ZA200809003B - Nasolacrimal drainage system implants for drug therapy - Google Patents
Nasolacrimal drainage system implants for drug therapyInfo
- Publication number
- ZA200809003B ZA200809003B ZA200809003A ZA200809003A ZA200809003B ZA 200809003 B ZA200809003 B ZA 200809003B ZA 200809003 A ZA200809003 A ZA 200809003A ZA 200809003 A ZA200809003 A ZA 200809003A ZA 200809003 B ZA200809003 B ZA 200809003B
- Authority
- ZA
- South Africa
- Prior art keywords
- drainage system
- drug therapy
- nasolacrimal drainage
- system implants
- implants
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0026—Ophthalmic product dispenser attachments to facilitate positioning near the eye
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/00772—Apparatus for restoration of tear ducts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/00781—Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
- A61K9/0017—Non-human animal skin, e.g. pour-on, spot-on
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2220/0008—Fixation appliances for connecting prostheses to the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0085—Identification means; Administration of patients
- A61F2250/0087—Identification means; Administration of patients colour-coded
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US78777506P | 2006-03-31 | 2006-03-31 | |
US87186406P | 2006-12-26 | 2006-12-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200809003B true ZA200809003B (en) | 2009-10-28 |
Family
ID=38564290
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200808401A ZA200808401B (en) | 2006-03-31 | 2008-10-02 | Drug delivery methods, structures, and compositions for nasolacrimal system |
ZA200809003A ZA200809003B (en) | 2006-03-31 | 2008-10-21 | Nasolacrimal drainage system implants for drug therapy |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200808401A ZA200808401B (en) | 2006-03-31 | 2008-10-02 | Drug delivery methods, structures, and compositions for nasolacrimal system |
Country Status (19)
Country | Link |
---|---|
US (17) | US7998497B2 (xx) |
EP (3) | EP2010096B1 (xx) |
JP (10) | JP5208916B2 (xx) |
KR (4) | KR101270113B1 (xx) |
CN (2) | CN103393496B (xx) |
AU (2) | AU2007234445B2 (xx) |
BR (2) | BRPI0709663A2 (xx) |
CA (2) | CA2648421C (xx) |
DK (2) | DK2010096T3 (xx) |
ES (2) | ES2640458T3 (xx) |
HK (2) | HK1190909A1 (xx) |
IL (5) | IL194514A0 (xx) |
MX (2) | MX2008012601A (xx) |
NO (2) | NO20084275L (xx) |
NZ (4) | NZ572193A (xx) |
RU (4) | RU2414199C2 (xx) |
SG (2) | SG170816A1 (xx) |
WO (2) | WO2007115261A2 (xx) |
ZA (2) | ZA200808401B (xx) |
Families Citing this family (167)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9808052D0 (en) | 1998-04-17 | 1998-06-17 | Secr Defence | Implants for administering substances and methods of producing implants |
US7431710B2 (en) | 2002-04-08 | 2008-10-07 | Glaukos Corporation | Ocular implants with anchors and methods thereof |
US20040225250A1 (en) | 2003-05-05 | 2004-11-11 | Michael Yablonski | Internal shunt and method for treating glaucoma |
US7291125B2 (en) | 2003-11-14 | 2007-11-06 | Transcend Medical, Inc. | Ocular pressure regulation |
US20050232972A1 (en) * | 2004-04-15 | 2005-10-20 | Steven Odrich | Drug delivery via punctal plug |
JP2008504938A (ja) | 2004-07-02 | 2008-02-21 | レイザー,エリオット | 治療媒体送出装置およびその送出装置を用いて治療媒体を眼に送り出す方法 |
EP2594259A1 (en) | 2004-08-04 | 2013-05-22 | Brookwood Pharmaceuticals, Inc. | Methods for manufacturing delivery devices and devices thereof |
EP1933810B1 (en) | 2005-08-11 | 2012-10-10 | Massachusetts Institute of Technology | Intravesical drug delivery device and method |
CA2621303A1 (en) * | 2005-09-01 | 2007-03-08 | Bristol-Myers Squibb Company | Biomarkers and methods for determining sensitivity to vascular endothelial growth factor receptor-2 modulators |
US20070212397A1 (en) * | 2005-09-15 | 2007-09-13 | Roth Daniel B | Pharmaceutical delivery device and method for providing ocular treatment |
CN101437571B (zh) | 2005-10-13 | 2013-01-02 | 斯恩蒂斯有限公司 | 载药包装物 |
ES2653845T3 (es) | 2006-01-17 | 2018-02-09 | Novartis Ag | Dispositivo de tratamiento de administración de fármaco |
AU2006336598B2 (en) | 2006-01-17 | 2013-10-10 | Alcon Inc. | Glaucoma treatment device |
ATE497797T1 (de) | 2006-03-14 | 2011-02-15 | Univ Southern California | Mems-vorrichtung zur wirkstofffreisetzung |
DK2010096T3 (en) | 2006-03-31 | 2017-10-02 | Mati Therapeutics Inc | NASOLACRIMAL DRAINAGE SYSTEM IMPLANTS FOR PHARMACEUTICAL THERAPY |
US9474645B2 (en) * | 2006-06-21 | 2016-10-25 | Johnson & Johnson Vision Care, Inc. | Punctal plugs for the delivery of active agents |
CN101505696B (zh) * | 2006-06-21 | 2012-11-14 | 庄臣及庄臣视力保护公司 | 用于递送活性试剂的泪点塞 |
KR101409436B1 (ko) * | 2006-11-09 | 2014-06-24 | 알콘 리서치, 리미티드 | 수불용성 폴리머 매트릭스를 포함하는 누점마개 |
PL2091514T3 (pl) | 2006-11-09 | 2014-03-31 | Alcon Res Ltd | Nierozpuszczalna w wodzie matryca polimerowa do dostarczania leku |
UY30883A1 (es) * | 2007-01-31 | 2008-05-31 | Alcon Res | Tapones punctales y metodos de liberacion de agentes terapeuticos |
US8672870B2 (en) | 2007-07-17 | 2014-03-18 | Transcend Medical, Inc. | Ocular implant with hydrogel expansion capabilities |
WO2009035562A2 (en) * | 2007-09-07 | 2009-03-19 | Qlt Plug Delivery, Inc | Drug cores for sustained release of therapeutic agents |
CN101969897A (zh) * | 2007-09-07 | 2011-02-09 | Qlt栓塞输送公司 | 用于泪腺植入物的插入和抽出工具 |
CA2698508C (en) | 2007-09-07 | 2017-06-06 | Alan R. Rapacki | Lacrimal implants and related methods |
AU2008300022A1 (en) | 2007-09-07 | 2009-03-19 | Qlt Inc. | Lacrimal implant detection |
CA2705239C (en) | 2007-11-08 | 2018-09-25 | Alimera Sciences, Inc. | Ocular implantation device |
CA2706384C (en) | 2007-12-11 | 2016-05-31 | Massachusetts Institute Of Technology | Implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens |
US20100310622A1 (en) * | 2007-12-17 | 2010-12-09 | University Of Florida Research Foundation, Inc. | Dry eye treatment by puncta plugs |
US9308124B2 (en) * | 2007-12-20 | 2016-04-12 | University Of Southern California | Apparatus and methods for delivering therapeutic agents |
CA2709712C (en) | 2007-12-20 | 2016-05-10 | Surmodics Pharmaceuticals, Inc. | Process for preparing microparticles having a low residual solvent volume |
JP5528356B2 (ja) * | 2008-02-18 | 2014-06-25 | キュー エル ティー インク. | 涙管インプラントおよび関連する方法 |
CN104623741A (zh) * | 2008-04-30 | 2015-05-20 | 马缇医疗股份有限公司 | 复合泪管植入物及相关方法 |
CN102202719B (zh) | 2008-05-08 | 2014-11-26 | 迷你泵有限责任公司 | 可植入泵和用于可植入泵的插管 |
US9849238B2 (en) | 2008-05-08 | 2017-12-26 | Minipumps, Llc | Drug-delivery pump with intelligent control |
EP2323716B1 (en) | 2008-05-08 | 2015-03-04 | MiniPumps, LLC | Drug-delivery pumps |
AU2009244804A1 (en) * | 2008-05-09 | 2009-11-12 | Qlt Inc. | Sustained release delivery of active agents to treat glaucoma and ocular hypertension |
TW201012469A (en) * | 2008-06-24 | 2010-04-01 | Qlt Plug Delivery Inc | Combination treatment of glaucoma |
EP3298995A1 (en) | 2008-06-25 | 2018-03-28 | Novartis AG | Ocular implant with shape change capabilities |
EP2328527A1 (en) * | 2008-07-08 | 2011-06-08 | QLT Plug Delivery, Inc. | Lacrimal implant body including comforting agent |
CN102176931B (zh) | 2008-08-09 | 2015-03-04 | 麻省理工学院 | 治疗男性泌尿生殖组织和外周组织的可植入药物递送设备和方法 |
US20100204335A1 (en) * | 2008-12-01 | 2010-08-12 | Allergan, Inc. | Kit and composition for eyelash growth |
CA2747556A1 (en) * | 2008-12-19 | 2010-06-24 | Qlt Inc. | Substance delivering punctum implants and methods |
KR20110129869A (ko) * | 2009-01-23 | 2011-12-02 | 큐엘티 인코포레이티드 | 하나 이상의 제제의 서방형 전달 |
EP3735947B1 (en) | 2009-01-28 | 2022-05-04 | Alcon Inc. | Ocular implant delivery system |
US8623395B2 (en) | 2010-01-29 | 2014-01-07 | Forsight Vision4, Inc. | Implantable therapeutic device |
PL2391419T3 (pl) | 2009-01-29 | 2019-12-31 | Forsight Vision4, Inc. | Dostarczanie leku do tylnego odcinka |
US20100204325A1 (en) * | 2009-02-11 | 2010-08-12 | Allergan, Inc. | Valproic acid drug delivery systems and intraocular therapeutic uses thereof |
CN102395401B (zh) * | 2009-02-12 | 2015-08-19 | 因赛普特有限责任公司 | 经由水凝胶塞的药物递送 |
WO2010096822A2 (en) * | 2009-02-23 | 2010-08-26 | Qlt Plug Delivery, Inc. | Lacrimal implants and related methods |
EP2408409B8 (en) * | 2009-03-16 | 2016-06-08 | Endoshape, Inc. | Reliably retained shape memory ophthal-mological implants |
TWI495459B (zh) * | 2009-03-31 | 2015-08-11 | Johnson & Johnson Vision Care | 淚管塞(二) |
US9421127B2 (en) | 2009-03-31 | 2016-08-23 | Johnson & Johnson Vision Care, Inc. | Punctal plugs |
WO2010129545A2 (en) * | 2009-05-04 | 2010-11-11 | Psivida Us, Inc. | Porous silicon drug-eluting particles |
US10206813B2 (en) | 2009-05-18 | 2019-02-19 | Dose Medical Corporation | Implants with controlled drug delivery features and methods of using same |
EP4108216A1 (en) * | 2009-06-03 | 2022-12-28 | Forsight Vision5, Inc. | Anterior segment drug delivery |
CN102481438B (zh) | 2009-06-26 | 2013-09-18 | 塔里斯生物医药公司 | 可植入药物递送装置及制造所述装置的方法 |
WO2011022484A1 (en) | 2009-08-18 | 2011-02-24 | Replenish Pumps. Llc | Electrolytic drug-delivery pump with adaptive control |
US8808257B2 (en) | 2009-08-31 | 2014-08-19 | Johnson & Johnson Vision Care, Inc. | Methods and apparatus for pulsatile release of medicaments from a punctal plug |
US9017312B2 (en) | 2009-09-10 | 2015-04-28 | Taris Biomedical Llc | Implantable device for controlled drug delivery |
US20120245539A1 (en) | 2009-11-27 | 2012-09-27 | Qlt Inc. | Lacrimal implants including split and insertable drug core |
US8529492B2 (en) | 2009-12-23 | 2013-09-10 | Trascend Medical, Inc. | Drug delivery devices and methods |
WO2013022801A1 (en) * | 2011-08-05 | 2013-02-14 | Forsight Vision4, Inc. | Small molecule delivery with implantable therapeutic device |
US9259351B2 (en) | 2010-03-29 | 2016-02-16 | Johnson & Johnson Vision Care, Inc. | Punctal plugs |
US9259352B2 (en) | 2010-03-29 | 2016-02-16 | Johnson & Johnson Vision Care, Inc. | Punctal plugs |
US20110251568A1 (en) * | 2010-04-08 | 2011-10-13 | Beeley Nathan R F | Punctal plugs for controlled release of therapeutic agents |
US10617557B2 (en) | 2010-08-05 | 2020-04-14 | Forsight Vision4, Inc. | Combined drug delivery methods and apparatus |
US9283361B2 (en) | 2010-08-05 | 2016-03-15 | Taris Biomedical Llc | Implantable drug delivery devices for genitourinary sites |
AU2011285545B2 (en) | 2010-08-05 | 2014-03-13 | Forsight Vision4, Inc. | Injector apparatus and method for drug delivery |
CA2807554C (en) * | 2010-08-05 | 2021-10-26 | Forsight Vision4 Inc. | Implantable therapeutic device |
US8821457B2 (en) * | 2010-09-08 | 2014-09-02 | Johnson & Johnson Vision Care, Inc. | Punctal plug containing drug formulation |
US8591484B2 (en) | 2010-09-15 | 2013-11-26 | AlphaMed, Inc. | Lacrimal punctum measurement and occlusion |
US9022967B2 (en) | 2010-10-08 | 2015-05-05 | Sinopsys Surgical, Inc. | Implant device, tool, and methods relating to treatment of paranasal sinuses |
TWI615150B (zh) | 2010-11-01 | 2018-02-21 | 匹史維迪亞美利堅公司 | 用於傳遞治療劑之生物可分解之以矽為主的裝置 |
EP2640360A2 (en) | 2010-11-19 | 2013-09-25 | Forsight Vision4, Inc. | Therapeutic agent formulations for implanted devices |
US20140023692A1 (en) * | 2010-11-26 | 2014-01-23 | Lisa Claire Du Toit | Drug delivery device |
US20120157938A1 (en) * | 2010-12-16 | 2012-06-21 | Tokarski Jason M | Punctal plug with drug core retention features |
CA2823783C (en) | 2011-01-10 | 2023-03-21 | Taris Biomedical, Inc. | Lidocaine regimen for the use of sustained treatment of bladder pain and irritative voiding |
WO2012106714A1 (en) | 2011-02-04 | 2012-08-09 | Taris Biomedical, Inc. | Implantable device for controlled release of low solubility drug |
RU2456005C1 (ru) * | 2011-04-20 | 2012-07-20 | Общество с ограниченной ответственностью фирма "Биокор" | Способ приготовления биологически активного препарата |
US20120276186A1 (en) | 2011-04-29 | 2012-11-01 | Ghebremeskel Alazar N | Sustained release latanoprost implant |
US10245178B1 (en) | 2011-06-07 | 2019-04-02 | Glaukos Corporation | Anterior chamber drug-eluting ocular implant |
EP2726016B1 (en) | 2011-06-28 | 2023-07-19 | ForSight Vision4, Inc. | An apparatus for collecting a sample of fluid from a reservoir chamber of a therapeutic device for the eye |
US9974685B2 (en) | 2011-08-29 | 2018-05-22 | Mati Therapeutics | Drug delivery system and methods of treating open angle glaucoma and ocular hypertension |
DK3290024T3 (da) | 2011-08-29 | 2019-06-03 | Mati Therapeutics Inc | Vedvarende indgivelse af aktive midler til behandling af glaukom og okulær hypertension |
KR102192603B1 (ko) | 2011-09-14 | 2020-12-17 | 포사이트 비젼5, 인크. | 안내 삽입물 장치 및 방법 |
RS61758B1 (sr) | 2011-09-16 | 2021-05-31 | Forsight Vision4 Inc | Aparati za razmenu tečnosti |
US10226417B2 (en) | 2011-09-16 | 2019-03-12 | Peter Jarrett | Drug delivery systems and applications |
GB201120771D0 (en) * | 2011-12-02 | 2012-01-11 | Ljt Projects Ltd | tear duct resistance measuring system |
US8765210B2 (en) | 2011-12-08 | 2014-07-01 | Aquesys, Inc. | Systems and methods for making gelatin shunts |
TWI590843B (zh) | 2011-12-28 | 2017-07-11 | 信迪思有限公司 | 膜及其製造方法 |
WO2013116061A1 (en) | 2012-02-03 | 2013-08-08 | Forsight Vision4, Inc. | Insertion and removal methods and apparatus for therapeutic devices |
US10342700B2 (en) * | 2012-02-22 | 2019-07-09 | Ira H. Schachar | Device and method for treatment of retinal detachment and other maladies of the eye |
JP6403939B2 (ja) * | 2012-02-29 | 2018-10-10 | ジョンソン・アンド・ジョンソン・ビジョン・ケア・インコーポレイテッドJohnson & Johnson Vision Care, Inc. | 電圧が印加される収容アレイを有する涙点プラグ |
US9572964B2 (en) | 2012-04-11 | 2017-02-21 | Sinapsys Surgical, Inc. | Implantation tools, tool assemblies, kits and methods |
US10085633B2 (en) | 2012-04-19 | 2018-10-02 | Novartis Ag | Direct visualization system for glaucoma treatment |
US9241832B2 (en) | 2012-04-24 | 2016-01-26 | Transcend Medical, Inc. | Delivery system for ocular implant |
EP2844224B1 (en) | 2012-05-03 | 2018-04-11 | Mati Therapeutics Inc. | Drug delivery system for treating open angle glaucoma and ocular hypertension |
KR101969594B1 (ko) * | 2012-05-11 | 2019-04-16 | 서강대학교산학협력단 | 안내 약물 전달 임플란트 |
ES2633185T3 (es) | 2012-09-17 | 2017-09-19 | Novartis Ag | Dispositivos de implante ocular expansibles |
US9750636B2 (en) | 2012-10-26 | 2017-09-05 | Forsight Vision5, Inc. | Ophthalmic system for sustained release of drug to eye |
US9763829B2 (en) | 2012-11-14 | 2017-09-19 | Novartis Ag | Flow promoting ocular implant |
MX365304B (es) | 2013-01-25 | 2019-05-29 | Sinopsys Surgical Inc | Dispositivos de implante de acceso a seno paranasal y herramientas, métodos y kits relacionados. |
US10159600B2 (en) | 2013-02-19 | 2018-12-25 | Aquesys, Inc. | Adjustable intraocular flow regulation |
US9125723B2 (en) | 2013-02-19 | 2015-09-08 | Aquesys, Inc. | Adjustable glaucoma implant |
EP2968113B8 (en) | 2013-03-14 | 2020-10-28 | Forsight Vision4, Inc. | Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant |
BR112015022433B1 (pt) | 2013-03-15 | 2022-06-21 | Taris Biomedical Llc | Dispositivo de liberação de droga intravesical |
JP2016512839A (ja) | 2013-03-15 | 2016-05-09 | シヴィダ・ユーエス・インコーポレイテッドPsivida Us, Inc. | 治療物質の送達のための生体内分解性ケイ素系組成物 |
US9526654B2 (en) | 2013-03-28 | 2016-12-27 | Forsight Vision4, Inc. | Ophthalmic implant for delivering therapeutic substances |
US9987163B2 (en) | 2013-04-16 | 2018-06-05 | Novartis Ag | Device for dispensing intraocular substances |
CA2916249C (en) | 2013-06-21 | 2021-07-13 | DePuy Synthes Products, Inc. | Films and methods of manufacture |
CN113413393A (zh) | 2013-08-19 | 2021-09-21 | 塔里斯生物医药公司 | 多单元药物递送装置和方法 |
US9700459B2 (en) | 2013-10-16 | 2017-07-11 | Sinopsys Surgical, Inc. | Apparatuses, tools and kits relating to fluid manipulation treatments of paranasal sinuses |
CA2930027C (en) | 2013-11-14 | 2019-10-29 | Aquesys, Inc. | Intraocular shunt inserter |
HU231309B1 (hu) | 2014-02-25 | 2022-11-28 | Darholding Kft. | Nanostrukturált Indomethacint, gyógyszerészetileg elfogadott sóit és kokristályait tartalmazó készítmény és eljárás előállításukra |
JP6655610B2 (ja) | 2014-05-29 | 2020-02-26 | グローコス コーポレーション | 制御された薬物送達機能を備えるインプラント及びそれを使用する方法 |
US10258503B2 (en) | 2014-07-15 | 2019-04-16 | Forsight Vision4, Inc. | Ocular implant delivery device and method |
WO2016014996A1 (en) * | 2014-07-24 | 2016-01-28 | Sinopsys Surgical, Inc. | Apparatuses, tools, kits and methods relating to paranasal sinus access |
US9474756B2 (en) | 2014-08-08 | 2016-10-25 | Forsight Vision4, Inc. | Stable and soluble formulations of receptor tyrosine kinase inhibitors, and methods of preparation thereof |
RU2562515C1 (ru) * | 2014-08-19 | 2015-09-10 | федеральное государственное бюджетное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова" Министерства здравоохранения Российской Федерации | Интубационный набор для биканаликулярного дренирования слезоотводящих путей |
WO2016028774A1 (en) | 2014-08-19 | 2016-02-25 | The Regents Of The University Of California | Implants for localized drug delivery and methods of use thereof |
US10507101B2 (en) | 2014-10-13 | 2019-12-17 | W. L. Gore & Associates, Inc. | Valved conduit |
SG11201703726XA (en) * | 2014-11-10 | 2017-06-29 | Forsight Vision4 Inc | Expandable drug delivery devices and method of use |
CN107645951B (zh) * | 2014-11-25 | 2021-05-04 | 艾克思摩尔有限公司 | 用于递送一种或多种生物活性剂的组合物和方法 |
US11051982B2 (en) | 2014-12-17 | 2021-07-06 | Paul Gavaris | Canalicular plug, method and kit for treating dry eye |
RU2581823C1 (ru) * | 2015-03-17 | 2016-04-20 | федеральное государственное бюджетное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова" Министерства здравоохранения Российской Федерации | Дренаж для хирургического лечения глаукомы |
JP6766065B2 (ja) | 2015-03-31 | 2020-10-07 | カリフォルニア インスティチュート オブ テクノロジー | 長期埋め込み型センサおよび電子機器のための生体適合型パッケージング |
EP3283004A4 (en) | 2015-04-13 | 2018-12-05 | Forsight Vision5, Inc. | Ocular insert composition of semi-crystalline or crystalline pharmaceutically active agent |
EP3285850A1 (en) | 2015-04-23 | 2018-02-28 | TARIS Biomedical LLC | Drug delivery devices with drug-permeable component and methods |
WO2016187355A1 (en) * | 2015-05-20 | 2016-11-24 | Glaukos Corporation | Therapeutic drug compositions and implants for delivery of same |
WO2016205107A1 (en) * | 2015-06-16 | 2016-12-22 | The Regents Of The University Of Colorado, A Body Corporate | Nasolacrimal implants and related methods for tear stimulation |
WO2017007819A1 (en) * | 2015-07-06 | 2017-01-12 | The Regents Of The University Of Colorado, A Body Corporate | Lacrimal drainage system diagnostic implant |
CA2993182A1 (en) | 2015-07-22 | 2017-01-26 | Incept, Llc | Coated punctal plug |
US11925578B2 (en) | 2015-09-02 | 2024-03-12 | Glaukos Corporation | Drug delivery implants with bi-directional delivery capacity |
US11564833B2 (en) | 2015-09-25 | 2023-01-31 | Glaukos Corporation | Punctal implants with controlled drug delivery features and methods of using same |
US11458041B2 (en) | 2015-10-08 | 2022-10-04 | Ocular Therapeutix, Inc. | Punctal plug and bioadhesives |
CA3005238A1 (en) | 2015-11-20 | 2017-05-26 | Forsight Vision4, Inc. | Porous structures for extended release drug delivery devices |
RU2613435C1 (ru) * | 2015-12-17 | 2017-03-16 | Федеральное государственное автономное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова" Министерства здравоохранения Российской Федерации | Дренаж для хирургического лечения глаукомы |
RU2620249C1 (ru) * | 2015-12-17 | 2017-05-23 | Федеральное государственное автономное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова" Министерства здравоохранения Российской Федерации | Многослойный биодеградируемый глазной имплантат с дозированным высвобождением лекарственного вещества и способ его изготовления |
PE20181214A1 (es) * | 2015-12-21 | 2018-07-24 | Bayer Oy | Metodo para fabricar un dispositivo para la administracion de farmacos y un dispositivo para la administracion de farmacos fabricado segun el metodo |
CN109195556B (zh) | 2016-04-05 | 2021-03-26 | 弗赛特影像4股份有限公司 | 可植入眼睛药物递送装置 |
CA3022830A1 (en) | 2016-04-20 | 2017-10-26 | Harold Alexander Heitzmann | Bioresorbable ocular drug delivery device |
JP7054211B2 (ja) * | 2016-05-20 | 2022-04-13 | ザ リージェンツ オブ ザ ユニバーシティ オブ コロラド,ア ボディー コーポレイト | 涙腺ドラッグ送給デバイス |
GB2555373A (en) * | 2016-08-23 | 2018-05-02 | Reproductive Medicine And Gynaecology Associates Ltd | Implant |
EP4046609A1 (en) | 2016-09-30 | 2022-08-24 | Mati Therapeutics Inc. | Ophthalmic drug sustained release formulation and uses thereof |
US9925028B1 (en) * | 2016-11-15 | 2018-03-27 | Proximate Concepts Llc | Device for the delivery of a prosthetic implant and method of use thereof |
US10722335B1 (en) * | 2016-11-15 | 2020-07-28 | Proximate Concepts Llc | Device for the delivery of a prosthetic implant and method of use thereof |
US11406533B2 (en) | 2017-03-17 | 2022-08-09 | W. L. Gore & Associates, Inc. | Integrated aqueous shunt for glaucoma treatment |
EP3621512B1 (en) * | 2017-05-12 | 2024-02-28 | California Institute of Technology | Implantable extracompartmental pressure sensor |
CN111278401B (zh) * | 2017-05-30 | 2023-08-15 | 艾克思摩尔有限公司 | 递送抗生素大环内酯治疗干眼综合征的组合物和方法 |
TWI797136B (zh) | 2017-06-16 | 2023-04-01 | 美商亞斯庫拉科技公司 | 熱感應聚合物及其用途 |
US11332773B2 (en) | 2017-07-31 | 2022-05-17 | Keio University | Rapid tumorigenicity screening system |
CA3076375C (en) | 2017-09-20 | 2022-08-09 | Sinopsys Surgical, Inc. | Paranasal sinus fluid access implantation tools, assemblies, kits and methods |
WO2019071243A1 (en) | 2017-10-06 | 2019-04-11 | Foundry Therapeutics, Inc. | IMPLANTABLE DEPOSITS FOR CONTROLLED RELEASE OF THERAPEUTIC AGENTS |
KR20200093581A (ko) | 2017-11-21 | 2020-08-05 | 포사이트 비젼4, 인크. | 확장 가능한 포트 전달 시스템을 위한 유체 교환 기기 및 사용 방법 |
MX2020009754A (es) * | 2018-03-22 | 2020-10-08 | Alphamed Inc | Insertador de tapon en punto soluble intracanalicular. |
WO2020050968A1 (en) * | 2018-09-04 | 2020-03-12 | University Hospitals Health System, Inc. | Ocular device for treating glaucoma and related minimally invasive glaucoma surgery method |
US11678983B2 (en) | 2018-12-12 | 2023-06-20 | W. L. Gore & Associates, Inc. | Implantable component with socket |
US11850135B2 (en) | 2019-08-01 | 2023-12-26 | Paul H. Rosenberg Family Trust | Prosthetic implant delivery device utilizing surface active agents |
US11207267B2 (en) | 2019-10-02 | 2021-12-28 | Segal Innovations LLC | Bio-adhesive dissolving compounds and device |
US11701504B2 (en) | 2020-01-17 | 2023-07-18 | California Institute Of Technology | Implantable intracranial pressure sensor |
CN115066232A (zh) | 2020-02-06 | 2022-09-16 | 视觉治疗股份有限公司 | 用于治疗眼病的组合物和方法 |
US11338119B2 (en) | 2020-03-20 | 2022-05-24 | The Regents Of The University Of California | Implantable drug delivery devices for localized drug delivery |
US11173291B2 (en) | 2020-03-20 | 2021-11-16 | The Regents Of The University Of California | Implantable drug delivery devices for localized drug delivery |
US11344526B2 (en) | 2020-03-20 | 2022-05-31 | The Regents Of The University Of California | Implantable drug delivery devices for localized drug delivery |
HRP20230800T1 (hr) | 2020-03-25 | 2023-10-27 | Ocular Therapeutix, Inc. | Očni usadak koji sadrži inhibitor tirozin kinaze |
US20210338481A1 (en) * | 2020-04-20 | 2021-11-04 | Bruce B. Becker | Lacrimal gland implant for drug delivery and method |
EP3973952B1 (en) | 2020-09-24 | 2024-02-14 | Ocular Therapeutix, Inc. | Sustained release biodegradable intracanalicular inserts comprising a hydrogel and cyclosporine |
Family Cites Families (244)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3880991A (en) * | 1969-03-24 | 1975-04-29 | Brook David E | Polymeric article for dispensing drugs |
US3865108A (en) | 1971-05-17 | 1975-02-11 | Ortho Pharma Corp | Expandable drug delivery device |
US3828777A (en) | 1971-11-08 | 1974-08-13 | Alza Corp | Microporous ocular device |
US3949750A (en) | 1974-10-07 | 1976-04-13 | Freeman Jerre M | Punctum plug and method for treating keratoconjunctivitis sicca (dry eye) and other ophthalmic aliments using same |
US4014335A (en) | 1975-04-21 | 1977-03-29 | Alza Corporation | Ocular drug delivery device |
US4281654A (en) | 1980-04-07 | 1981-08-04 | Alza Corporation | Drug delivery system for controlled ocular therapy |
US4304765A (en) | 1980-10-14 | 1981-12-08 | Alza Corporation | Ocular insert housing steroid in two different therapeutic forms |
NZ200429A (en) * | 1981-04-30 | 1984-10-19 | Smith & Nephew Ass | Applicator for placing pharmaceutically active agent in contact with moist surface,e.g.,eye |
US5053030A (en) | 1984-11-07 | 1991-10-01 | Herrick Robert S | Intracanalicular implant for horizontal canalicular blockade treatment of the eye |
US5049142A (en) | 1984-11-07 | 1991-09-17 | Herrick Robert S | Intracanalicular implant for horizontal canalicular blockade treatment of the eye |
US4660546A (en) | 1984-11-07 | 1987-04-28 | Robert S. Herrick | Method for treating for deficiency of tears |
US5229128A (en) | 1986-06-11 | 1993-07-20 | Haddad Heskel M | Drug delivery ophthalmic insert and method of preparing same |
US5322691A (en) | 1986-10-02 | 1994-06-21 | Sohrab Darougar | Ocular insert with anchoring protrusions |
US4747404A (en) | 1986-11-10 | 1988-05-31 | Kresge Eye Institute Of Wayne State University | Foldable intraocular lens inserter |
US4886488A (en) | 1987-08-06 | 1989-12-12 | White Thomas C | Glaucoma drainage the lacrimal system and method |
GB8806367D0 (en) * | 1988-03-17 | 1988-04-13 | Erba Carlo Spa | Siloxane matrices with internal non-uniform drug distribution |
US4915684A (en) | 1988-06-21 | 1990-04-10 | Mackeen Donald L | Method and apparatus for modulating the flow of lacrimal fluid through a punctum and associated canaliculus |
US4915664A (en) | 1988-12-22 | 1990-04-10 | Erik Bakker | Toy glider with wing converging mechanism |
US5133159A (en) | 1989-01-13 | 1992-07-28 | Nestle S.A. | Method for polishing silicone products |
US4959048A (en) | 1989-01-17 | 1990-09-25 | Helix Medical, Inc. | Lacrimal duct occluder |
US5098443A (en) * | 1989-03-23 | 1992-03-24 | University Of Miami | Method of implanting intraocular and intraorbital implantable devices for the controlled release of pharmacological agents |
US5128058A (en) | 1989-05-31 | 1992-07-07 | Hoya Corporation | Contact lens cleaner containing a microcapsular polishing agent |
IE910450A1 (en) | 1990-02-15 | 1991-08-28 | Bausch & Lomb | Soft contact lens processing aid |
US5163959A (en) | 1990-03-29 | 1992-11-17 | Herrick Robert S | Method for treating an eye with a canalicular implant having a collapsible flared section |
US5171270A (en) | 1990-03-29 | 1992-12-15 | Herrick Robert S | Canalicular implant having a collapsible flared section and method |
US5041081A (en) | 1990-05-18 | 1991-08-20 | Odrich Ronald B | Ocular implant for controlling glaucoma |
US5116371A (en) | 1990-07-06 | 1992-05-26 | Christensen James M | Prosthesis with improved biocompatibility |
US5143724A (en) * | 1990-07-09 | 1992-09-01 | Biomatrix, Inc. | Biocompatible viscoelastic gel slurries, their preparation and use |
US5077033A (en) * | 1990-08-07 | 1991-12-31 | Mediventures Inc. | Ophthalmic drug delivery with thermo-irreversible gels of polxoxyalkylene polymer and ionic polysaccharide |
KR100281609B1 (ko) | 1991-12-27 | 2001-02-15 | 폴락 돈나 엘. | 유효 제제를 포함하는 분산액의 동일 반응계내 생성 및 방출을 조절하는 약물 전달 장치 |
US5283063A (en) | 1992-01-31 | 1994-02-01 | Eagle Vision | Punctum plug method and apparatus |
US5334137A (en) | 1992-02-21 | 1994-08-02 | Eagle Vision, Inc. | Lacrimal fluid control device |
US5254089A (en) * | 1992-04-02 | 1993-10-19 | Boston Scientific Corp. | Medication dispensing balloon catheter |
US5178635A (en) | 1992-05-04 | 1993-01-12 | Allergan, Inc. | Method for determining amount of medication in an implantable device |
US5514379A (en) * | 1992-08-07 | 1996-05-07 | The General Hospital Corporation | Hydrogel compositions and methods of use |
US5469867A (en) | 1992-09-02 | 1995-11-28 | Landec Corporation | Cast-in place thermoplastic channel occluder |
US5318513A (en) | 1992-09-24 | 1994-06-07 | Leib Martin L | Canalicular balloon fixation stent |
FR2700265B1 (fr) * | 1993-01-08 | 1995-03-31 | France Chirurgie Instr | Bouchon méatique pour pathologie lacrymale. |
US5707643A (en) | 1993-02-26 | 1998-01-13 | Santen Pharmaceutical Co., Ltd. | Biodegradable scleral plug |
US6117907A (en) * | 1993-04-14 | 2000-09-12 | Sher; Neal A. | Topical treatment of ocular pain after corneal surgery |
US5824048A (en) | 1993-04-26 | 1998-10-20 | Medtronic, Inc. | Method for delivering a therapeutic substance to a body lumen |
US5417651A (en) | 1993-07-01 | 1995-05-23 | Guena; Nicolas | Punctum plug and monocanalicular probe for lacrimal pathology |
US5770589A (en) | 1993-07-27 | 1998-06-23 | The University Of Sydney | Treatment of macular degeneration |
US5423777A (en) | 1993-10-27 | 1995-06-13 | Tajiri; Akira | Punctum plug |
US5443505A (en) * | 1993-11-15 | 1995-08-22 | Oculex Pharmaceuticals, Inc. | Biocompatible ocular implants |
US6350781B1 (en) * | 1994-01-14 | 2002-02-26 | Lee Shahinia, Jr. | Method and analgesic preparations for sustained and extended corneal analgesia with subanesthetic concentrations of lidocaine |
US5466233A (en) | 1994-04-25 | 1995-11-14 | Escalon Ophthalmics, Inc. | Tack for intraocular drug delivery and method for inserting and removing same |
JP3486758B2 (ja) | 1994-06-24 | 2004-01-13 | 株式会社高研 | 注入可能な涙小管閉鎖剤 |
JPH0878130A (ja) | 1994-09-08 | 1996-03-22 | Wako:Kk | 接地極の埋設方法 |
US6416760B2 (en) | 1995-01-26 | 2002-07-09 | Societe L'oreal | Therapeutic/cosmetic compositions comprising CGRP antagonists for treating sensitive human skin |
DE69633074T2 (de) * | 1995-05-14 | 2004-12-30 | Optonol Ltd. | Intraokulares implantat, einführgerät sowie implantierungsverfahren |
AU6107696A (en) * | 1995-06-07 | 1996-12-30 | Keravision, Inc. | Radial intrastromal corneal insert and a method of insertion |
US6149684A (en) | 1995-06-07 | 2000-11-21 | Herrick; Robert S. | Punctum plug having a thin elongated lip and a distal starting tip and method of using |
US5723005A (en) | 1995-06-07 | 1998-03-03 | Herrick Family Limited Partnership | Punctum plug having a collapsible flared section and method |
US5766243A (en) | 1995-08-21 | 1998-06-16 | Oasis Medical, Inc. | Abrasive polished canalicular implant |
US5773019A (en) | 1995-09-27 | 1998-06-30 | The University Of Kentucky Research Foundation | Implantable controlled release device to deliver drugs directly to an internal portion of the body |
US5741292A (en) | 1995-10-26 | 1998-04-21 | Eagle Vision | Punctum dilating and plug inserting instrument with push-button plug release |
US6441047B2 (en) | 1995-11-17 | 2002-08-27 | Alcon Manufacturing Ltd.. | Combination therapy for treating glaucoma |
WO1997020578A1 (en) * | 1995-12-04 | 1997-06-12 | University Of Miami | Non-preserved topical corticosteroid for treatment of dry eye, filamentary keratitis, and delayed tear clearance |
US5824073A (en) | 1996-03-18 | 1998-10-20 | Peyman; Gholam A. | Macular indentor for use in the treatment of subretinal neovascular membranes |
FR2747033B1 (fr) * | 1996-04-03 | 1998-05-22 | Parrat Michel Jesus Hubert | Obturateur meatique dynamique pour canalicules lacrymaux |
JP3675035B2 (ja) | 1996-06-10 | 2005-07-27 | トヨタ自動車株式会社 | 内燃機関の燃料噴射量制御装置 |
JPH1033584A (ja) | 1996-07-26 | 1998-02-10 | M L C:Kk | 涙道挿管器具 |
US5928662A (en) * | 1996-07-31 | 1999-07-27 | Phillips; Andrew F. | Ocular drug delivery device |
JP3345428B2 (ja) | 1996-08-20 | 2002-11-18 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 合成甲状腺ホルマン組成物を使用した眼の処置 |
US5993407A (en) | 1996-10-25 | 1999-11-30 | Moazed; Kambiz Thomas | Transnasal lacrimal insert |
DE69712905T2 (de) | 1996-11-01 | 2002-11-21 | Alcon Lab Inc | Polierverfahren für weiche acrylgegenstände |
WO1998033461A1 (fr) | 1997-02-04 | 1998-08-06 | Alain Fouere | Tampon meatique vissable pour canal lacrymal |
US6016806A (en) | 1997-03-27 | 2000-01-25 | Eaglevision, Inc | Punctum plug |
US6041785A (en) | 1997-03-27 | 2000-03-28 | Eaglevision, Inc. | Punctum plug |
US6082362A (en) | 1997-03-27 | 2000-07-04 | Eagle Vision, Inc. | Punctum plug |
US6027470A (en) | 1998-06-10 | 2000-02-22 | Eagle Vision, Inc. | Punctum plug and method for inserting the same into the punctual opening |
PT981327E (pt) * | 1997-05-07 | 2003-02-28 | Galen Chemicals Ltd | Dispositivos intravaginais de libertacao de farmacos para a administracao de testosterona e percursores da testosterona |
US5961370A (en) | 1997-05-08 | 1999-10-05 | Chiron Vision Corporation | Intraocular lens tumbling process using coated beads |
MY125870A (en) | 1997-07-25 | 2006-08-30 | Alza Corp | Osmotic delivery system flow modulator apparatus and method |
US6306426B1 (en) | 1997-08-11 | 2001-10-23 | Allergan Sales, Inc. | Implant device with a retinoid for improved biocompatibility |
US5830171A (en) | 1997-08-12 | 1998-11-03 | Odyssey Medical, Inc. | Punctal occluder |
US5902598A (en) * | 1997-08-28 | 1999-05-11 | Control Delivery Systems, Inc. | Sustained release drug delivery devices |
US6060439A (en) | 1997-09-29 | 2000-05-09 | Kyzen Corporation | Cleaning compositions and methods for cleaning resin and polymeric materials used in manufacture |
US6335335B2 (en) | 1997-11-05 | 2002-01-01 | Senju Pharmaceutical Co., Ltd. | Prolonged-action eye drop |
US5947974A (en) | 1997-12-09 | 1999-09-07 | Allergan | Folding device and method for an intraocular lens |
US6646001B2 (en) | 1997-12-19 | 2003-11-11 | Alcon Manufacturing, Ltd. | Use of non-steroidal anti-inflammatory agents in combination with prostaglandin FP receptor agonists to treat glaucoma and ocular hypertension |
NL1008090C2 (nl) | 1998-01-22 | 1999-07-26 | Lubberman Bernardus H M | Plug voor het afsluiten van een traanbuis. |
US6290684B1 (en) | 1998-03-02 | 2001-09-18 | Herrick Family Limited Partnership | Punctum plug having a collapsible expanded section and distal tip extending substantially perpendicular thereto and method of inserting same |
WO1999044553A1 (en) | 1998-03-02 | 1999-09-10 | Herrick Family Limited Partnership | A punctum plug having a collapsible flared section and method |
US6512747B1 (en) | 1998-03-05 | 2003-01-28 | Nippon Telegraph And Telephone Corporation | ATM transmission system |
US6196993B1 (en) * | 1998-04-20 | 2001-03-06 | Eyelab Group, Llc | Ophthalmic insert and method for sustained release of medication to the eye |
US6015433A (en) * | 1998-05-29 | 2000-01-18 | Micro Therapeutics, Inc. | Rolled stent with waveform perforation pattern |
US6224630B1 (en) * | 1998-05-29 | 2001-05-01 | Advanced Bio Surfaces, Inc. | Implantable tissue repair device |
US6306114B1 (en) | 1998-06-16 | 2001-10-23 | Eagle Vision, Inc. | Valved canalicular plug for lacrimal duct occlusion |
US6117441A (en) * | 1998-07-02 | 2000-09-12 | The Population Council, Inc. | Silicone core long term androgen delivery implant |
DK1037627T3 (da) | 1998-07-14 | 2001-10-01 | Alcon Lab Inc | Anvendelse af 11-(3-dimethylamino-propyliden)-6, 11-dihydrodibenz[b,e]oxepin-2-eddikesyre og af farmaceutisk acceptable salte deraf til fremstillingen af et lægemiddel til behandlingen af non-allergiske... |
US6225348B1 (en) * | 1998-08-20 | 2001-05-01 | Alfred W. Paulsen | Method of treating macular degeneration with a prostaglandin derivative |
JP2000070296A (ja) | 1998-08-27 | 2000-03-07 | M L C:Kk | 涙道内挿管器具 |
US6095901A (en) | 1998-12-09 | 2000-08-01 | Alcon Laboratories, Inc. | Polishing method for soft acrylic articles |
US20040121014A1 (en) | 1999-03-22 | 2004-06-24 | Control Delivery Systems, Inc. | Method for treating and/or preventing retinal diseases with sustained release corticosteroids |
US6234175B1 (en) | 1999-03-23 | 2001-05-22 | Medennium, Inc. | Smart ocular plug design and method of insertion for punctal and intracanalicular implants |
US6383192B1 (en) | 1999-04-28 | 2002-05-07 | Mlc Limited Company | Apparatus for intubation of lacrimal duct |
US6428502B1 (en) | 1999-06-25 | 2002-08-06 | Alcon Manufacturing, Ltd. | Punctal cannula |
US6706275B1 (en) | 1999-09-08 | 2004-03-16 | Matthew W. Camp | Scleral plug system |
ES2315598T3 (es) * | 1999-10-21 | 2009-04-01 | Alcon, Inc. | Dispositivo para la administracion de farmacos. |
US6331313B1 (en) | 1999-10-22 | 2001-12-18 | Oculex Pharmaceticals, Inc. | Controlled-release biocompatible ocular drug delivery implant devices and methods |
US6264971B1 (en) | 1999-11-04 | 2001-07-24 | Btg International Limited | Ocular insert |
US6566345B2 (en) | 2000-04-28 | 2003-05-20 | Fziomed, Inc. | Polyacid/polyalkylene oxide foams and gels and methods for their delivery |
US20050119737A1 (en) * | 2000-01-12 | 2005-06-02 | Bene Eric A. | Ocular implant and methods for making and using same |
US6344047B1 (en) | 2000-02-02 | 2002-02-05 | Eagle Vision | Instrument for inserting a punctum plug and method for manufacturing the instrument |
US7867186B2 (en) | 2002-04-08 | 2011-01-11 | Glaukos Corporation | Devices and methods for treatment of ocular disorders |
US6638239B1 (en) | 2000-04-14 | 2003-10-28 | Glaukos Corporation | Apparatus and method for treating glaucoma |
US7708711B2 (en) | 2000-04-14 | 2010-05-04 | Glaukos Corporation | Ocular implant with therapeutic agents and methods thereof |
US6375972B1 (en) | 2000-04-26 | 2002-04-23 | Control Delivery Systems, Inc. | Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof |
US20040208910A1 (en) * | 2000-04-26 | 2004-10-21 | Control Delivery Systems, Inc. | Sustained release device and method for ocular delivery of adrenergic agents |
US20040175410A1 (en) | 2000-04-26 | 2004-09-09 | Control Delivery Systems, Inc. | Sustained release device and method for ocular delivery of carbonic anhydrase inhibitors |
US6371122B1 (en) | 2000-06-20 | 2002-04-16 | Robert M. Mandelkorn | Gauge/dilator apparatus |
US6629533B1 (en) | 2000-06-30 | 2003-10-07 | Eagle Vision, Inc. | Punctum plug with at least one anchoring arm |
AU2001234337A1 (en) * | 2000-08-04 | 2002-02-18 | Medennium, Inc. | Ocular plug for punctal and intracanalicular implants |
US6534693B2 (en) * | 2000-11-06 | 2003-03-18 | Afmedica, Inc. | Surgically implanted devices having reduced scar tissue formation |
US7041868B2 (en) * | 2000-12-29 | 2006-05-09 | Kimberly-Clark Worldwide, Inc. | Bioabsorbable wound dressing |
EP1345588A2 (en) | 2000-12-29 | 2003-09-24 | Bausch & Lomb Incorporated | Sustained release drug delivery devices |
US6964781B2 (en) | 2001-01-03 | 2005-11-15 | Bausch & Lomb Incorporated | Sustained release drug delivery devices with prefabricated permeable plugs |
CA2433528A1 (en) | 2001-01-26 | 2002-08-01 | Bausch & Lomb Incorporated | Improved process for the production of sustained release drug delivery devices |
US20020193441A1 (en) | 2001-02-21 | 2002-12-19 | Robertson Stella M. | Prostanoid therapies for the treatment of glaucoma |
US6713081B2 (en) | 2001-03-15 | 2004-03-30 | The United States Of America As Represented By The Department Of Health And Human Services | Ocular therapeutic agent delivery devices and methods for making and using such devices |
US6981958B1 (en) | 2001-05-02 | 2006-01-03 | Glaukos Corporation | Implant with pressure sensor for glaucoma treatment |
US7431710B2 (en) | 2002-04-08 | 2008-10-07 | Glaukos Corporation | Ocular implants with anchors and methods thereof |
ES2304438T3 (es) | 2001-04-07 | 2008-10-16 | Glaukos Corporation | Stent de glaucoma para el tratamiento del glaucoma. |
US6605108B2 (en) | 2001-04-13 | 2003-08-12 | Eagle Vision, Inc. | Monocanalicular stent |
US6982090B2 (en) | 2001-05-10 | 2006-01-03 | Gillespie Donald E | More easily visualized punctum plug configurations |
US7404825B2 (en) | 2001-06-11 | 2008-07-29 | Herrick Ii Robert S | Implant capable of forming a differential image in an eye |
US6743439B1 (en) * | 2001-06-27 | 2004-06-01 | Alcon, Inc. | Ophthalmic compositions containing copolymers of sulfonated styrene and maleic anhydride |
CA2446741C (en) * | 2001-07-23 | 2009-09-29 | Alcon, Inc. | Ophthalmic drug delivery device |
KR20040024873A (ko) * | 2001-08-03 | 2004-03-22 | 글루코마 리서치 테크널러지스 인코포레이션 | 녹내장과 노안 치료를 위한 공막내 이식장치와 그 방법 |
FR2829019B3 (fr) | 2001-08-31 | 2003-10-31 | Alain Fouere | Bouchons lacrymaux et methodes de mise en place de ces dispositifs |
BR0212052A (pt) | 2001-09-11 | 2004-08-17 | Smart Drug Systems Inc | Preparação de composição farmacêutica de liberação prolongada |
US6996063B2 (en) | 2001-11-16 | 2006-02-07 | Asustek Computer Inc. | Applicable PDU range test and calculation for window-based polling |
FR2833175B1 (fr) | 2001-12-06 | 2004-05-14 | Sobem | Dispositif de controle de debit, a usage medical |
US7001615B1 (en) | 2001-12-07 | 2006-02-21 | Alcon, Inc. | Sustained release ophthalmic, otic and nasal suspension |
US6729939B2 (en) | 2001-12-17 | 2004-05-04 | Bausch & Lomb Incorporated | Polishing method for intraocular lens |
FR2834446B1 (fr) | 2002-01-08 | 2004-02-13 | Ioltechnologie Production | Clou meatique a expansion |
EP1466969A4 (en) | 2002-01-18 | 2006-02-01 | Takara Bio Inc | SULFATED FUCAN |
WO2003061625A2 (en) * | 2002-01-18 | 2003-07-31 | Snyder Michael E | Sustained release ophthalmological device and method of making and using the same |
TW200305424A (en) * | 2002-01-29 | 2003-11-01 | Santen Pharmaceutical Co Ltd | Glaucoma-treating agent comprising bunazosin and prostaglandin |
US7204995B2 (en) | 2002-01-31 | 2007-04-17 | El-Sherif Dalia M | Treatment and control of dry eye by use of biodegradable polymer capsules |
US20040116524A1 (en) * | 2002-02-04 | 2004-06-17 | Cohen Ben Z. | Method of administering opthalmic fluids |
AU2003218127B2 (en) * | 2002-03-11 | 2007-07-12 | Alcon, Inc. | Implantable drug delivery system |
US20040147870A1 (en) | 2002-04-08 | 2004-07-29 | Burns Thomas W. | Glaucoma treatment kit |
US9301875B2 (en) | 2002-04-08 | 2016-04-05 | Glaukos Corporation | Ocular disorder treatment implants with multiple opening |
AU2003234439A1 (en) * | 2002-05-07 | 2003-11-11 | Control Delivery Systems, Inc. | Processes for forming a drug delivery device |
US8871241B2 (en) | 2002-05-07 | 2014-10-28 | Psivida Us, Inc. | Injectable sustained release delivery devices |
US20040043067A1 (en) | 2002-06-19 | 2004-03-04 | Salamone Joseph C. | Fluorosiloxane matrix controlled diffusion drug delivery systems |
US6866563B2 (en) | 2002-06-27 | 2005-03-15 | Bausch & Lomb Incorporated | Apparatus and method for target polishing intraocular lenses |
FR2841770B1 (fr) | 2002-07-05 | 2004-10-01 | Ioltechnologie Production | Clou meatique d'obturation d'un meat lacrymal |
FR2844182B1 (fr) | 2002-09-11 | 2004-12-03 | Humanoptics Ag | Bouchon d'obturation d'un canalicule lacrymal |
US7169163B2 (en) | 2002-09-30 | 2007-01-30 | Bruce Becker | Transnasal method and catheter for lacrimal system |
US7785578B2 (en) | 2002-10-11 | 2010-08-31 | Aciont, Inc. | Non-invasive ocular drug delivery |
DE60221669T2 (de) | 2002-10-16 | 2008-05-21 | Alcatel Lucent | Paketvermittlung für Paketdatenübertragungssysteme in einer Multikanalfunkanordnung |
US7354574B2 (en) * | 2002-11-07 | 2008-04-08 | Advanced Ocular Systems Limited | Treatment of ocular disease |
US7580394B2 (en) | 2002-11-27 | 2009-08-25 | Nokia Corporation | System and method for collision-free transmission scheduling in a network |
EP1972344A1 (en) * | 2002-12-20 | 2008-09-24 | Chakshu Research, Inc. | Ophthalmic formulation for the prevention and treatment of ocular conditions |
US20040144392A1 (en) * | 2003-01-23 | 2004-07-29 | Mueller Richard L. | Breast nipple duct protective device |
BRPI0406879B1 (pt) * | 2003-01-24 | 2015-12-22 | Control Delivery Sys Inc | dispositivo de liberação de droga de liberação sustentada |
BRPI0406880A (pt) * | 2003-01-24 | 2006-01-03 | Control Delivery Sys Inc | Dispositivo de liberação sustentada e método para a liberação ocular de inibidores de anidrase carbÈnicos |
US8149707B2 (en) | 2003-02-12 | 2012-04-03 | Rockstar Bidco, LP | Minimization of radio resource usage in multi-hop networks with multiple routings |
US20040170685A1 (en) | 2003-02-26 | 2004-09-02 | Medivas, Llc | Bioactive stents and methods for use thereof |
PT2177620E (pt) * | 2003-03-05 | 2015-02-16 | Halozyme Inc | Glicoproteína hialuronidase solúvel (shasegp), processo para preparação da mesma, suas utilizações e composições farmacêuticas que a compreendem |
US20050283109A1 (en) | 2003-03-07 | 2005-12-22 | Peyman Gholam A | Method and apparatus for lacrimal canal obstruction |
US7065376B2 (en) | 2003-03-20 | 2006-06-20 | Microsoft Corporation | Multi-radio unification protocol |
US20040193095A1 (en) * | 2003-03-29 | 2004-09-30 | Shadduck John H. | Implants for treating ocular hypertension, methods of use and methods of fabrication |
US20050255144A1 (en) * | 2003-04-09 | 2005-11-17 | Directcontact Llc | Methods and articles for the delivery of medicaments to the eye for the treatment of posterior segment diseases |
AU2004237774B2 (en) | 2003-05-02 | 2009-09-10 | Surmodics, Inc. | Implantable controlled release bioactive agent delivery device |
US7017580B2 (en) | 2003-05-22 | 2006-03-28 | Clarity Corporation | Punctum plug system including a punctum plug and passive insertion tool therefor |
US7204253B2 (en) | 2003-05-22 | 2007-04-17 | Clarity Corporation | Punctum plug |
US20040236343A1 (en) | 2003-05-23 | 2004-11-25 | Taylor Jon B. | Insertion tool for ocular implant and method for using same |
CA2467410A1 (en) * | 2003-05-27 | 2004-11-27 | Synphora Ab | Method for treatment of glaucoma and ocular hypertension with prostaglandin analgoues without melanogenic side-effect |
JP4104137B2 (ja) | 2003-05-30 | 2008-06-18 | 有限会社エム・エル・シー | 涙点プラグ |
US7662864B2 (en) | 2003-06-04 | 2010-02-16 | Rutgers, The State University Of New Jersey | Solution polymerization processes to prepare a polymer that degrades to release a physiologically active agent |
JP4339635B2 (ja) | 2003-06-12 | 2009-10-07 | 有限会社エム・エル・シー | 涙点プラグ |
US6994684B2 (en) | 2003-06-16 | 2006-02-07 | Alphamed Inc. | Punctum plugs having fluid collecting recesses and methods of punctal occlusion |
US20040265356A1 (en) | 2003-06-30 | 2004-12-30 | Bausch & Lomb Incorporated | Drug delivery device |
US20070043332A1 (en) | 2003-07-10 | 2007-02-22 | Galen (Chemiclas) Liimited | Intravaginal drug delivery devices |
JP4280128B2 (ja) | 2003-08-19 | 2009-06-17 | 有限会社エム・エル・シー | 涙点プラグ |
CN1882338A (zh) * | 2003-09-18 | 2006-12-20 | 马库赛特公司 | 经巩膜递送 |
JP2007507498A (ja) * | 2003-10-03 | 2007-03-29 | アラーガン、インコーポレイテッド | 充血の少ない緑内障処置のためのプロスタグランジン関連化合物およびトレフォイルファクターファミリーペプチドを含む組成物および方法 |
JP2005110765A (ja) | 2003-10-03 | 2005-04-28 | M L C:Kk | 涙点プラグセット |
JP2005110930A (ja) | 2003-10-07 | 2005-04-28 | M L C:Kk | 涙点プラグセット |
US20050129731A1 (en) * | 2003-11-03 | 2005-06-16 | Roland Horres | Biocompatible, biostable coating of medical surfaces |
US20050095269A1 (en) | 2003-11-04 | 2005-05-05 | Ainpour Parviz R. | Gel plug for blockage of the canaliculus |
NZ581461A (en) * | 2003-11-13 | 2011-04-29 | Psivida Inc | Injectable sustained release delivery devices |
US7291125B2 (en) | 2003-11-14 | 2007-11-06 | Transcend Medical, Inc. | Ocular pressure regulation |
ES2347648T3 (es) | 2003-12-17 | 2010-11-03 | Telefonaktiebolaget Lm Ericsson (Publ) | Un metodo, un sistema, un terminal y un producto de progrma de ordenador para seleccionar un sistema de acceso de radio en un sistema de acceso multiple. |
EP1700414B1 (en) | 2003-12-29 | 2009-05-06 | Electronics and Telecommunications Research Institute | Method for creating feedback messages for arq in a mobile communication system |
US20050220882A1 (en) | 2004-03-04 | 2005-10-06 | Wilson Pritchard | Materials for medical implants and occlusive devices |
US20050197614A1 (en) | 2004-03-04 | 2005-09-08 | Wilson Pritchard | Occlusive biomedical devices, punctum plugs, and methods of use thereof |
US20050232972A1 (en) | 2004-04-15 | 2005-10-20 | Steven Odrich | Drug delivery via punctal plug |
JP2004202276A (ja) | 2004-04-16 | 2004-07-22 | M L C:Kk | 涙道再建用挿管器具 |
US7799336B2 (en) * | 2004-04-30 | 2010-09-21 | Allergan, Inc. | Hypotensive lipid-containing biodegradable intraocular implants and related methods |
US20050244461A1 (en) * | 2004-04-30 | 2005-11-03 | Allergan, Inc. | Controlled release drug delivery systems and methods for treatment of an eye |
JP2005312835A (ja) | 2004-04-30 | 2005-11-10 | M L C:Kk | 糸で補強した涙道ステント |
US8425929B2 (en) * | 2004-04-30 | 2013-04-23 | Allergan, Inc. | Sustained release intraocular implants and methods for preventing retinal dysfunction |
US20050244469A1 (en) | 2004-04-30 | 2005-11-03 | Allergan, Inc. | Extended therapeutic effect ocular implant treatments |
JP4644438B2 (ja) | 2004-05-11 | 2011-03-02 | 有限会社エム・エル・シー | ツバつき涙道ステント |
JP4510511B2 (ja) | 2004-05-18 | 2010-07-28 | 有限会社エム・エル・シー | ツバを円盤で補強した涙道ステント及び涙道プラグ |
JP2008504938A (ja) | 2004-07-02 | 2008-02-21 | レイザー,エリオット | 治療媒体送出装置およびその送出装置を用いて治療媒体を眼に送り出す方法 |
EP1778198A1 (en) * | 2004-07-26 | 2007-05-02 | Clarity Corporation | Implantable device having reservoir with controlled release of medication and method of manufacturing the same |
US7117870B2 (en) * | 2004-07-26 | 2006-10-10 | Clarity Corporation | Lacrimal insert having reservoir with controlled release of medication and method of manufacturing the same |
US20060020253A1 (en) | 2004-07-26 | 2006-01-26 | Prescott Anthony D | Implantable device having reservoir with controlled release of medication and method of manufacturing the same |
WO2006031658A2 (en) | 2004-09-10 | 2006-03-23 | Allergan, Inc. | Therapeutic lacrimal canalicular inserts and related methods |
US20060074370A1 (en) | 2004-09-24 | 2006-04-06 | Medennium, Inc. | Ocular occluder and method of insertion |
RU2007115853A (ru) * | 2004-10-04 | 2008-11-10 | КьюЭлТи ЮЭсЭй, ИНК. (US) | Композиция, применимая в качестве имплантата с контролируемым высвобождением |
EP1827462A4 (en) | 2004-11-24 | 2012-01-04 | Therakine Ltd | IMPLANT FOR INTRAOCULAR DRUG DELIVERY |
CN1790976A (zh) | 2004-12-17 | 2006-06-21 | 松下电器产业株式会社 | 用于多天线传输中的重传方法 |
US7986633B2 (en) | 2004-12-27 | 2011-07-26 | Lg Electronics Inc. | Method of controlling data transmission for multimedia and broadcasting services in a broadband wireless access system |
CN100394900C (zh) * | 2005-02-02 | 2008-06-18 | 周星 | 螺旋弹簧型人工泪道 |
DE602005001441T2 (de) | 2005-03-04 | 2007-10-31 | Matsushita Electric Industrial Co., Ltd., Kadoma | Verfahren und Vorrichtung zur Synchronisation der physikalischen Protokollschichten in heterogenen Mobilkommunikationsnetzwerken |
US20060233858A1 (en) | 2005-03-08 | 2006-10-19 | Allergan, Inc. | Systems and methods providing targeted intraocular drug delivery |
WO2006122414A1 (en) * | 2005-05-17 | 2006-11-23 | Matregen Corp. | Depot for sustained and controlled delivery of methotrexate |
US20060292099A1 (en) * | 2005-05-25 | 2006-12-28 | Michael Milburn | Treatment of eye disorders with sirtuin modulators |
WO2007009061A2 (en) * | 2005-07-13 | 2007-01-18 | Anthrogenesis Corporation | Ocular plug formed from placenta derived collagen biofabric |
US7862532B2 (en) | 2005-10-07 | 2011-01-04 | Delta Life Sciences, Inc. | Punctum plugs having insertion guides and strengthening beams |
US20070088444A1 (en) * | 2005-10-13 | 2007-04-19 | Robert A Hodorek | Method for repairing a bone defect using a formable implant which hardens in vivo |
US20070132125A1 (en) | 2005-12-08 | 2007-06-14 | Bausch & Lomb Incorporated | Use of a super-cooled fluid in lens processing |
JP4078371B2 (ja) | 2006-01-27 | 2008-04-23 | 章弘 小栗 | 涙点プラグ |
DK2010096T3 (en) * | 2006-03-31 | 2017-10-02 | Mati Therapeutics Inc | NASOLACRIMAL DRAINAGE SYSTEM IMPLANTS FOR PHARMACEUTICAL THERAPY |
US9173773B2 (en) | 2006-06-21 | 2015-11-03 | Johnson & Johnson Vision Care, Inc. | Punctal plugs for the delivery of active agents |
US20080045911A1 (en) | 2006-06-21 | 2008-02-21 | Borgia Maureen J | Punctal plugs for the delivery of active agents |
US9474645B2 (en) | 2006-06-21 | 2016-10-25 | Johnson & Johnson Vision Care, Inc. | Punctal plugs for the delivery of active agents |
US20080152694A1 (en) * | 2006-07-20 | 2008-06-26 | Neurosystec Corporation | Devices, Systems and Methods for Ophthalmic Drug Delivery |
FR2908042B1 (fr) | 2006-11-08 | 2009-06-05 | Bruno Fayet | Ensemble d'intubation monocanaliculonasal et/ou monocanaliculaire,notamment pour l'imperforation lacrymonasale. |
JP2010514517A (ja) * | 2006-12-26 | 2010-05-06 | キューエルティー プラグ デリバリー,インク. | 視覚欠損の抑制のための薬物送達インプラント |
UY30883A1 (es) | 2007-01-31 | 2008-05-31 | Alcon Res | Tapones punctales y metodos de liberacion de agentes terapeuticos |
US20080299176A1 (en) | 2007-05-30 | 2008-12-04 | Yu-Chin Lai | Drug delivery device comprising crosslinked polyurethane-siloxane-containing copolymers |
CA2698508C (en) | 2007-09-07 | 2017-06-06 | Alan R. Rapacki | Lacrimal implants and related methods |
CN101969897A (zh) | 2007-09-07 | 2011-02-09 | Qlt栓塞输送公司 | 用于泪腺植入物的插入和抽出工具 |
WO2009035565A1 (en) | 2007-09-07 | 2009-03-19 | Qlt Plug Delivery, Inc | Prostaglandin analogues for implant devices and methods |
WO2009035562A2 (en) | 2007-09-07 | 2009-03-19 | Qlt Plug Delivery, Inc | Drug cores for sustained release of therapeutic agents |
AU2008300022A1 (en) | 2007-09-07 | 2009-03-19 | Qlt Inc. | Lacrimal implant detection |
JP5528356B2 (ja) | 2008-02-18 | 2014-06-25 | キュー エル ティー インク. | 涙管インプラントおよび関連する方法 |
CN104623741A (zh) | 2008-04-30 | 2015-05-20 | 马缇医疗股份有限公司 | 复合泪管植入物及相关方法 |
AU2009244804A1 (en) | 2008-05-09 | 2009-11-12 | Qlt Inc. | Sustained release delivery of active agents to treat glaucoma and ocular hypertension |
EP2293912A1 (en) | 2008-05-30 | 2011-03-16 | QLT Plug Delivery, Inc. | Surface treated implantable articles and related methods |
TW201012469A (en) | 2008-06-24 | 2010-04-01 | Qlt Plug Delivery Inc | Combination treatment of glaucoma |
EP2328527A1 (en) | 2008-07-08 | 2011-06-08 | QLT Plug Delivery, Inc. | Lacrimal implant body including comforting agent |
CA2747556A1 (en) | 2008-12-19 | 2010-06-24 | Qlt Inc. | Substance delivering punctum implants and methods |
KR20110129869A (ko) | 2009-01-23 | 2011-12-02 | 큐엘티 인코포레이티드 | 하나 이상의 제제의 서방형 전달 |
WO2010096822A2 (en) | 2009-02-23 | 2010-08-26 | Qlt Plug Delivery, Inc. | Lacrimal implants and related methods |
-
2007
- 2007-04-02 DK DK07759961.1T patent/DK2010096T3/en active
- 2007-04-02 BR BRPI0709663-1A patent/BRPI0709663A2/pt not_active Application Discontinuation
- 2007-04-02 CN CN201310338528.5A patent/CN103393496B/zh active Active
- 2007-04-02 CN CN201310329155.5A patent/CN103393483B/zh active Active
- 2007-04-02 KR KR1020127008750A patent/KR101270113B1/ko active IP Right Grant
- 2007-04-02 ES ES07759961.1T patent/ES2640458T3/es active Active
- 2007-04-02 NZ NZ572193A patent/NZ572193A/en unknown
- 2007-04-02 RU RU2008143224/14A patent/RU2414199C2/ru active
- 2007-04-02 MX MX2008012601A patent/MX2008012601A/es not_active Application Discontinuation
- 2007-04-02 EP EP07759961.1A patent/EP2010096B1/en active Active
- 2007-04-02 EP EP07759964.5A patent/EP2004172B1/en active Active
- 2007-04-02 EP EP18199593.7A patent/EP3449873A1/en not_active Withdrawn
- 2007-04-02 JP JP2009503335A patent/JP5208916B2/ja active Active
- 2007-04-02 DK DK07759964.5T patent/DK2004172T3/en active
- 2007-04-02 KR KR1020087026758A patent/KR101062796B1/ko active IP Right Grant
- 2007-04-02 ES ES07759964T patent/ES2717607T3/es active Active
- 2007-04-02 WO PCT/US2007/065792 patent/WO2007115261A2/en active Application Filing
- 2007-04-02 KR KR1020087026781A patent/KR20090006153A/ko active Search and Examination
- 2007-04-02 SG SG201102311-6A patent/SG170816A1/en unknown
- 2007-04-02 KR KR1020117003795A patent/KR20110038144A/ko not_active Application Discontinuation
- 2007-04-02 CA CA2648421A patent/CA2648421C/en active Active
- 2007-04-02 US US11/695,545 patent/US7998497B2/en active Active
- 2007-04-02 RU RU2008143223/14A patent/RU2413480C2/ru active
- 2007-04-02 SG SG201102260-5A patent/SG170806A1/en unknown
- 2007-04-02 NZ NZ571758A patent/NZ571758A/en unknown
- 2007-04-02 CA CA2648066A patent/CA2648066C/en active Active
- 2007-04-02 US US11/695,537 patent/US8795711B2/en active Active
- 2007-04-02 NZ NZ595349A patent/NZ595349A/xx unknown
- 2007-04-02 JP JP2009503334A patent/JP2009532132A/ja active Pending
- 2007-04-02 BR BRPI0709672A patent/BRPI0709672B8/pt active IP Right Grant
- 2007-04-02 AU AU2007234445A patent/AU2007234445B2/en active Active
- 2007-04-02 MX MX2008012603A patent/MX2008012603A/es active IP Right Grant
- 2007-04-02 AU AU2007234447A patent/AU2007234447B2/en active Active
- 2007-04-02 NZ NZ595623A patent/NZ595623A/xx unknown
- 2007-04-02 WO PCT/US2007/065789 patent/WO2007115259A2/en active Application Filing
-
2008
- 2008-10-02 IL IL194514A patent/IL194514A0/en unknown
- 2008-10-02 ZA ZA200808401A patent/ZA200808401B/xx unknown
- 2008-10-02 IL IL194515A patent/IL194515A/en not_active IP Right Cessation
- 2008-10-13 NO NO20084275A patent/NO20084275L/no not_active Application Discontinuation
- 2008-10-21 ZA ZA200809003A patent/ZA200809003B/xx unknown
- 2008-10-23 NO NO20084471A patent/NO20084471L/no not_active Application Discontinuation
- 2008-12-10 US US12/332,219 patent/US20090092654A1/en not_active Abandoned
-
2010
- 2010-11-30 RU RU2010149066/14A patent/RU2010149066A/ru not_active Application Discontinuation
- 2010-12-03 RU RU2010149861/14A patent/RU2010149861A/ru not_active Application Discontinuation
-
2011
- 2011-04-03 IL IL212114A patent/IL212114A/en active IP Right Grant
- 2011-04-03 IL IL212113A patent/IL212113A/en active IP Right Grant
- 2011-07-18 US US13/184,690 patent/US8747884B2/en active Active
-
2012
- 2012-08-02 JP JP2012171816A patent/JP2012228571A/ja active Pending
- 2012-10-04 US US13/645,261 patent/US8691265B2/en active Active
-
2013
- 2013-04-18 IL IL225842A patent/IL225842B/en active IP Right Grant
- 2013-11-01 JP JP2013228144A patent/JP2014087650A/ja active Pending
-
2014
- 2014-02-14 US US14/180,592 patent/US9610194B2/en active Active
- 2014-04-29 US US14/265,071 patent/US9168222B2/en active Active
- 2014-04-30 HK HK14104157.5A patent/HK1190909A1/zh unknown
- 2014-04-30 HK HK14104156.6A patent/HK1190908A1/zh unknown
- 2014-07-16 US US14/333,349 patent/US20140328894A1/en not_active Abandoned
- 2014-07-24 JP JP2014150364A patent/JP6279421B2/ja active Active
-
2015
- 2015-01-16 US US14/598,262 patent/US20150224200A1/en not_active Abandoned
- 2015-09-18 US US14/858,555 patent/US9549852B2/en active Active
-
2016
- 2016-11-01 JP JP2016213964A patent/JP2017060789A/ja not_active Ceased
-
2017
- 2017-01-13 US US15/405,991 patent/US9849082B2/en active Active
- 2017-05-11 JP JP2017094500A patent/JP2017148605A/ja active Pending
- 2017-12-22 US US15/852,619 patent/US10383817B2/en active Active
-
2018
- 2018-05-11 JP JP2018091793A patent/JP2018187396A/ja active Pending
- 2018-10-23 US US16/168,335 patent/US11406592B2/en active Active
- 2018-10-23 US US16/168,554 patent/US10300014B2/en active Active
-
2019
- 2019-08-02 JP JP2019142914A patent/JP2019213885A/ja active Pending
- 2019-08-19 US US16/544,884 patent/US10874606B2/en active Active
-
2020
- 2020-12-24 US US17/133,980 patent/US20210212941A1/en active Pending
-
2021
- 2021-05-17 JP JP2021082984A patent/JP7273891B2/ja active Active
-
2022
- 2022-08-06 US US17/882,552 patent/US20230165791A1/en active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1190908A1 (zh) | 用於藥物治療的鼻淚引流系統植入物 | |
HK1213169A1 (zh) | 角膜植入物以及用於放置的方法和系統 | |
IL197316A0 (en) | Buprenophine-wafer for drug substitution therapy | |
EP2079414A4 (en) | SYSTEM FOR CHEMOHYPER THERMAL TREATMENT | |
IL197673A (en) | A system for controlled infusion of therapeutic agents | |
GB2442875B (en) | Regulated drug delivery system | |
ZA200903649B (en) | Devices and methods for ophthalmic drug delivery | |
IL287975A (en) | Skin care system | |
GB0602178D0 (en) | Therapeutic treatment | |
EP2083774A4 (en) | THERAPEUTIC INTRAVAGINAL DEVICES AND METHOD | |
EP2081520A4 (en) | MEDICAL IMPLANTS | |
EP1962750A4 (en) | ASPIRATION SYSTEM FOR OPHTHALMIC MEDICAL DEVICES | |
GB0618930D0 (en) | Medical implant | |
IL193597A0 (en) | Conjunctival tissue system | |
GB0608655D0 (en) | Therapeutic Treatment | |
EP2023900A4 (en) | DRUG DELIVERY SYSTEM WITH CONTROLLED DOSES | |
GB0715790D0 (en) | Drug combination for the treatment of sialorrhoea | |
EP2002777A4 (en) | MEDICAL SYSTEM | |
GB0610909D0 (en) | Therapeutic treatment | |
ZA200809004B (en) | Autodestructive transdermal therapeutic system | |
IL197125A0 (en) | Drug combinations for treating airway diseases | |
EP2236148A4 (en) | MEDIinic agent for HELICOBACTER treatment | |
PL2043792T3 (pl) | System do obróbki ciągłej | |
IL195618A0 (en) | Drug administration methods | |
GB0607153D0 (en) | Therapeutic Method |