NO20084418L - Azolopyridin-3-on derivater som inhibitorer av endoteliallipase - Google Patents

Azolopyridin-3-on derivater som inhibitorer av endoteliallipase

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Publication number
NO20084418L
NO20084418L NO20084418A NO20084418A NO20084418L NO 20084418 L NO20084418 L NO 20084418L NO 20084418 A NO20084418 A NO 20084418A NO 20084418 A NO20084418 A NO 20084418A NO 20084418 L NO20084418 L NO 20084418L
Authority
NO
Norway
Prior art keywords
inhibitors
derivatives
azolopyridin
endothelial lipase
lipase
Prior art date
Application number
NO20084418A
Other languages
English (en)
Inventor
Gerhard Zoller
Stefan Petry
Gunter Muller
Norbert Tennagels
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38190768&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20084418(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of NO20084418L publication Critical patent/NO20084418L/no

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
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    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems

Abstract

Foreliggende oppfinnelse angår azlopyridin-3-on derivater med generell formel (1) med betydningene indikert i beskrivelsen, dens farmasøytiske anvendelige salter og deres anvendelse som medisinske substanser. Forbindelsene er inhibitorer av endotel lipase.
NO20084418A 2006-03-28 2008-10-21 Azolopyridin-3-on derivater som inhibitorer av endoteliallipase NO20084418L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102006014688A DE102006014688A1 (de) 2006-03-28 2006-03-28 Azolopyridin-3-on-derivate als Inhibitoren von Lipasen und Phospholipasen
PCT/EP2007/002649 WO2007110216A1 (en) 2006-03-28 2007-03-26 Azolopyridin-3-one derivatives as inhibitors of endothelial lipase

Publications (1)

Publication Number Publication Date
NO20084418L true NO20084418L (no) 2008-12-23

Family

ID=38190768

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20084418A NO20084418L (no) 2006-03-28 2008-10-21 Azolopyridin-3-on derivater som inhibitorer av endoteliallipase

Country Status (17)

Country Link
US (1) US8148395B2 (no)
EP (1) EP2001879B1 (no)
JP (1) JP2009531357A (no)
KR (1) KR20080104032A (no)
CN (1) CN101415706A (no)
AR (1) AR060158A1 (no)
AU (1) AU2007229709A1 (no)
BR (1) BRPI0709217A2 (no)
CA (1) CA2647425A1 (no)
DE (1) DE102006014688A1 (no)
MA (1) MA30291B1 (no)
MX (1) MX2008012127A (no)
NO (1) NO20084418L (no)
RU (1) RU2008142535A (no)
TW (1) TW200813049A (no)
WO (1) WO2007110216A1 (no)
ZA (1) ZA200807135B (no)

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EP2310372B1 (en) 2008-07-09 2012-05-23 Sanofi Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
EP2351744B1 (en) 2008-10-17 2015-01-07 Shionogi & Co., Ltd. Acetic acid amide derivative having inhibitory activity on vascular endothelial lipase
WO2011074560A1 (ja) 2009-12-15 2011-06-23 塩野義製薬株式会社 血管内皮リパーゼ阻害活性を有するオキサジアゾール誘導体
WO2011107494A1 (de) 2010-03-03 2011-09-09 Sanofi Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2566853B1 (en) 2010-05-05 2017-01-25 Infinity Pharmaceuticals, Inc. Tetrazolones as inhibitors of fatty acid synthase
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EP2582709B1 (de) * 2010-06-18 2018-01-24 Sanofi Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
US20130197043A1 (en) 2010-08-31 2013-08-01 Snu R&Db Foundation Use of the fetal reprogramming of a ppar agonist
US8710050B2 (en) 2011-03-08 2014-04-29 Sanofi Di and tri- substituted oxathiazine derivatives, method for the production, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
EP2683704B1 (de) 2011-03-08 2014-12-17 Sanofi Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
EP2683705B1 (de) 2011-03-08 2015-04-22 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
WO2012120052A1 (de) 2011-03-08 2012-09-13 Sanofi Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
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US8952180B2 (en) 2011-09-27 2015-02-10 Bristol-Myers Squibb Company Pyrrolinone carboxamide compounds useful as endothelial lipase inhibitors
WO2013049096A1 (en) 2011-09-27 2013-04-04 Bristol-Myers Squibb Company Pyrrolinone carboxamide compounds useful as endothelial lipase inhibitors
EP2760840B1 (en) 2011-09-30 2015-08-12 Bristol-Myers Squibb Company Quinolinone carboxamide inhibitors of endothelial lipase
WO2013049104A1 (en) 2011-09-30 2013-04-04 Bristol-Myers Squibb Company Pyridinedione carboxamide inhibitors of endothelial lipase
EP2760834B1 (en) 2011-09-30 2016-11-16 Bristol-Myers Squibb Company Pyridinedione carboxamide inhibitors of endothelial lipase
PT2794618T (pt) * 2011-12-20 2017-01-17 Sanofi Sa Isotiazolopiridina-2-carboxamidas e seu uso como produtos farmacêuticos
US9394260B2 (en) 2012-04-03 2016-07-19 Bristol-Myers Squibb Company Pyrimidinone carboxamide inhibitors of endothelial lipase
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Also Published As

Publication number Publication date
BRPI0709217A2 (pt) 2011-07-12
DE102006014688A1 (de) 2007-10-04
TW200813049A (en) 2008-03-16
AR060158A1 (es) 2008-05-28
CA2647425A1 (en) 2007-10-04
RU2008142535A (ru) 2010-05-10
US8148395B2 (en) 2012-04-03
WO2007110216A1 (en) 2007-10-04
MA30291B1 (fr) 2009-03-02
CN101415706A (zh) 2009-04-22
EP2001879A1 (en) 2008-12-17
ZA200807135B (en) 2009-05-27
US20090054478A1 (en) 2009-02-26
MX2008012127A (es) 2008-10-03
AU2007229709A1 (en) 2007-10-04
KR20080104032A (ko) 2008-11-28
EP2001879B1 (en) 2013-08-21
JP2009531357A (ja) 2009-09-03

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