DK1003478T3 - Vandige aerosolpræparater indeholdende biologisk aktive makromolekyler og fremgangsmåde til fremstilling af tilsvarende aerosoler - Google Patents
Vandige aerosolpræparater indeholdende biologisk aktive makromolekyler og fremgangsmåde til fremstilling af tilsvarende aerosolerInfo
- Publication number
- DK1003478T3 DK1003478T3 DK98943814T DK98943814T DK1003478T3 DK 1003478 T3 DK1003478 T3 DK 1003478T3 DK 98943814 T DK98943814 T DK 98943814T DK 98943814 T DK98943814 T DK 98943814T DK 1003478 T3 DK1003478 T3 DK 1003478T3
- Authority
- DK
- Denmark
- Prior art keywords
- biologically active
- preparations containing
- aerosol preparations
- aqueous aerosol
- containing biologically
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/44—Oxidoreductases (1)
- A61K38/446—Superoxide dismutase (1.15)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Diabetes (AREA)
- Zoology (AREA)
- Dispersion Chemistry (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19733651A DE19733651A1 (de) | 1997-08-04 | 1997-08-04 | Wässrige Aerosolzubereitungen enthaltend biologisch aktive Markomoleküle und Verfahren zur Erzeugung entsprechender Aerosole |
| PCT/EP1998/004803 WO1999007340A1 (de) | 1997-08-04 | 1998-07-31 | Wässrige aerosolzubereitungen enthaltend biologisch aktive makromoleküle und verfahren zur erzeugung entsprechender aerosole |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1003478T3 true DK1003478T3 (da) | 2005-10-24 |
Family
ID=7837935
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98943814T DK1003478T3 (da) | 1997-08-04 | 1998-07-31 | Vandige aerosolpræparater indeholdende biologisk aktive makromolekyler og fremgangsmåde til fremstilling af tilsvarende aerosoler |
Country Status (36)
| Country | Link |
|---|---|
| US (1) | US20030064032A1 (da) |
| EP (2) | EP1003478B1 (da) |
| JP (1) | JP2001513492A (da) |
| KR (1) | KR20010022636A (da) |
| CN (1) | CN1177581C (da) |
| AR (1) | AR016581A1 (da) |
| AT (1) | ATE301987T1 (da) |
| AU (1) | AU753673B2 (da) |
| BG (1) | BG64966B1 (da) |
| BR (1) | BR9811827A (da) |
| CA (1) | CA2297174A1 (da) |
| CO (1) | CO4960637A1 (da) |
| DE (2) | DE19733651A1 (da) |
| DK (1) | DK1003478T3 (da) |
| EA (1) | EA002255B1 (da) |
| EE (1) | EE05053B1 (da) |
| ES (1) | ES2248915T3 (da) |
| HK (1) | HK1027749A1 (da) |
| HR (1) | HRP980425B1 (da) |
| HU (1) | HUP0003805A3 (da) |
| ID (1) | ID24200A (da) |
| IL (2) | IL134115A0 (da) |
| MY (1) | MY132852A (da) |
| NO (1) | NO20000553L (da) |
| NZ (1) | NZ503160A (da) |
| PL (1) | PL338421A1 (da) |
| PT (1) | PT1003478E (da) |
| RS (1) | RS49705B (da) |
| SI (1) | SI1003478T1 (da) |
| SK (1) | SK285637B6 (da) |
| TR (1) | TR200000312T2 (da) |
| TW (1) | TWI222887B (da) |
| UA (1) | UA73076C2 (da) |
| UY (1) | UY25122A1 (da) |
| WO (1) | WO1999007340A1 (da) |
| ZA (1) | ZA986931B (da) |
Families Citing this family (71)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030215396A1 (en) | 1999-09-15 | 2003-11-20 | Boehringer Ingelheim Pharma Kg | Method for the production of propellant gas-free aerosols from aqueous medicament preparations |
| US7963955B2 (en) | 1998-02-27 | 2011-06-21 | Boehringer Ingelheim International Gmbh | Container for a medicinal liquid |
| SE9801495D0 (sv) * | 1998-04-28 | 1998-04-28 | Astra Ab | Protein formulationa |
| US20060171899A1 (en) * | 1998-12-10 | 2006-08-03 | Akwete Adjei | Water-stabilized aerosol formulation system and method of making |
| RU2140285C1 (ru) * | 1999-01-25 | 1999-10-27 | Гапонюк Петр Яковлевич | Противовирусное средство - капли в нос "гриппферон" |
| US6350432B1 (en) * | 1999-03-19 | 2002-02-26 | Generex Pharmaceuticals Incorporated | Pressurized container having an aerosolized pharmaceutical composition |
| NZ519403A (en) * | 2001-06-21 | 2005-03-24 | Pfizer Prod Inc | Use of insulin in a medicament to reduce weight gain in a diabetic patient who is using exogenous insulin to control blood sugar levels |
| DE102004001451A1 (de) * | 2004-01-08 | 2005-08-11 | Boehringer Ingelheim International Gmbh | Vorrichtung zum Haltern eines fluidischen Bauteiles |
| DE102004011381A1 (de) | 2004-03-05 | 2005-09-15 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Impaktionsdüse für treibgasbetriebene Dosieraerosole |
| US7727962B2 (en) | 2004-05-10 | 2010-06-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Powder comprising new compositions of oligosaccharides and methods for their preparation |
| US7723306B2 (en) | 2004-05-10 | 2010-05-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Spray-dried powder comprising at least one 1,4 O-linked saccharose-derivative and methods for their preparation |
| US7611709B2 (en) | 2004-05-10 | 2009-11-03 | Boehringer Ingelheim Pharma Gmbh And Co. Kg | 1,4 O-linked saccharose derivatives for stabilization of antibodies or antibody derivatives |
| DE102005024439A1 (de) | 2005-05-24 | 2006-12-07 | Boehringer Ingelheim International Gmbh | Zerstäuber |
| DE102005029746B4 (de) | 2005-06-24 | 2017-10-26 | Boehringer Ingelheim International Gmbh | Zerstäuber |
| ATE525105T1 (de) * | 2005-06-27 | 2011-10-15 | World Health Org | Impfstoff-vernebler |
| KR20080042085A (ko) | 2005-08-24 | 2008-05-14 | 베링거 인겔하임 인터내셔날 게엠베하 | 분무기 |
| DE102006009637A1 (de) | 2005-10-28 | 2007-05-03 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Inhalator mit Mundstück mit mikrobiologischer Schutzfunktion |
| BRPI0520704A2 (pt) * | 2005-11-30 | 2009-05-19 | Generex Pharm Inc | formulação farmacêutica absorvida oralmente e método de administração |
| EP1792660A1 (en) | 2005-12-02 | 2007-06-06 | Boehringer Ingelheim Pharma GmbH & Co. KG | Dispensing device |
| DE102006014433A1 (de) | 2006-03-27 | 2007-10-04 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Dosieraerosole für die Verabreichung von pharmazeutischen Zubereitungen |
| DE102006016903A1 (de) | 2006-04-11 | 2007-10-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Inhalator |
| DE102006016901A1 (de) | 2006-04-11 | 2007-10-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Mundstück für einen Inhalator |
| US7841338B2 (en) | 2006-04-13 | 2010-11-30 | Boehringer Ingelheim International Gmbh | Dispensing device |
| EP1844809A1 (de) | 2006-04-13 | 2007-10-17 | Boehringer Ingelheim Pharma GmbH & Co. KG | Medikamentenmagazin für einen Inhalator, sowie Mehrdosispulverinhalator |
| EP1844808A1 (de) | 2006-04-13 | 2007-10-17 | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG | Medikamenten-Ausgabevorrichtung |
| EP1844807A1 (de) | 2006-04-13 | 2007-10-17 | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG | Medikamentenmagazin, sowie Vorrichtung und Verfahren zum Öffnen desselben; Mehrdosispulverinhalator |
| DE102006022002A1 (de) | 2006-05-10 | 2007-11-15 | Boehringer Ingelheim International Gmbh | Zerstäuber und Verfahren zur Zerstäubung von Fluid |
| DE102006043637A1 (de) | 2006-05-18 | 2007-11-22 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Zerstäuber |
| US8061350B2 (en) | 2006-06-02 | 2011-11-22 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Process and device for dosing pharmaceutical agents |
| DE102007020578A1 (de) * | 2007-05-02 | 2008-11-06 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Wässrige Aerosolzubereitungen enthaltend therapeutisch wirksame Mikroorganismen oder Teile von Mikroorganismen und Verfahren zur Erzeugung entsprechender Aerosole |
| DE102007023012A1 (de) | 2007-05-15 | 2008-11-20 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Zerstäuber und Filter |
| EP2676694B1 (en) | 2007-06-15 | 2017-04-26 | Boehringer Ingelheim International GmbH | Inhaler |
| EP2011536A1 (en) | 2007-07-06 | 2009-01-07 | Boehringer Ingelheim Pharma GmbH & Co. KG | Inhaler |
| CN100593424C (zh) * | 2007-07-18 | 2010-03-10 | 北京万生药业有限责任公司 | 一种氧气湿化及输送装置 |
| DE102007033861A1 (de) | 2007-07-20 | 2009-07-02 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pulverinhalator |
| DE102007036411A1 (de) | 2007-07-20 | 2009-02-12 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pulverinhalator |
| DE102007033860A1 (de) | 2007-07-20 | 2009-01-22 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Prüfvorrichtung |
| DE102007036413A1 (de) | 2007-08-02 | 2009-02-05 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Vorrichtung und Verfahren zur Bestimmung des Feuchtegehalts eines Verpackungsmaterials |
| DE102007034156A1 (de) | 2007-07-21 | 2009-01-22 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Vorrichtung und Verfahren zur Bestimmung des Feuchtegehalts eines Verpackungsmaterials |
| DE102007052871A1 (de) | 2007-11-02 | 2009-05-07 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Kapsel zur Aufnahme von pharmazeutischen Wirkstoffformulierungen |
| DE102007058112A1 (de) | 2007-12-03 | 2009-06-04 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pulverinhalator mit Wirkstofftablette |
| EP2077132A1 (en) | 2008-01-02 | 2009-07-08 | Boehringer Ingelheim Pharma GmbH & Co. KG | Dispensing device, storage device and method for dispensing a formulation |
| EA201001453A1 (ru) | 2008-03-17 | 2011-04-29 | Бёрингер Ингельхайм Интернациональ Гмбх | Резервуар и распылитель |
| EP2135632A1 (de) | 2008-06-20 | 2009-12-23 | Boehringer Ingelheim International Gmbh | Inhalator |
| EP2198972A1 (de) | 2008-12-18 | 2010-06-23 | Boehringer Ingelheim International GmbH | Reservoir und Zerstäuber |
| WO2010076012A1 (de) | 2009-01-02 | 2010-07-08 | Boehringer Ingelheim International Gmbh | Bauteil und inhalator sowie verfahren zur herstellung eines bauteils |
| US8905017B2 (en) | 2009-03-17 | 2014-12-09 | Boehringer Ingelheim International Gmbh | Reservoir and atomizer |
| WO2010105776A1 (en) | 2009-03-17 | 2010-09-23 | Boehringer Ingelheim International Gmbh | Dispensing device, storage device and method for dispensing a formulation |
| US10011906B2 (en) | 2009-03-31 | 2018-07-03 | Beohringer Ingelheim International Gmbh | Method for coating a surface of a component |
| EP2424603B1 (de) | 2009-04-28 | 2014-12-31 | Boehringer Ingelheim International GmbH | Inhalationsvorrichtung |
| EP3508239B1 (de) | 2009-05-18 | 2020-12-23 | Boehringer Ingelheim International GmbH | Adapter, inhalationseinrichtung und zerstäuber |
| WO2010149280A1 (en) | 2009-06-25 | 2010-12-29 | Boehringer Ingelheim Vetmedica Gmbh | Inhaler |
| US8746244B2 (en) | 2009-10-02 | 2014-06-10 | Boehringer Ingelheim International Gmbh | Powder inhaler |
| EP2504051B1 (en) | 2009-11-25 | 2019-09-04 | Boehringer Ingelheim International GmbH | Nebulizer |
| US10016568B2 (en) | 2009-11-25 | 2018-07-10 | Boehringer Ingelheim International Gmbh | Nebulizer |
| JP5715640B2 (ja) | 2009-11-25 | 2015-05-13 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ネブライザ |
| EP2585151B1 (en) | 2010-06-24 | 2018-04-04 | Boehringer Ingelheim International GmbH | Nebulizer |
| EP2694220B1 (de) | 2011-04-01 | 2020-05-06 | Boehringer Ingelheim International GmbH | Medizinisches gerät mit behälter |
| US9827384B2 (en) | 2011-05-23 | 2017-11-28 | Boehringer Ingelheim International Gmbh | Nebulizer |
| WO2013152894A1 (de) | 2012-04-13 | 2013-10-17 | Boehringer Ingelheim International Gmbh | Zerstäuber mit kodiermitteln |
| CN103386125A (zh) * | 2012-05-08 | 2013-11-13 | 刘江秋 | 肾综合征出血热鼻黏膜免疫气溶胶疫苗的研制 |
| WO2015018904A1 (en) | 2013-08-09 | 2015-02-12 | Boehringer Ingelheim International Gmbh | Nebulizer |
| EP2835146B1 (en) | 2013-08-09 | 2020-09-30 | Boehringer Ingelheim International GmbH | Nebulizer |
| CN103575718A (zh) * | 2013-11-21 | 2014-02-12 | 中国人民解放军63975部队 | 用量子点荧光传感体系测定蛋白喷剂雾化效果的方法 |
| JP6580070B2 (ja) | 2014-05-07 | 2019-09-25 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 容器、ネブライザ、及び使用 |
| BR112016023932B1 (pt) | 2014-05-07 | 2022-11-29 | Boehringer Ingelheim International Gmbh | Nebulizador |
| HUE055604T2 (hu) | 2014-05-07 | 2021-12-28 | Boehringer Ingelheim Int | Porlasztó |
| CN104474534A (zh) * | 2014-12-22 | 2015-04-01 | 哈德逊（天津）生物技术有限责任公司 | 白介素-18抗病毒口腔喷剂 |
| EP3563894B1 (en) | 2018-05-04 | 2021-12-22 | Boehringer Ingelheim International GmbH | Nebulizer and container |
| JP2023543965A (ja) * | 2020-08-14 | 2023-10-19 | イスタンブル ウニヴェルシテシ レクトールルグ | 吸入経路を介するソフトミスト吸入器又は振動メッシュ式ネブライザーによるウイルス性肺疾患、急性及び／又は慢性の肺疾患治療におけるヘパリン組成物の使用 |
| CN114712336B (zh) * | 2020-12-22 | 2023-11-07 | 黄嘉若 | 一种用于肺部给药的水性气溶胶、制备方法和用途 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4153689A (en) * | 1975-06-13 | 1979-05-08 | Takeda Chemical Industries, Ltd. | Stable insulin preparation for nasal administration |
| JPS58501125A (ja) * | 1981-07-17 | 1983-07-14 | ノルデイスク・インスリンラボラトリウム | 安定な水性治療性インシユリン製剤及びその製造方法 |
| WO1983003054A1 (en) * | 1982-03-03 | 1983-09-15 | Johansen, Kristian, Betton | A proces for producing an insulin preparation |
| US4476116A (en) * | 1982-12-10 | 1984-10-09 | Syntex (U.S.A.) Inc. | Polypeptides/chelating agent nasal compositions having enhanced peptide absorption |
| DE3827121A1 (de) * | 1988-08-10 | 1990-02-15 | Hoechst Ag | Verfahren zur herstellung von des-b30-insulinen und des-b30-insulinderivaten |
| JPH05508616A (ja) * | 1989-02-23 | 1993-12-02 | ローヌー プーラン ローラー インターナショナル（ホウルディングス）インコーポレイテッド | 治療用エアロゾル剤 |
| JP2704546B2 (ja) * | 1989-04-04 | 1998-01-26 | 光利 太良 | Ａｔｌｌ治療用吸入剤 |
| SG45171A1 (en) * | 1990-03-21 | 1998-01-16 | Boehringer Ingelheim Int | Atomising devices and methods |
| US5230884A (en) * | 1990-09-11 | 1993-07-27 | University Of Wales College Of Cardiff | Aerosol formulations including proteins and peptides solubilized in reverse micelles and process for making the aerosol formulations |
| IL99699A (en) * | 1990-10-10 | 2002-04-21 | Autoimmune Inc | Drug with the option of oral, intra-intestinal, or inhaled dosing for suppression of autoimmune response associated with type I diabetes |
| NZ241954A (en) * | 1991-03-15 | 1994-01-26 | Amgen Inc | Compositions of g-csf for pulmonary administration. |
| DE4117078A1 (de) * | 1991-05-25 | 1992-11-26 | Boehringer Ingelheim Kg | Verfahren zur herstellung therapeutisch anwendbarer aerosole |
| US5888477A (en) * | 1993-01-29 | 1999-03-30 | Aradigm Corporation | Use of monomeric insulin as a means for improving the bioavailability of inhaled insulin |
| US5354934A (en) * | 1993-02-04 | 1994-10-11 | Amgen Inc. | Pulmonary administration of erythropoietin |
| CA2155933C (en) * | 1993-02-12 | 2000-04-04 | James L. Levin | Pulmonary administration of scr1 and other complement inhibitory proteins |
| ZA942073B (en) * | 1993-03-24 | 1994-10-27 | Boehringer Ingelheim Pharma | Method for inhibiting pulmonary oxygen toxicity using manganese superoxide dismutase |
| WO1995003034A1 (en) * | 1993-07-19 | 1995-02-02 | Amgen Inc. | Stabilization of aerosolized proteins |
| JPH07165613A (ja) * | 1993-10-19 | 1995-06-27 | Dot:Kk | 経鼻吸収薬物用キャリヤおよび生理活性ペプチド組成物 |
| JP3414539B2 (ja) * | 1994-05-11 | 2003-06-09 | 有限会社ドット | 経鼻吸収用組成物 |
| US5541569A (en) * | 1995-02-28 | 1996-07-30 | Jang; Huey J. | Switch having a circuit breaker |
| DE19536902A1 (de) * | 1995-10-04 | 1997-04-10 | Boehringer Ingelheim Int | Vorrichtung zur Hochdruckerzeugung in einem Fluid in Miniaturausführung |
| US5780440A (en) * | 1996-06-17 | 1998-07-14 | Protease Sciences Inc. | Treatment of pulmonary disease with protease inhibitors |
| DE19653969A1 (de) * | 1996-12-20 | 1998-06-25 | Boehringer Ingelheim Kg | Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole |
-
1997
- 1997-08-04 DE DE19733651A patent/DE19733651A1/de not_active Ceased
-
1998
- 1998-07-31 IL IL13411598A patent/IL134115A0/xx active IP Right Grant
- 1998-07-31 SK SK150-2000A patent/SK285637B6/sk not_active IP Right Cessation
- 1998-07-31 ES ES98943814T patent/ES2248915T3/es not_active Expired - Lifetime
- 1998-07-31 RS YUP-56/00A patent/RS49705B/sr unknown
- 1998-07-31 WO PCT/EP1998/004803 patent/WO1999007340A1/de not_active Application Discontinuation
- 1998-07-31 UA UA2000031252A patent/UA73076C2/uk unknown
- 1998-07-31 SI SI9830799T patent/SI1003478T1/sl unknown
- 1998-07-31 BR BR9811827-7A patent/BR9811827A/pt not_active Application Discontinuation
- 1998-07-31 KR KR1020007001230A patent/KR20010022636A/ko not_active Application Discontinuation
- 1998-07-31 AU AU91577/98A patent/AU753673B2/en not_active Ceased
- 1998-07-31 EE EEP200000065A patent/EE05053B1/xx not_active IP Right Cessation
- 1998-07-31 EA EA200000190A patent/EA002255B1/ru not_active IP Right Cessation
- 1998-07-31 HU HU0003805A patent/HUP0003805A3/hu unknown
- 1998-07-31 EP EP98943814A patent/EP1003478B1/de not_active Expired - Lifetime
- 1998-07-31 CN CNB988078953A patent/CN1177581C/zh not_active Expired - Fee Related
- 1998-07-31 AT AT98943814T patent/ATE301987T1/de active
- 1998-07-31 PL PL98338421A patent/PL338421A1/xx not_active Application Discontinuation
- 1998-07-31 TR TR2000/00312T patent/TR200000312T2/xx unknown
- 1998-07-31 CA CA002297174A patent/CA2297174A1/en not_active Abandoned
- 1998-07-31 JP JP2000506934A patent/JP2001513492A/ja active Pending
- 1998-07-31 DE DE59813014T patent/DE59813014D1/de not_active Expired - Lifetime
- 1998-07-31 DK DK98943814T patent/DK1003478T3/da active
- 1998-07-31 NZ NZ503160A patent/NZ503160A/en unknown
- 1998-07-31 ID IDW20000210A patent/ID24200A/id unknown
- 1998-07-31 PT PT98943814T patent/PT1003478E/pt unknown
- 1998-07-31 EP EP05002747A patent/EP1527771A3/de not_active Withdrawn
- 1998-08-03 UY UY25122A patent/UY25122A1/es not_active IP Right Cessation
- 1998-08-03 ZA ZA9806931A patent/ZA986931B/xx unknown
- 1998-08-03 HR HR980425A patent/HRP980425B1/xx not_active IP Right Cessation
- 1998-08-03 CO CO98044242A patent/CO4960637A1/es unknown
- 1998-08-03 MY MYPI98003548A patent/MY132852A/en unknown
- 1998-08-03 AR ARP980103825A patent/AR016581A1/es not_active Suspension/Interruption
-
1999
- 1999-03-12 TW TW087112723A patent/TWI222887B/zh not_active IP Right Cessation
-
2000
- 2000-01-18 IL IL134115A patent/IL134115A/en not_active IP Right Cessation
- 2000-02-03 NO NO20000553A patent/NO20000553L/no not_active Application Discontinuation
- 2000-02-04 BG BG104130A patent/BG64966B1/bg active Active
- 2000-10-26 HK HK00106819A patent/HK1027749A1/xx not_active IP Right Cessation
-
2002
- 2002-11-06 US US10/288,770 patent/US20030064032A1/en not_active Abandoned
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK1003478T3 (da) | Vandige aerosolpræparater indeholdende biologisk aktive makromolekyler og fremgangsmåde til fremstilling af tilsvarende aerosoler | |
| DK1036794T3 (da) | 2-Aryl-8-oxodihydropurinderivater, fremgangsmåde til fremstilling af samme, medicinske præparater indeholdende samme og mellemprodukter deraf | |
| DE69003804D1 (de) | Fentanyl enthaltende aerosolzubereitungen. | |
| DK0876332T3 (da) | Phenyleddikesyrederivater, fremgangsmåde og mellemprodukter til deres fremstilling og midler indeholdende disse | |
| DK0797431T3 (da) | Aerosolformuleringer af peptider og proteiner | |
| DK0973796T3 (da) | Fremgangsmåde til fremstilling og oprensning af et N-alkyleret aspartamderivat | |
| NO20005430D0 (no) | 1-[(1-substituerte-4-piperidinyl)metyl]-4-piperidinderivater, fremgangsmÕter for fremstilling av disse, medisinske preparater inneholdende dem, og mellomprodukter | |
| DE69530325D1 (de) | Aerosol-arzneiformulierungen | |
| DK0985697T3 (da) | Oxiranderivater og fremgangsmåde til fremstilling deraf | |
| IS5409A (is) | Útskipt karboxamídóþíasól, framleiðsla þeirra og lyfjablöndur sem innihalda þau | |
| FI973244A (fi) | Farmaseuttisia valmisteita nenänsisäiseen käyttöön | |
| DK1015444T3 (da) | Pyrimidinderivater og fremgangsmåder til fremstilling deraf | |
| HUP9802808A3 (en) | N-(4-carbamido-phenyl)-phenylglycin-amid derivatives, process for preparing them, pharmaceuticals containing them and intermediates | |
| NO973263D0 (no) | Fremgangsmåte for fremstilling og anvendelse av vandige emulsjoner | |
| NO984309L (no) | Nye imidazolidinderivater, deres fremstilling, deres anvendelse og farmas°ytiske preparater inneholdende disse | |
| DK1003383T4 (da) | Smagsforstærkende N-ethyl-p-menthan-3-carboxamidindeholdende forbindelser og fremgangsmåde til fremstilling og anvendelse deraf | |
| NO20003662D0 (no) | Syntetiske polysakkarider, fremgangsmÕte for fremstilling derav og farmasøytiske preparater inneholdende slike | |
| DE69705628D1 (de) | Chlorfluorkohlenwasserstoff freie aerosol-arzneizubereitungen enthaltend mometasonfuroat | |
| DK0842927T3 (da) | 3-Amido-chromanylsulfonyl(thio)urinstoffer, fremgangsmåder til deres fremstilling, deres anvendelse og farmaceutiske præparater med indhold deraf | |
| DK1165528T3 (da) | Hidtil ukendte morpholinoderivater, fremgangsmåde til fremstilling af disse og farmaceutiske præparater indeholdende disse | |
| KR970704417A (ko) | 친유성 히드록시산, 그의 화장제 및 약제학적 용도 및 그의 제조 방법(lipophilic hydroxylated acid, cosmetic and pharmaceutical use thereof and method for preparing same) | |
| DK1041065T3 (da) | Fremgangsmåde til isolering af urinstof under anvendelse af membraner og præparater heraf | |
| NO974932L (no) | Pesticidpreparater og fremgangsmåte for fremstilling derav | |
| DK191290A (da) | Extracellulaer exopolymer, fremgangsmaade til fremstilling af samme og farmaceutiske praeparater indeholdende exopolymeren | |
| AU2002300833A1 (en) | Aqueous aerosol preparations containing biologically active macromolecules and method for producing the corresponding aerosols |