ZA200208060B - Corynebacterium glutamicum genes encoding metabolic pathway proteins. - Google Patents
Corynebacterium glutamicum genes encoding metabolic pathway proteins. Download PDFInfo
- Publication number
- ZA200208060B ZA200208060B ZA200208060A ZA200208060A ZA200208060B ZA 200208060 B ZA200208060 B ZA 200208060B ZA 200208060 A ZA200208060 A ZA 200208060A ZA 200208060 A ZA200208060 A ZA 200208060A ZA 200208060 B ZA200208060 B ZA 200208060B
- Authority
- ZA
- South Africa
- Prior art keywords
- nucleic acid
- seq
- acid molecule
- metabolic pathway
- cell
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title claims abstract description 90
- 102000004169 proteins and genes Human genes 0.000 title claims abstract description 60
- 241000186226 Corynebacterium glutamicum Species 0.000 title claims abstract description 30
- 230000037353 metabolic pathway Effects 0.000 title claims description 78
- 150000007523 nucleic acids Chemical class 0.000 claims abstract description 70
- 108020004707 nucleic acids Proteins 0.000 claims abstract description 67
- 102000039446 nucleic acids Human genes 0.000 claims abstract description 67
- 238000004519 manufacturing process Methods 0.000 claims abstract description 33
- 238000000034 method Methods 0.000 claims abstract description 27
- 102000004196 processed proteins & peptides Human genes 0.000 claims abstract description 21
- 108090000765 processed proteins & peptides Proteins 0.000 claims abstract description 21
- 239000013604 expression vector Substances 0.000 claims abstract description 5
- 150000001413 amino acids Chemical class 0.000 claims description 46
- 239000002773 nucleotide Substances 0.000 claims description 36
- 125000003729 nucleotide group Chemical group 0.000 claims description 36
- 239000012847 fine chemical Substances 0.000 claims description 34
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims description 22
- 239000004472 Lysine Substances 0.000 claims description 22
- 229930182817 methionine Natural products 0.000 claims description 22
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 claims description 21
- 229920001184 polypeptide Polymers 0.000 claims description 20
- -1 IysC Proteins 0.000 claims description 16
- 244000005700 microbiome Species 0.000 claims description 16
- 241000186216 Corynebacterium Species 0.000 claims description 12
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- 210000004027 cell Anatomy 0.000 claims 24
- 241000186145 Corynebacterium ammoniagenes Species 0.000 claims 2
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- 101100378010 Bacillus subtilis (strain 168) accC1 gene Proteins 0.000 claims 1
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- 235000012539 Bacterium linens Nutrition 0.000 claims 1
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- 241001517047 Corynebacterium acetoacidophilum Species 0.000 claims 1
- 101100465553 Dictyostelium discoideum psmB6 gene Proteins 0.000 claims 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18797000P | 2000-03-09 | 2000-03-09 | |
US60674000A | 2000-06-23 | 2000-06-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200208060B true ZA200208060B (en) | 2003-11-10 |
Family
ID=26883605
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200208060A ZA200208060B (en) | 2000-03-09 | 2002-10-08 | Corynebacterium glutamicum genes encoding metabolic pathway proteins. |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP1261718B1 (pt) |
JP (1) | JP4786107B2 (pt) |
KR (1) | KR101012231B1 (pt) |
CN (2) | CN101255431B (pt) |
AT (1) | ATE486941T1 (pt) |
AU (2) | AU2001223903B2 (pt) |
BR (1) | BRPI0017148B1 (pt) |
CA (1) | CA2402186C (pt) |
DE (1) | DE60045191D1 (pt) |
DK (1) | DK1261718T3 (pt) |
ES (1) | ES2354867T3 (pt) |
MX (1) | MXPA02008710A (pt) |
WO (1) | WO2001066573A2 (pt) |
ZA (1) | ZA200208060B (pt) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10109685A1 (de) * | 2000-09-09 | 2002-04-11 | Degussa | Neue für das sahH-Gen kodierende Nukleotidsequenzen |
EP1315820B1 (en) * | 2000-09-09 | 2005-09-14 | Degussa AG | Nucleotide sequences which code for s-adenosyl homocysteinase (sahh) |
US6759224B2 (en) | 2000-09-09 | 2004-07-06 | Degussa Ag | Nucleotide sequences which code for the sahH gene |
DE10154292A1 (de) * | 2001-11-05 | 2003-05-15 | Basf Ag | Gene die für Stoffwechselweg-Proteine codieren |
DE10162729A1 (de) * | 2001-12-20 | 2003-07-03 | Degussa | Allele des sigA-Gens aus coryneformen Bakterien |
DE10222858A1 (de) * | 2002-05-23 | 2003-12-04 | Basf Ag | Verfahren zur fermentativen Herstellung schwefelhaltiger Feinchemikalien |
EP2064321B1 (en) * | 2006-08-30 | 2016-03-09 | Cargill, Incorporated | Beta-alanine/alpha-ketoglutarate aminotransferase for 3-hydroxypropionic acid production |
KR100830289B1 (ko) * | 2007-01-18 | 2008-05-16 | 씨제이제일제당 (주) | L-아르기닌 생산 변이주 및 이의 제조방법 |
KR100987281B1 (ko) | 2008-01-31 | 2010-10-12 | 씨제이제일제당 (주) | 개량된 프로모터 및 이를 이용한 l-라이신의 생산 방법 |
US8404465B2 (en) | 2009-03-11 | 2013-03-26 | Celexion, Llc | Biological synthesis of 6-aminocaproic acid from carbohydrate feedstocks |
EP2885400A1 (en) | 2012-08-17 | 2015-06-24 | Celexion, LLC | Biological synthesis of difunctional hexanes and pentanes from carbohydrate feedstocks |
CN104561194A (zh) * | 2013-10-16 | 2015-04-29 | 南京工业大学 | 一种n-乙酰神经氨酸醛缩酶在催化合成n-乙酰神经氨酸中的应用 |
CN103805552B (zh) * | 2014-02-19 | 2016-03-23 | 中国科学院天津工业生物技术研究所 | 一株生物合成稀少糖的谷氨酸棒杆菌工程菌株及其构建方法和应用 |
CN104535511A (zh) * | 2014-07-04 | 2015-04-22 | 陶淑芳 | 基于单酶反应的l-谷氨酰胺的比色测定方法以及测定试剂盒 |
JP2019531759A (ja) | 2016-10-26 | 2019-11-07 | 味の素株式会社 | 目的物質の製造方法 |
EP3532628B1 (en) * | 2016-10-26 | 2024-02-28 | Ajinomoto Co., Inc. | Method for producing objective substance |
EP3456833A1 (en) * | 2017-09-18 | 2019-03-20 | Evonik Degussa GmbH | Method for the fermentative production of l-amino acids |
CN112251457B (zh) * | 2019-07-22 | 2022-04-15 | 江南大学 | 一种4-羟基异亮氨酸生产菌的适应性进化方法及其应用 |
CN111607601B (zh) * | 2020-04-24 | 2022-10-18 | 天津大学 | 谷氨酸棒杆菌转录调控因子IpsA突变体及应用 |
CN112812985B (zh) * | 2020-11-11 | 2023-01-10 | 新疆阜丰生物科技有限公司 | 一种提高谷氨酰胺发酵产酸的方法 |
KR102281366B1 (ko) * | 2021-01-26 | 2021-07-22 | 씨제이제일제당 (주) | 신규한 테트라하이드로디피콜리네이트 n-숙시닐트랜스퍼라제 변이체 및 이를 이용한 l-발린 생산 방법 |
KR102303747B1 (ko) * | 2021-04-12 | 2021-09-16 | 씨제이제일제당 (주) | 신규한 주요 촉진제 수퍼패밀리 퍼미에이즈 변이체 및 이를 이용한 l-라이신 생산 방법 |
CN114410614A (zh) * | 2021-12-30 | 2022-04-29 | 宁夏伊品生物科技股份有限公司 | Yh66_05415蛋白或其突变体在制备l-精氨酸中的应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5540240B1 (pt) * | 1970-02-06 | 1980-10-16 | ||
JP4075087B2 (ja) * | 1996-12-05 | 2008-04-16 | 味の素株式会社 | L−リジンの製造法 |
SK18862001A3 (sk) * | 1999-06-25 | 2002-11-06 | Basf Aktiengesellschaft | Gény Corynebacterium glutamicum kódujúce proteíny metabolických dráh |
JP4623825B2 (ja) * | 1999-12-16 | 2011-02-02 | 協和発酵バイオ株式会社 | 新規ポリヌクレオチド |
-
2000
- 2000-12-22 AT AT00987602T patent/ATE486941T1/de not_active IP Right Cessation
- 2000-12-22 KR KR1020027011741A patent/KR101012231B1/ko not_active IP Right Cessation
- 2000-12-22 CN CN2008100909127A patent/CN101255431B/zh not_active Expired - Fee Related
- 2000-12-22 AU AU2001223903A patent/AU2001223903B2/en not_active Ceased
- 2000-12-22 MX MXPA02008710A patent/MXPA02008710A/es active IP Right Grant
- 2000-12-22 BR BRPI0017148A patent/BRPI0017148B1/pt not_active IP Right Cessation
- 2000-12-22 EP EP00987602A patent/EP1261718B1/en not_active Expired - Lifetime
- 2000-12-22 WO PCT/IB2000/002035 patent/WO2001066573A2/en active Application Filing
- 2000-12-22 CN CN00819506A patent/CN1452659A/zh active Pending
- 2000-12-22 ES ES00987602T patent/ES2354867T3/es not_active Expired - Lifetime
- 2000-12-22 JP JP2001565737A patent/JP4786107B2/ja not_active Expired - Fee Related
- 2000-12-22 DK DK00987602.0T patent/DK1261718T3/da active
- 2000-12-22 CA CA2402186A patent/CA2402186C/en not_active Expired - Fee Related
- 2000-12-22 AU AU2390301A patent/AU2390301A/xx active Pending
- 2000-12-22 DE DE60045191T patent/DE60045191D1/de not_active Expired - Lifetime
-
2002
- 2002-10-08 ZA ZA200208060A patent/ZA200208060B/en unknown
Also Published As
Publication number | Publication date |
---|---|
CN101255431B (zh) | 2012-05-16 |
JP4786107B2 (ja) | 2011-10-05 |
MXPA02008710A (es) | 2003-02-24 |
KR20020086616A (ko) | 2002-11-18 |
CN101255431A (zh) | 2008-09-03 |
BR0017148A (pt) | 2003-03-11 |
ATE486941T1 (de) | 2010-11-15 |
CN1452659A (zh) | 2003-10-29 |
CA2402186C (en) | 2011-04-05 |
EP1261718A2 (en) | 2002-12-04 |
AU2390301A (en) | 2001-09-17 |
JP2003525623A (ja) | 2003-09-02 |
BRPI0017148B1 (pt) | 2016-03-01 |
KR101012231B1 (ko) | 2011-02-09 |
DE60045191D1 (de) | 2010-12-16 |
ES2354867T3 (es) | 2011-03-18 |
AU2001223903B2 (en) | 2006-11-02 |
DK1261718T3 (da) | 2011-02-14 |
WO2001066573A2 (en) | 2001-09-13 |
WO2001066573A3 (en) | 2002-05-10 |
EP1261718B1 (en) | 2010-11-03 |
CA2402186A1 (en) | 2001-09-13 |
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