EA200802417A1 - Замещенные фенилуксусные кислоты как dp-2-антагонисты - Google Patents

Замещенные фенилуксусные кислоты как dp-2-антагонисты

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Publication number
EA200802417A1
EA200802417A1 EA200802417A EA200802417A EA200802417A1 EA 200802417 A1 EA200802417 A1 EA 200802417A1 EA 200802417 A EA200802417 A EA 200802417A EA 200802417 A EA200802417 A EA 200802417A EA 200802417 A1 EA200802417 A1 EA 200802417A1
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EA
Eurasian Patent Office
Prior art keywords
antagonists
substituted phenylacetic
phenylacetic acids
methods
conditions
Prior art date
Application number
EA200802417A
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English (en)
Inventor
Томас Дадлер
Франсьен Фаруз
Керри Фаулер
Натали Хоторн
Данвен Хуанг
Цзинь Бохан
Мусон Ким
Эндрю Лавер
Джошуа Одинго
Эми Оливер
Марк Рид
Фуцян Руан
Юджин Торсет
Original Assignee
Икос Корпорейшн
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Икос Корпорейшн filed Critical Икос Корпорейшн
Publication of EA200802417A1 publication Critical patent/EA200802417A1/ru

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Abstract

Предложены замещенные производные фенилуксусной кислоты формулы (I), фармацевтические композиции, способы их получения и способы, которые являются полезными в лечении и предупреждении нарушений или состояний, чувствительных к модуляции DP-2-рецептора, в частности воспалительных и связанных с иммунитетом нарушений и состояний, таких как астма, аллергический ринит и атопический дерматит.
EA200802417A 2006-06-09 2007-06-08 Замещенные фенилуксусные кислоты как dp-2-антагонисты EA200802417A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81239906P 2006-06-09 2006-06-09
PCT/US2007/070805 WO2007146838A2 (en) 2006-06-09 2007-06-08 Substituted phenyl acetic acids as dp-2 antagonists

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EA200802417A1 true EA200802417A1 (ru) 2009-06-30

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EA200802417A EA200802417A1 (ru) 2006-06-09 2007-06-08 Замещенные фенилуксусные кислоты как dp-2-антагонисты
EA201200423A EA201200423A1 (ru) 2006-06-09 2007-06-08 Замещенные фенилуксусные кислоты как dp-2-антагонисты

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EP (1) EP2044017A2 (ru)
JP (1) JP2009539881A (ru)
CN (1) CN101490001A (ru)
AU (1) AU2007257841A1 (ru)
BR (1) BRPI0712332A2 (ru)
CA (1) CA2654927A1 (ru)
EA (2) EA200802417A1 (ru)
MX (1) MX2008015638A (ru)
NO (1) NO20090139L (ru)
WO (1) WO2007146838A2 (ru)

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KR101618068B1 (ko) 2007-10-19 2016-05-04 얀센 파마슈티카 엔.브이. γ-세크레타아제의 탄소 결합된 조절제
EP2212287B1 (en) * 2007-10-19 2012-02-01 Janssen Pharmaceutica, N.V. PIPERIDINYL AND PIPERAZINYL MODULATORS OF y-SECRETASE
SG177736A1 (en) * 2009-07-31 2012-02-28 Panmira Pharmaceuticals Llc Dermal formulations of dp2 receptor antagonists
CA2782085A1 (en) * 2010-01-06 2011-07-14 Panmira Pharmaceuticals, Llc Dp2 antagonist and uses thereof
WO2012004722A1 (en) 2010-07-05 2012-01-12 Actelion Pharmaceuticals Ltd 1-phenyl-substituted heterocyclyl derivatives and their use as prostaglandin d2 receptor modulators
EP2457900A1 (en) 2010-11-25 2012-05-30 Almirall, S.A. New pyrazole derivatives having CRTh2 antagonistic behaviour
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