HRP980425B1 - Aqueous aerosol preparations containing biologically active macromolecules and method for producing such aerosoles - Google Patents

Aqueous aerosol preparations containing biologically active macromolecules and method for producing such aerosoles

Info

Publication number
HRP980425B1
HRP980425B1 HR980425A HRP980425A HRP980425B1 HR P980425 B1 HRP980425 B1 HR P980425B1 HR 980425 A HR980425 A HR 980425A HR P980425 A HRP980425 A HR P980425A HR P980425 B1 HRP980425 B1 HR P980425B1
Authority
HR
Croatia
Prior art keywords
factor
interleukina
propellant
micrometers
aerosoles
Prior art date
Application number
HR980425A
Other languages
English (en)
Croatian (hr)
Inventor
John Montague Meade Cristopher
Zierneberg Bernd
Lamche Herbert
Original Assignee
Boehringer Ingelheim Pharma Gmbh & Co. Kg.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma Gmbh & Co. Kg. filed Critical Boehringer Ingelheim Pharma Gmbh & Co. Kg.
Publication of HRP980425A2 publication Critical patent/HRP980425A2/hr
Publication of HRP980425B1 publication Critical patent/HRP980425B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44—Oxidoreductases (1)
    • A61K38/446—Superoxide dismutase (1.15)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Pulmonology (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HR980425A 1997-08-04 1998-08-03 Aqueous aerosol preparations containing biologically active macromolecules and method for producing such aerosoles HRP980425B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19733651A DE19733651A1 (de) 1997-08-04 1997-08-04 Wässrige Aerosolzubereitungen enthaltend biologisch aktive Markomoleküle und Verfahren zur Erzeugung entsprechender Aerosole

Publications (2)

Publication Number Publication Date
HRP980425A2 HRP980425A2 (en) 1999-04-30
HRP980425B1 true HRP980425B1 (en) 2006-10-31

Family

ID=7837935

Family Applications (1)

Application Number Title Priority Date Filing Date
HR980425A HRP980425B1 (en) 1997-08-04 1998-08-03 Aqueous aerosol preparations containing biologically active macromolecules and method for producing such aerosoles

Country Status (36)

Country Link
US (1) US20030064032A1 (bg)
EP (2) EP1003478B1 (bg)
JP (1) JP2001513492A (bg)
KR (1) KR20010022636A (bg)
CN (1) CN1177581C (bg)
AR (1) AR016581A1 (bg)
AT (1) ATE301987T1 (bg)
AU (1) AU753673B2 (bg)
BG (1) BG64966B1 (bg)
BR (1) BR9811827A (bg)
CA (1) CA2297174A1 (bg)
CO (1) CO4960637A1 (bg)
DE (2) DE19733651A1 (bg)
DK (1) DK1003478T3 (bg)
EA (1) EA002255B1 (bg)
EE (1) EE05053B1 (bg)
ES (1) ES2248915T3 (bg)
HK (1) HK1027749A1 (bg)
HR (1) HRP980425B1 (bg)
HU (1) HUP0003805A3 (bg)
ID (1) ID24200A (bg)
IL (2) IL134115A0 (bg)
MY (1) MY132852A (bg)
NO (1) NO20000553L (bg)
NZ (1) NZ503160A (bg)
PL (1) PL338421A1 (bg)
PT (1) PT1003478E (bg)
RS (1) RS49705B (bg)
SI (1) SI1003478T1 (bg)
SK (1) SK285637B6 (bg)
TR (1) TR200000312T2 (bg)
TW (1) TWI222887B (bg)
UA (1) UA73076C2 (bg)
UY (1) UY25122A1 (bg)
WO (1) WO1999007340A1 (bg)
ZA (1) ZA986931B (bg)

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US7727962B2 (en) 2004-05-10 2010-06-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Powder comprising new compositions of oligosaccharides and methods for their preparation
DE102005024439A1 (de) 2005-05-24 2006-12-07 Boehringer Ingelheim International Gmbh Zerstäuber
DE102005029746B4 (de) 2005-06-24 2017-10-26 Boehringer Ingelheim International Gmbh Zerstäuber
CN101247845B (zh) * 2005-06-27 2013-04-24 世界卫生组织 疫苗喷雾器
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DE102006043637A1 (de) 2006-05-18 2007-11-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Zerstäuber
US8061350B2 (en) 2006-06-02 2011-11-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Process and device for dosing pharmaceutical agents
DE102007020578A1 (de) 2007-05-02 2008-11-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Wässrige Aerosolzubereitungen enthaltend therapeutisch wirksame Mikroorganismen oder Teile von Mikroorganismen und Verfahren zur Erzeugung entsprechender Aerosole
DE102007023012A1 (de) 2007-05-15 2008-11-20 Boehringer Ingelheim Pharma Gmbh & Co. Kg Zerstäuber und Filter
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EP2011536A1 (en) 2007-07-06 2009-01-07 Boehringer Ingelheim Pharma GmbH & Co. KG Inhaler
CN100593424C (zh) * 2007-07-18 2010-03-10 北京万生药业有限责任公司 一种氧气湿化及输送装置
DE102007033861A1 (de) 2007-07-20 2009-07-02 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverinhalator
DE102007033860A1 (de) 2007-07-20 2009-01-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Prüfvorrichtung
DE102007036411A1 (de) 2007-07-20 2009-02-12 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverinhalator
DE102007036413A1 (de) 2007-08-02 2009-02-05 Boehringer Ingelheim Pharma Gmbh & Co. Kg Vorrichtung und Verfahren zur Bestimmung des Feuchtegehalts eines Verpackungsmaterials
DE102007034156A1 (de) 2007-07-21 2009-01-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Vorrichtung und Verfahren zur Bestimmung des Feuchtegehalts eines Verpackungsmaterials
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DE102007058112A1 (de) 2007-12-03 2009-06-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverinhalator mit Wirkstofftablette
EP2077132A1 (en) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
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US10011906B2 (en) 2009-03-31 2018-07-03 Beohringer Ingelheim International Gmbh Method for coating a surface of a component
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EP2694220B1 (de) 2011-04-01 2020-05-06 Boehringer Ingelheim International GmbH Medizinisches gerät mit behälter
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WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
CN103386125A (zh) * 2012-05-08 2013-11-13 刘江秋 肾综合征出血热鼻黏膜免疫气溶胶疫苗的研制
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CN103575718A (zh) * 2013-11-21 2014-02-12 中国人民解放军63975部队 用量子点荧光传感体系测定蛋白喷剂雾化效果的方法
ES2874029T3 (es) 2014-05-07 2021-11-04 Boehringer Ingelheim Int Nebulizador
ES2954961T3 (es) 2014-05-07 2023-11-27 Boehringer Ingelheim Int Unidad, nebulizador y método
UA121114C2 (uk) 2014-05-07 2020-04-10 Бьорінгер Інгельхайм Інтернаціональ Гмбх Небулайзер, індикаторний пристрій і контейнер
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CN114712336B (zh) * 2020-12-22 2023-11-07 黄嘉若 一种用于肺部给药的水性气溶胶、制备方法和用途

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Also Published As

Publication number Publication date
DE59813014D1 (de) 2005-09-22
CN1177581C (zh) 2004-12-01
AR016581A1 (es) 2001-07-25
SK285637B6 (sk) 2007-05-03
EA002255B1 (ru) 2002-02-28
DK1003478T3 (da) 2005-10-24
AU9157798A (en) 1999-03-01
HUP0003805A2 (en) 2001-03-28
EP1003478B1 (de) 2005-08-17
NZ503160A (en) 2001-12-21
HUP0003805A3 (en) 2002-04-29
AU753673B2 (en) 2002-10-24
JP2001513492A (ja) 2001-09-04
KR20010022636A (ko) 2001-03-26
IL134115A0 (en) 2001-04-30
ES2248915T3 (es) 2006-03-16
ATE301987T1 (de) 2005-09-15
CN1265583A (zh) 2000-09-06
WO1999007340A1 (de) 1999-02-18
PL338421A1 (en) 2000-11-06
BR9811827A (pt) 2000-08-15
EP1003478A1 (de) 2000-05-31
EP1527771A3 (de) 2007-02-07
CO4960637A1 (es) 2000-09-25
US20030064032A1 (en) 2003-04-03
IL134115A (en) 2006-04-10
HK1027749A1 (en) 2001-01-23
UA73076C2 (en) 2005-06-15
UY25122A1 (es) 2000-12-29
RS49705B (sr) 2007-12-31
HRP980425A2 (en) 1999-04-30
PT1003478E (pt) 2005-11-30
EA200000190A1 (ru) 2000-10-30
NO20000553D0 (no) 2000-02-03
NO20000553L (no) 2000-04-03
TWI222887B (en) 2004-11-01
ID24200A (id) 2000-07-13
TR200000312T2 (tr) 2000-07-21
BG104130A (bg) 2000-09-29
DE19733651A1 (de) 1999-02-18
CA2297174A1 (en) 1999-02-18
EP1527771A2 (de) 2005-05-04
SK1502000A3 (en) 2000-07-11
ZA986931B (en) 1999-07-05
EE05053B1 (et) 2008-08-15
MY132852A (en) 2007-10-31
YU5600A (sh) 2002-08-12
EE200000065A (et) 2000-10-16
SI1003478T1 (sl) 2006-02-28
BG64966B1 (bg) 2006-11-30

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