NO20090979L - (3-amino-1,2,3,4-tetrahydro-9H-karbazol-9-yl)-eddiksyrederivater - Google Patents
(3-amino-1,2,3,4-tetrahydro-9H-karbazol-9-yl)-eddiksyrederivaterInfo
- Publication number
- NO20090979L NO20090979L NO20090979A NO20090979A NO20090979L NO 20090979 L NO20090979 L NO 20090979L NO 20090979 A NO20090979 A NO 20090979A NO 20090979 A NO20090979 A NO 20090979A NO 20090979 L NO20090979 L NO 20090979L
- Authority
- NO
- Norway
- Prior art keywords
- carbazol
- tetrahydro
- amino
- acetic acid
- prostaglandin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Ophthalmology & Optometry (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Physical Education & Sports Medicine (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Foreliggende oppfinnelse vedrører (3-amino-1,2,3,4-tetrahydro-9H-karbazol-9-yl)-eddiksyrederivater med formel I hvori R1, R2, R3, R4, R5 og R6 er som beskrevet i beskrivelsen og deres anvendelse som prostaglandinreseptormodulatorer, nærmere bestemt som prostaglandin D2-reseptormodulatorer, i behandlingen av forskjellige prostaglandinmedierte sykdommer og lidelser, farmasøytiske sammensetninger som inneholder disse forbindelsene og fremgangsmåter for fremstilling av disse.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IB2006052723 | 2006-08-07 | ||
PCT/IB2007/053046 WO2008017989A1 (en) | 2006-08-07 | 2007-08-02 | (3-amino-1,2,3,4-tetrahydro-9h-carbazol-9-yl)-acetic acid derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20090979L true NO20090979L (no) | 2009-05-06 |
Family
ID=38805811
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20090979A NO20090979L (no) | 2006-08-07 | 2009-03-04 | (3-amino-1,2,3,4-tetrahydro-9H-karbazol-9-yl)-eddiksyrederivater |
Country Status (28)
Country | Link |
---|---|
US (1) | US8143304B2 (no) |
EP (2) | EP2316824A1 (no) |
JP (1) | JP5220013B2 (no) |
KR (1) | KR101411820B1 (no) |
CN (1) | CN101500996B (no) |
AR (1) | AR062222A1 (no) |
AT (1) | ATE530523T1 (no) |
AU (1) | AU2007282949B8 (no) |
BR (1) | BRPI0715179A2 (no) |
CA (1) | CA2658986C (no) |
CL (1) | CL2007002274A1 (no) |
CY (1) | CY1112276T1 (no) |
DK (1) | DK2051962T3 (no) |
ES (1) | ES2374321T3 (no) |
HK (1) | HK1130062A1 (no) |
HR (1) | HRP20120044T1 (no) |
IL (1) | IL196891A (no) |
MA (1) | MA30696B1 (no) |
MX (1) | MX2009001105A (no) |
MY (1) | MY147588A (no) |
NO (1) | NO20090979L (no) |
NZ (1) | NZ574705A (no) |
PL (1) | PL2051962T3 (no) |
PT (1) | PT2051962E (no) |
RU (1) | RU2448092C2 (no) |
SI (1) | SI2051962T1 (no) |
TW (1) | TWI408126B (no) |
WO (1) | WO2008017989A1 (no) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4051398B2 (ja) | 2004-03-11 | 2008-02-20 | アクテリオン ファマシューティカルズ リミテッド | テトラヒドロピリドインドール誘導体 |
EP1833791B1 (en) | 2004-12-27 | 2011-08-03 | Actelion Pharmaceuticals Ltd. | 2,3,4,9-tetrahydro-1h-carbazole derivatives as crth2 receptor antagonists |
MX2010008260A (es) | 2008-02-01 | 2010-12-20 | Amira Pharmaceuticals Inc | Antagonistas n,n-disustituidos de aminoalquilbifenilo de receptores d2 de prostaglandina. |
WO2009108720A2 (en) | 2008-02-25 | 2009-09-03 | Amira Pharmaceuticals, Inc. | Antagonists of prostaglandin d2 receptors |
JP2011526281A (ja) * | 2008-06-24 | 2011-10-06 | アミラ ファーマシューティカルズ,インク. | プロスタグランジンd2受容体のシクロアルカン[b]インドールアンタゴニスト |
GB2463788B (en) | 2008-09-29 | 2010-12-15 | Amira Pharmaceuticals Inc | Heteroaryl antagonists of prostaglandin D2 receptors |
US8524748B2 (en) | 2008-10-08 | 2013-09-03 | Panmira Pharmaceuticals, Llc | Heteroalkyl biphenyl antagonists of prostaglandin D2 receptors |
GB2465062B (en) | 2008-11-06 | 2011-04-13 | Amira Pharmaceuticals Inc | Cycloalkane(B)azaindole antagonists of prostaglandin D2 receptors |
MY152062A (en) | 2009-02-24 | 2014-08-15 | Merck Sharp & Dohme | Indole derivatives as crth2 receptor antagonists |
EP2461809A4 (en) | 2009-07-31 | 2013-06-19 | Panmira Pharmaceuticals Llc | OPHTHALMIC PHARMACEUTICAL COMPOSITIONS OF DP2 RECEPTOR ANTAGONSITES |
SG178252A1 (en) | 2009-08-05 | 2012-03-29 | Panmira Pharmaceuticals Llc | Dp2 antagonist and uses thereof |
ES2524079T3 (es) * | 2010-03-22 | 2014-12-04 | Actelion Pharmaceuticals Ltd. | Derivados de 3-(heteroaril-amino)-1,2,3,4-tetrahidro-9H-carbazol y su uso como moduladores del receptor de prostaglandina D2 |
EP2457900A1 (en) | 2010-11-25 | 2012-05-30 | Almirall, S.A. | New pyrazole derivatives having CRTh2 antagonistic behaviour |
AU2012241442B2 (en) | 2011-04-14 | 2017-01-12 | Idorsia Pharmaceuticals Ltd | 7-(heteroaryl-amino)-6,7,8,9-tetrahydropyrido(1,2-a)indol acetic acid derivatives and their use as prostaglandin D2 receptor modulators |
JP6152489B2 (ja) | 2014-03-17 | 2017-06-21 | アクテリオン ファーマシューティカルズ リミテッドActelion Pharmaceuticals Ltd | アザインドール酢酸誘導体及びプロスタグランジンd2受容体調節剤としてのそれらの使用 |
MX2016011900A (es) | 2014-03-18 | 2016-12-05 | Actelion Pharmaceuticals Ltd | Derivados de acido azaindol-acetico y su uso como moduladores del receptor de prostaglandina d2. |
CN104402798B (zh) * | 2014-10-21 | 2016-09-14 | 杭州瑞德化工有限公司 | 一种3-氨基-1,2,3,4-四氢咔唑的拆分方法 |
WO2016133793A1 (en) | 2015-02-16 | 2016-08-25 | Merck Sharp & Dohme Corp. | FACTOR IXa INHIBITORS |
KR20180053345A (ko) | 2015-09-15 | 2018-05-21 | 이도르시아 파마슈티컬스 리미티드 | 결정질 형태 |
CN112094223B (zh) * | 2019-06-18 | 2023-09-15 | 华东师范大学 | 一类脲基四氢咔唑类小分子有机化合物及用途 |
Family Cites Families (63)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4808608A (en) | 1986-01-23 | 1989-02-28 | Merck & Co., Inc. | Tetrahydrocarbazole 1-alkanoic acids, pharmaceutical compositions and use |
DE3631824A1 (de) | 1986-02-21 | 1988-03-31 | Bayer Ag | Cycloalkano(1.2-b)indol-sulfonamide |
US4988820A (en) * | 1986-02-21 | 1991-01-29 | Bayer Aktiengesellschaft | Cycloalkano(1,2-B) indole-sulponamides |
US5298626A (en) * | 1991-01-18 | 1994-03-29 | Hoechst-Roussel Pharmaceuticals Incorporated | Select cyclopent[b]indoles |
GB9113802D0 (en) * | 1991-06-26 | 1991-08-14 | Smithkline Beecham Plc | Medicaments |
US5350762A (en) * | 1993-03-08 | 1994-09-27 | Hoechst-Roussel Pharmaceuticals Incorporated | Tetrahydrocyclopent[B]indole methanamines and related compounds |
EP1184373A4 (en) * | 1999-04-20 | 2004-10-20 | Meiji Seika Kaisha | TRICYCLIC CONNECTIONS |
US20010047027A1 (en) | 2000-04-12 | 2001-11-29 | Marc Labelle | Prostaglandin D2 receptor antagonists |
CA2447779C (en) | 2001-05-23 | 2010-08-31 | Zhaoyin Wang | Dihydropyrrolo[1,2-a]indole and tetrahydropyrido[1,2-a]-indole derivatives as prostaglandin d2 receptor antagonists |
GB2408001B (en) | 2001-10-18 | 2006-03-29 | Derek Colin Tolley | Filtration of liquid media |
WO2003051837A2 (de) | 2001-12-14 | 2003-06-26 | Zentaris Gmbh | Tetrahydrocarbazolderivate als liganden für g-protein gekoppelte rezeptoren (gpcr) |
AR038136A1 (es) | 2002-01-24 | 2004-12-29 | Merck Frosst Canada Inc | Cicloalcanindoles con sustitucion con fluor composiciones que contienen estos compuestos y metodos de tratamiento |
SE0200356D0 (sv) | 2002-02-05 | 2002-02-05 | Astrazeneca Ab | Novel use |
SE0200411D0 (sv) | 2002-02-05 | 2002-02-05 | Astrazeneca Ab | Novel use |
AU2003231513A1 (en) * | 2002-05-16 | 2003-12-02 | Shionogi And Co., Ltd. | Pgd2 receptor antagonist |
AU2003231509A1 (en) * | 2002-05-16 | 2003-12-02 | Shionogi And Co., Ltd. | Compound exhibiting pgd 2 receptor antagonism |
GB2388540A (en) * | 2002-05-17 | 2003-11-19 | Bayer Ag | New use of Ramatroban |
TW200307542A (en) | 2002-05-30 | 2003-12-16 | Astrazeneca Ab | Novel compounds |
SE0201635D0 (sv) | 2002-05-30 | 2002-05-30 | Astrazeneca Ab | Novel compounds |
SE0202241D0 (sv) | 2002-07-17 | 2002-07-17 | Astrazeneca Ab | Novel Compounds |
DE60334015D1 (de) | 2002-10-30 | 2010-10-14 | Merck Frosst Canada Ltd | Pyridopyrrolizin- und pyridoindolizinderivate |
JPWO2004078719A1 (ja) | 2003-03-06 | 2006-06-08 | 小野薬品工業株式会社 | インドール誘導体化合物およびその化合物を有効成分とする薬剤 |
AU2004240705A1 (en) | 2003-05-20 | 2004-12-02 | Merck Frosst Canada & Co. | Fluoro-methanesulfonyl-substituted cycloalkanoindoles and their use as prostaglandin D2 antagonists |
SE0301569D0 (sv) | 2003-05-27 | 2003-05-27 | Astrazeneca Ab | Novel compounds |
WO2004111047A2 (en) | 2003-06-12 | 2004-12-23 | Merck Frosst Canada Ltd. | Cycloalkanepyrrolopyridines as dp receptor antagonists |
SE0302232D0 (sv) | 2003-08-18 | 2003-08-18 | Astrazeneca Ab | Novel Compounds |
WO2005033099A2 (en) | 2003-10-03 | 2005-04-14 | Glenmark Pharmaceuticals Ltd. | Novel dipeptidyl peptidase iv inhibitors; processes for their preparation and compositions thereof |
WO2005040112A1 (en) | 2003-10-14 | 2005-05-06 | Oxagen Limited | Compounds with pgd2 antagonist activity |
BRPI0415437A (pt) | 2003-10-14 | 2006-12-05 | Oxagen Ltd | composto, processo para a preparação e uso do mesmo, composição farmacêutica, processo para a preparação da mesma, e, produto |
GB0324763D0 (en) | 2003-10-23 | 2003-11-26 | Oxagen Ltd | Use of compounds in therapy |
GB2407318A (en) | 2003-10-23 | 2005-04-27 | Oxagen Ltd | Substituted Indol-3-yl acetic acid derivatives |
SE0303180D0 (sv) | 2003-11-26 | 2003-11-26 | Astrazeneca Ab | Novel compounds |
US7019022B2 (en) | 2003-12-15 | 2006-03-28 | Merck Frosst Canada & Co. | Substituted tetrahydrocarbazole and cyclopentanoindole derivatives |
WO2005073234A2 (en) | 2004-01-31 | 2005-08-11 | Actimis Pharmaceuticals, Inc. | Imidazo[1,2-c]pyrimidinylacetic acid derivatives |
AU2005229522A1 (en) * | 2004-03-11 | 2005-10-13 | Actelion Pharmaceuticals Ltd. | Indol-1-yl-acetic acid derivatives |
JP4051398B2 (ja) * | 2004-03-11 | 2008-02-20 | アクテリオン ファマシューティカルズ リミテッド | テトラヒドロピリドインドール誘導体 |
US20050234030A1 (en) | 2004-04-20 | 2005-10-20 | Wilmin Bartolini | Modulators of CRTH2, COX-2 and FAAH |
GB0412914D0 (en) | 2004-06-10 | 2004-07-14 | Oxagen Ltd | Compounds |
MY144903A (en) | 2004-06-17 | 2011-11-30 | Novartis Ag | Pyrrolopyridine derivatives and their use as crth2 antagonists |
CN101052397B (zh) | 2004-08-26 | 2011-07-06 | 埃科特莱茵药品有限公司 | 2-硫烷基-苯并咪唑-1-基-乙酸衍生物 |
MX2007003336A (es) * | 2004-09-21 | 2007-06-05 | Athersys Inc | Acidos aceticos de indol que muestran antagonismo de receptor crth2 y usos de los mismos. |
JP2008513511A (ja) | 2004-09-21 | 2008-05-01 | アサーシス, インク. | Crth2受容体拮抗作用を示すベンズイミダゾール酢酸およびこれらの使用 |
EP1833791B1 (en) * | 2004-12-27 | 2011-08-03 | Actelion Pharmaceuticals Ltd. | 2,3,4,9-tetrahydro-1h-carbazole derivatives as crth2 receptor antagonists |
DOP2006000016A (es) | 2005-01-26 | 2006-07-31 | Aventis Pharma Inc | 2-fenil-indoles como antagonistas del receptor de la prostaglandina d2. |
GB2422831A (en) | 2005-02-04 | 2006-08-09 | Oxagen Ltd | Pyrrolopyridines and their use in the treatment of diseases mediated by PGD2 at the CRTH2 receptor |
GB2422830A (en) | 2005-02-04 | 2006-08-09 | Oxagen Ltd | Pyrrolopyridines and their use in the treatment of diseases mediated by PGD2 at the CRTH2 receptor |
GB2422829A (en) | 2005-02-04 | 2006-08-09 | Oxagen Ltd | Pyrrolopyridines and their use in the treatment of diseases mediated by PGD2 at the CRTH2 receptor |
ES2395929T3 (es) | 2005-02-25 | 2013-02-18 | Ono Pharmaceutical Co., Ltd. | Compuestos de indol para tratar trastornos respiratorios |
GB0504150D0 (en) | 2005-03-01 | 2005-04-06 | Oxagen Ltd | Microcrystalline material |
GB0505048D0 (en) | 2005-03-11 | 2005-04-20 | Oxagen Ltd | Compounds with PGD antagonist activity |
WO2006125784A1 (en) | 2005-05-24 | 2006-11-30 | Laboratoires Serono S.A. | Tricyclic spiro derivatives as crth2 modulators |
GB0512944D0 (en) | 2005-06-24 | 2005-08-03 | Argenta Discovery Ltd | Indolizine compounds |
JP5064219B2 (ja) | 2005-07-22 | 2012-10-31 | 塩野義製薬株式会社 | Pgd2受容体アンタゴニスト活性を有するアザインドール酸誘導体 |
EP2397476A3 (en) | 2005-07-22 | 2011-12-28 | Shionogi & Co., Ltd. | Indole derivative having PGD2 receptor antagonist activity |
EP1915372B1 (en) | 2005-08-12 | 2013-11-20 | Merck Canada Inc. | Indole derivatives as crth2 receptor antagonists |
US20070203209A1 (en) | 2005-08-18 | 2007-08-30 | Wilmin Bartolini | Useful indole compounds |
US8143285B2 (en) | 2005-09-06 | 2012-03-27 | Shionogi & Co., Ltd. | Indolecarboxylic acid derivative having PGD2 receptor antagonistic activity |
GB0518783D0 (en) | 2005-09-14 | 2005-10-26 | Argenta Discovery Ltd | Indolizine compounds |
GB0521275D0 (en) | 2005-10-19 | 2005-11-30 | Argenta Discovery Ltd | 3-Aminoindole compounds |
GB0525141D0 (en) | 2005-12-09 | 2006-01-18 | Novartis Ag | Organic compounds |
GB0525143D0 (en) | 2005-12-09 | 2006-01-18 | Novartis Ag | Organic compounds |
GB0525144D0 (en) | 2005-12-09 | 2006-01-18 | Novartis Ag | Organic compounds |
GB0525337D0 (en) | 2005-12-13 | 2006-01-18 | Novartis Ag | Organic compounds |
-
2007
- 2007-08-02 PL PL07805287T patent/PL2051962T3/pl unknown
- 2007-08-02 AU AU2007282949A patent/AU2007282949B8/en not_active Ceased
- 2007-08-02 MY MYPI20090462A patent/MY147588A/en unknown
- 2007-08-02 US US12/376,932 patent/US8143304B2/en not_active Expired - Fee Related
- 2007-08-02 MX MX2009001105A patent/MX2009001105A/es active IP Right Grant
- 2007-08-02 EP EP11000641A patent/EP2316824A1/en not_active Withdrawn
- 2007-08-02 EP EP07805287A patent/EP2051962B1/en active Active
- 2007-08-02 SI SI200730818T patent/SI2051962T1/sl unknown
- 2007-08-02 BR BRPI0715179-9A patent/BRPI0715179A2/pt not_active IP Right Cessation
- 2007-08-02 WO PCT/IB2007/053046 patent/WO2008017989A1/en active Application Filing
- 2007-08-02 KR KR1020097004370A patent/KR101411820B1/ko active IP Right Grant
- 2007-08-02 CN CN2007800292169A patent/CN101500996B/zh not_active Expired - Fee Related
- 2007-08-02 DK DK07805287.5T patent/DK2051962T3/da active
- 2007-08-02 RU RU2009107889/04A patent/RU2448092C2/ru not_active IP Right Cessation
- 2007-08-02 PT PT07805287T patent/PT2051962E/pt unknown
- 2007-08-02 NZ NZ574705A patent/NZ574705A/en not_active IP Right Cessation
- 2007-08-02 ES ES07805287T patent/ES2374321T3/es active Active
- 2007-08-02 AT AT07805287T patent/ATE530523T1/de active
- 2007-08-02 CA CA2658986A patent/CA2658986C/en not_active Expired - Fee Related
- 2007-08-02 JP JP2009523396A patent/JP5220013B2/ja not_active Expired - Fee Related
- 2007-08-06 TW TW096128871A patent/TWI408126B/zh not_active IP Right Cessation
- 2007-08-06 CL CL200702274A patent/CL2007002274A1/es unknown
- 2007-08-06 AR ARP070103462A patent/AR062222A1/es unknown
-
2009
- 2009-02-04 IL IL196891A patent/IL196891A/en not_active IP Right Cessation
- 2009-02-17 MA MA31646A patent/MA30696B1/fr unknown
- 2009-03-04 NO NO20090979A patent/NO20090979L/no not_active Application Discontinuation
- 2009-10-28 HK HK09110028.6A patent/HK1130062A1/xx not_active IP Right Cessation
-
2012
- 2012-01-13 HR HR20120044T patent/HRP20120044T1/hr unknown
- 2012-01-25 CY CY20121100090T patent/CY1112276T1/el unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20090979L (no) | (3-amino-1,2,3,4-tetrahydro-9H-karbazol-9-yl)-eddiksyrederivater | |
NO20074592L (no) | Acetylenyl-pyrazolo-pyrimidinderivater som mGluR2-antagonister | |
NO20072371L (no) | Kinuklidinderivater og deres anvendelse som muskarine M3-reseptorantagonister | |
EA201170705A1 (ru) | Арилметилбензохиназолиноны в качестве позитивных аллостерических модуляторов рецептора м1 | |
MX2009006540A (es) | Derivados de ester y amida de indazolilo para el tratamiento de enfermedades mediadas por un receptor de glucocorticoides. | |
TW200612936A (en) | Indole derivatives | |
NO20084652L (no) | Deazapuriner anvendelige som inhibitorer av januskinaser | |
WO2008030412A3 (en) | Spiropiperidine beta-secretase inhibitors for the treatment of alzheimer's disease | |
MA32175B1 (fr) | Oxadiazoanthracènes pour le traitement du diabète | |
EA201171333A1 (ru) | Кристаллические сольваты и комплексы производных (1s)-1,5-ангидро-1-с-(3-((фенил)метил)фенил)-d-глюцитола с аминокислотами в качестве ингибиторов sglt2 для лечения диабета | |
NO20074258L (no) | Pyridin-2-karboksamidderivater som MGLUR5 antagonister | |
MX2007007103A (es) | Derivados espiro como inhibidores de lipoxigenasa. | |
ATE430744T1 (de) | Thiazolylpiperidin-derivate nützlich als h3 rezeptor modulatoren | |
NO20070224L (no) | 2-karbamid-4-fenyltiazolderivater, fremstilling og terapeutisk anvendelse derav | |
DE602008001725D1 (de) | 1-(1-benzylpiperidin-4-yl)benzimidazol-5-carbonsäurederivate zur behandlung von diabetes mellitus | |
NO20091626L (no) | MGLUR5-modulatorer | |
WO2008080844A9 (en) | Azaspiro derivatives | |
WO2008054698A3 (en) | Spiropiperidine beta-secretase inhibitors for the treatment of alzheimer's disease | |
EA200970065A1 (ru) | Производные пиперазинила, предназначенные для лечения заболеваний, опосредованных рецептором gpr38 | |
NO20083058L (no) | Cykloheksylsulfonamidderivater med H3 reseptor aktivitet | |
MY183111A (en) | 3-(heteroaryl-amino)-1,2,3,4-tetrahydro-9h-carbazole derivatives and their use as prostaglandin d2 receptor modulators | |
GEP20135806B (en) | Lactams as beta secretase inhibitors | |
DE602007001463D1 (de) | Pyrimidin-, chinazolin-, pteridin- und triazinderivate | |
NO20075477L (no) | Tetrahydro-pyridoazepin-8-one og beslektede forbindelser for behandling av schizofreni | |
DE602006014022D1 (de) | 5-substituierte indol-2-carbonsäureamidderivate |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |