ZA200206963B - Fast dissolving orally consumable films containing an ion exchange resin as a taste masking agent. - Google Patents
Fast dissolving orally consumable films containing an ion exchange resin as a taste masking agent. Download PDFInfo
- Publication number
- ZA200206963B ZA200206963B ZA200206963A ZA200206963A ZA200206963B ZA 200206963 B ZA200206963 B ZA 200206963B ZA 200206963 A ZA200206963 A ZA 200206963A ZA 200206963 A ZA200206963 A ZA 200206963A ZA 200206963 B ZA200206963 B ZA 200206963B
- Authority
- ZA
- South Africa
- Prior art keywords
- film according
- ion exchange
- exchange resin
- agent
- consumable film
- Prior art date
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- 239000003456 ion exchange resin Substances 0.000 title claims description 27
- 229920003303 ion-exchange polymer Polymers 0.000 title claims description 27
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- 239000006068 taste-masking agent Substances 0.000 title claims description 13
- 239000013543 active substance Substances 0.000 claims description 22
- 239000000203 mixture Substances 0.000 claims description 21
- MYRTYDVEIRVNKP-UHFFFAOYSA-N 1,2-Divinylbenzene Chemical compound C=CC1=CC=CC=C1C=C MYRTYDVEIRVNKP-UHFFFAOYSA-N 0.000 claims description 15
- 229920000642 polymer Polymers 0.000 claims description 15
- 239000011347 resin Substances 0.000 claims description 13
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- 229920001218 Pullulan Polymers 0.000 claims description 11
- 239000000499 gel Substances 0.000 claims description 11
- 235000019423 pullulan Nutrition 0.000 claims description 11
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 8
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- 229960000938 nalorphine Drugs 0.000 description 1
- UZHSEJADLWPNLE-GRGSLBFTSA-N naloxone Chemical compound O=C([C@@H]1O2)CC[C@@]3(O)[C@H]4CC5=CC=C(O)C2=C5[C@@]13CCN4CC=C UZHSEJADLWPNLE-GRGSLBFTSA-N 0.000 description 1
- 229960004127 naloxone Drugs 0.000 description 1
- DQCKKXVULJGBQN-XFWGSAIBSA-N naltrexone Chemical compound N1([C@@H]2CC3=CC=C(C=4O[C@@H]5[C@](C3=4)([C@]2(CCC5=O)O)CC1)O)CC1CC1 DQCKKXVULJGBQN-XFWGSAIBSA-N 0.000 description 1
- 229960003086 naltrexone Drugs 0.000 description 1
- 229960002715 nicotine Drugs 0.000 description 1
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 description 1
- 229940071266 nicotine 2 mg Drugs 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229960005118 oxymorphone Drugs 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 239000008177 pharmaceutical agent Substances 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 229960003396 phenacemide Drugs 0.000 description 1
- 229960003893 phenacetin Drugs 0.000 description 1
- 229960000964 phenelzine Drugs 0.000 description 1
- 229960003877 pheneturide Drugs 0.000 description 1
- 229960002695 phenobarbital Drugs 0.000 description 1
- DDBREPKUVSBGFI-UHFFFAOYSA-N phenobarbital Chemical compound C=1C=CC=CC=1C1(CC)C(=O)NC(=O)NC1=O DDBREPKUVSBGFI-UHFFFAOYSA-N 0.000 description 1
- 229960004227 phensuximide Drugs 0.000 description 1
- 229960002895 phenylbutazone Drugs 0.000 description 1
- VYMDGNCVAMGZFE-UHFFFAOYSA-N phenylbutazonum Chemical compound O=C1C(CCCC)C(=O)N(C=2C=CC=CC=2)N1C1=CC=CC=C1 VYMDGNCVAMGZFE-UHFFFAOYSA-N 0.000 description 1
- 229940021213 phenylephrine hydrochloride 10 mg Drugs 0.000 description 1
- VJKUPQSHOVKBCO-AHMKVGDJSA-N picrotoxin Chemical compound O=C([C@@]12O[C@@H]1C[C@]1(O)[C@@]32C)O[C@@H]3[C@H]2[C@@H](C(=C)C)[C@@H]1C(=O)O2.O=C([C@@]12O[C@@H]1C[C@]1(O)[C@@]32C)O[C@@H]3[C@H]2[C@@H](C(C)(O)C)[C@@H]1C(=O)O2 VJKUPQSHOVKBCO-AHMKVGDJSA-N 0.000 description 1
- 229920001467 poly(styrenesulfonates) Polymers 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 229960002796 polystyrene sulfonate Drugs 0.000 description 1
- 239000011970 polystyrene sulfonate Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 150000003141 primary amines Chemical class 0.000 description 1
- DQMZLTXERSFNPB-UHFFFAOYSA-N primidone Chemical compound C=1C=CC=CC=1C1(CC)C(=O)NCNC1=O DQMZLTXERSFNPB-UHFFFAOYSA-N 0.000 description 1
- 229960002393 primidone Drugs 0.000 description 1
- 229960003447 pseudoephedrine hydrochloride Drugs 0.000 description 1
- BALXUFOVQVENIU-KXNXZCPBSA-N pseudoephedrine hydrochloride Chemical compound [H+].[Cl-].CN[C@@H](C)[C@@H](O)C1=CC=CC=C1 BALXUFOVQVENIU-KXNXZCPBSA-N 0.000 description 1
- 229940021228 pseudoephedrine hydrochloride 30 mg Drugs 0.000 description 1
- 229960004159 pseudoephedrine sulfate Drugs 0.000 description 1
- 230000001003 psychopharmacologic effect Effects 0.000 description 1
- BJOIZNZVOZKDIG-MDEJGZGSSA-N reserpine Chemical compound O([C@H]1[C@@H]([C@H]([C@H]2C[C@@H]3C4=C([C]5C=CC(OC)=CC5=N4)CCN3C[C@H]2C1)C(=O)OC)OC)C(=O)C1=CC(OC)=C(OC)C(OC)=C1 BJOIZNZVOZKDIG-MDEJGZGSSA-N 0.000 description 1
- 229960003147 reserpine Drugs 0.000 description 1
- MDMGHDFNKNZPAU-UHFFFAOYSA-N roserpine Natural products C1C2CN3CCC(C4=CC=C(OC)C=C4N4)=C4C3CC2C(OC(C)=O)C(OC)C1OC(=O)C1=CC(OC)=C(OC)C(OC)=C1 MDMGHDFNKNZPAU-UHFFFAOYSA-N 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 150000003440 styrenes Chemical class 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 229960002573 sultiame Drugs 0.000 description 1
- KQKPFRSPSRPDEB-UHFFFAOYSA-N sumatriptan Chemical compound CNS(=O)(=O)CC1=CC=C2NC=C(CCN(C)C)C2=C1 KQKPFRSPSRPDEB-UHFFFAOYSA-N 0.000 description 1
- 229960000658 sumatriptan succinate Drugs 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000013268 sustained release Methods 0.000 description 1
- 239000012730 sustained-release form Substances 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- LLPOLZWFYMWNKH-UHFFFAOYSA-N trans-dihydrocodeinone Natural products C1C(N(CCC234)C)C2CCC(=O)C3OC2=C4C1=CC=C2OC LLPOLZWFYMWNKH-UHFFFAOYSA-N 0.000 description 1
- 229960003741 tranylcypromine Drugs 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- IRYJRGCIQBGHIV-UHFFFAOYSA-N trimethadione Chemical compound CN1C(=O)OC(C)(C)C1=O IRYJRGCIQBGHIV-UHFFFAOYSA-N 0.000 description 1
- 229960004453 trimethadione Drugs 0.000 description 1
- 229940109253 triprolidine hydrochloride 2.5 mg Drugs 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- 150000003752 zinc compounds Chemical class 0.000 description 1
- 229940102192 zolmitriptan 2.5 mg Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7007—Drug-containing films, membranes or sheets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
- A61K47/585—Ion exchange resins, e.g. polystyrene sulfonic acid resin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Zoology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/535,005 US7067116B1 (en) | 2000-03-23 | 2000-03-23 | Fast dissolving orally consumable solid film containing a taste masking agent and pharmaceutically active agent at weight ratio of 1:3 to 3:1 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200206963B true ZA200206963B (en) | 2003-07-21 |
Family
ID=24132458
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200206963A ZA200206963B (en) | 2000-03-23 | 2002-08-29 | Fast dissolving orally consumable films containing an ion exchange resin as a taste masking agent. |
Country Status (37)
| Country | Link |
|---|---|
| US (2) | US7067116B1 (de) |
| EP (2) | EP1674078A3 (de) |
| JP (1) | JP4145048B2 (de) |
| KR (1) | KR20020084233A (de) |
| CN (2) | CN1181814C (de) |
| AP (1) | AP2002002648A0 (de) |
| AR (1) | AR029494A1 (de) |
| AT (1) | ATE324864T1 (de) |
| AU (3) | AU2972001A (de) |
| BR (1) | BR0109378A (de) |
| CA (1) | CA2402988C (de) |
| CO (1) | CO5280057A1 (de) |
| CR (1) | CR6740A (de) |
| CZ (1) | CZ20023108A3 (de) |
| DE (1) | DE60119298T2 (de) |
| DK (1) | DK1267829T3 (de) |
| ES (1) | ES2261455T3 (de) |
| GT (1) | GT200100043A (de) |
| HK (1) | HK1052880A1 (de) |
| HU (1) | HUP0300035A2 (de) |
| IL (2) | IL151568A0 (de) |
| IS (1) | IS6523A (de) |
| MX (1) | MXPA02008425A (de) |
| NO (1) | NO20024513D0 (de) |
| NZ (1) | NZ520961A (de) |
| PA (1) | PA8513901A1 (de) |
| PE (1) | PE20011135A1 (de) |
| PL (1) | PL357135A1 (de) |
| PT (1) | PT1267829E (de) |
| RU (1) | RU2256442C2 (de) |
| SK (1) | SK13432002A3 (de) |
| SV (1) | SV2001000345A (de) |
| TW (1) | TWI290474B (de) |
| UY (1) | UY26628A1 (de) |
| WO (1) | WO2001070194A1 (de) |
| YU (1) | YU71502A (de) |
| ZA (1) | ZA200206963B (de) |
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| US5968547A (en) | 1997-02-24 | 1999-10-19 | Euro-Celtique, S.A. | Method of providing sustained analgesia with buprenorphine |
| US20030206942A1 (en) * | 1998-09-25 | 2003-11-06 | Neema Kulkarni | Fast dissolving orally consumable films containing an antitussive and a mucosa coating agent |
| US6596298B2 (en) * | 1998-09-25 | 2003-07-22 | Warner-Lambert Company | Fast dissolving orally comsumable films |
| US7713566B2 (en) | 1999-12-21 | 2010-05-11 | Zapp Loretta M | Method for enhancing post-processing content of beneficial compounds in beverages |
| US6391886B1 (en) * | 2000-12-04 | 2002-05-21 | The Procter & Gamble Company | Oral compositions having improved consumer aesthetics |
| US20030003212A1 (en) | 2001-06-13 | 2003-01-02 | Givaudan Sa | Taste modifiers |
| US20110033542A1 (en) | 2009-08-07 | 2011-02-10 | Monosol Rx, Llc | Sublingual and buccal film compositions |
| US8663687B2 (en) | 2001-10-12 | 2014-03-04 | Monosol Rx, Llc | Film compositions for delivery of actives |
| US8765167B2 (en) | 2001-10-12 | 2014-07-01 | Monosol Rx, Llc | Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions |
| US11207805B2 (en) | 2001-10-12 | 2021-12-28 | Aquestive Therapeutics, Inc. | Process for manufacturing a resulting pharmaceutical film |
| EP1463490B1 (de) * | 2001-10-12 | 2011-12-14 | MonoSolRX, LLC | Auf glucan-film basierte wirkstoffverabreichungssysteme |
| US20190328679A1 (en) | 2001-10-12 | 2019-10-31 | Aquestive Therapeutics, Inc. | Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions |
| US8900498B2 (en) | 2001-10-12 | 2014-12-02 | Monosol Rx, Llc | Process for manufacturing a resulting multi-layer pharmaceutical film |
| US8603514B2 (en) | 2002-04-11 | 2013-12-10 | Monosol Rx, Llc | Uniform films for rapid dissolve dosage form incorporating taste-masking compositions |
| US7666337B2 (en) | 2002-04-11 | 2010-02-23 | Monosol Rx, Llc | Polyethylene oxide-based films and drug delivery systems made therefrom |
| US7425292B2 (en) | 2001-10-12 | 2008-09-16 | Monosol Rx, Llc | Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom |
| US20070281003A1 (en) | 2001-10-12 | 2007-12-06 | Fuisz Richard C | Polymer-Based Films and Drug Delivery Systems Made Therefrom |
| US10285910B2 (en) | 2001-10-12 | 2019-05-14 | Aquestive Therapeutics, Inc. | Sublingual and buccal film compositions |
| US7357891B2 (en) | 2001-10-12 | 2008-04-15 | Monosol Rx, Llc | Process for making an ingestible film |
| US8900497B2 (en) | 2001-10-12 | 2014-12-02 | Monosol Rx, Llc | Process for making a film having a substantially uniform distribution of components |
| AU2002362772B2 (en) * | 2001-10-12 | 2007-09-06 | Aquestive Therapeutics, Inc. | Uniform films for rapid dissolve dosage form incorporating taste-masking compositions |
| GB2380936B (en) * | 2001-10-18 | 2003-07-09 | Reckitt Benckiser Healthcare | Improvements in or relating to compositions |
| MXPA02011337A (es) * | 2001-11-16 | 2003-05-26 | Nat Starch Chem Invest | Peliculas que contienen almidon. |
| WO2003054077A1 (en) | 2001-12-11 | 2003-07-03 | Ceapro Inc. | Cereal beta glucan compositions, methods of preparation and uses thereof |
| DE10207394B4 (de) | 2002-02-21 | 2007-03-29 | Lts Lohmann Therapie-Systeme Ag | Geschmacksmaskierte oblatenförmige Arzneizubereitung |
| US8017150B2 (en) | 2002-04-11 | 2011-09-13 | Monosol Rx, Llc | Polyethylene oxide-based films and drug delivery systems made therefrom |
| CN1662147A (zh) * | 2002-04-16 | 2005-08-31 | 怀泰斯德美国有限公司 | 功能性成分的传递系统 |
| CN1747656B (zh) * | 2002-07-22 | 2011-05-04 | 莫诺索尔克斯有限公司 | 速溶剂型的包装和分配 |
| GB0217382D0 (en) * | 2002-07-26 | 2002-09-04 | Pfizer Ltd | Process for making orally consumable dosage forms |
| AU2002950426A0 (en) * | 2002-07-29 | 2002-09-12 | Patrick John Shanahan | Anti microbial oro-dental system |
| AU2003281744B2 (en) * | 2002-07-29 | 2005-03-10 | Patrick John Shanahan | Oral and dental composition |
| US6916463B2 (en) | 2002-09-24 | 2005-07-12 | The Procter & Gamble Company | Oral products having an aesthetic layer |
| CA2504610C (en) * | 2002-11-12 | 2012-02-21 | Elan Pharma International Ltd. | Fast-disintegrating solid dosage forms being not friable and comprising pullulan |
| US9561182B2 (en) * | 2003-08-22 | 2017-02-07 | Cure Pharmaceutical Corporation | Edible films for administration of medicaments to animals, methods for their manufacture and methods for their use for the treatment of animals |
| AU2003295577A1 (en) * | 2002-11-14 | 2004-06-15 | Zengen, Inc. | Edible film for relief of cough or symptoms associated with pharyngitis |
| US8999372B2 (en) * | 2002-11-14 | 2015-04-07 | Cure Pharmaceutical Corporation | Methods for modulating dissolution, bioavailability, bioequivalence and drug delivery profile of thin film drug delivery systems, controlled-release thin film dosage formats, and methods for their manufacture and use |
| US20040191302A1 (en) * | 2003-03-28 | 2004-09-30 | Davidson Robert S. | Method and apparatus for minimizing heat, moisture, and shear damage to medicants and other compositions during incorporation of same with edible films |
| US20040131662A1 (en) * | 2003-11-12 | 2004-07-08 | Davidson Robert S. | Method and apparatus for minimizing heat, moisture, and shear damage to medicants and other compositions during incorporation of same with edible films |
| WO2004058231A2 (en) * | 2002-12-26 | 2004-07-15 | University Of Manitoba | Dissolving film comprising a therapeutically active agent within the film or in a pouch formed by the film |
| US20040180110A1 (en) | 2003-03-14 | 2004-09-16 | Atul Mistry | Chewing gum and confectionery compositions containing an endothermic agent |
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| US20040202698A1 (en) * | 2003-04-02 | 2004-10-14 | The Procter & Gamble Company | Drug delivery systems comprising an encapsulated active ingredient |
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-
2000
- 2000-03-23 US US09/535,005 patent/US7067116B1/en not_active Expired - Fee Related
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2001
- 2001-01-23 HU HU0300035A patent/HUP0300035A2/hu unknown
- 2001-01-23 WO PCT/US2001/002192 patent/WO2001070194A1/en active Application Filing
- 2001-01-23 YU YU71502A patent/YU71502A/sh unknown
- 2001-01-23 NZ NZ520961A patent/NZ520961A/en not_active IP Right Cessation
- 2001-01-23 SK SK1343-2002A patent/SK13432002A3/sk unknown
- 2001-01-23 PL PL01357135A patent/PL357135A1/xx not_active Application Discontinuation
- 2001-01-23 MX MXPA02008425A patent/MXPA02008425A/es active IP Right Grant
- 2001-01-23 JP JP2001568392A patent/JP4145048B2/ja not_active Expired - Fee Related
- 2001-01-23 AU AU2972001A patent/AU2972001A/xx active Pending
- 2001-01-23 CZ CZ20023108A patent/CZ20023108A3/cs unknown
- 2001-01-23 ES ES01959912T patent/ES2261455T3/es not_active Expired - Lifetime
- 2001-01-23 EP EP06007766A patent/EP1674078A3/de not_active Withdrawn
- 2001-01-23 DE DE60119298T patent/DE60119298T2/de not_active Expired - Lifetime
- 2001-01-23 BR BR0109378-9A patent/BR0109378A/pt not_active Application Discontinuation
- 2001-01-23 CN CNB018069983A patent/CN1181814C/zh not_active Expired - Fee Related
- 2001-01-23 EP EP01959912A patent/EP1267829B1/de not_active Revoked
- 2001-01-23 RU RU2002128354/15A patent/RU2256442C2/ru not_active IP Right Cessation
- 2001-01-23 AT AT01959912T patent/ATE324864T1/de not_active IP Right Cessation
- 2001-01-23 PT PT01959912T patent/PT1267829E/pt unknown
- 2001-01-23 CA CA002402988A patent/CA2402988C/en not_active Expired - Fee Related
- 2001-01-23 AP APAP/P/2002/002648A patent/AP2002002648A0/en unknown
- 2001-01-23 KR KR1020027012429A patent/KR20020084233A/ko not_active Application Discontinuation
- 2001-01-23 AU AU2001229720A patent/AU2001229720B2/en not_active Ceased
- 2001-01-23 IL IL15156801A patent/IL151568A0/xx active IP Right Grant
- 2001-01-23 CN CNB2004101003959A patent/CN100525835C/zh not_active Expired - Fee Related
- 2001-01-23 DK DK01959912T patent/DK1267829T3/da active
- 2001-02-07 TW TW090102651A patent/TWI290474B/zh not_active IP Right Cessation
- 2001-03-15 SV SV2001000345A patent/SV2001000345A/es not_active Application Discontinuation
- 2001-03-21 CO CO01022573A patent/CO5280057A1/es active IP Right Grant
- 2001-03-21 GT GT200100043A patent/GT200100043A/es unknown
- 2001-03-21 PE PE2001000261A patent/PE20011135A1/es not_active Application Discontinuation
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- 2001-03-21 UY UY26628A patent/UY26628A1/es not_active Application Discontinuation
- 2001-03-22 AR ARP010101341A patent/AR029494A1/es unknown
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2002
- 2002-08-23 IS IS6523A patent/IS6523A/is unknown
- 2002-08-27 CR CR6740A patent/CR6740A/es not_active Application Discontinuation
- 2002-08-29 ZA ZA200206963A patent/ZA200206963B/en unknown
- 2002-09-20 NO NO20024513A patent/NO20024513D0/no not_active Application Discontinuation
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2003
- 2003-07-17 HK HK03105167.3A patent/HK1052880A1/zh unknown
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2006
- 2006-05-04 AU AU2006201888A patent/AU2006201888B2/en not_active Ceased
- 2006-05-05 US US11/429,547 patent/US7648712B2/en not_active Expired - Fee Related
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2011
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