MX2023006136A - Composiciones y metodos de tratamiento novedosos. - Google Patents
Composiciones y metodos de tratamiento novedosos.Info
- Publication number
- MX2023006136A MX2023006136A MX2023006136A MX2023006136A MX2023006136A MX 2023006136 A MX2023006136 A MX 2023006136A MX 2023006136 A MX2023006136 A MX 2023006136A MX 2023006136 A MX2023006136 A MX 2023006136A MX 2023006136 A MX2023006136 A MX 2023006136A
- Authority
- MX
- Mexico
- Prior art keywords
- compositions
- airborne
- relates
- subject
- viral infection
- Prior art date
Links
- 208000036142 Viral infection Diseases 0.000 title abstract 6
- 230000009385 viral infection Effects 0.000 title abstract 6
- 239000000203 mixture Substances 0.000 abstract 12
- 241000700605 Viruses Species 0.000 abstract 6
- 238000000034 method Methods 0.000 abstract 3
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 abstract 2
- 239000006071 cream Substances 0.000 abstract 2
- 239000000839 emulsion Substances 0.000 abstract 2
- 239000000499 gel Substances 0.000 abstract 2
- 239000007922 nasal spray Substances 0.000 abstract 2
- 238000011321 prophylaxis Methods 0.000 abstract 2
- 238000011282 treatment Methods 0.000 abstract 2
- 230000029812 viral genome replication Effects 0.000 abstract 2
- 241000711573 Coronaviridae Species 0.000 abstract 1
- 241000127282 Middle East respiratory syndrome-related coronavirus Species 0.000 abstract 1
- 241000315672 SARS coronavirus Species 0.000 abstract 1
- 102000004338 Transferrin Human genes 0.000 abstract 1
- 108090000901 Transferrin Proteins 0.000 abstract 1
- PTFCDOFLOPIGGS-UHFFFAOYSA-N Zinc dication Chemical compound [Zn+2] PTFCDOFLOPIGGS-UHFFFAOYSA-N 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 230000000843 anti-fungal effect Effects 0.000 abstract 1
- 230000000840 anti-viral effect Effects 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 239000010619 basil oil Substances 0.000 abstract 1
- 229940018006 basil oil Drugs 0.000 abstract 1
- 239000010634 clove oil Substances 0.000 abstract 1
- 239000012141 concentrate Substances 0.000 abstract 1
- 241001493065 dsRNA viruses Species 0.000 abstract 1
- 239000010642 eucalyptus oil Substances 0.000 abstract 1
- 229940044949 eucalyptus oil Drugs 0.000 abstract 1
- 239000007789 gas Substances 0.000 abstract 1
- 239000010649 ginger oil Substances 0.000 abstract 1
- XEEYBQQBJWHFJM-UHFFFAOYSA-N iron Substances [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract 1
- 229910052742 iron Inorganic materials 0.000 abstract 1
- -1 iron ions Chemical class 0.000 abstract 1
- 229940097496 nasal spray Drugs 0.000 abstract 1
- 239000006199 nebulizer Substances 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000007921 spray Substances 0.000 abstract 1
- 239000012581 transferrin Substances 0.000 abstract 1
- 239000000341 volatile oil Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A41—WEARING APPAREL
- A41D—OUTERWEAR; PROTECTIVE GARMENTS; ACCESSORIES
- A41D13/00—Professional, industrial or sporting protective garments, e.g. surgeons' gowns or garments protecting against blows or punches
- A41D13/05—Professional, industrial or sporting protective garments, e.g. surgeons' gowns or garments protecting against blows or punches protecting only a particular body part
- A41D13/11—Protective face masks, e.g. for surgical use, or for use in foul atmospheres
- A41D13/1192—Protective face masks, e.g. for surgical use, or for use in foul atmospheres with antimicrobial agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/133—Amines having hydroxy groups, e.g. sphingosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/10—Carbonates; Bicarbonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/30—Zinc; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/40—Transferrins, e.g. lactoferrins, ovotransferrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Mycology (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Inorganic Chemistry (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Physical Education & Sports Medicine (AREA)
- Textile Engineering (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Fats And Perfumes (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
Abstract
La presente invención se refiere a una composición que comprende uno o más de aceite de clavo de olor, aceite de eucalipto, aceite de albahaca, aceite de jengibre, un extracto o componente de cualquiera de estos, o una combinación de estos, y a una composición amortiguadora que tiene un pH de 6.7 a 7.9 a una temperatura de 37 °C, tanto para su uso en el tratamiento, tratamiento profiláctico o mejora de una infección viral de transmisión aérea, como para su uso en la reducción de la replicación viral en un sujeto infectado con un virus de transmisión aérea o expuesto a un virus de transmisión aérea capaz de causar una infección viral de transmisión aérea en el sujeto. La presente invención también se refiere a una composición acuosa que comprende un amortiguador y un aceite esencial con actividad antiviral, antibacteriana o antifúngica; o que comprende un amortiguador, iones de carbonato de hidrógeno y iones de cinc; o que comprende un amortiguador, iones de carbonato de hidrógeno y transferrina y/o iones de hierro. La presente invención también se refiere a métodos para preparar las composiciones y a concentrados de las composiciones. Las composiciones se pueden usar en un método de tratamiento, tratamiento profiláctico o mejora de una infección viral de transmisión aérea en un sujeto, y un método para reducir la replicación viral en un sujeto infectado con un virus de transmisión aérea o expuesto a un virus de transmisión aérea capaz de causar una infección viral de transmisión aérea en el sujeto. Los virus de transmisión aérea incluyen virus de ARN, tales como coronavirus, tales como MERS-CoV, SARS-CoV y SARS-CoV-2. Las composiciones se pueden administrar mediante pulverizador nasal, inhalador o nebulizador, o en forma de una crema, gel o emulsión, y la invención por lo tanto también se refiere a pulverizadores nasales, inhaladores, nebulizadores, cremas, geles o emulsiones que comprenden las composiciones. Las composiciones también se pueden aplicar a una máscara u otra cubierta facial, reduciendo así el riesgo de infección viral con un virus de transmisión aérea, y la invención por lo tanto también se refiere a pulverizaciones que comprenden las composiciones. Las composiciones también se pueden usar en un receptáculo a través del cual se burbujea un gas que contiene oxígeno antes de la inhalación por un sujeto, y la invención por lo tanto también se refiere a receptáculos que contienen las composiciones.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB2018571.6A GB202018571D0 (en) | 2020-11-25 | 2020-11-25 | Viral infections |
| GBGB2020320.4A GB202020320D0 (en) | 2020-12-21 | 2020-12-21 | Viral infections |
| GBGB2105509.0A GB202105509D0 (en) | 2021-04-18 | 2021-04-18 | Viral infections |
| PCT/EP2021/068425 WO2022003200A1 (en) | 2020-07-03 | 2021-07-02 | Reduction of viral infections |
| PCT/EP2021/083029 WO2022112430A1 (en) | 2020-11-25 | 2021-11-25 | Reduction of viral infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2023006136A true MX2023006136A (es) | 2023-06-28 |
Family
ID=81755354
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2023006136A MX2023006136A (es) | 2020-11-25 | 2021-11-25 | Composiciones y metodos de tratamiento novedosos. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20240050512A1 (es) |
| EP (1) | EP4250991A1 (es) |
| JP (1) | JP2023550838A (es) |
| AU (1) | AU2021388910A1 (es) |
| IL (1) | IL303225A (es) |
| MX (1) | MX2023006136A (es) |
| TW (1) | TW202237165A (es) |
| WO (1) | WO2022112430A1 (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023027939A1 (en) * | 2021-08-22 | 2023-03-02 | Viron, Inc. | Method for preventing entry and replication of enveloped viruses |
| WO2024035526A1 (en) * | 2022-08-08 | 2024-02-15 | Viron, Inc. | Combined use of nanobody, cyclodextrin and quercetin for protection from enveloped viruses |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5863563A (en) * | 1994-10-20 | 1999-01-26 | Alphagene Inc. | Treatment of pulmonary conditions associated with insufficient secretion of surfactant |
| GB9814377D0 (en) * | 1998-07-02 | 1998-09-02 | Reckitt & Colmann Prod Ltd | Treatment of airborne microorganisms |
| US7048953B2 (en) * | 2000-04-03 | 2006-05-23 | Inhalation, Inc. | Methods and apparatus to prevent, treat and cure infections of the human respiratory system by pathogens causing severe acute respiratory syndrome (SARS) |
| US20040071757A1 (en) * | 2001-11-20 | 2004-04-15 | David Rolf | Inhalation antiviral patch |
| CN1315388C (zh) * | 2004-05-31 | 2007-05-16 | 汕头市双骏生物工程有限公司 | 一种可杀灭病毒病菌的制剂及其制备方法 |
| US20090169487A1 (en) * | 2007-12-28 | 2009-07-02 | Hedayat Kamyar Malek | Essential Oil Diffusion |
| WO2015073648A1 (en) | 2013-11-13 | 2015-05-21 | Thomas Daly | Biological buffers with wide buffering ranges |
| WO2017212422A1 (en) * | 2016-06-08 | 2017-12-14 | Novartis Consumer Health Sa | Topical compositions comprising carbomer for the treatment and prevention of viral infections and allergic conditions |
| WO2018129233A1 (en) * | 2017-01-05 | 2018-07-12 | Georgia State University Research Foundation, Inc. | Antimicrobial compositions and methods of using same |
| WO2021191886A1 (en) * | 2020-03-25 | 2021-09-30 | Eybna Technologies Ltd. | Compositions comprising terpenes and terpenoids and use thereof for preventing and treating viral-induced infections of the respiratory system |
| US20230218556A1 (en) * | 2020-05-01 | 2023-07-13 | Irazu Bio | Method for treating respiratory viral infections comprising administration of fatty acid compositions |
-
2021
- 2021-11-25 IL IL303225A patent/IL303225A/en unknown
- 2021-11-25 MX MX2023006136A patent/MX2023006136A/es unknown
- 2021-11-25 JP JP2023532329A patent/JP2023550838A/ja active Pending
- 2021-11-25 US US18/265,981 patent/US20240050512A1/en active Pending
- 2021-11-25 AU AU2021388910A patent/AU2021388910A1/en active Pending
- 2021-11-25 WO PCT/EP2021/083029 patent/WO2022112430A1/en active Application Filing
- 2021-11-25 EP EP21815214.8A patent/EP4250991A1/en active Pending
- 2021-11-25 TW TW110144033A patent/TW202237165A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TW202237165A (zh) | 2022-10-01 |
| US20240050512A1 (en) | 2024-02-15 |
| EP4250991A1 (en) | 2023-10-04 |
| JP2023550838A (ja) | 2023-12-05 |
| WO2022112430A1 (en) | 2022-06-02 |
| IL303225A (en) | 2023-07-01 |
| AU2021388910A1 (en) | 2023-06-29 |
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