US20040121313A1 - Methods for rapid detection and identification of bioagents in organs for transplantation - Google Patents

Methods for rapid detection and identification of bioagents in organs for transplantation Download PDF

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Publication number
US20040121313A1
US20040121313A1 US10/326,051 US32605102A US2004121313A1 US 20040121313 A1 US20040121313 A1 US 20040121313A1 US 32605102 A US32605102 A US 32605102A US 2004121313 A1 US2004121313 A1 US 2004121313A1
Authority
US
United States
Prior art keywords
nucleic acid
bioagent
base
mass
virus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US10/326,051
Other languages
English (en)
Inventor
David Ecker
Richard Griffey
Rangarajan Sampath
Steven Hofstadler
John McNeil
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ibis Biosciences Inc
Original Assignee
Isis Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isis Pharmaceuticals Inc filed Critical Isis Pharmaceuticals Inc
Priority to US10/325,526 priority Critical patent/US20040121311A1/en
Priority to US10/323,233 priority patent/US20040121309A1/en
Priority to US10/325,527 priority patent/US20040121335A1/en
Priority to US10/326,051 priority patent/US20040121313A1/en
Assigned to ISIS PHARMACEUTICALS, INC. reassignment ISIS PHARMACEUTICALS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: ECKER, DAVID J., GRIFFEY, RICHARD H., HOFSTADLER, STEVEN A., MCNEIL, JOHN, SAMPATH, RANGARAJAN
Priority to US10/660,122 priority patent/US7781162B2/en
Priority to US10/728,486 priority patent/US7718354B2/en
Priority to JP2005508560A priority patent/JP2006516193A/ja
Priority to CA002508726A priority patent/CA2508726A1/en
Priority to EP03814656A priority patent/EP1578399A4/en
Priority to PCT/US2003/038830 priority patent/WO2004052175A2/en
Priority to AU2003298030A priority patent/AU2003298030B2/en
Priority to AU2003297687A priority patent/AU2003297687B2/en
Priority to PCT/US2003/038761 priority patent/WO2004060278A2/en
Priority to JP2005508488A priority patent/JP2006508696A/ja
Priority to EP03796752A priority patent/EP1581657A4/en
Priority to CA002508584A priority patent/CA2508584A1/en
Publication of US20040121313A1 publication Critical patent/US20040121313A1/en
Assigned to IBIS BIOSCIENCES, INC. reassignment IBIS BIOSCIENCES, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: ISIS PHARMACEUTICALS, INC.
Priority to US11/869,449 priority patent/US20080311558A1/en
Priority to US11/930,002 priority patent/US8071309B2/en
Priority to US11/929,910 priority patent/US8214154B2/en
Priority to AU2010200686A priority patent/AU2010200686B2/en
Priority to US13/174,254 priority patent/US9416424B2/en
Priority to US13/243,960 priority patent/US8822156B2/en
Priority to US14/473,603 priority patent/US9725771B2/en
Priority to US15/237,261 priority patent/US20170044630A1/en
Abandoned legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
US10/326,051 2001-03-02 2002-12-18 Methods for rapid detection and identification of bioagents in organs for transplantation Abandoned US20040121313A1 (en)

Priority Applications (24)

Application Number Priority Date Filing Date Title
US10/325,526 US20040121311A1 (en) 2002-12-06 2002-12-18 Methods for rapid detection and identification of bioagents in livestock
US10/323,233 US20040121309A1 (en) 2002-12-06 2002-12-18 Methods for rapid detection and identification of bioagents in blood, bodily fluids, and bodily tissues
US10/325,527 US20040121335A1 (en) 2002-12-06 2002-12-18 Methods for rapid detection and identification of bioagents associated with host versus graft and graft versus host rejections
US10/326,051 US20040121313A1 (en) 2002-12-06 2002-12-18 Methods for rapid detection and identification of bioagents in organs for transplantation
US10/660,122 US7781162B2 (en) 2001-03-02 2003-09-11 Methods for rapid identification of pathogens in humans and animals
PCT/US2003/038761 WO2004060278A2 (en) 2002-12-06 2003-12-05 Methods for rapid identification of pathogens in humans and animals
JP2005508560A JP2006516193A (ja) 2002-12-06 2003-12-05 ヒトおよび動物における病原体の迅速な同定方法
CA002508584A CA2508584A1 (en) 2002-12-06 2003-12-05 Methods for rapid identification of pathogens in humans and animals
CA002508726A CA2508726A1 (en) 2002-12-06 2003-12-05 Methods for rapid identification of pathogens in humans and animals
EP03814656A EP1578399A4 (en) 2002-12-06 2003-12-05 METHODS FOR RAPID IDENTIFICATION OF PATHOGENS IN HUMANS AND BEETS
PCT/US2003/038830 WO2004052175A2 (en) 2002-12-06 2003-12-05 Methods for rapid identification of pathogens in humans and animals
AU2003298030A AU2003298030B2 (en) 2001-03-02 2003-12-05 Methods for rapid identification of pathogens in humans and animals
AU2003297687A AU2003297687B2 (en) 2001-03-02 2003-12-05 Methods for rapid identification of pathogens in humans and animals
US10/728,486 US7718354B2 (en) 2001-03-02 2003-12-05 Methods for rapid identification of pathogens in humans and animals
JP2005508488A JP2006508696A (ja) 2002-12-06 2003-12-05 ヒトおよび動物における病原体の迅速な同定方法
EP03796752A EP1581657A4 (en) 2002-12-06 2003-12-05 METHODS FOR THE RAPID IDENTIFICATION OF PATHOGENS IN HUMANS AND ANIMALS
US11/869,449 US20080311558A1 (en) 2001-03-02 2007-10-09 Methods For Rapid Identification Of Pathogens In Humans And Animals
US11/930,002 US8071309B2 (en) 2002-12-06 2007-10-30 Methods for rapid identification of pathogens in humans and animals
US11/929,910 US8214154B2 (en) 2001-03-02 2007-10-30 Systems for rapid identification of pathogens in humans and animals
AU2010200686A AU2010200686B2 (en) 2001-03-02 2010-02-25 Methods for rapid identification of pathogens in humans and animals
US13/174,254 US9416424B2 (en) 2001-03-02 2011-06-30 Methods for rapid identification of pathogens in humans and animals
US13/243,960 US8822156B2 (en) 2002-12-06 2011-09-23 Methods for rapid identification of pathogens in humans and animals
US14/473,603 US9725771B2 (en) 2002-12-06 2014-08-29 Methods for rapid identification of pathogens in humans and animals
US15/237,261 US20170044630A1 (en) 2001-03-02 2016-08-15 Methods For Rapid Identification Of Pathogens In Humans And Animals

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US43131902P 2002-12-06 2002-12-06
US10/326,051 US20040121313A1 (en) 2002-12-06 2002-12-18 Methods for rapid detection and identification of bioagents in organs for transplantation
US10/325,526 US20040121311A1 (en) 2002-12-06 2002-12-18 Methods for rapid detection and identification of bioagents in livestock
US10/325,527 US20040121335A1 (en) 2002-12-06 2002-12-18 Methods for rapid detection and identification of bioagents associated with host versus graft and graft versus host rejections
US10/323,233 US20040121309A1 (en) 2002-12-06 2002-12-18 Methods for rapid detection and identification of bioagents in blood, bodily fluids, and bodily tissues
US44344303P 2003-01-29 2003-01-29
US44378803P 2003-01-30 2003-01-30
US44752903P 2003-02-14 2003-02-14
US10/660,122 US7781162B2 (en) 2001-03-02 2003-09-11 Methods for rapid identification of pathogens in humans and animals

Related Parent Applications (2)

Application Number Title Priority Date Filing Date
US10/325,527 Continuation-In-Part US20040121335A1 (en) 2001-03-02 2002-12-18 Methods for rapid detection and identification of bioagents associated with host versus graft and graft versus host rejections
US10/325,526 Continuation-In-Part US20040121311A1 (en) 2001-03-02 2002-12-18 Methods for rapid detection and identification of bioagents in livestock

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US10/323,233 Continuation-In-Part US20040121309A1 (en) 2001-03-02 2002-12-18 Methods for rapid detection and identification of bioagents in blood, bodily fluids, and bodily tissues
US10/660,122 Continuation-In-Part US7781162B2 (en) 2001-03-02 2003-09-11 Methods for rapid identification of pathogens in humans and animals

Publications (1)

Publication Number Publication Date
US20040121313A1 true US20040121313A1 (en) 2004-06-24

Family

ID=32512832

Family Applications (7)

Application Number Title Priority Date Filing Date
US10/323,233 Abandoned US20040121309A1 (en) 2001-03-02 2002-12-18 Methods for rapid detection and identification of bioagents in blood, bodily fluids, and bodily tissues
US10/326,051 Abandoned US20040121313A1 (en) 2001-03-02 2002-12-18 Methods for rapid detection and identification of bioagents in organs for transplantation
US10/325,527 Abandoned US20040121335A1 (en) 2001-03-02 2002-12-18 Methods for rapid detection and identification of bioagents associated with host versus graft and graft versus host rejections
US10/325,526 Abandoned US20040121311A1 (en) 2001-03-02 2002-12-18 Methods for rapid detection and identification of bioagents in livestock
US10/660,122 Expired - Fee Related US7781162B2 (en) 2001-03-02 2003-09-11 Methods for rapid identification of pathogens in humans and animals
US11/869,449 Abandoned US20080311558A1 (en) 2001-03-02 2007-10-09 Methods For Rapid Identification Of Pathogens In Humans And Animals
US11/929,910 Expired - Fee Related US8214154B2 (en) 2001-03-02 2007-10-30 Systems for rapid identification of pathogens in humans and animals

Family Applications Before (1)

Application Number Title Priority Date Filing Date
US10/323,233 Abandoned US20040121309A1 (en) 2001-03-02 2002-12-18 Methods for rapid detection and identification of bioagents in blood, bodily fluids, and bodily tissues

Family Applications After (5)

Application Number Title Priority Date Filing Date
US10/325,527 Abandoned US20040121335A1 (en) 2001-03-02 2002-12-18 Methods for rapid detection and identification of bioagents associated with host versus graft and graft versus host rejections
US10/325,526 Abandoned US20040121311A1 (en) 2001-03-02 2002-12-18 Methods for rapid detection and identification of bioagents in livestock
US10/660,122 Expired - Fee Related US7781162B2 (en) 2001-03-02 2003-09-11 Methods for rapid identification of pathogens in humans and animals
US11/869,449 Abandoned US20080311558A1 (en) 2001-03-02 2007-10-09 Methods For Rapid Identification Of Pathogens In Humans And Animals
US11/929,910 Expired - Fee Related US8214154B2 (en) 2001-03-02 2007-10-30 Systems for rapid identification of pathogens in humans and animals

Country Status (5)

Country Link
US (7) US20040121309A1 (US20040121313A1-20040624-P00820.png)
EP (1) EP1581657A4 (US20040121313A1-20040624-P00820.png)
JP (1) JP2006508696A (US20040121313A1-20040624-P00820.png)
CA (1) CA2508584A1 (US20040121313A1-20040624-P00820.png)
WO (1) WO2004052175A2 (US20040121313A1-20040624-P00820.png)

Cited By (46)

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US20040219517A1 (en) * 2001-03-02 2004-11-04 Ecker David J. Methods for rapid identification of pathogens in humans and animals
US20050270191A1 (en) * 2004-05-24 2005-12-08 Isis Pharmaceuticals, Inc. Mass spectrometry with selective ion filtration by digital thresholding
US20080227087A1 (en) * 2005-10-11 2008-09-18 Ann Huletsky Sequences for detection and identification of methicillin-resistant Staphylococcus aureus (MRSA) of MREJ types xi to xx
US20090263809A1 (en) * 2008-03-20 2009-10-22 Zygem Corporation Limited Methods for Identification of Bioagents
US7666592B2 (en) 2004-02-18 2010-02-23 Ibis Biosciences, Inc. Methods for concurrent identification and quantification of an unknown bioagent
US7666588B2 (en) 2001-03-02 2010-02-23 Ibis Biosciences, Inc. Methods for rapid forensic analysis of mitochondrial DNA and characterization of mitochondrial DNA heteroplasmy
US7718354B2 (en) 2001-03-02 2010-05-18 Ibis Biosciences, Inc. Methods for rapid identification of pathogens in humans and animals
US7741036B2 (en) 2001-03-02 2010-06-22 Ibis Biosciences, Inc. Method for rapid detection and identification of bioagents
US7811753B2 (en) 2004-07-14 2010-10-12 Ibis Biosciences, Inc. Methods for repairing degraded DNA
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US7956175B2 (en) 2003-09-11 2011-06-07 Ibis Biosciences, Inc. Compositions for use in identification of bacteria
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US8057993B2 (en) 2003-04-26 2011-11-15 Ibis Biosciences, Inc. Methods for identification of coronaviruses
US8071309B2 (en) 2002-12-06 2011-12-06 Ibis Biosciences, Inc. Methods for rapid identification of pathogens in humans and animals
US8084207B2 (en) 2005-03-03 2011-12-27 Ibis Bioscience, Inc. Compositions for use in identification of papillomavirus
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