UA73076C2 - Aqueous aerosol preparations containing biologically active macromolecules and method for their manufacture - Google Patents
Aqueous aerosol preparations containing biologically active macromolecules and method for their manufacture Download PDFInfo
- Publication number
- UA73076C2 UA73076C2 UA2000031252A UA2000031252A UA73076C2 UA 73076 C2 UA73076 C2 UA 73076C2 UA 2000031252 A UA2000031252 A UA 2000031252A UA 2000031252 A UA2000031252 A UA 2000031252A UA 73076 C2 UA73076 C2 UA 73076C2
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- UA
- Ukraine
- Prior art keywords
- aqueous aerosol
- preparation according
- aerosol preparation
- active substance
- insulin
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- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/44—Oxidoreductases (1)
- A61K38/446—Superoxide dismutase (1.15)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Zoology (AREA)
- Dispersion Chemistry (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19733651A DE19733651A1 (de) | 1997-08-04 | 1997-08-04 | Wässrige Aerosolzubereitungen enthaltend biologisch aktive Markomoleküle und Verfahren zur Erzeugung entsprechender Aerosole |
| PCT/EP1998/004803 WO1999007340A1 (de) | 1997-08-04 | 1998-07-31 | Wässrige aerosolzubereitungen enthaltend biologisch aktive makromoleküle und verfahren zur erzeugung entsprechender aerosole |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA73076C2 true UA73076C2 (en) | 2005-06-15 |
Family
ID=7837935
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA2000031252A UA73076C2 (en) | 1997-08-04 | 1998-07-31 | Aqueous aerosol preparations containing biologically active macromolecules and method for their manufacture |
Country Status (36)
| Country | Link |
|---|---|
| US (1) | US20030064032A1 (bg) |
| EP (2) | EP1003478B1 (bg) |
| JP (1) | JP2001513492A (bg) |
| KR (1) | KR20010022636A (bg) |
| CN (1) | CN1177581C (bg) |
| AR (1) | AR016581A1 (bg) |
| AT (1) | ATE301987T1 (bg) |
| AU (1) | AU753673B2 (bg) |
| BG (1) | BG64966B1 (bg) |
| BR (1) | BR9811827A (bg) |
| CA (1) | CA2297174A1 (bg) |
| CO (1) | CO4960637A1 (bg) |
| DE (2) | DE19733651A1 (bg) |
| DK (1) | DK1003478T3 (bg) |
| EA (1) | EA002255B1 (bg) |
| EE (1) | EE05053B1 (bg) |
| ES (1) | ES2248915T3 (bg) |
| HK (1) | HK1027749A1 (bg) |
| HR (1) | HRP980425B1 (bg) |
| HU (1) | HUP0003805A3 (bg) |
| ID (1) | ID24200A (bg) |
| IL (2) | IL134115A0 (bg) |
| MY (1) | MY132852A (bg) |
| NO (1) | NO20000553L (bg) |
| NZ (1) | NZ503160A (bg) |
| PL (1) | PL338421A1 (bg) |
| PT (1) | PT1003478E (bg) |
| RS (1) | RS49705B (bg) |
| SI (1) | SI1003478T1 (bg) |
| SK (1) | SK285637B6 (bg) |
| TR (1) | TR200000312T2 (bg) |
| TW (1) | TWI222887B (bg) |
| UA (1) | UA73076C2 (bg) |
| UY (1) | UY25122A1 (bg) |
| WO (1) | WO1999007340A1 (bg) |
| ZA (1) | ZA986931B (bg) |
Families Citing this family (71)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030215396A1 (en) | 1999-09-15 | 2003-11-20 | Boehringer Ingelheim Pharma Kg | Method for the production of propellant gas-free aerosols from aqueous medicament preparations |
| US7963955B2 (en) | 1998-02-27 | 2011-06-21 | Boehringer Ingelheim International Gmbh | Container for a medicinal liquid |
| SE9801495D0 (sv) * | 1998-04-28 | 1998-04-28 | Astra Ab | Protein formulationa |
| US20060171899A1 (en) * | 1998-12-10 | 2006-08-03 | Akwete Adjei | Water-stabilized aerosol formulation system and method of making |
| RU2140285C1 (ru) * | 1999-01-25 | 1999-10-27 | Гапонюк Петр Яковлевич | Противовирусное средство - капли в нос "гриппферон" |
| US6350432B1 (en) * | 1999-03-19 | 2002-02-26 | Generex Pharmaceuticals Incorporated | Pressurized container having an aerosolized pharmaceutical composition |
| NZ519403A (en) * | 2001-06-21 | 2005-03-24 | Pfizer Prod Inc | Use of insulin in a medicament to reduce weight gain in a diabetic patient who is using exogenous insulin to control blood sugar levels |
| DE102004001451A1 (de) | 2004-01-08 | 2005-08-11 | Boehringer Ingelheim International Gmbh | Vorrichtung zum Haltern eines fluidischen Bauteiles |
| DE102004011381A1 (de) | 2004-03-05 | 2005-09-15 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Impaktionsdüse für treibgasbetriebene Dosieraerosole |
| US7611709B2 (en) | 2004-05-10 | 2009-11-03 | Boehringer Ingelheim Pharma Gmbh And Co. Kg | 1,4 O-linked saccharose derivatives for stabilization of antibodies or antibody derivatives |
| US7723306B2 (en) | 2004-05-10 | 2010-05-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Spray-dried powder comprising at least one 1,4 O-linked saccharose-derivative and methods for their preparation |
| US7727962B2 (en) | 2004-05-10 | 2010-06-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Powder comprising new compositions of oligosaccharides and methods for their preparation |
| DE102005024439A1 (de) | 2005-05-24 | 2006-12-07 | Boehringer Ingelheim International Gmbh | Zerstäuber |
| DE102005029746B4 (de) | 2005-06-24 | 2017-10-26 | Boehringer Ingelheim International Gmbh | Zerstäuber |
| CN101247845B (zh) * | 2005-06-27 | 2013-04-24 | 世界卫生组织 | 疫苗喷雾器 |
| CN101247897B (zh) | 2005-08-24 | 2013-06-12 | 贝林格尔·英格海姆国际有限公司 | 雾化器 |
| DE102006009637A1 (de) | 2005-10-28 | 2007-05-03 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Inhalator mit Mundstück mit mikrobiologischer Schutzfunktion |
| EP1954242A4 (en) * | 2005-11-30 | 2012-08-01 | Generex Pharm Inc | ORALLY ABSORPTED PHARMACEUTICAL FORMULATION AND METHOD OF ADMINISTRATION |
| EP1792660A1 (en) | 2005-12-02 | 2007-06-06 | Boehringer Ingelheim Pharma GmbH & Co. KG | Dispensing device |
| DE102006014433A1 (de) | 2006-03-27 | 2007-10-04 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Dosieraerosole für die Verabreichung von pharmazeutischen Zubereitungen |
| DE102006016903A1 (de) | 2006-04-11 | 2007-10-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Inhalator |
| DE102006016901A1 (de) | 2006-04-11 | 2007-10-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Mundstück für einen Inhalator |
| US7841338B2 (en) | 2006-04-13 | 2010-11-30 | Boehringer Ingelheim International Gmbh | Dispensing device |
| EP1844807A1 (de) | 2006-04-13 | 2007-10-17 | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG | Medikamentenmagazin, sowie Vorrichtung und Verfahren zum Öffnen desselben; Mehrdosispulverinhalator |
| EP1844809A1 (de) | 2006-04-13 | 2007-10-17 | Boehringer Ingelheim Pharma GmbH & Co. KG | Medikamentenmagazin für einen Inhalator, sowie Mehrdosispulverinhalator |
| EP1844808A1 (de) | 2006-04-13 | 2007-10-17 | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG | Medikamenten-Ausgabevorrichtung |
| DE102006022002A1 (de) | 2006-05-10 | 2007-11-15 | Boehringer Ingelheim International Gmbh | Zerstäuber und Verfahren zur Zerstäubung von Fluid |
| DE102006043637A1 (de) | 2006-05-18 | 2007-11-22 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Zerstäuber |
| US8061350B2 (en) | 2006-06-02 | 2011-11-22 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Process and device for dosing pharmaceutical agents |
| DE102007020578A1 (de) | 2007-05-02 | 2008-11-06 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Wässrige Aerosolzubereitungen enthaltend therapeutisch wirksame Mikroorganismen oder Teile von Mikroorganismen und Verfahren zur Erzeugung entsprechender Aerosole |
| DE102007023012A1 (de) | 2007-05-15 | 2008-11-20 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Zerstäuber und Filter |
| EP2155306A2 (en) | 2007-06-15 | 2010-02-24 | Boehringer Ingelheim International GmbH | Inhaler |
| EP2011536A1 (en) | 2007-07-06 | 2009-01-07 | Boehringer Ingelheim Pharma GmbH & Co. KG | Inhaler |
| CN100593424C (zh) * | 2007-07-18 | 2010-03-10 | 北京万生药业有限责任公司 | 一种氧气湿化及输送装置 |
| DE102007033861A1 (de) | 2007-07-20 | 2009-07-02 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pulverinhalator |
| DE102007033860A1 (de) | 2007-07-20 | 2009-01-22 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Prüfvorrichtung |
| DE102007036411A1 (de) | 2007-07-20 | 2009-02-12 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pulverinhalator |
| DE102007036413A1 (de) | 2007-08-02 | 2009-02-05 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Vorrichtung und Verfahren zur Bestimmung des Feuchtegehalts eines Verpackungsmaterials |
| DE102007034156A1 (de) | 2007-07-21 | 2009-01-22 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Vorrichtung und Verfahren zur Bestimmung des Feuchtegehalts eines Verpackungsmaterials |
| DE102007052871A1 (de) | 2007-11-02 | 2009-05-07 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Kapsel zur Aufnahme von pharmazeutischen Wirkstoffformulierungen |
| DE102007058112A1 (de) | 2007-12-03 | 2009-06-04 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pulverinhalator mit Wirkstofftablette |
| EP2077132A1 (en) | 2008-01-02 | 2009-07-08 | Boehringer Ingelheim Pharma GmbH & Co. KG | Dispensing device, storage device and method for dispensing a formulation |
| MX2010009838A (es) | 2008-03-17 | 2010-09-28 | Boehringer Ingelheim Int | Deposito y pulverizador. |
| EP2135632A1 (de) | 2008-06-20 | 2009-12-23 | Boehringer Ingelheim International Gmbh | Inhalator |
| EP2198972A1 (de) | 2008-12-18 | 2010-06-23 | Boehringer Ingelheim International GmbH | Reservoir und Zerstäuber |
| WO2010076012A1 (de) | 2009-01-02 | 2010-07-08 | Boehringer Ingelheim International Gmbh | Bauteil und inhalator sowie verfahren zur herstellung eines bauteils |
| EP2408500B1 (en) | 2009-03-17 | 2015-04-29 | Boehringer Ingelheim International GmbH | Dispensing device, and storage device for dispensing a formulation |
| US8905017B2 (en) | 2009-03-17 | 2014-12-09 | Boehringer Ingelheim International Gmbh | Reservoir and atomizer |
| US10011906B2 (en) | 2009-03-31 | 2018-07-03 | Beohringer Ingelheim International Gmbh | Method for coating a surface of a component |
| US9108011B2 (en) | 2009-04-28 | 2015-08-18 | Boehringer Ingelheim International Gmbh | Inhalation device |
| EP3508239B1 (de) | 2009-05-18 | 2020-12-23 | Boehringer Ingelheim International GmbH | Adapter, inhalationseinrichtung und zerstäuber |
| US9084660B2 (en) | 2009-06-25 | 2015-07-21 | Boehringer Ingelheim Vetmedica Gmbh | Inhaler |
| US8746244B2 (en) | 2009-10-02 | 2014-06-10 | Boehringer Ingelheim International Gmbh | Powder inhaler |
| US10016568B2 (en) | 2009-11-25 | 2018-07-10 | Boehringer Ingelheim International Gmbh | Nebulizer |
| WO2011064163A1 (en) | 2009-11-25 | 2011-06-03 | Boehringer Ingelheim International Gmbh | Nebulizer |
| UA107097C2 (en) | 2009-11-25 | 2014-11-25 | Бьорінгер Інгельхайм Інтернаціональ Гмбх | Dispenser |
| JP5874724B2 (ja) | 2010-06-24 | 2016-03-02 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ネブライザ |
| EP2694220B1 (de) | 2011-04-01 | 2020-05-06 | Boehringer Ingelheim International GmbH | Medizinisches gerät mit behälter |
| US9827384B2 (en) | 2011-05-23 | 2017-11-28 | Boehringer Ingelheim International Gmbh | Nebulizer |
| WO2013152894A1 (de) | 2012-04-13 | 2013-10-17 | Boehringer Ingelheim International Gmbh | Zerstäuber mit kodiermitteln |
| CN103386125A (zh) * | 2012-05-08 | 2013-11-13 | 刘江秋 | 肾综合征出血热鼻黏膜免疫气溶胶疫苗的研制 |
| ES2836977T3 (es) | 2013-08-09 | 2021-06-28 | Boehringer Ingelheim Int | Nebulizador |
| EP3030298B1 (en) | 2013-08-09 | 2017-10-11 | Boehringer Ingelheim International GmbH | Nebulizer |
| CN103575718A (zh) * | 2013-11-21 | 2014-02-12 | 中国人民解放军63975部队 | 用量子点荧光传感体系测定蛋白喷剂雾化效果的方法 |
| ES2874029T3 (es) | 2014-05-07 | 2021-11-04 | Boehringer Ingelheim Int | Nebulizador |
| ES2954961T3 (es) | 2014-05-07 | 2023-11-27 | Boehringer Ingelheim Int | Unidad, nebulizador y método |
| UA121114C2 (uk) | 2014-05-07 | 2020-04-10 | Бьорінгер Інгельхайм Інтернаціональ Гмбх | Небулайзер, індикаторний пристрій і контейнер |
| CN104474534A (zh) * | 2014-12-22 | 2015-04-01 | 哈德逊（天津）生物技术有限责任公司 | 白介素-18抗病毒口腔喷剂 |
| EP3563894B1 (en) * | 2018-05-04 | 2021-12-22 | Boehringer Ingelheim International GmbH | Nebulizer and container |
| EP4196091A4 (en) * | 2020-08-14 | 2024-02-07 | Univ Istanbul Rektoerluegue | USE OF A HEPARIN COMPOSITION FOR THE TREATMENT OF VIRAL LUNG DISEASES, ACUTE AND/OR CHRONIC LUNG DISEASES |
| CN114712336B (zh) * | 2020-12-22 | 2023-11-07 | 黄嘉若 | 一种用于肺部给药的水性气溶胶、制备方法和用途 |
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| US4153689A (en) * | 1975-06-13 | 1979-05-08 | Takeda Chemical Industries, Ltd. | Stable insulin preparation for nasal administration |
| AU558474B2 (en) * | 1981-07-17 | 1987-01-29 | Nordisk Insulinlaboratorium | A stable aqueous, therapeutic insulin preparation and a process for preparing it |
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| DE3827121A1 (de) * | 1988-08-10 | 1990-02-15 | Hoechst Ag | Verfahren zur herstellung von des-b30-insulinen und des-b30-insulinderivaten |
| CA2050905A1 (en) * | 1989-02-23 | 1990-08-24 | George R. Felt | Therapeutic aerosol formulations |
| JP2704546B2 (ja) * | 1989-04-04 | 1998-01-26 | 光利 太良 | Ａｔｌｌ治療用吸入剤 |
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| IL99699A (en) * | 1990-10-10 | 2002-04-21 | Autoimmune Inc | Drug with the option of oral, intra-intestinal, or inhaled dosing for suppression of autoimmune response associated with type I diabetes |
| CA2082951C (en) * | 1991-03-15 | 1999-12-21 | Robert M. Platz | Pulmonary administration of granulocyte colony stimulating factor |
| DE4117078A1 (de) * | 1991-05-25 | 1992-11-26 | Boehringer Ingelheim Kg | Verfahren zur herstellung therapeutisch anwendbarer aerosole |
| US5888477A (en) * | 1993-01-29 | 1999-03-30 | Aradigm Corporation | Use of monomeric insulin as a means for improving the bioavailability of inhaled insulin |
| US5354934A (en) * | 1993-02-04 | 1994-10-11 | Amgen Inc. | Pulmonary administration of erythropoietin |
| DE69431290D1 (de) * | 1993-02-12 | 2002-10-10 | Avant Immunotherapeutics Inc | PULMONÄRE VERABREICHUNG DES LÖSLICHEN KOMPLEMENT-RECEPTORS TYP 1 sCR1 |
| IL109120A0 (en) * | 1993-03-24 | 1994-06-24 | Boehringer Ingelheim Pharma | Inhibition of pulmonary oxygen toxicity using manganese superoxide dismutase |
| WO1995003034A1 (en) * | 1993-07-19 | 1995-02-02 | Amgen Inc. | Stabilization of aerosolized proteins |
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-
1997
- 1997-08-04 DE DE19733651A patent/DE19733651A1/de not_active Ceased
-
1998
- 1998-07-31 SI SI9830799T patent/SI1003478T1/sl unknown
- 1998-07-31 AT AT98943814T patent/ATE301987T1/de active
- 1998-07-31 SK SK150-2000A patent/SK285637B6/sk not_active IP Right Cessation
- 1998-07-31 UA UA2000031252A patent/UA73076C2/uk unknown
- 1998-07-31 AU AU91577/98A patent/AU753673B2/en not_active Ceased
- 1998-07-31 DK DK98943814T patent/DK1003478T3/da active
- 1998-07-31 EA EA200000190A patent/EA002255B1/ru not_active IP Right Cessation
- 1998-07-31 WO PCT/EP1998/004803 patent/WO1999007340A1/de not_active Application Discontinuation
- 1998-07-31 EP EP98943814A patent/EP1003478B1/de not_active Expired - Lifetime
- 1998-07-31 EP EP05002747A patent/EP1527771A3/de not_active Withdrawn
- 1998-07-31 IL IL13411598A patent/IL134115A0/xx active IP Right Grant
- 1998-07-31 RS YUP-56/00A patent/RS49705B/sr unknown
- 1998-07-31 PT PT98943814T patent/PT1003478E/pt unknown
- 1998-07-31 ES ES98943814T patent/ES2248915T3/es not_active Expired - Lifetime
- 1998-07-31 JP JP2000506934A patent/JP2001513492A/ja active Pending
- 1998-07-31 ID IDW20000210A patent/ID24200A/id unknown
- 1998-07-31 NZ NZ503160A patent/NZ503160A/en unknown
- 1998-07-31 CN CNB988078953A patent/CN1177581C/zh not_active Expired - Fee Related
- 1998-07-31 TR TR2000/00312T patent/TR200000312T2/xx unknown
- 1998-07-31 DE DE59813014T patent/DE59813014D1/de not_active Expired - Lifetime
- 1998-07-31 PL PL98338421A patent/PL338421A1/xx not_active Application Discontinuation
- 1998-07-31 CA CA002297174A patent/CA2297174A1/en not_active Abandoned
- 1998-07-31 EE EEP200000065A patent/EE05053B1/xx not_active IP Right Cessation
- 1998-07-31 BR BR9811827-7A patent/BR9811827A/pt not_active Application Discontinuation
- 1998-07-31 KR KR1020007001230A patent/KR20010022636A/ko not_active Application Discontinuation
- 1998-07-31 HU HU0003805A patent/HUP0003805A3/hu unknown
- 1998-08-03 ZA ZA9806931A patent/ZA986931B/xx unknown
- 1998-08-03 CO CO98044242A patent/CO4960637A1/es unknown
- 1998-08-03 HR HR980425A patent/HRP980425B1/xx not_active IP Right Cessation
- 1998-08-03 UY UY25122A patent/UY25122A1/es not_active IP Right Cessation
- 1998-08-03 MY MYPI98003548A patent/MY132852A/en unknown
- 1998-08-03 AR ARP980103825A patent/AR016581A1/es not_active Suspension/Interruption
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1999
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2000
- 2000-01-18 IL IL134115A patent/IL134115A/en not_active IP Right Cessation
- 2000-02-03 NO NO20000553A patent/NO20000553L/no not_active Application Discontinuation
- 2000-02-04 BG BG104130A patent/BG64966B1/bg active Active
- 2000-10-26 HK HK00106819A patent/HK1027749A1/xx not_active IP Right Cessation
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2002
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