
|
2009-04-06 |
2023-03-01 |
Wyeth LLC |
Treatment regimen utilizing neratinib for breast cancer
|
FR2945211A1
(fr)
|
2009-05-06 |
2010-11-12 |
Sanofi Aventis |
Combinaison antitumorale comprenant la cabazitaxel et la capecitabine
|
EA020494B1
(ru)
|
2009-05-22 |
2014-11-28 |
Инсайт Корпорейшн |
3-[4-(7H-ПИРРОЛО[2,3-d]ПИРИМИДИН-4-ИЛ)-1H-ПИРАЗОЛ-1-ИЛ]ОКТАН- ИЛИ ГЕПТАННИТРИЛ КАК JAK-ИНГИБИТОРЫ
|
WO2011010967A1
(en)
*
|
2009-07-23 |
2011-01-27 |
Scinopharm Taiwan Ltd. |
Process for producing flurocytidine derivatives
|
WO2011067588A1
(en)
|
2009-12-04 |
2011-06-09 |
Generics [Uk] Limited |
Cyclic sulphinyl esters of cytidine
|
WO2011104540A1
(en)
*
|
2010-02-24 |
2011-09-01 |
Generics [Uk] Limited |
One step process for the preparation of capecitabine
|
MX347851B
(es)
|
2010-03-10 |
2017-05-16 |
Incyte Corp |
Derivados de piperidin-4-il azetidina como inhibidores de janus cinasa 1 (jak1).
|
HUE040107T2
(hu)
|
2010-03-12 |
2019-02-28 |
Genzyme Corp |
Kombinációs terápia mellrák kezelésére
|
EP3087972A1
(en)
|
2010-05-21 |
2016-11-02 |
Incyte Holdings Corporation |
Topical formulation for a jak inhibitor
|
CN102260309B
(zh)
*
|
2010-05-24 |
2014-10-22 |
重庆福安药业(集团)股份有限公司 |
一种高纯度卡培他滨的制备方法
|
SG190839A1
(en)
|
2010-11-19 |
2013-07-31 |
Incyte Corp |
Cyclobutyl substituted pyrrolopyridine and pyrrolopyrimidine derivatives as jak inhibitors
|
CN102558262A
(zh)
*
|
2010-12-23 |
2012-07-11 |
天津泰普药品科技发展有限公司 |
一种高纯度卡培他滨的制备方法
|
AR086983A1
(es)
|
2011-06-20 |
2014-02-05 |
Incyte Corp |
Derivados de azetidinil fenil, piridil o pirazinil carboxamida como inhibidores de jak
|
CN102266303A
(zh)
*
|
2011-07-07 |
2011-12-07 |
程雪翔 |
一种卡培他滨药用组合物及其制备方法
|
UA111854C2
(uk)
|
2011-09-07 |
2016-06-24 |
Інсайт Холдінгс Корпорейшн |
Способи і проміжні сполуки для отримання інгібіторів jak
|
CN102516338B
(zh)
*
|
2011-12-09 |
2014-04-02 |
海南锦瑞制药股份有限公司 |
一种卡培他滨化合物、其药物组合物及其制备方法
|
TWI560195B
(en)
*
|
2012-01-13 |
2016-12-01 |
Pharmaessentia Corp |
Novel synthesis of 5-deoxy-5'-fluorocytidine compounds
|
KR20220162825A
(ko)
|
2012-11-15 |
2022-12-08 |
인사이트 홀딩스 코포레이션 |
룩솔리티니브의 서방성 제형
|
AU2014225938B2
(en)
|
2013-03-06 |
2018-07-19 |
Incyte Holdings Corporation |
Processes and intermediates for making a JAK inhibitor
|
KR20160045081A
(ko)
|
2013-08-07 |
2016-04-26 |
인사이트 코포레이션 |
Jak1 억제제용 지속 방출 복용 형태
|
SG11201601119XA
(en)
*
|
2013-08-20 |
2016-03-30 |
Incyte Corp |
Survival benefit in patients with solid tumors with elevated c-reactive protein levels
|
EP2883959A1
(en)
|
2013-12-13 |
2015-06-17 |
Plasmia Biotech, S.L. |
Enzymatic production of cytosinic nucleoside analogues
|
CN103897006A
(zh)
*
|
2013-12-18 |
2014-07-02 |
吉林修正药业新药开发有限公司 |
一种卡培他滨异构体的制备方法
|
US10080807B2
(en)
|
2014-06-09 |
2018-09-25 |
Lipomedix Pharmaceuticals Ltd. |
Combination chemotherapy comprising a liposomal prodrug of mitomycin C
|
CN104530164A
(zh)
*
|
2014-12-31 |
2015-04-22 |
辰欣药业股份有限公司 |
一种卡培他滨的合成工艺
|
KR20160117060A
(ko)
|
2015-03-31 |
2016-10-10 |
이승주 |
유아용 탁자
|
CN105646625B
(zh)
*
|
2015-12-29 |
2019-06-11 |
江苏吴中医药集团有限公司 |
一种卡培他滨的制备方法
|
WO2018129533A1
(en)
|
2017-01-09 |
2018-07-12 |
Shuttle Pharmaceuticals, Llc |
Selective histone deacetylase inhibitors for the treatment of human disease
|
US11584733B2
(en)
|
2017-01-09 |
2023-02-21 |
Shuttle Pharmaceuticals, Inc. |
Selective histone deacetylase inhibitors for the treatment of human disease
|
TR201702500A2
(tr)
*
|
2017-02-20 |
2017-07-21 |
Anadolu Ueniversitesi |
Serani̇b-2?ni̇n akci̇ğer kanseri̇ ve meme kanseri̇ni̇n tedavi̇si̇nde kullanimi
|
US10435429B2
(en)
|
2017-10-03 |
2019-10-08 |
Nucorion Pharmaceuticals, Inc. |
5-fluorouridine monophosphate cyclic triester compounds
|
TW201924683A
(zh)
|
2017-12-08 |
2019-07-01 |
美商英塞特公司 |
用於治療骨髓增生性贅瘤的低劑量組合療法
|
EP3737376B1
(en)
|
2018-01-09 |
2024-04-17 |
Shuttle Pharmaceuticals, Inc. |
Selective histone deacetylase inhibitors for the treatment of human diseases
|
CN111801339A
(zh)
*
|
2018-01-19 |
2020-10-20 |
纽科利制药公司 |
5-氟尿嘧啶化合物
|
US11427550B2
(en)
|
2018-01-19 |
2022-08-30 |
Nucorion Pharmaceuticals, Inc. |
5-fluorouracil compounds
|
TWI797242B
(zh)
|
2018-01-30 |
2023-04-01 |
美商英塞特公司 |
製備jak抑制劑之方法及中間物
|
MX2022012285A
(es)
|
2018-03-30 |
2023-08-15 |
Incyte Corp |
Tratamiento de la hidradenitis supurativa mediante el uso de inhibidores de actividad de la cinasa janus (jak).
|
JP2022517352A
(ja)
|
2019-01-11 |
2022-03-08 |
リポメディックス・ファーマシューティカルズ・リミテッド |
マイトマイシンcのリポソーム化プロドラッグを含むリポソーム組成物および製造法
|
JP2023523415A
(ja)
|
2020-04-21 |
2023-06-05 |
リガンド・ファーマシューティカルズ・インコーポレイテッド |
ヌクレオチドプロドラッグ化合物
|
US11833155B2
(en)
|
2020-06-03 |
2023-12-05 |
Incyte Corporation |
Combination therapy for treatment of myeloproliferative neoplasms
|
WO2023177894A1
(en)
|
2022-03-18 |
2023-09-21 |
Ideaya Biosciences, Inc. |
Combination therapy comprising a mat2a inhibitor and an antimetabolite agent
|