UY29167A1 - Pirimidinas como antagonistas del receptor de prostaglandina d2 - Google Patents

Pirimidinas como antagonistas del receptor de prostaglandina d2

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Publication number
UY29167A1
UY29167A1 UY29167A UY29167A UY29167A1 UY 29167 A1 UY29167 A1 UY 29167A1 UY 29167 A UY29167 A UY 29167A UY 29167 A UY29167 A UY 29167A UY 29167 A1 UY29167 A1 UY 29167A1
Authority
UY
Uruguay
Prior art keywords
receptor
prostaglandina
pyrimidins
antagonists
allergic
Prior art date
Application number
UY29167A
Other languages
English (en)
Inventor
Charles J Gardner
David W Stefany
Lim Sungtaek
Keith John Harris
Bin Cao
Ray Boffey
Timothy Gillespy
Joacy Aguiar
Hazel Joan Dyke
Elsa Amandine Dechaux
Original Assignee
Aventis Pharma Inc
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Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Publication of UY29167A1 publication Critical patent/UY29167A1/es

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    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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    • A61K31/50Pyridazines; Hydrogenated pyridazines
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    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Compuesto de Piridiminas de Fórmula (I) en los que Cy1, Cy2, L1, L2 y R1 son como se definen en la Memoria Descriptiva, su preparación y las composición farmacéutica que los comprenden, para tratar estados de enfermedad que pueden modularse por la inhibición del recpetor PGD2, tales como asma bronquial, enfermedad pulmonar obstructiva crónica (COPD), rinitis alérgica, dermatitis alérgica, conjuntivitis alérgica, bronquitis, mastocitosis sistémica y lesión de reperfusión isquémica.
UY29167A 2004-10-15 2005-10-14 Pirimidinas como antagonistas del receptor de prostaglandina d2 UY29167A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US61927204P 2004-10-15 2004-10-15

Publications (1)

Publication Number Publication Date
UY29167A1 true UY29167A1 (es) 2006-05-31

Family

ID=36072155

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Application Number Title Priority Date Filing Date
UY29167A UY29167A1 (es) 2004-10-15 2005-10-14 Pirimidinas como antagonistas del receptor de prostaglandina d2

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US (2) US8193183B2 (es)
EP (1) EP1891019B1 (es)
JP (1) JP4970274B2 (es)
KR (1) KR101280268B1 (es)
CN (1) CN101039920B (es)
AR (1) AR053770A1 (es)
AU (1) AU2005295502B2 (es)
BR (1) BRPI0516482A (es)
CA (1) CA2583742C (es)
CR (1) CR9003A (es)
DK (1) DK1891019T3 (es)
EC (1) ECSP077398A (es)
ES (1) ES2392091T3 (es)
GT (1) GT200500284A (es)
HK (1) HK1108429A1 (es)
HN (1) HN2005000795A (es)
IL (1) IL182090A (es)
MA (1) MA29071B1 (es)
MX (1) MX2007003155A (es)
MY (2) MY142453A (es)
NO (1) NO339772B1 (es)
NZ (1) NZ553919A (es)
PA (1) PA8649801A1 (es)
PE (1) PE20060936A1 (es)
PL (1) PL1891019T3 (es)
PT (1) PT1891019E (es)
RU (1) RU2417990C2 (es)
SG (1) SG156653A1 (es)
SI (1) SI1891019T1 (es)
SV (1) SV2006002272A (es)
TN (1) TNSN07098A1 (es)
TW (1) TWI372751B (es)
UA (1) UA88485C2 (es)
UY (1) UY29167A1 (es)
WO (1) WO2006044732A2 (es)
ZA (1) ZA200702209B (es)

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AU2008232771B2 (en) * 2007-03-30 2012-12-20 Sanofi-Aventis Pyrimidine hydrazide compounds as PGDS inhibitors
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EP2014657A1 (de) * 2007-06-21 2009-01-14 Bayer Schering Pharma Aktiengesellschaft Diaminopyrimidine als Modulatoren des EP2-Rezeptors
JP2010532366A (ja) 2007-06-29 2010-10-07 サノフィ−アベンティス 2−(3−{6−[2−(2,4−ジクロロフェニル)−エチルアミノ]−2−メトキシピリミジン−4−イル}−フェニル)−2−メチルプロピオン酸を製造する新しい方法
AU2008282728B2 (en) * 2007-08-02 2012-04-19 Amgen Inc. Pl3 kinase modulators and methods of use
WO2009055730A1 (en) * 2007-10-25 2009-04-30 Genentech, Inc. Process for making thienopyrimidine compounds
BRPI0817135A2 (pt) * 2007-11-06 2014-10-07 Du Pont Composto, método de controle de doenças de plantas e composições fungicidas
CA2710194C (en) 2007-12-19 2014-04-22 Amgen Inc. Inhibitors of p13 kinase
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CA2714743C (en) 2008-02-19 2017-01-17 Janssen Pharmaceutica N.V. Aryl-hydroxyethylamino-pyrimidines and triazines as modulators of fatty acid amide hydrolase
WO2009127949A1 (en) * 2008-04-17 2009-10-22 Pfizer Inc. 4- [3- (aryloxy) benzylidene] -3-methyl piperidine aryl carboxamide compounds useful as faah inhibitors
GB2463788B (en) * 2008-09-29 2010-12-15 Amira Pharmaceuticals Inc Heteroaryl antagonists of prostaglandin D2 receptors
UY32251A (es) * 2008-11-20 2010-05-31 Glaxosmithkline Llc Compuestos quimicos
AR074776A1 (es) * 2008-12-18 2011-02-09 Sanofi Aventis Metodo para tratar la degeneracion macular; modulando el sistema inmunitario del paciente
WO2011022348A1 (en) 2009-08-18 2011-02-24 Janssen Pharmaceutica Nv Ethylene diamine modulators of fatty acid amide hydrolase
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