ZA200702222B - Modified Fc molecules - Google Patents

Modified Fc molecules

Info

Publication number
ZA200702222B
ZA200702222B ZA200702222A ZA200702222A ZA200702222B ZA 200702222 B ZA200702222 B ZA 200702222B ZA 200702222 A ZA200702222 A ZA 200702222A ZA 200702222 A ZA200702222 A ZA 200702222A ZA 200702222 B ZA200702222 B ZA 200702222B
Authority
ZA
South Africa
Prior art keywords
molecules
modified
Prior art date
Application number
ZA200702222A
Other languages
English (en)
Inventor
Gegg Colin
Karen C Sitney
Xiong Fei
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of ZA200702222B publication Critical patent/ZA200702222B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/06—Anabolic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2318/00—Antibody mimetics or scaffolds
    • C07K2318/10—Immunoglobulin or domain(s) thereof as scaffolds for inserted non-Ig peptide sequences, e.g. for vaccination purposes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ZA200702222A 2004-09-24 2007-03-16 Modified Fc molecules ZA200702222B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US61268004P 2004-09-24 2004-09-24

Publications (1)

Publication Number Publication Date
ZA200702222B true ZA200702222B (en) 2009-04-29

Family

ID=35911109

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200702222A ZA200702222B (en) 2004-09-24 2007-03-16 Modified Fc molecules

Country Status (17)

Country Link
US (7) US7442778B2 (xx)
EP (1) EP1797127B1 (xx)
JP (1) JP5017116B2 (xx)
KR (1) KR100920282B1 (xx)
CN (1) CN101103045B (xx)
AU (1) AU2005289685B2 (xx)
BR (1) BRPI0516011A (xx)
CA (1) CA2580796C (xx)
DK (1) DK1797127T3 (xx)
EA (1) EA011879B1 (xx)
ES (1) ES2629397T3 (xx)
IL (1) IL182139A (xx)
MA (1) MA28989B1 (xx)
MX (1) MX2007003320A (xx)
SI (1) SI1797127T1 (xx)
WO (1) WO2006036834A2 (xx)
ZA (1) ZA200702222B (xx)

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CA2594356C (en) 2005-01-05 2018-07-17 F-Star Biotechnologische Forschungs- Und Entwicklungsges.M.B.H. Synthetic immunoglobulin domains with binding properties engineered in regions of the molecule different from the complementarity determining regions

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US20090286964A1 (en) 2009-11-19
US7655764B2 (en) 2010-02-02
EP1797127B1 (en) 2017-06-14
MA28989B1 (fr) 2007-11-01
DK1797127T3 (en) 2017-10-02
EA011879B1 (ru) 2009-06-30
IL182139A (en) 2014-05-28
AU2005289685A1 (en) 2006-04-06
CN101103045A (zh) 2008-01-09
CA2580796A1 (en) 2006-04-06
KR100920282B1 (ko) 2009-10-08
IL182139A0 (en) 2007-07-24
CN101103045B (zh) 2015-11-25
US7662931B2 (en) 2010-02-16
CA2580796C (en) 2013-03-26
US20090041768A1 (en) 2009-02-12
US20090022744A1 (en) 2009-01-22
US7750128B2 (en) 2010-07-06
US20090281286A1 (en) 2009-11-12
EP1797127A2 (en) 2007-06-20
US20090234104A1 (en) 2009-09-17
US7645861B2 (en) 2010-01-12
US7750127B2 (en) 2010-07-06
US20090012272A1 (en) 2009-01-08
MX2007003320A (es) 2007-05-18
US7442778B2 (en) 2008-10-28
SI1797127T1 (sl) 2017-09-29
WO2006036834A3 (en) 2006-06-29
AU2005289685B2 (en) 2009-07-16
JP5017116B2 (ja) 2012-09-05
US7655765B2 (en) 2010-02-02
JP2008514201A (ja) 2008-05-08
ES2629397T3 (es) 2017-08-09
US20060140934A1 (en) 2006-06-29
KR20070057975A (ko) 2007-06-07
EA200700623A1 (ru) 2007-12-28
BRPI0516011A (pt) 2008-08-19
WO2006036834A2 (en) 2006-04-06

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