HK1027749A1 - Aqueous aerosol preparations containing biologically active macromolecules and method for producing the corresponding aerosols. - Google Patents

Aqueous aerosol preparations containing biologically active macromolecules and method for producing the corresponding aerosols.

Info

Publication number
HK1027749A1
HK1027749A1 HK00106819A HK00106819A HK1027749A1 HK 1027749 A1 HK1027749 A1 HK 1027749A1 HK 00106819 A HK00106819 A HK 00106819A HK 00106819 A HK00106819 A HK 00106819A HK 1027749 A1 HK1027749 A1 HK 1027749A1
Authority
HK
Hong Kong
Prior art keywords
producing
biologically active
preparations containing
aerosol preparations
aqueous aerosol
Prior art date
Application number
HK00106819A
Other languages
English (en)
Inventor
Herbert Lamche
Christopher John Montagu Meade
Bernd Zierenberg
Ralph Christian Reimholz
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of HK1027749A1 publication Critical patent/HK1027749A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44Oxidoreductases (1)
    • A61K38/446Superoxide dismutase (1.15)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Zoology (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
HK00106819A 1997-08-04 2000-10-26 Aqueous aerosol preparations containing biologically active macromolecules and method for producing the corresponding aerosols. HK1027749A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19733651A DE19733651A1 (de) 1997-08-04 1997-08-04 Wässrige Aerosolzubereitungen enthaltend biologisch aktive Markomoleküle und Verfahren zur Erzeugung entsprechender Aerosole
PCT/EP1998/004803 WO1999007340A1 (de) 1997-08-04 1998-07-31 Wässrige aerosolzubereitungen enthaltend biologisch aktive makromoleküle und verfahren zur erzeugung entsprechender aerosole

Publications (1)

Publication Number Publication Date
HK1027749A1 true HK1027749A1 (en) 2001-01-23

Family

ID=7837935

Family Applications (1)

Application Number Title Priority Date Filing Date
HK00106819A HK1027749A1 (en) 1997-08-04 2000-10-26 Aqueous aerosol preparations containing biologically active macromolecules and method for producing the corresponding aerosols.

Country Status (36)

Country Link
US (1) US20030064032A1 (bg)
EP (2) EP1003478B1 (bg)
JP (1) JP2001513492A (bg)
KR (1) KR20010022636A (bg)
CN (1) CN1177581C (bg)
AR (1) AR016581A1 (bg)
AT (1) ATE301987T1 (bg)
AU (1) AU753673B2 (bg)
BG (1) BG64966B1 (bg)
BR (1) BR9811827A (bg)
CA (1) CA2297174A1 (bg)
CO (1) CO4960637A1 (bg)
DE (2) DE19733651A1 (bg)
DK (1) DK1003478T3 (bg)
EA (1) EA002255B1 (bg)
EE (1) EE05053B1 (bg)
ES (1) ES2248915T3 (bg)
HK (1) HK1027749A1 (bg)
HR (1) HRP980425B1 (bg)
HU (1) HUP0003805A3 (bg)
ID (1) ID24200A (bg)
IL (2) IL134115A0 (bg)
MY (1) MY132852A (bg)
NO (1) NO20000553L (bg)
NZ (1) NZ503160A (bg)
PL (1) PL338421A1 (bg)
PT (1) PT1003478E (bg)
RS (1) RS49705B (bg)
SI (1) SI1003478T1 (bg)
SK (1) SK285637B6 (bg)
TR (1) TR200000312T2 (bg)
TW (1) TWI222887B (bg)
UA (1) UA73076C2 (bg)
UY (1) UY25122A1 (bg)
WO (1) WO1999007340A1 (bg)
ZA (1) ZA986931B (bg)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030215396A1 (en) 1999-09-15 2003-11-20 Boehringer Ingelheim Pharma Kg Method for the production of propellant gas-free aerosols from aqueous medicament preparations
US7963955B2 (en) 1998-02-27 2011-06-21 Boehringer Ingelheim International Gmbh Container for a medicinal liquid
SE9801495D0 (sv) * 1998-04-28 1998-04-28 Astra Ab Protein formulationa
US20060171899A1 (en) * 1998-12-10 2006-08-03 Akwete Adjei Water-stabilized aerosol formulation system and method of making
RU2140285C1 (ru) * 1999-01-25 1999-10-27 Гапонюк Петр Яковлевич Противовирусное средство - капли в нос "гриппферон"
US6350432B1 (en) * 1999-03-19 2002-02-26 Generex Pharmaceuticals Incorporated Pressurized container having an aerosolized pharmaceutical composition
NZ519403A (en) * 2001-06-21 2005-03-24 Pfizer Prod Inc Use of insulin in a medicament to reduce weight gain in a diabetic patient who is using exogenous insulin to control blood sugar levels
DE102004001451A1 (de) 2004-01-08 2005-08-11 Boehringer Ingelheim International Gmbh Vorrichtung zum Haltern eines fluidischen Bauteiles
DE102004011381A1 (de) 2004-03-05 2005-09-15 Boehringer Ingelheim Pharma Gmbh & Co. Kg Impaktionsdüse für treibgasbetriebene Dosieraerosole
US7723306B2 (en) 2004-05-10 2010-05-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Spray-dried powder comprising at least one 1,4 O-linked saccharose-derivative and methods for their preparation
US7611709B2 (en) 2004-05-10 2009-11-03 Boehringer Ingelheim Pharma Gmbh And Co. Kg 1,4 O-linked saccharose derivatives for stabilization of antibodies or antibody derivatives
US7727962B2 (en) 2004-05-10 2010-06-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Powder comprising new compositions of oligosaccharides and methods for their preparation
DE102005024439A1 (de) 2005-05-24 2006-12-07 Boehringer Ingelheim International Gmbh Zerstäuber
DE102005029746B4 (de) 2005-06-24 2017-10-26 Boehringer Ingelheim International Gmbh Zerstäuber
CN101247845B (zh) * 2005-06-27 2013-04-24 世界卫生组织 疫苗喷雾器
BRPI0614852B1 (pt) 2005-08-24 2019-06-18 Boehringer Ingelheim International Gmbh Pulverizador
DE102006009637A1 (de) 2005-10-28 2007-05-03 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator mit Mundstück mit mikrobiologischer Schutzfunktion
AP2008004447A0 (en) * 2005-11-30 2008-04-30 Generex Pharm Inc Orally absorbed pharmaceutical formulation and method of administration
EP1792660A1 (en) 2005-12-02 2007-06-06 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device
DE102006014433A1 (de) 2006-03-27 2007-10-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Dosieraerosole für die Verabreichung von pharmazeutischen Zubereitungen
DE102006016901A1 (de) 2006-04-11 2007-10-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Mundstück für einen Inhalator
DE102006016903A1 (de) 2006-04-11 2007-10-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator
EP1844808A1 (de) 2006-04-13 2007-10-17 BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG Medikamenten-Ausgabevorrichtung
EP1844807A1 (de) 2006-04-13 2007-10-17 BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG Medikamentenmagazin, sowie Vorrichtung und Verfahren zum Öffnen desselben; Mehrdosispulverinhalator
EP1844809A1 (de) 2006-04-13 2007-10-17 Boehringer Ingelheim Pharma GmbH & Co. KG Medikamentenmagazin für einen Inhalator, sowie Mehrdosispulverinhalator
US7841338B2 (en) 2006-04-13 2010-11-30 Boehringer Ingelheim International Gmbh Dispensing device
DE102006022002A1 (de) 2006-05-10 2007-11-15 Boehringer Ingelheim International Gmbh Zerstäuber und Verfahren zur Zerstäubung von Fluid
DE102006043637A1 (de) 2006-05-18 2007-11-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Zerstäuber
US8061350B2 (en) 2006-06-02 2011-11-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Process and device for dosing pharmaceutical agents
DE102007020578A1 (de) * 2007-05-02 2008-11-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Wässrige Aerosolzubereitungen enthaltend therapeutisch wirksame Mikroorganismen oder Teile von Mikroorganismen und Verfahren zur Erzeugung entsprechender Aerosole
DE102007023012A1 (de) 2007-05-15 2008-11-20 Boehringer Ingelheim Pharma Gmbh & Co. Kg Zerstäuber und Filter
JP5504156B2 (ja) 2007-06-15 2014-05-28 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 吸入器
EP2011536A1 (en) 2007-07-06 2009-01-07 Boehringer Ingelheim Pharma GmbH & Co. KG Inhaler
CN100593424C (zh) * 2007-07-18 2010-03-10 北京万生药业有限责任公司 一种氧气湿化及输送装置
DE102007033860A1 (de) 2007-07-20 2009-01-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Prüfvorrichtung
DE102007033861A1 (de) 2007-07-20 2009-07-02 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverinhalator
DE102007036411A1 (de) 2007-07-20 2009-02-12 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverinhalator
DE102007036413A1 (de) 2007-08-02 2009-02-05 Boehringer Ingelheim Pharma Gmbh & Co. Kg Vorrichtung und Verfahren zur Bestimmung des Feuchtegehalts eines Verpackungsmaterials
DE102007034156A1 (de) 2007-07-21 2009-01-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Vorrichtung und Verfahren zur Bestimmung des Feuchtegehalts eines Verpackungsmaterials
DE102007052871A1 (de) 2007-11-02 2009-05-07 Boehringer Ingelheim Pharma Gmbh & Co. Kg Kapsel zur Aufnahme von pharmazeutischen Wirkstoffformulierungen
DE102007058112A1 (de) 2007-12-03 2009-06-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverinhalator mit Wirkstofftablette
EP2077132A1 (en) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
KR20110003495A (ko) 2008-03-17 2011-01-12 베링거 인겔하임 인터내셔날 게엠베하 저장조 및 분무기
EP2135632A1 (de) 2008-06-20 2009-12-23 Boehringer Ingelheim International Gmbh Inhalator
EP2198972A1 (de) 2008-12-18 2010-06-23 Boehringer Ingelheim International GmbH Reservoir und Zerstäuber
WO2010076012A1 (de) 2009-01-02 2010-07-08 Boehringer Ingelheim International Gmbh Bauteil und inhalator sowie verfahren zur herstellung eines bauteils
WO2010105776A1 (en) 2009-03-17 2010-09-23 Boehringer Ingelheim International Gmbh Dispensing device, storage device and method for dispensing a formulation
EP2408571B1 (de) 2009-03-17 2015-09-16 Boehringer Ingelheim International GmbH Reservoir und zerstäuber
EP2414560B1 (de) 2009-03-31 2013-10-23 Boehringer Ingelheim International GmbH Verfahren zur beschichtung einer oberfläche eines bauteils
JP5812354B2 (ja) 2009-04-28 2015-11-11 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 吸入器具
WO2010133294A2 (de) 2009-05-18 2010-11-25 Boehringer Ingelheim International Gmbh Adapter, inhalationseinrichtung und zerstäuber
CN104799969B (zh) 2009-06-25 2018-11-06 贝林格尔·英格海姆维特梅迪卡有限公司 吸入器
US8746244B2 (en) 2009-10-02 2014-06-10 Boehringer Ingelheim International Gmbh Powder inhaler
JP5658268B2 (ja) 2009-11-25 2015-01-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
CN102686260B (zh) 2009-11-25 2014-10-01 贝林格尔.英格海姆国际有限公司 喷雾器
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
US9943654B2 (en) 2010-06-24 2018-04-17 Boehringer Ingelheim International Gmbh Nebulizer
WO2012130757A1 (de) 2011-04-01 2012-10-04 Boehringer Ingelheim International Gmbh Medizinisches gerät mit behälter
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
CN103386125A (zh) * 2012-05-08 2013-11-13 刘江秋 肾综合征出血热鼻黏膜免疫气溶胶疫苗的研制
ES2836977T3 (es) 2013-08-09 2021-06-28 Boehringer Ingelheim Int Nebulizador
US9744313B2 (en) 2013-08-09 2017-08-29 Boehringer Ingelheim International Gmbh Nebulizer
CN103575718A (zh) * 2013-11-21 2014-02-12 中国人民解放军63975部队 用量子点荧光传感体系测定蛋白喷剂雾化效果的方法
ES2874029T3 (es) 2014-05-07 2021-11-04 Boehringer Ingelheim Int Nebulizador
EP3139979B1 (en) 2014-05-07 2023-07-05 Boehringer Ingelheim International GmbH Unit, nebulizer and method
UA121114C2 (uk) 2014-05-07 2020-04-10 Бьорінгер Інгельхайм Інтернаціональ Гмбх Небулайзер, індикаторний пристрій і контейнер
CN104474534A (zh) * 2014-12-22 2015-04-01 哈德逊(天津)生物技术有限责任公司 白介素-18抗病毒口腔喷剂
EP3563894B1 (en) * 2018-05-04 2021-12-22 Boehringer Ingelheim International GmbH Nebulizer and container
US20240009227A1 (en) * 2020-08-14 2024-01-11 Istanbul Universitesi Rektorlugu Use of a heparin composition in the treatment of viral lung diseases, acute and/or chronic lung diseases by soft mist inhaler or vibration mesh technology nebulizer through inhalation route
CN114712336B (zh) * 2020-12-22 2023-11-07 黄嘉若 一种用于肺部给药的水性气溶胶、制备方法和用途

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4153689A (en) * 1975-06-13 1979-05-08 Takeda Chemical Industries, Ltd. Stable insulin preparation for nasal administration
WO1983000288A1 (en) * 1981-07-17 1983-02-03 Balschmidt, Per A stable aqueous, therapeutic insulin preparation and a process for preparing it
ES520249A0 (es) * 1982-03-03 1984-04-16 Nordisk Insulinlab Procedimiento de producir preparaciones de insulina.
US4476116A (en) * 1982-12-10 1984-10-09 Syntex (U.S.A.) Inc. Polypeptides/chelating agent nasal compositions having enhanced peptide absorption
DE3827121A1 (de) * 1988-08-10 1990-02-15 Hoechst Ag Verfahren zur herstellung von des-b30-insulinen und des-b30-insulinderivaten
CA2050905A1 (en) * 1989-02-23 1990-08-24 George R. Felt Therapeutic aerosol formulations
JP2704546B2 (ja) * 1989-04-04 1998-01-26 光利 太良 Atll治療用吸入剤
SG45171A1 (en) * 1990-03-21 1998-01-16 Boehringer Ingelheim Int Atomising devices and methods
US5230884A (en) * 1990-09-11 1993-07-27 University Of Wales College Of Cardiff Aerosol formulations including proteins and peptides solubilized in reverse micelles and process for making the aerosol formulations
IL99699A (en) * 1990-10-10 2002-04-21 Autoimmune Inc Drug with the option of oral, intra-intestinal, or inhaled dosing for suppression of autoimmune response associated with type I diabetes
NZ241954A (en) * 1991-03-15 1994-01-26 Amgen Inc Compositions of g-csf for pulmonary administration.
DE4117078A1 (de) * 1991-05-25 1992-11-26 Boehringer Ingelheim Kg Verfahren zur herstellung therapeutisch anwendbarer aerosole
US5888477A (en) * 1993-01-29 1999-03-30 Aradigm Corporation Use of monomeric insulin as a means for improving the bioavailability of inhaled insulin
US5354934A (en) * 1993-02-04 1994-10-11 Amgen Inc. Pulmonary administration of erythropoietin
JP3689422B2 (ja) * 1993-02-12 2005-08-31 アーヴァント イミュノセラピューティクス インコーポレイテッド sCR1およびその他の補体阻害蛋白の肺内投与
IL109112A0 (en) * 1993-03-24 1994-06-24 Boehringer Ingelheim Pharma Pharmaceutical compositions containing human manganese superoxide dismutase
CA2167538A1 (en) * 1993-07-19 1995-02-02 Tsutomu Arakawa Stabilization of aerosolized proteins
JPH07165613A (ja) * 1993-10-19 1995-06-27 Dot:Kk 経鼻吸収薬物用キャリヤおよび生理活性ペプチド組成物
JP3414539B2 (ja) * 1994-05-11 2003-06-09 有限会社ドット 経鼻吸収用組成物
US5541569A (en) * 1995-02-28 1996-07-30 Jang; Huey J. Switch having a circuit breaker
DE19536902A1 (de) * 1995-10-04 1997-04-10 Boehringer Ingelheim Int Vorrichtung zur Hochdruckerzeugung in einem Fluid in Miniaturausführung
US5780440A (en) * 1996-06-17 1998-07-14 Protease Sciences Inc. Treatment of pulmonary disease with protease inhibitors
DE19653969A1 (de) * 1996-12-20 1998-06-25 Boehringer Ingelheim Kg Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole

Also Published As

Publication number Publication date
JP2001513492A (ja) 2001-09-04
IL134115A (en) 2006-04-10
NZ503160A (en) 2001-12-21
MY132852A (en) 2007-10-31
US20030064032A1 (en) 2003-04-03
ATE301987T1 (de) 2005-09-15
BG104130A (bg) 2000-09-29
DK1003478T3 (da) 2005-10-24
RS49705B (sr) 2007-12-31
EE200000065A (et) 2000-10-16
EE05053B1 (et) 2008-08-15
EA200000190A1 (ru) 2000-10-30
EP1003478B1 (de) 2005-08-17
BR9811827A (pt) 2000-08-15
NO20000553D0 (no) 2000-02-03
WO1999007340A1 (de) 1999-02-18
EP1527771A3 (de) 2007-02-07
SK1502000A3 (en) 2000-07-11
HRP980425B1 (en) 2006-10-31
CN1265583A (zh) 2000-09-06
AU9157798A (en) 1999-03-01
SI1003478T1 (sl) 2006-02-28
HUP0003805A3 (en) 2002-04-29
UA73076C2 (en) 2005-06-15
EP1003478A1 (de) 2000-05-31
SK285637B6 (sk) 2007-05-03
TR200000312T2 (tr) 2000-07-21
BG64966B1 (bg) 2006-11-30
UY25122A1 (es) 2000-12-29
AU753673B2 (en) 2002-10-24
YU5600A (sh) 2002-08-12
IL134115A0 (en) 2001-04-30
PL338421A1 (en) 2000-11-06
DE59813014D1 (de) 2005-09-22
EA002255B1 (ru) 2002-02-28
ZA986931B (en) 1999-07-05
DE19733651A1 (de) 1999-02-18
CN1177581C (zh) 2004-12-01
PT1003478E (pt) 2005-11-30
CO4960637A1 (es) 2000-09-25
KR20010022636A (ko) 2001-03-26
NO20000553L (no) 2000-04-03
TWI222887B (en) 2004-11-01
EP1527771A2 (de) 2005-05-04
AR016581A1 (es) 2001-07-25
ES2248915T3 (es) 2006-03-16
HRP980425A2 (en) 1999-04-30
ID24200A (id) 2000-07-13
CA2297174A1 (en) 1999-02-18
HUP0003805A2 (en) 2001-03-28

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