HRP980258B1 - New triazole derivatives, process for the preparation thereof and pharmaceutical preparations containing them - Google Patents

New triazole derivatives, process for the preparation thereof and pharmaceutical preparations containing them

Info

Publication number
HRP980258B1
HRP980258B1 HR980258A HRP980258A HRP980258B1 HR P980258 B1 HRP980258 B1 HR P980258B1 HR 980258 A HR980258 A HR 980258A HR P980258 A HRP980258 A HR P980258A HR P980258 B1 HRP980258 B1 HR P980258B1
Authority
HR
Croatia
Prior art keywords
preparation
pharmaceutical preparations
preparations containing
triazole derivatives
new triazole
Prior art date
Application number
HR980258A
Inventor
Eric Bignon
Jean-Pierre Bras
Paul De Cointet
Pierre Despeyroux
Daniel Frehel
Danielle Gully
Original Assignee
Sanofi Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo filed Critical Sanofi Synthelabo
Publication of HRP980258A2 publication Critical patent/HRP980258A2/en
Publication of HRP980258B1 publication Critical patent/HRP980258B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/14—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
HR980258A 1997-05-13 1998-05-13 New triazole derivatives, process for the preparation thereof and pharmaceutical preparations containing them HRP980258B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9705850A FR2763337B1 (en) 1997-05-13 1997-05-13 NOVEL TRIAZOLE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Publications (2)

Publication Number Publication Date
HRP980258A2 HRP980258A2 (en) 1999-02-28
HRP980258B1 true HRP980258B1 (en) 2002-08-31

Family

ID=9506830

Family Applications (1)

Application Number Title Priority Date Filing Date
HR980258A HRP980258B1 (en) 1997-05-13 1998-05-13 New triazole derivatives, process for the preparation thereof and pharmaceutical preparations containing them

Country Status (35)

Country Link
EP (1) EP0984960B1 (en)
JP (1) JP2001524980A (en)
KR (1) KR20010012541A (en)
CN (1) CN1263528A (en)
AR (1) AR011729A1 (en)
AT (1) ATE232207T1 (en)
AU (1) AU725530B2 (en)
BR (1) BR9811465A (en)
CA (1) CA2289573A1 (en)
CO (1) CO4940485A1 (en)
CZ (1) CZ289484B6 (en)
DE (1) DE69811223T2 (en)
DK (1) DK0984960T3 (en)
DZ (1) DZ2486A1 (en)
EE (1) EE9900524A (en)
ES (1) ES2190081T3 (en)
FR (1) FR2763337B1 (en)
GT (1) GT199800068A (en)
HR (1) HRP980258B1 (en)
HU (1) HUP0002763A3 (en)
ID (1) ID22911A (en)
IL (1) IL132903A0 (en)
IS (1) IS5235A (en)
NO (1) NO995513L (en)
NZ (1) NZ500637A (en)
PL (1) PL336772A1 (en)
RU (1) RU2175323C2 (en)
SI (1) SI0984960T1 (en)
SK (1) SK154299A3 (en)
TR (1) TR199902795T2 (en)
TW (1) TW396155B (en)
UY (1) UY24997A1 (en)
WO (1) WO1998051686A1 (en)
YU (1) YU57999A (en)
ZA (1) ZA983997B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2802530B1 (en) * 1999-12-17 2002-02-22 Sanofi Synthelabo NOVEL BRANCHED SUBSTITUTED AMINO DERIVATIVES OF 3-AMINO-1-PHENYL-1H [1,2,4] TRIAZOLE, METHODS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
CA2420727A1 (en) * 2000-10-26 2002-05-02 Sanofi-Synthelabo Triazole derivatives and pharmaceutical compositions comprising them
FR2815963B1 (en) * 2000-10-26 2003-02-28 Sanofi Synthelabo NOVEL TRIAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
HUP0004741A2 (en) * 2000-11-28 2002-12-28 Sanofi-Synthelabo Chemical process for the preparation of thiazole derivatives and new intermediate
JP2005507932A (en) * 2001-10-12 2005-03-24 バイエル・フアーマシユーチカルズ・コーポレーシヨン Phenyl-substituted 5-membered nitrogen-containing heterocycles for the treatment of obesity
EP1314733A1 (en) 2001-11-22 2003-05-28 Aventis Pharma Deutschland GmbH Indole-2-carboxamides as factor Xa inhibitors
EP1479677A1 (en) * 2003-05-19 2004-11-24 Aventis Pharma Deutschland GmbH New indole derivatives as factor xa inhibitors
EP1532980A1 (en) * 2003-11-24 2005-05-25 Novo Nordisk A/S N-heteroaryl indole carboxamides and analogues thereof, for use as glucokinase activators in the treatment of diabetes
GB0403038D0 (en) * 2004-02-11 2004-03-17 Novartis Ag Organic compounds
CA2676222A1 (en) * 2007-01-26 2008-07-31 Merck & Co., Inc. Substituted aminopyrimidines as cholecystokinin-1 receptor modulators
US8703761B2 (en) * 2008-07-15 2014-04-22 Novartis Ag Organic compounds
CN102414207B (en) * 2009-06-09 2015-09-30 埃科特莱茵药品有限公司 Fluorinated aminotriazole derivatives
WO2011048176A1 (en) * 2009-10-22 2011-04-28 Henkel Ag & Co. Kgaa Agent for treating keratin-containing fibres, containing a non-ionic starch modified by propylene oxide and an additional film-forming and/or stabilising non-ionic polymer
CN106928147A (en) * 2017-03-14 2017-07-07 华东师范大学 Tricyclic diterpene analog and preparation method thereof and its application in antiprostate cancer is prepared
CN107271623A (en) * 2017-07-27 2017-10-20 青岛啤酒股份有限公司 Beer potableness evaluation method based on human body satiety
CA3156985A1 (en) 2019-10-07 2021-04-15 Kallyope, Inc. Gpr119 agonists

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2701708B1 (en) * 1993-02-19 1995-05-19 Sanofi Elf Polysubstituted 2-amido-4-phenylthiazole derivatives, process for their preparation, pharmaceutical composition and use of these derivatives for the preparation of a medicament.
FR2703995B1 (en) * 1993-04-16 1995-07-21 Sanofi Elf 5-ACYLAMINO 1,2,4-THIADIAZOLES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.

Also Published As

Publication number Publication date
GT199800068A (en) 1999-11-11
CZ400699A3 (en) 2000-02-16
IL132903A0 (en) 2001-03-19
UY24997A1 (en) 2000-10-31
TW396155B (en) 2000-07-01
DE69811223D1 (en) 2003-03-13
YU57999A (en) 2002-06-19
HUP0002763A2 (en) 2001-06-28
EP0984960B1 (en) 2003-02-05
CO4940485A1 (en) 2000-07-24
SI0984960T1 (en) 2003-06-30
JP2001524980A (en) 2001-12-04
IS5235A (en) 1999-10-29
HUP0002763A3 (en) 2002-05-28
FR2763337A1 (en) 1998-11-20
WO1998051686A1 (en) 1998-11-19
DZ2486A1 (en) 2003-02-01
NO995513L (en) 2000-01-12
TR199902795T2 (en) 2000-02-21
ATE232207T1 (en) 2003-02-15
ID22911A (en) 1999-12-16
PL336772A1 (en) 2000-07-17
KR20010012541A (en) 2001-02-15
HRP980258A2 (en) 1999-02-28
BR9811465A (en) 2000-09-12
AU7659998A (en) 1998-12-08
CA2289573A1 (en) 1998-11-19
NO995513D0 (en) 1999-11-11
EE9900524A (en) 2000-06-15
AU725530B2 (en) 2000-10-12
EP0984960A1 (en) 2000-03-15
SK154299A3 (en) 2000-05-16
ZA983997B (en) 1999-11-12
DE69811223T2 (en) 2003-11-27
CZ289484B6 (en) 2002-01-16
FR2763337B1 (en) 1999-08-20
NZ500637A (en) 2000-11-24
ES2190081T3 (en) 2003-07-16
AR011729A1 (en) 2000-08-30
RU2175323C2 (en) 2001-10-27
DK0984960T3 (en) 2003-05-26
CN1263528A (en) 2000-08-16

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Legal Events

Date Code Title Description
A1OB Publication of a patent application
AIPI Request for the grant of a patent on the basis of a substantive examination of a patent application
PNAN Change of the applicant name, address/residence

Owner name: SANOFI-SYNTHELABO, FR

B1PR Patent granted
ODRP Renewal fee for the maintenance of a patent

Payment date: 20030429

Year of fee payment: 6

PBON Lapse due to non-payment of renewal fee

Effective date: 20040814