ZA825513B - New derivatives of pyridazine active on the central nervous system - Google Patents

New derivatives of pyridazine active on the central nervous system

Info

Publication number
ZA825513B
ZA825513B ZA825513A ZA825513A ZA825513B ZA 825513 B ZA825513 B ZA 825513B ZA 825513 A ZA825513 A ZA 825513A ZA 825513 A ZA825513 A ZA 825513A ZA 825513 B ZA825513 B ZA 825513B
Authority
ZA
South Africa
Prior art keywords
pyridazine
active
nervous system
central nervous
new derivatives
Prior art date
Application number
ZA825513A
Other languages
English (en)
Inventor
Jean-Paul Kan
Kathleen Biziere
Camille Georges Wermuth
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of ZA825513B publication Critical patent/ZA825513B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
ZA825513A 1981-08-07 1982-07-30 New derivatives of pyridazine active on the central nervous system ZA825513B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8115380A FR2510998B1 (fr) 1981-08-07 1981-08-07 Nouveaux derives amines de la pyridazine, leur procede de preparation et les medicaments, a action desinhibitrice, qui en comportent

Publications (1)

Publication Number Publication Date
ZA825513B true ZA825513B (en) 1983-06-29

Family

ID=9261294

Family Applications (2)

Application Number Title Priority Date Filing Date
ZA825513A ZA825513B (en) 1981-08-07 1982-07-30 New derivatives of pyridazine active on the central nervous system
ZA825512A ZA825512B (en) 1981-08-07 1982-07-30 New amino compounds derived from pyridazine,active on the central nervous system

Family Applications After (1)

Application Number Title Priority Date Filing Date
ZA825512A ZA825512B (en) 1981-08-07 1982-07-30 New amino compounds derived from pyridazine,active on the central nervous system

Country Status (30)

Country Link
US (1) US4508720A (no)
EP (2) EP0074863B1 (no)
JP (2) JPS5877868A (no)
KR (2) KR880001624B1 (no)
AR (2) AR231441A1 (no)
AT (2) ATE12227T1 (no)
AU (2) AU548930B2 (no)
CA (2) CA1174240A (no)
CS (2) CS229941B2 (no)
DD (2) DD202715A5 (no)
DE (2) DE3262671D1 (no)
DK (2) DK148795C (no)
EG (2) EG15747A (no)
ES (2) ES514795A0 (no)
FI (2) FI72968C (no)
FR (1) FR2510998B1 (no)
GR (2) GR76430B (no)
HU (2) HU190028B (no)
IE (2) IE53388B1 (no)
IL (2) IL66408A (no)
MA (2) MA19562A1 (no)
NO (2) NO157861C (no)
NZ (2) NZ201518A (no)
OA (2) OA07175A (no)
PH (1) PH18545A (no)
PL (2) PL130647B1 (no)
PT (2) PT75350B (no)
SU (2) SU1138024A3 (no)
YU (2) YU172082A (no)
ZA (2) ZA825513B (no)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2540113A1 (fr) * 1983-01-27 1984-08-03 Sanofi Sa Acides derives de la pyridazine actifs sur le systeme nerveux central
US4565814A (en) * 1983-01-28 1986-01-21 Sanofi Pyridazine derivatives having a psychotropic action and compositions
US4628088A (en) * 1984-07-17 1986-12-09 Eli Lilly And Company Preparation of substituted pyridazines
EP0190563B1 (de) * 1985-01-14 1989-08-02 Boehringer Ingelheim Kg Neue 12-Amino-pyridazino[4',5':3,4]pyrrolo-[2,1-a]isochinoline, Verfahren zu ihrer Herstellung und ihre Verwendung
US5631255A (en) * 1989-02-07 1997-05-20 Sanofi Pyridazine derivatives
PT93060B (pt) 1989-02-07 1995-12-29 Sanofi Sa Processo para a obtencao de derivados de piridazina e de composicoes farmaceuticas que os contem
FR2642648B1 (fr) * 1989-02-07 1991-06-21 Sanofi Sa Utilisation de derives d'alkyl-5 pyridazine comme medicaments actifs sur le systeme cholinergique
FR2663326B2 (fr) * 1989-11-17 1992-10-16 Sanofi Sa Derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant.
FR2654727B1 (fr) * 1989-11-17 1992-03-27 Sanofi Sa Derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant.
FR2642754B1 (fr) * 1989-02-07 1991-05-24 Sanofi Sa Nouveaux derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant
FR2665442B1 (fr) * 1990-07-31 1992-12-04 Sanofi Sa Derives d'alkyl-6 pyridazine, procede de preparation et compositions pharmaceutiques en contenant.
US5461053A (en) * 1989-02-07 1995-10-24 Sanofi Pyridazine derivatives
FR2676444B1 (fr) * 1991-05-16 1995-03-10 Sanofi Elf Nouveaux derives d'amino-3 pyridazines actifs sur le systeme nerveux central, procede de preparation et compositions pharmaceutiques en contenant.
US20100210590A1 (en) * 1995-09-27 2010-08-19 Northwestern University Compositions and treatments for seizure-related disorders
US20030176437A1 (en) * 2001-08-31 2003-09-18 D.M. Watterson Anti-inflammatory and protein kinase inhibitor compositions and related methods for downregulation of detrimental cellular responses and inhibition of cell death
EP1532120B1 (en) * 2002-08-13 2009-01-14 MERCK SHARP & DOHME LTD. Phenylpyridazine derivatives as ligands for gaba receptors
JP2008518955A (ja) * 2004-11-02 2008-06-05 ノースウェスタン ユニバーシティ ピリダジン化合物および方法
EP2592075B1 (en) * 2004-11-02 2015-04-29 Northwestern University Pyridazine compounds for the treatment of inflammatory diseases
EP2063894B1 (en) * 2006-04-28 2019-08-28 Northwestern University Formulations containing pyridazine compounds for treating neuroinflammatory diseases
US20100168120A1 (en) * 2006-04-28 2010-07-01 Neuromedix Inc. Salts of pyridazine compounds
WO2007127474A2 (en) * 2006-04-28 2007-11-08 Northwestern University Compositions and treatments using pyridazine compounds and cholinesterase inhibitors
RU2555969C1 (ru) * 2014-07-09 2015-07-10 Юлия Алексеевна Щепочкина Керамическая масса для изготовления облицовочной плитки

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1345880A (en) * 1971-06-18 1974-02-06 Cepbepe Pyridazine derivatives

Also Published As

Publication number Publication date
DK354382A (da) 1983-02-08
FI72969C (fi) 1987-08-10
JPS5877867A (ja) 1983-05-11
GR76429B (no) 1984-08-10
IL66409A (en) 1985-09-29
FR2510998B1 (fr) 1986-01-10
FI72969B (fi) 1987-04-30
DE3269383D1 (en) 1986-04-03
EG15788A (en) 1986-09-30
PL137199B1 (en) 1986-05-31
AU8655482A (en) 1983-02-10
EP0074863B1 (fr) 1986-02-26
EP0074863A1 (fr) 1983-03-23
FI72968B (fi) 1987-04-30
HU189166B (en) 1986-06-30
DK148795C (da) 1986-03-10
ATE18216T1 (de) 1986-03-15
NO157102B (no) 1987-10-12
KR890001569B1 (ko) 1989-05-08
ZA825512B (en) 1983-06-29
PL130647B1 (en) 1984-08-31
AU8655382A (en) 1983-02-10
DK148795B (da) 1985-09-30
PT75351A (fr) 1982-08-01
KR840001145A (ko) 1984-03-28
NZ201518A (en) 1985-04-30
CS229941B2 (en) 1984-07-16
CA1179346A (en) 1984-12-11
US4508720A (en) 1985-04-02
SU1138024A3 (ru) 1985-01-30
KR840001159A (ko) 1984-03-28
FI822748A0 (fi) 1982-08-06
DD202715A5 (de) 1983-09-28
PH18545A (en) 1985-08-09
IE53387B1 (en) 1988-10-26
DK148537B (da) 1985-07-29
IE821779L (en) 1983-02-07
EP0072726A1 (fr) 1983-02-23
DK148537C (da) 1986-01-13
ATE12227T1 (de) 1985-04-15
IL66408A (en) 1985-12-31
IL66408A0 (en) 1982-11-30
OA07176A (fr) 1984-04-30
ES8305737A1 (es) 1983-04-16
FI72968C (fi) 1987-08-10
JPH0459312B2 (no) 1992-09-21
FI822747A0 (fi) 1982-08-06
CS229940B2 (en) 1984-07-16
NO157102C (no) 1988-01-20
YU171882A (en) 1985-03-20
PT75350B (fr) 1984-08-01
DD202549A5 (de) 1983-09-21
PT75350A (fr) 1982-08-01
OA07175A (fr) 1984-04-30
AU548931B2 (en) 1986-01-09
AR231441A1 (es) 1984-11-30
KR880001624B1 (ko) 1988-09-02
EP0072726B1 (fr) 1985-03-20
FI822747L (fi) 1983-02-08
NO822509L (no) 1983-02-08
CA1174240A (en) 1984-09-11
AR231637A1 (es) 1985-01-31
PL237808A1 (en) 1983-02-28
MA19562A1 (fr) 1983-04-01
DK354482A (da) 1983-02-08
ES8305738A1 (es) 1983-04-16
SU1140685A3 (ru) 1985-02-15
FR2510998A1 (fr) 1983-02-11
YU172082A (en) 1985-03-20
IE821778L (en) 1983-02-07
DE3262671D1 (en) 1985-04-25
NZ201520A (en) 1985-04-30
EG15747A (en) 1986-06-30
NO157861C (no) 1988-06-01
IL66409A0 (en) 1982-11-30
FI822748L (fi) 1983-02-08
ES514794A0 (es) 1983-04-16
HU190028B (en) 1986-08-28
JPS5877868A (ja) 1983-05-11
MA19560A1 (fr) 1983-04-01
NO157861B (no) 1988-02-22
NO822510L (no) 1983-02-08
IE53388B1 (en) 1988-10-26
PL237809A1 (en) 1983-02-28
AU548930B2 (en) 1986-01-09
GR76430B (no) 1984-08-10
PT75351B (fr) 1984-08-01
ES514795A0 (es) 1983-04-16

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