UY25122A1 - Preparados de aerosoles acuosos que contienen macromoléculas biológicamente activas y procedimiento para la generación de aerosoles correspondientes - Google Patents

Preparados de aerosoles acuosos que contienen macromoléculas biológicamente activas y procedimiento para la generación de aerosoles correspondientes

Info

Publication number
UY25122A1
UY25122A1 UY25122A UY25122A UY25122A1 UY 25122 A1 UY25122 A1 UY 25122A1 UY 25122 A UY25122 A UY 25122A UY 25122 A UY25122 A UY 25122A UY 25122 A1 UY25122 A1 UY 25122A1
Authority
UY
Uruguay
Prior art keywords
aerosols
biologically active
aqueous
generation
preparation
Prior art date
Application number
UY25122A
Other languages
English (en)
Inventor
Christopher Meade
Herbert Lamche
Bernd Zierenberg
Original Assignee
Boehringer Ingelheim Pharma
Amp Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma, Amp Co Kg filed Critical Boehringer Ingelheim Pharma
Publication of UY25122A1 publication Critical patent/UY25122A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44—Oxidoreductases (1)
    • A61K38/446—Superoxide dismutase (1.15)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Otolaryngology (AREA)
  • Diabetes (AREA)
  • Dispersion Chemistry (AREA)
  • Zoology (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

El presente invento se refiere al preparado de 5 aerosoles acuosos que contienen macromoléculas biológicamente activas para la generación de aerosoles inhalables sin ningún gas propulsor. La misión de este invento es un procedimiento para la preparación de aerosoles inhalables con el que se puedan nebulizar, sin pérdidas escenciales de actividad, macromoléculas biológicamente activas, especialmente proteínas. El nebulizador de este invento , excento de gas propulsor, puede atomizar 15 microlitros, de manera tal que se formen gotitas inhalables menor a 10 micrómetroa, estos nebulizadores, nebulizan interferones, en otros casos ellos se nebulizan pero con pérdida de actividad. La composición a ser administrada por inhalación es un preparado acuoso, libre de propelente. La preparación contiene sustsncias activas como : orexinas, FNT-alfa y beta, eritropoyetina, anexinas, leptinas, calcitonina, insulina, etc
UY25122A 1997-08-04 1998-08-03 Preparados de aerosoles acuosos que contienen macromoléculas biológicamente activas y procedimiento para la generación de aerosoles correspondientes UY25122A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19733651A DE19733651A1 (de) 1997-08-04 1997-08-04 Wässrige Aerosolzubereitungen enthaltend biologisch aktive Markomoleküle und Verfahren zur Erzeugung entsprechender Aerosole

Publications (1)

Publication Number Publication Date
UY25122A1 true UY25122A1 (es) 2000-12-29

Family

ID=7837935

Family Applications (1)

Application Number Title Priority Date Filing Date
UY25122A UY25122A1 (es) 1997-08-04 1998-08-03 Preparados de aerosoles acuosos que contienen macromoléculas biológicamente activas y procedimiento para la generación de aerosoles correspondientes

Country Status (36)

Country Link
US (1) US20030064032A1 (es)
EP (2) EP1527771A3 (es)
JP (1) JP2001513492A (es)
KR (1) KR20010022636A (es)
CN (1) CN1177581C (es)
AR (1) AR016581A1 (es)
AT (1) ATE301987T1 (es)
AU (1) AU753673B2 (es)
BG (1) BG64966B1 (es)
BR (1) BR9811827A (es)
CA (1) CA2297174A1 (es)
CO (1) CO4960637A1 (es)
DE (2) DE19733651A1 (es)
DK (1) DK1003478T3 (es)
EA (1) EA002255B1 (es)
EE (1) EE05053B1 (es)
ES (1) ES2248915T3 (es)
HK (1) HK1027749A1 (es)
HR (1) HRP980425B1 (es)
HU (1) HUP0003805A3 (es)
ID (1) ID24200A (es)
IL (2) IL134115A0 (es)
MY (1) MY132852A (es)
NO (1) NO20000553L (es)
NZ (1) NZ503160A (es)
PL (1) PL338421A1 (es)
PT (1) PT1003478E (es)
RS (1) RS49705B (es)
SI (1) SI1003478T1 (es)
SK (1) SK285637B6 (es)
TR (1) TR200000312T2 (es)
TW (1) TWI222887B (es)
UA (1) UA73076C2 (es)
UY (1) UY25122A1 (es)
WO (1) WO1999007340A1 (es)
ZA (1) ZA986931B (es)

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Also Published As

Publication number Publication date
EP1003478A1 (de) 2000-05-31
YU5600A (sh) 2002-08-12
AR016581A1 (es) 2001-07-25
ATE301987T1 (de) 2005-09-15
EP1527771A2 (de) 2005-05-04
EE05053B1 (et) 2008-08-15
AU753673B2 (en) 2002-10-24
AU9157798A (en) 1999-03-01
DE59813014D1 (de) 2005-09-22
TR200000312T2 (tr) 2000-07-21
NO20000553D0 (no) 2000-02-03
HUP0003805A2 (en) 2001-03-28
CN1177581C (zh) 2004-12-01
NO20000553L (no) 2000-04-03
TWI222887B (en) 2004-11-01
CA2297174A1 (en) 1999-02-18
JP2001513492A (ja) 2001-09-04
RS49705B (sr) 2007-12-31
HRP980425B1 (en) 2006-10-31
EP1527771A3 (de) 2007-02-07
BR9811827A (pt) 2000-08-15
EE200000065A (et) 2000-10-16
BG64966B1 (bg) 2006-11-30
EP1003478B1 (de) 2005-08-17
DE19733651A1 (de) 1999-02-18
SI1003478T1 (sl) 2006-02-28
WO1999007340A1 (de) 1999-02-18
CO4960637A1 (es) 2000-09-25
UA73076C2 (en) 2005-06-15
PL338421A1 (en) 2000-11-06
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ES2248915T3 (es) 2006-03-16
DK1003478T3 (da) 2005-10-24
HK1027749A1 (en) 2001-01-23
EA200000190A1 (ru) 2000-10-30
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SK285637B6 (sk) 2007-05-03
BG104130A (en) 2000-09-29
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ZA986931B (en) 1999-07-05
CN1265583A (zh) 2000-09-06
PT1003478E (pt) 2005-11-30
HRP980425A2 (en) 1999-04-30
MY132852A (en) 2007-10-31
IL134115A (en) 2006-04-10
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